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The map label for this gene is panC [H]

Identifier: 66044082

GI number: 66044082

Start: 936842

End: 937693

Strand: Reverse

Name: panC [H]

Synonym: Psyr_0827

Alternate gene names: 66044082

Gene position: 937693-936842 (Counterclockwise)

Preceding gene: 66044083

Following gene: 66044081

Centisome position: 15.39

GC content: 61.97

Gene sequence:

>852_bases
ATGAACACAGTAAAAACCTTACAGGACCTGCGCGCCGCCGTTGCGCGGGCACGCAGCGAAGGCAAGCGGATCGCGCTGAC
CCCGACGATGGGCAACCTGCACAGCGGCCACGCCGCGCTGGTCACCAAGGCGGCGCAGCGTGCCGATTTCGTGGTCGCCA
CTATTTTCGTCAATCCGCTGCAGTTCGGCCCCAACGAAGACCTGGCCACCTACCCTCGCACGCTGGCTGCCGATCAAGAA
AAACTCCTGCAGGCCGGCTGCAATCTGCTGTTCACGCCCAGCGTGGAAGAAATGTACCCGCACGGCATGGCCGACCAGAC
ACTGGTCAGCGTGCCGCACCTGTCGCAAGGCCTGTGTGGCGCCAGCCGTCCCGGCCATTTCGAAGGTGTCGCGACCGTGG
TCAGCAAGCTGTTCAACATGGTGCAGCCTGACCTGGCGATTTTTGGTGAAAAAGACTTCCAGCAACTGGCCGTGATTCGG
GCCATGGTGCGTGATCTGAACATGCCGATCCAGATCATCGGCGAACCGACGGTACGCGCTGACGATGGTCTGGCGCTGTC
CTCGCGCAACGGGTATCTGAGCGACGATCAGCGCGCCGCGGCACCCGCGCTGTATCAAGCGATCCTCCAGACCGCCGACG
TGATCAGTGCCGGCGAACAGGATTTCGACGCATTGCTGGCGAGCAAGAAGCAGCAACTGGAGGCTGCCGGTTTTCGCATC
GACTATCTGGAGATACGCGATGCCACCAGCCTGCGTCCGGCGACTGCCGACAATCGCGAAGTGGTCATCCTCGCAGCGGC
ATTCCTGGGCAAAACCCGCTTGATCGACAACCTGCACCTGACCAGAAGCTGA

Upstream 100 bases:

>100_bases
ACTTCATGACCGGCCAGCCCGATATCCAGTCGGCTATCCGGGCCTACGTGACCGCCGTCAAAGACCTCAGCTTTCCGGCC
ACTGAACACGGATTCTCGGC

Downstream 100 bases:

>100_bases
CAGGATGTGCGCCGGCAATGAACTAAGGCACACCGGCAATGCCATACCGGTACAGGTTGCCTGAACCACAACCGACCGTA
TTCGTGACAAAGCCCCGGTT

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MNTVKTLQDLRAAVARARSEGKRIALTPTMGNLHSGHAALVTKAAQRADFVVATIFVNPLQFGPNEDLATYPRTLAADQE
KLLQAGCNLLFTPSVEEMYPHGMADQTLVSVPHLSQGLCGASRPGHFEGVATVVSKLFNMVQPDLAIFGEKDFQQLAVIR
AMVRDLNMPIQIIGEPTVRADDGLALSSRNGYLSDDQRAAAPALYQAILQTADVISAGEQDFDALLASKKQQLEAAGFRI
DYLEIRDATSLRPATADNREVVILAAAFLGKTRLIDNLHLTRS

Sequences:

>Translated_283_residues
MNTVKTLQDLRAAVARARSEGKRIALTPTMGNLHSGHAALVTKAAQRADFVVATIFVNPLQFGPNEDLATYPRTLAADQE
KLLQAGCNLLFTPSVEEMYPHGMADQTLVSVPHLSQGLCGASRPGHFEGVATVVSKLFNMVQPDLAIFGEKDFQQLAVIR
AMVRDLNMPIQIIGEPTVRADDGLALSSRNGYLSDDQRAAAPALYQAILQTADVISAGEQDFDALLASKKQQLEAAGFRI
DYLEIRDATSLRPATADNREVVILAAAFLGKTRLIDNLHLTRS
>Mature_283_residues
MNTVKTLQDLRAAVARARSEGKRIALTPTMGNLHSGHAALVTKAAQRADFVVATIFVNPLQFGPNEDLATYPRTLAADQE
KLLQAGCNLLFTPSVEEMYPHGMADQTLVSVPHLSQGLCGASRPGHFEGVATVVSKLFNMVQPDLAIFGEKDFQQLAVIR
AMVRDLNMPIQIIGEPTVRADDGLALSSRNGYLSDDQRAAAPALYQAILQTADVISAGEQDFDALLASKKQQLEAAGFRI
DYLEIRDATSLRPATADNREVVILAAAFLGKTRLIDNLHLTRS

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=277, Percent_Identity=56.6787003610108, Blast_Score=317, Evalue=4e-88,
Organism=Saccharomyces cerevisiae, GI6322046, Length=304, Percent_Identity=35.5263157894737, Blast_Score=179, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 30636; Mature: 30636

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVKTLQDLRAAVARARSEGKRIALTPTMGNLHSGHAALVTKAAQRADFVVATIFVNPL
CCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCEEEEEEEECHH
QFGPNEDLATYPRTLAADQEKLLQAGCNLLFTPSVEEMYPHGMADQTLVSVPHLSQGLCG
CCCCCCCHHHCCHHHHHHHHHHHHHCCCEEECCCHHHHCCCCCCCCCEEECCCHHCCCCC
ASRPGHFEGVATVVSKLFNMVQPDLAIFGEKDFQQLAVIRAMVRDLNMPIQIIGEPTVRA
CCCCCCHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEC
DDGLALSSRNGYLSDDQRAAAPALYQAILQTADVISAGEQDFDALLASKKQQLEAAGFRI
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEE
DYLEIRDATSLRPATADNREVVILAAAFLGKTRLIDNLHLTRS
EEEEECCCCCCCCCCCCCCEEEEEEHHHHCHHHHHHCCCCCCC
>Mature Secondary Structure
MNTVKTLQDLRAAVARARSEGKRIALTPTMGNLHSGHAALVTKAAQRADFVVATIFVNPL
CCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCEEEEEEEECHH
QFGPNEDLATYPRTLAADQEKLLQAGCNLLFTPSVEEMYPHGMADQTLVSVPHLSQGLCG
CCCCCCCHHHCCHHHHHHHHHHHHHCCCEEECCCHHHHCCCCCCCCCEEECCCHHCCCCC
ASRPGHFEGVATVVSKLFNMVQPDLAIFGEKDFQQLAVIRAMVRDLNMPIQIIGEPTVRA
CCCCCCHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEC
DDGLALSSRNGYLSDDQRAAAPALYQAILQTADVISAGEQDFDALLASKKQQLEAAGFRI
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEE
DYLEIRDATSLRPATADNREVVILAAAFLGKTRLIDNLHLTRS
EEEEECCCCCCCCCCCCCCEEEEEEHHHHCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA