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The map label for this gene is add [H]

Identifier: 66043928

GI number: 66043928

Start: 749365

End: 750318

Strand: Reverse

Name: add [H]

Synonym: Psyr_0661

Alternate gene names: 66043928

Gene position: 750318-749365 (Counterclockwise)

Preceding gene: 66043929

Following gene: 66043925

Centisome position: 12.31

GC content: 61.43

Gene sequence:

>954_bases
ATGTACGACTGGTTGAACGCCCTGCCCAAGGCAGAACTGCACTTGCACCTCGAAGGCTCGCTGGAACCCGAGTTGCTGTT
CGCCCTGGCCGAGCGCAACAGGATTGCCCTGCCGTGGGATGACGTCGAAACCCTGCGCAAGGCATATGCCTTCAACAACC
TGCAGGAATTCCTCGACCTGTATTACCGGGGCGCGGACGTATTGCGCACCGAGCAGGACTTCTACGACCTGACCTGGGCC
TACCTGCTGCGCTGCAAGGCACAGAACGTTGTCCACACCGAACCGTTCTTCGATCCGCAAACCCACACCGACCGTGGCAT
CCCGTTCGAAGTGGTACTGGCCGGGATTACCGGTGCGCTGAAAGACGGCAAGTCGAAGCTGGGCGTCGACAGCGGCCTGA
TCCTGAGCTTCCTGCGTCACCTGTCCCAGGAAGAGGCCGAAAAAACCCTCGATCAGGCGCTGCCGTTCCGTGATGCGTTC
GTCGCCGTGGGCCTCGACAGCTCGGAAATGGGTCACCCGCCAAGCAAGTTCCAGCGTGTGTTCGATCGCGCGCGCAACGA
GGGCTTCCTGACCGTGGCCCACGCCGGAGAAGAAGGTCCGCCGGAATACATCTGGGAAGCACTGGACCTGCTGAAGATCC
AGCGCATCGACCACGGTGTGCGCGCCATCGAAGACGAGCGGCTGATGCAGCGCATCATCGACGAACAGATCCCGCTGACC
GTCTGCCCGCTGTCCAACACCAAGCTTTGCGTGTTCGACGACATGGCCCAGCACAACATCCTCGACATGCTCGAGCGCGG
CGTGAAGGTCACCGTCAATTCGGACGACCCGGCCTACTTCGGTGGCTACGTGACCGAGAACTTCCACGCGCTGTACACCC
ACCTGGGCATGACCGAAGATCAGGCCAAACGCCTGGCGCAAAACAGCCTGGATGCACGACTGGTCAAGCCCTAG

Upstream 100 bases:

>100_bases
CCGCGAACAGGAGGCAAGTTGAACGTTCGGTCAGGTTTTACCCTGCGCAGCGACGTGCATCTGTAGAATGCCCGGGATCT
GCACCTGATGAGAAAAGAAT

Downstream 100 bases:

>100_bases
AGAGTGATTGAGCGGCTACCCCCATCGTTCCTCACGCTCCGCGTGGCAATGCCTTTCGCGACGCTCTGCGTCGCAAGAGG
ACGCGGAGCGTCCGGAACTG

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MYDWLNALPKAELHLHLEGSLEPELLFALAERNRIALPWDDVETLRKAYAFNNLQEFLDLYYRGADVLRTEQDFYDLTWA
YLLRCKAQNVVHTEPFFDPQTHTDRGIPFEVVLAGITGALKDGKSKLGVDSGLILSFLRHLSQEEAEKTLDQALPFRDAF
VAVGLDSSEMGHPPSKFQRVFDRARNEGFLTVAHAGEEGPPEYIWEALDLLKIQRIDHGVRAIEDERLMQRIIDEQIPLT
VCPLSNTKLCVFDDMAQHNILDMLERGVKVTVNSDDPAYFGGYVTENFHALYTHLGMTEDQAKRLAQNSLDARLVKP

Sequences:

>Translated_317_residues
MYDWLNALPKAELHLHLEGSLEPELLFALAERNRIALPWDDVETLRKAYAFNNLQEFLDLYYRGADVLRTEQDFYDLTWA
YLLRCKAQNVVHTEPFFDPQTHTDRGIPFEVVLAGITGALKDGKSKLGVDSGLILSFLRHLSQEEAEKTLDQALPFRDAF
VAVGLDSSEMGHPPSKFQRVFDRARNEGFLTVAHAGEEGPPEYIWEALDLLKIQRIDHGVRAIEDERLMQRIIDEQIPLT
VCPLSNTKLCVFDDMAQHNILDMLERGVKVTVNSDDPAYFGGYVTENFHALYTHLGMTEDQAKRLAQNSLDARLVKP
>Mature_317_residues
MYDWLNALPKAELHLHLEGSLEPELLFALAERNRIALPWDDVETLRKAYAFNNLQEFLDLYYRGADVLRTEQDFYDLTWA
YLLRCKAQNVVHTEPFFDPQTHTDRGIPFEVVLAGITGALKDGKSKLGVDSGLILSFLRHLSQEEAEKTLDQALPFRDAF
VAVGLDSSEMGHPPSKFQRVFDRARNEGFLTVAHAGEEGPPEYIWEALDLLKIQRIDHGVRAIEDERLMQRIIDEQIPLT
VCPLSNTKLCVFDDMAQHNILDMLERGVKVTVNSDDPAYFGGYVTENFHALYTHLGMTEDQAKRLAQNSLDARLVKP

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=329, Percent_Identity=25.2279635258359, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI1787910, Length=311, Percent_Identity=27.9742765273312, Blast_Score=139, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32565969, Length=318, Percent_Identity=26.1006289308176, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538512, Length=318, Percent_Identity=26.1006289308176, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324188, Length=294, Percent_Identity=47.2789115646259, Blast_Score=265, Evalue=6e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 36114; Mature: 36114

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDWLNALPKAELHLHLEGSLEPELLFALAERNRIALPWDDVETLRKAYAFNNLQEFLDL
CCCHHHHCCCCEEEEEECCCCCHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHH
YYRGADVLRTEQDFYDLTWAYLLRCKAQNVVHTEPFFDPQTHTDRGIPFEVVLAGITGAL
HHCCCHHHHCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
KDGKSKLGVDSGLILSFLRHLSQEEAEKTLDQALPFRDAFVAVGLDSSEMGHPPSKFQRV
HCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCCCCHHHHHHH
FDRARNEGFLTVAHAGEEGPPEYIWEALDLLKIQRIDHGVRAIEDERLMQRIIDEQIPLT
HHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VCPLSNTKLCVFDDMAQHNILDMLERGVKVTVNSDDPAYFGGYVTENFHALYTHLGMTED
EECCCCCEEEEECCHHHHHHHHHHHCCCEEEECCCCCCEECCHHHHHHHHHHHHCCCCHH
QAKRLAQNSLDARLVKP
HHHHHHHHCCCCEECCC
>Mature Secondary Structure
MYDWLNALPKAELHLHLEGSLEPELLFALAERNRIALPWDDVETLRKAYAFNNLQEFLDL
CCCHHHHCCCCEEEEEECCCCCHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHH
YYRGADVLRTEQDFYDLTWAYLLRCKAQNVVHTEPFFDPQTHTDRGIPFEVVLAGITGAL
HHCCCHHHHCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
KDGKSKLGVDSGLILSFLRHLSQEEAEKTLDQALPFRDAFVAVGLDSSEMGHPPSKFQRV
HCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCCCCHHHHHHH
FDRARNEGFLTVAHAGEEGPPEYIWEALDLLKIQRIDHGVRAIEDERLMQRIIDEQIPLT
HHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VCPLSNTKLCVFDDMAQHNILDMLERGVKVTVNSDDPAYFGGYVTENFHALYTHLGMTED
EECCCCCEEEEECCHHHHHHHHHHHCCCEEEECCCCCCEECCHHHHHHHHHHHHCCCCHH
QAKRLAQNSLDARLVKP
HHHHHHHHCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA