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The map label for this gene is pcbC [H]

Identifier: 66043929

GI number: 66043929

Start: 750397

End: 751362

Strand: Reverse

Name: pcbC [H]

Synonym: Psyr_0662

Alternate gene names: 66043929

Gene position: 751362-750397 (Counterclockwise)

Preceding gene: 66043930

Following gene: 66043928

Centisome position: 12.33

GC content: 62.84

Gene sequence:

>966_bases
ATGGACCAGCTTCCCGTCATCGACATCGCCCCGCTCTACGGCACGGAAACTCAGGCCTGGCAGGATGTCGCCCGGCAAAT
CGACAGTGCCTGTCGGGCGTGGGGCTTCTTTTACATCAAGGGCCACCCAATCAGCGCGCAACGCATCGAACAGGTGCAAT
CGGCGGCAAAGGACTTCTTCGCCCGGCCGGCAGCTGAAAAGCTCCTGATCGACATCACCCAAAGCACGCACCATCGCGGC
TACGGCGCCATCGCCACCGAACAACTGGACCCCAGCCTGCCGAGCGACCTCAAGGAAACCTTCGACATGGGCCTGCACCT
GGATGCCCGTCATCCCGACGTGCTGGCGGGTAAACCGCTGCGTGGGCCAAACCGGCATCCGGACATTCCCGGCTGGGAAA
CCCTGATGGAGCAACACTATCTGGACATGCAGGCGCTGGCGCAAACCCTGCTGCGCGCCATGACCCTGGCACTGGGCATC
GAGCGCGATTTCTTCGATCAGCGCTTCAAGGACCCGGTCAGCGTACTGCGCATGATTCATTACCCGCCGCGTGGTACGGC
GACCTCAGCCGAGCAACAAGGCGCAGGCGCGCATACCGATTACGGCTGCATCACCCTGCTGTATCAGGACACGGCGGGCG
GCTTGCAGGTGCGTGATGTGCGTGGCGAATGGATCGACGCGCCACCGCTTGACGGCACCTTCGTGGTCAATCTGGGCGAC
ATGATGGCGCGCTGGAGCAACGATCGTTATCTGTCCACGCCGCACCGGGTCATCAGCCCGCTCGGGGTTGATCGCTACTC
CATGCCGTTCTTTGCCGAACCGCACCCCGACACGCGCATCGAATGCCTGCCTGGTTGCCAGAGCGACGATCATCCGGCCC
GCTATCCGGTGACCACCTGCGCCGAATTTCTGCTGTCGCGCTTCGCGGATACCTACGCTTATCGCCGCGAACAGGAGGCA
AGTTGA

Upstream 100 bases:

>100_bases
TCAAGGCCGAGCTGCCGAAGTAATCAGCCCGTCAGCTGCCTGACCATCGTGCCTGCCGCGCCAGGCACGATCATCGACAC
TTCCCTTTCAGGACCGGTTA

Downstream 100 bases:

>100_bases
ACGTTCGGTCAGGTTTTACCCTGCGCAGCGACGTGCATCTGTAGAATGCCCGGGATCTGCACCTGATGAGAAAAGAATAT
GTACGACTGGTTGAACGCCC

Product: 2OG-Fe(II) oxygenase family protein

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MDQLPVIDIAPLYGTETQAWQDVARQIDSACRAWGFFYIKGHPISAQRIEQVQSAAKDFFARPAAEKLLIDITQSTHHRG
YGAIATEQLDPSLPSDLKETFDMGLHLDARHPDVLAGKPLRGPNRHPDIPGWETLMEQHYLDMQALAQTLLRAMTLALGI
ERDFFDQRFKDPVSVLRMIHYPPRGTATSAEQQGAGAHTDYGCITLLYQDTAGGLQVRDVRGEWIDAPPLDGTFVVNLGD
MMARWSNDRYLSTPHRVISPLGVDRYSMPFFAEPHPDTRIECLPGCQSDDHPARYPVTTCAEFLLSRFADTYAYRREQEA
S

Sequences:

>Translated_321_residues
MDQLPVIDIAPLYGTETQAWQDVARQIDSACRAWGFFYIKGHPISAQRIEQVQSAAKDFFARPAAEKLLIDITQSTHHRG
YGAIATEQLDPSLPSDLKETFDMGLHLDARHPDVLAGKPLRGPNRHPDIPGWETLMEQHYLDMQALAQTLLRAMTLALGI
ERDFFDQRFKDPVSVLRMIHYPPRGTATSAEQQGAGAHTDYGCITLLYQDTAGGLQVRDVRGEWIDAPPLDGTFVVNLGD
MMARWSNDRYLSTPHRVISPLGVDRYSMPFFAEPHPDTRIECLPGCQSDDHPARYPVTTCAEFLLSRFADTYAYRREQEA
S
>Mature_321_residues
MDQLPVIDIAPLYGTETQAWQDVARQIDSACRAWGFFYIKGHPISAQRIEQVQSAAKDFFARPAAEKLLIDITQSTHHRG
YGAIATEQLDPSLPSDLKETFDMGLHLDARHPDVLAGKPLRGPNRHPDIPGWETLMEQHYLDMQALAQTLLRAMTLALGI
ERDFFDQRFKDPVSVLRMIHYPPRGTATSAEQQGAGAHTDYGCITLLYQDTAGGLQVRDVRGEWIDAPPLDGTFVVNLGD
MMARWSNDRYLSTPHRVISPLGVDRYSMPFFAEPHPDTRIECLPGCQSDDHPARYPVTTCAEFLLSRFADTYAYRREQEA
S

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI28572124, Length=338, Percent_Identity=26.0355029585799, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI85816264, Length=300, Percent_Identity=26.3333333333333, Blast_Score=88, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 36129; Mature: 36129

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQLPVIDIAPLYGTETQAWQDVARQIDSACRAWGFFYIKGHPISAQRIEQVQSAAKDFF
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHH
ARPAAEKLLIDITQSTHHRGYGAIATEQLDPSLPSDLKETFDMGLHLDARHPDVLAGKPL
HCCCHHHHEEEHHHCCCCCCCCCEEHHCCCCCCCHHHHHHHHCCCEECCCCCCCCCCCCC
RGPNRHPDIPGWETLMEQHYLDMQALAQTLLRAMTLALGIERDFFDQRFKDPVSVLRMIH
CCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHC
YPPRGTATSAEQQGAGAHTDYGCITLLYQDTAGGLQVRDVRGEWIDAPPLDGTFVVNLGD
CCCCCCCCCHHHCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEEEHHH
MMARWSNDRYLSTPHRVISPLGVDRYSMPFFAEPHPDTRIECLPGCQSDDHPARYPVTTC
HHHHHCCCCEECCHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHH
AEFLLSRFADTYAYRREQEAS
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDQLPVIDIAPLYGTETQAWQDVARQIDSACRAWGFFYIKGHPISAQRIEQVQSAAKDFF
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHH
ARPAAEKLLIDITQSTHHRGYGAIATEQLDPSLPSDLKETFDMGLHLDARHPDVLAGKPL
HCCCHHHHEEEHHHCCCCCCCCCEEHHCCCCCCCHHHHHHHHCCCEECCCCCCCCCCCCC
RGPNRHPDIPGWETLMEQHYLDMQALAQTLLRAMTLALGIERDFFDQRFKDPVSVLRMIH
CCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHC
YPPRGTATSAEQQGAGAHTDYGCITLLYQDTAGGLQVRDVRGEWIDAPPLDGTFVVNLGD
CCCCCCCCCHHHCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEEEHHH
MMARWSNDRYLSTPHRVISPLGVDRYSMPFFAEPHPDTRIECLPGCQSDDHPARYPVTTC
HHHHHCCCCEECCHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHH
AEFLLSRFADTYAYRREQEAS
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1956290 [H]