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The map label for this gene is prc [H]

Identifier: 66044844

GI number: 66044844

Start: 1797634

End: 1799748

Strand: Reverse

Name: prc [H]

Synonym: Psyr_1599

Alternate gene names: 66044844

Gene position: 1799748-1797634 (Counterclockwise)

Preceding gene: 66044846

Following gene: 66044843

Centisome position: 29.53

GC content: 58.49

Gene sequence:

>2115_bases
ATGCGTTATCAATTGTCCTCGCGTCGAATCAGCATGAAGCAACTATTCCCCAGCACTGCCCTCGCACTGTTTGTCGGCCT
TAGCGTTTTGCCGATGTCAGCCAGTACCTTTGCCGCCAACAGCTGGGATAATCTTCAGCCGGACCGCGACGAAGTGATTG
CCAGTCTCAACGTGGTTGAGCTGCTCAAACGACATCACTACAGCAAGCCGCCCCTGGACGACAAGCGTTCAGCGATTATT
TACCAGAGCTACATCAAGCAACTGGACCCCTCGCGCAGCTACTTCATGGCCAGCGACATTGCCGAGTTCGACAAATGGCA
GTTCCAGTTCGACGACTTCCTGAAGAGTGGCGACCTGAACGCCGGCTTCATCATCTACAAGCGCTATCTGGACCGCGTCA
ACGCGCGTCTGAACTTCGCGCTGGGCGAGTTGGGCAAGGGCGTCGACAAGCTCGACTTCAATACCAAGGAAACCCTGCTG
GTCGACCGCAAGGACGCCGCATGGCCCAAGGATACCGCCGAGCTCGACGAACTGTGGCGCAAGCGCATCAAGGATGAAGT
CCTGCGGTTGAAGATTGCAGGTAAGGATCCGGCGAAGATTCAGGAAACCCTGACCAAGCGCTATAAGAATCAGCAGGCGC
GTCTGAATCAGACTCGCGCCGAAGATATCTTCCAGGCCTACATCAACACGTTCGCCATGTCCTACGATCCGCACACCAAC
TACCTGTCACCTGACAGCGCGGAGAACTTCGACATCAACATGAGCCTGTCGCTGGAAGGCATCGGCGCCGTGTTGCAGAG
CGATAATGACAACGTGAAGATCGTGCGTCTGGTGCCGGCAGGTCCGGCGGCCAAGACCAAGCAGGTTGCCCCGGCCGACA
AGATCGTGGCCGTCGCTCAGGGCGACAAGGAAATGGTCGACGTGATCGGCTGGCGTCTGGATGAAGTGGTCAAGCTGATC
CGCGGTCCGAAAGGCTCGGTGGTACGCCTGGAGATCATCCCGGCCAGCAATGCGCCGAACGACCAGACCACCAAGATCGT
CGCCATCACCCGTGAAGCGGTGAAACTTGAAGAGCAGGCGGCCAAGAAGTCGATCCTGCACCTCAAGCAGGACGGCAAGG
ATTACAAGCTCGGGGTCATCGACATTCCGGCCTTCTATCTGGACTTCAAGGCCTACCGTGCCGGCGATCCGGAATACAAG
AGCACCACCCGTGACGTGAAGAAACTGCTCACCGAATTGCAGGCCGAGAAGGTCGACGGTGTGGTACTGGATCTGCGCAA
CAATGGTGGCGGTTCATTGCAGGAAGCCACCGAGCTGACCAGCCTGTTCATCGACAAAGGCCCGACCGTGCTGGTGCGCA
ATGCCGACGGCAAGGTCGACGTGCTGGAAGACGAAGCCAAGGGCGCGTTCTACAAAGGCCCGATGGCACTGCTGGTCAAC
CGTCTGTCTGCGTCGGCGTCGGAGATTTTCGCCGGGGCGATGCAGGATTATCACCGCGCGCTGGTGATCGGTGGTCAGAC
CTTCGGTAAAGGCACCGTGCAGACCATTCAGCCGCTCAATCACGGCGAACTGAAACTGACCCTGGCCAAGTTCTACCGGG
TTTCCGGTCAGAGCACCCAGCATCAGGGCGTAGTACCGGACATCACTTACCCGTCGCTGATCGACACCAAGGAAATCGGC
GAGAGCGCGCTGCCCGAGGCCATGCCGTGGGACAGCATCAAACCGGCGATCAAGCCGGCGATCGACCCGTTCAGGCCGTT
CTTGGCCCAACTGCAGGCGCGTCACGAGGCACGTTCGGCAAAAGACGCCGAGTTCGTGTTCATCGAGGATCGCCTGGCGC
TGGCCAAGAAGCTGATGAACGAGAAGACCGTCAGCCTCAATGAAGCCGACCGTCGTGCCGAGCATGCGTCTATCGAAAGC
AAGCAACTTGCGCTGGAAAACACCCGCCGCAAGGCCAAGGGTGAAGAACCGCTCAAAGAGCTGAAGAAGGAAGACGAAGA
CGCGCTGCCGGTGGAAGACGAGAAAACCAAACCCGAGGACGATGCCTATCTGGCAGAGACCGGGCGCATTCTCATCGACT
ACCTGGGTCTGAGTGCCGCTGTCGCGAAAAAGTAA

Upstream 100 bases:

>100_bases
CTCCATAGTGAGTCCAGACTGAGCCCGTGGCTGTTTTGCCCGGGCTTTTGCATTATGCGGCCGGGTCCAAAGGAACCGGC
GACCTCAAAGACGGCCTAAT

Downstream 100 bases:

>100_bases
CGCAGGATCATTGATGGCCATTTAGCTTCAACGTCATCAAACAGTCATGAAGCTGTCGTGAAATACGGGGCTGAACGCGA
AAGCGCTCAGCCCTTTTTCA

Product: peptidase S41A, C-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 704; Mature: 704

Protein sequence:

>704_residues
MRYQLSSRRISMKQLFPSTALALFVGLSVLPMSASTFAANSWDNLQPDRDEVIASLNVVELLKRHHYSKPPLDDKRSAII
YQSYIKQLDPSRSYFMASDIAEFDKWQFQFDDFLKSGDLNAGFIIYKRYLDRVNARLNFALGELGKGVDKLDFNTKETLL
VDRKDAAWPKDTAELDELWRKRIKDEVLRLKIAGKDPAKIQETLTKRYKNQQARLNQTRAEDIFQAYINTFAMSYDPHTN
YLSPDSAENFDINMSLSLEGIGAVLQSDNDNVKIVRLVPAGPAAKTKQVAPADKIVAVAQGDKEMVDVIGWRLDEVVKLI
RGPKGSVVRLEIIPASNAPNDQTTKIVAITREAVKLEEQAAKKSILHLKQDGKDYKLGVIDIPAFYLDFKAYRAGDPEYK
STTRDVKKLLTELQAEKVDGVVLDLRNNGGGSLQEATELTSLFIDKGPTVLVRNADGKVDVLEDEAKGAFYKGPMALLVN
RLSASASEIFAGAMQDYHRALVIGGQTFGKGTVQTIQPLNHGELKLTLAKFYRVSGQSTQHQGVVPDITYPSLIDTKEIG
ESALPEAMPWDSIKPAIKPAIDPFRPFLAQLQARHEARSAKDAEFVFIEDRLALAKKLMNEKTVSLNEADRRAEHASIES
KQLALENTRRKAKGEEPLKELKKEDEDALPVEDEKTKPEDDAYLAETGRILIDYLGLSAAVAKK

Sequences:

>Translated_704_residues
MRYQLSSRRISMKQLFPSTALALFVGLSVLPMSASTFAANSWDNLQPDRDEVIASLNVVELLKRHHYSKPPLDDKRSAII
YQSYIKQLDPSRSYFMASDIAEFDKWQFQFDDFLKSGDLNAGFIIYKRYLDRVNARLNFALGELGKGVDKLDFNTKETLL
VDRKDAAWPKDTAELDELWRKRIKDEVLRLKIAGKDPAKIQETLTKRYKNQQARLNQTRAEDIFQAYINTFAMSYDPHTN
YLSPDSAENFDINMSLSLEGIGAVLQSDNDNVKIVRLVPAGPAAKTKQVAPADKIVAVAQGDKEMVDVIGWRLDEVVKLI
RGPKGSVVRLEIIPASNAPNDQTTKIVAITREAVKLEEQAAKKSILHLKQDGKDYKLGVIDIPAFYLDFKAYRAGDPEYK
STTRDVKKLLTELQAEKVDGVVLDLRNNGGGSLQEATELTSLFIDKGPTVLVRNADGKVDVLEDEAKGAFYKGPMALLVN
RLSASASEIFAGAMQDYHRALVIGGQTFGKGTVQTIQPLNHGELKLTLAKFYRVSGQSTQHQGVVPDITYPSLIDTKEIG
ESALPEAMPWDSIKPAIKPAIDPFRPFLAQLQARHEARSAKDAEFVFIEDRLALAKKLMNEKTVSLNEADRRAEHASIES
KQLALENTRRKAKGEEPLKELKKEDEDALPVEDEKTKPEDDAYLAETGRILIDYLGLSAAVAKK
>Mature_704_residues
MRYQLSSRRISMKQLFPSTALALFVGLSVLPMSASTFAANSWDNLQPDRDEVIASLNVVELLKRHHYSKPPLDDKRSAII
YQSYIKQLDPSRSYFMASDIAEFDKWQFQFDDFLKSGDLNAGFIIYKRYLDRVNARLNFALGELGKGVDKLDFNTKETLL
VDRKDAAWPKDTAELDELWRKRIKDEVLRLKIAGKDPAKIQETLTKRYKNQQARLNQTRAEDIFQAYINTFAMSYDPHTN
YLSPDSAENFDINMSLSLEGIGAVLQSDNDNVKIVRLVPAGPAAKTKQVAPADKIVAVAQGDKEMVDVIGWRLDEVVKLI
RGPKGSVVRLEIIPASNAPNDQTTKIVAITREAVKLEEQAAKKSILHLKQDGKDYKLGVIDIPAFYLDFKAYRAGDPEYK
STTRDVKKLLTELQAEKVDGVVLDLRNNGGGSLQEATELTSLFIDKGPTVLVRNADGKVDVLEDEAKGAFYKGPMALLVN
RLSASASEIFAGAMQDYHRALVIGGQTFGKGTVQTIQPLNHGELKLTLAKFYRVSGQSTQHQGVVPDITYPSLIDTKEIG
ESALPEAMPWDSIKPAIKPAIDPFRPFLAQLQARHEARSAKDAEFVFIEDRLALAKKLMNEKTVSLNEADRRAEHASIES
KQLALENTRRKAKGEEPLKELKKEDEDALPVEDEKTKPEDDAYLAETGRILIDYLGLSAAVAKK

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=709, Percent_Identity=43.0183356840621, Blast_Score=482, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 78643; Mature: 78643

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYQLSSRRISMKQLFPSTALALFVGLSVLPMSASTFAANSWDNLQPDRDEVIASLNVVE
CCCCCCCCCHHHHHHCHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHHH
LLKRHHYSKPPLDDKRSAIIYQSYIKQLDPSRSYFMASDIAEFDKWQFQFDDFLKSGDLN
HHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGFIIYKRYLDRVNARLNFALGELGKGVDKLDFNTKETLLVDRKDAAWPKDTAELDELWR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHH
KRIKDEVLRLKIAGKDPAKIQETLTKRYKNQQARLNQTRAEDIFQAYINTFAMSYDPHTN
HHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
YLSPDSAENFDINMSLSLEGIGAVLQSDNDNVKIVRLVPAGPAAKTKQVAPADKIVAVAQ
CCCCCCCCCEEEEEEEEHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHHEEEEEC
GDKEMVDVIGWRLDEVVKLIRGPKGSVVRLEIIPASNAPNDQTTKIVAITREAVKLEEQA
CCHHHHHHHHCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEEEEEEEHHHHHHHHHH
AKKSILHLKQDGKDYKLGVIDIPAFYLDFKAYRAGDPEYKSTTRDVKKLLTELQAEKVDG
HHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
VVLDLRNNGGGSLQEATELTSLFIDKGPTVLVRNADGKVDVLEDEAKGAFYKGPMALLVN
EEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCEECCCHHHHHH
RLSASASEIFAGAMQDYHRALVIGGQTFGKGTVQTIQPLNHGELKLTLAKFYRVSGQSTQ
HHHCCHHHHHHHHHHHHCEEEEECCCCCCCCCHHHCCCCCCCCEEEEHHHHHHHCCCCCC
HQGVVPDITYPSLIDTKEIGESALPEAMPWDSIKPAIKPAIDPFRPFLAQLQARHEARSA
CCCCCCCCCCCCCCCHHHHCHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCC
KDAEFVFIEDRLALAKKLMNEKTVSLNEADRRAEHASIESKQLALENTRRKAKGEEPLKE
CCCEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHH
LKKEDEDALPVEDEKTKPEDDAYLAETGRILIDYLGLSAAVAKK
HHHCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHCCHHHHHCC
>Mature Secondary Structure
MRYQLSSRRISMKQLFPSTALALFVGLSVLPMSASTFAANSWDNLQPDRDEVIASLNVVE
CCCCCCCCCHHHHHHCHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHHH
LLKRHHYSKPPLDDKRSAIIYQSYIKQLDPSRSYFMASDIAEFDKWQFQFDDFLKSGDLN
HHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGFIIYKRYLDRVNARLNFALGELGKGVDKLDFNTKETLLVDRKDAAWPKDTAELDELWR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHH
KRIKDEVLRLKIAGKDPAKIQETLTKRYKNQQARLNQTRAEDIFQAYINTFAMSYDPHTN
HHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
YLSPDSAENFDINMSLSLEGIGAVLQSDNDNVKIVRLVPAGPAAKTKQVAPADKIVAVAQ
CCCCCCCCCEEEEEEEEHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHHEEEEEC
GDKEMVDVIGWRLDEVVKLIRGPKGSVVRLEIIPASNAPNDQTTKIVAITREAVKLEEQA
CCHHHHHHHHCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEEEEEEEHHHHHHHHHH
AKKSILHLKQDGKDYKLGVIDIPAFYLDFKAYRAGDPEYKSTTRDVKKLLTELQAEKVDG
HHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
VVLDLRNNGGGSLQEATELTSLFIDKGPTVLVRNADGKVDVLEDEAKGAFYKGPMALLVN
EEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCEECCCHHHHHH
RLSASASEIFAGAMQDYHRALVIGGQTFGKGTVQTIQPLNHGELKLTLAKFYRVSGQSTQ
HHHCCHHHHHHHHHHHHCEEEEECCCCCCCCCHHHCCCCCCCCEEEEHHHHHHHCCCCCC
HQGVVPDITYPSLIDTKEIGESALPEAMPWDSIKPAIKPAIDPFRPFLAQLQARHEARSA
CCCCCCCCCCCCCCCHHHHCHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCC
KDAEFVFIEDRLALAKKLMNEKTVSLNEADRRAEHASIESKQLALENTRRKAKGEEPLKE
CCCEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHH
LKKEDEDALPVEDEKTKPEDDAYLAETGRILIDYLGLSAAVAKK
HHHCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]