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The map label for this gene is pgi [H]

Identifier: 66044081

GI number: 66044081

Start: 934924

End: 936588

Strand: Reverse

Name: pgi [H]

Synonym: Psyr_0826

Alternate gene names: 66044081

Gene position: 936588-934924 (Counterclockwise)

Preceding gene: 66044082

Following gene: 66044080

Centisome position: 15.37

GC content: 61.02

Gene sequence:

>1665_bases
ATGGCGTACTACCGCACTCCTTCCGATGTGACCGCTCTGCCCGCCTGGCAAGCGTTGAACAAACACCGCCAGGCCATGCA
GAACTTCAGCATGCGCGAAGCGTTCAACACCGACCCGCAGCGCTTCAGCCAATTCACCCTCAGCAGCGCCGGTCTGTTTC
TCGATTATTCCAAAAACCTGATCACCACCGAGACCCGCGACCTGTTGGTCAGCCTGGCGGGCGAAGTGGGCCTCAAGGAC
GCGATCAAGGCTCAGTATGATGGCGAGCTGGTCAACTCATCCGAAGGCCGCCCTGCCCTGCACACCGCTCTGCGCCGCCC
GGTCGGCGACAAGTTGAAAGTCAACGGCGTCGATGTGATGCCGGACGTACACCGCGTCCTCAATCAGATGACCGAACTGG
TCGGCCGCATCCATGACGGCCTGTGGCGCGGTTATACCGAAAAACCGATCACCGACGTGGTGAACATCGGCATCGGCGGC
TCGTTCCTCGGCCCGGAGCTGGTCTCCGAAGCGCTGGTGGCCTACGCGCACAAAGGTGTCCGCTGCCATTACCTGGCCAA
CATCGACGGCAGCGAGTTCCATGAGCTGTCGATGAAGATTCGTGCCGAGACCACGCTGTTCATCGTCTCGTCGAAATCCT
TCAATACGCTGGAAACCCTGAAAAACGCGCAGGCTGCACGCGCCTGGTACCTGGCGCAGGGCGGCTCGGAAGTCGAACTG
CATCGCCACTTCATCGCGGTGTCCAGCAACAACGCGGCGGCCGTGGCCTTCGGCATCCGTGAAGAAAACATCTTCCCTAT
GTGGGACTGGGTCGGCGGTCGCTATTCGCTGTGGTCGGCCATCGGTCTGCCTATCGCGCTGGCCATCGGCATGTCCAACT
TCAAGGAACTGCTGTCCGGTGCCTACACCATGGACCAGCATTTCCAGAGCGCACCGTTCGAACAGAACATGCCGGTATTA
CTGGGCTTGCTGGGCGTCTGGTACGGCAATTTCTGGAACGCACAAAGCCACGCGATCCTGCCGTACGACCACTACCTGCG
CAACATCACCAAGCACTTGCAACAACTGGACATGGAATCCAACGGCAAGAGCGTCCGTCAGGACGGTACGCCGACCTCGA
CCGACACCGGACCGGTGATCTGGGGCGGCGTGGGTGCCAACGGTCAGCACGCTTACCACCAGTTGCTGCACCAGGGCACG
CAGATGATTCCGGCCGACTTCATTGTGCCGATCGTCAGCTTCAACCCGGTTGCCGACCATCACCAGTGGCTGTACGCCAA
CTGTCTGTCGCAGAGCCAGGCACTGATGATGGGCAAGACCCGCGCAGAAGCCGAAGCAGAACTGCGCGAGAAGGGTATGG
ACGAGCAAGAGGTGCAGAAGCTGGCACCGCACAAGGTCATCCCTGGCAACCGTCCGAGCAACACGCTGGTGGTCGAGCGC
ATCAGCCCGCGTCGTCTTGGCGCGCTGGTGGCCATGTATGAACACAAGGTGTTCGTGCAGAGCGTGATCTGGGGCACCAA
CGCCTTTGACCAATGGGGTGTGGAGCTGGGCAAGGAAATGGGCAAGGCGGTGTACCAGCGTCTGACCGGCGGCACCGAAG
AGCAGGCTGACGATGCATCGACCCAAGGCCTGATCAACTACTTCCGCGGCCGTCACCGCGGCTGA

Upstream 100 bases:

>100_bases
GTACGCGAAGGGTAGTCTGCGATGTGTAGCCCGTGAGAAAGCTTGCGACCTCGCTCCAAGAATATCCAAAGACAGAACCA
GTTAAAGGAAACCCGCAGCG

Downstream 100 bases:

>100_bases
TTGTTTCCCTCTCGTTCCCACGCTCTGCGCTCAGCGTTACGCAGAAGTCTTGATGAGTAGGGGAAACGGGGCTTTTGTAG
GAGCGACCGGGGCGGCGATC

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MAYYRTPSDVTALPAWQALNKHRQAMQNFSMREAFNTDPQRFSQFTLSSAGLFLDYSKNLITTETRDLLVSLAGEVGLKD
AIKAQYDGELVNSSEGRPALHTALRRPVGDKLKVNGVDVMPDVHRVLNQMTELVGRIHDGLWRGYTEKPITDVVNIGIGG
SFLGPELVSEALVAYAHKGVRCHYLANIDGSEFHELSMKIRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEVEL
HRHFIAVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIGLPIALAIGMSNFKELLSGAYTMDQHFQSAPFEQNMPVL
LGLLGVWYGNFWNAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPTSTDTGPVIWGGVGANGQHAYHQLLHQGT
QMIPADFIVPIVSFNPVADHHQWLYANCLSQSQALMMGKTRAEAEAELREKGMDEQEVQKLAPHKVIPGNRPSNTLVVER
ISPRRLGALVAMYEHKVFVQSVIWGTNAFDQWGVELGKEMGKAVYQRLTGGTEEQADDASTQGLINYFRGRHRG

Sequences:

>Translated_554_residues
MAYYRTPSDVTALPAWQALNKHRQAMQNFSMREAFNTDPQRFSQFTLSSAGLFLDYSKNLITTETRDLLVSLAGEVGLKD
AIKAQYDGELVNSSEGRPALHTALRRPVGDKLKVNGVDVMPDVHRVLNQMTELVGRIHDGLWRGYTEKPITDVVNIGIGG
SFLGPELVSEALVAYAHKGVRCHYLANIDGSEFHELSMKIRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEVEL
HRHFIAVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIGLPIALAIGMSNFKELLSGAYTMDQHFQSAPFEQNMPVL
LGLLGVWYGNFWNAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPTSTDTGPVIWGGVGANGQHAYHQLLHQGT
QMIPADFIVPIVSFNPVADHHQWLYANCLSQSQALMMGKTRAEAEAELREKGMDEQEVQKLAPHKVIPGNRPSNTLVVER
ISPRRLGALVAMYEHKVFVQSVIWGTNAFDQWGVELGKEMGKAVYQRLTGGTEEQADDASTQGLINYFRGRHRG
>Mature_553_residues
AYYRTPSDVTALPAWQALNKHRQAMQNFSMREAFNTDPQRFSQFTLSSAGLFLDYSKNLITTETRDLLVSLAGEVGLKDA
IKAQYDGELVNSSEGRPALHTALRRPVGDKLKVNGVDVMPDVHRVLNQMTELVGRIHDGLWRGYTEKPITDVVNIGIGGS
FLGPELVSEALVAYAHKGVRCHYLANIDGSEFHELSMKIRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEVELH
RHFIAVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIGLPIALAIGMSNFKELLSGAYTMDQHFQSAPFEQNMPVLL
GLLGVWYGNFWNAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPTSTDTGPVIWGGVGANGQHAYHQLLHQGTQ
MIPADFIVPIVSFNPVADHHQWLYANCLSQSQALMMGKTRAEAEAELREKGMDEQEVQKLAPHKVIPGNRPSNTLVVERI
SPRRLGALVAMYEHKVFVQSVIWGTNAFDQWGVELGKEMGKAVYQRLTGGTEEQADDASTQGLINYFRGRHRG

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=547, Percent_Identity=47.1663619744059, Blast_Score=551, Evalue=1e-157,
Organism=Homo sapiens, GI296080693, Length=547, Percent_Identity=43.6928702010969, Blast_Score=498, Evalue=1e-141,
Organism=Escherichia coli, GI1790457, Length=541, Percent_Identity=48.7985212569316, Blast_Score=550, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71996708, Length=538, Percent_Identity=48.6988847583643, Blast_Score=546, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI71996703, Length=538, Percent_Identity=48.6988847583643, Blast_Score=545, Evalue=1e-155,
Organism=Saccharomyces cerevisiae, GI6319673, Length=549, Percent_Identity=44.08014571949, Blast_Score=473, Evalue=1e-134,
Organism=Drosophila melanogaster, GI24651916, Length=544, Percent_Identity=49.2647058823529, Blast_Score=551, Evalue=1e-157,
Organism=Drosophila melanogaster, GI24651914, Length=544, Percent_Identity=49.2647058823529, Blast_Score=551, Evalue=1e-157,
Organism=Drosophila melanogaster, GI17737445, Length=544, Percent_Identity=49.2647058823529, Blast_Score=551, Evalue=1e-157,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 61638; Mature: 61506

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYYRTPSDVTALPAWQALNKHRQAMQNFSMREAFNTDPQRFSQFTLSSAGLFLDYSKNL
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHCCCEEEEECCCE
ITTETRDLLVSLAGEVGLKDAIKAQYDGELVNSSEGRPALHTALRRPVGDKLKVNGVDVM
ECHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCEECC
PDVHRVLNQMTELVGRIHDGLWRGYTEKPITDVVNIGIGGSFLGPELVSEALVAYAHKGV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
RCHYLANIDGSEFHELSMKIRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEVEL
EEEEEECCCCCHHHHHHEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHEECCCCEEEE
HRHFIAVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIGLPIALAIGMSNFKELLSG
EEEEEEEECCCCEEEEEECCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AYTMDQHFQSAPFEQNMPVLLGLLGVWYGNFWNAQSHAILPYDHYLRNITKHLQQLDMES
HHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCC
NGKSVRQDGTPTSTDTGPVIWGGVGANGQHAYHQLLHQGTQMIPADFIVPIVSFNPVADH
CCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHH
HQWLYANCLSQSQALMMGKTRAEAEAELREKGMDEQEVQKLAPHKVIPGNRPSNTLVVER
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCEEEEC
ISPRRLGALVAMYEHKVFVQSVIWGTNAFDQWGVELGKEMGKAVYQRLTGGTEEQADDAS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHH
TQGLINYFRGRHRG
HHHHHHHHHCCCCC
>Mature Secondary Structure 
AYYRTPSDVTALPAWQALNKHRQAMQNFSMREAFNTDPQRFSQFTLSSAGLFLDYSKNL
CCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHCCCEEEEECCCE
ITTETRDLLVSLAGEVGLKDAIKAQYDGELVNSSEGRPALHTALRRPVGDKLKVNGVDVM
ECHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCEECC
PDVHRVLNQMTELVGRIHDGLWRGYTEKPITDVVNIGIGGSFLGPELVSEALVAYAHKGV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
RCHYLANIDGSEFHELSMKIRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEVEL
EEEEEECCCCCHHHHHHEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHEECCCCEEEE
HRHFIAVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIGLPIALAIGMSNFKELLSG
EEEEEEEECCCCEEEEEECCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AYTMDQHFQSAPFEQNMPVLLGLLGVWYGNFWNAQSHAILPYDHYLRNITKHLQQLDMES
HHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCC
NGKSVRQDGTPTSTDTGPVIWGGVGANGQHAYHQLLHQGTQMIPADFIVPIVSFNPVADH
CCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHH
HQWLYANCLSQSQALMMGKTRAEAEAELREKGMDEQEVQKLAPHKVIPGNRPSNTLVVER
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCEEEEC
ISPRRLGALVAMYEHKVFVQSVIWGTNAFDQWGVELGKEMGKAVYQRLTGGTEEQADDAS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHH
TQGLINYFRGRHRG
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA