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The map label for this gene is mauR [H]

Identifier: 66043718

GI number: 66043718

Start: 486927

End: 487853

Strand: Reverse

Name: mauR [H]

Synonym: Psyr_0451

Alternate gene names: 66043718

Gene position: 487853-486927 (Counterclockwise)

Preceding gene: 66043720

Following gene: 66043708

Centisome position: 8.01

GC content: 60.3

Gene sequence:

>927_bases
ATGCAGATCGATGACGAACTGACGCTCAAGAAACTGGAAATATTCCTGGCCTTCATGCGCACCGGCAATCTGGCGCGGGC
GGCGGAGGAGTTGCAGACCAGTAACGTCAGCGTGCACCGCGCCATTCATTCGCTGGAAAGCGCGCTGCGTTGCCCGCTGT
TCAAGCACGAGGGACGCAACCTGACGCCACTGGAAAGCGCGTATGTGCTGGAAGAACGTGCACAGAAACTGGTCCAGGAT
GTGCTCGCCACGGTGGAACTGACCCGTCAGGCAGCAGGCTTCTCGGCGGCGCGGTTCAGGCTGGGGGCGTTGTACTCGCT
GACCGTCAAGACGGTGCCGCAGCTGATCATGGGCCTGAAGATCCGCCGCAGCGAGCTGAATATCGACCTGATTCTGGGCT
CGAACATGGACCTGCTCTACAAGCTCAAGAACATGGAAGTCGATGCGATGCTGGTGTCGCTGGATGAAAGCACCCATGAC
CCGGACTGCGAGCATCTGGCGCTGTTTTCCGACGACATCTTTCTCGCCGTCCCCACCGACTCACCGTTCGCCGAACACCC
TGAAGTGGACCTGAGCGACCTGCGCGAAGCGACGTTCATCACCCTGACCCAAGGCTTCGCCACGCACCGCGACGGGATCC
GCGTATTCCAGCAGGCCGGTTTCGAGCCCAAGGTGGCGATGCAGGTCAATGACATCTTCACCCTGCTGAGCATGGTCAGC
TCCGGCGTCGGCTATGCACTGCTGCCGGGAAGAATCGCCGCGGTCTATGAAAACCGCGTGCGCCTGATCCCGTTGCAGAG
CCGCTACCGGATGCAACAACACATCGGCATTGTTTTTCTCAAGTCCAAACAGCGCGATCCCAACCTGCTGGCGCTGTTGG
CCGAGTGCCGGATGTACACCAACCGGCTGCTGGAACAGACGACCTGA

Upstream 100 bases:

>100_bases
GAAAATACTGATGACAGACGCTCCCGGTTATTGAAACAAAGAGCAACGTATCTGTCATTACAGGGCACAATCAGCGCACC
TTAACCATAAGCGCCACGAC

Downstream 100 bases:

>100_bases
CCTAGCCGACGATGGCGCGCACGATGAAGTACAGCACCGATGGCCCGAGCAGACAGCCCAGACCGGTGTGGAACGTGGCG
GTCAGCGCGCCATAAGGCAC

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MQIDDELTLKKLEIFLAFMRTGNLARAAEELQTSNVSVHRAIHSLESALRCPLFKHEGRNLTPLESAYVLEERAQKLVQD
VLATVELTRQAAGFSAARFRLGALYSLTVKTVPQLIMGLKIRRSELNIDLILGSNMDLLYKLKNMEVDAMLVSLDESTHD
PDCEHLALFSDDIFLAVPTDSPFAEHPEVDLSDLREATFITLTQGFATHRDGIRVFQQAGFEPKVAMQVNDIFTLLSMVS
SGVGYALLPGRIAAVYENRVRLIPLQSRYRMQQHIGIVFLKSKQRDPNLLALLAECRMYTNRLLEQTT

Sequences:

>Translated_308_residues
MQIDDELTLKKLEIFLAFMRTGNLARAAEELQTSNVSVHRAIHSLESALRCPLFKHEGRNLTPLESAYVLEERAQKLVQD
VLATVELTRQAAGFSAARFRLGALYSLTVKTVPQLIMGLKIRRSELNIDLILGSNMDLLYKLKNMEVDAMLVSLDESTHD
PDCEHLALFSDDIFLAVPTDSPFAEHPEVDLSDLREATFITLTQGFATHRDGIRVFQQAGFEPKVAMQVNDIFTLLSMVS
SGVGYALLPGRIAAVYENRVRLIPLQSRYRMQQHIGIVFLKSKQRDPNLLALLAECRMYTNRLLEQTT
>Mature_308_residues
MQIDDELTLKKLEIFLAFMRTGNLARAAEELQTSNVSVHRAIHSLESALRCPLFKHEGRNLTPLESAYVLEERAQKLVQD
VLATVELTRQAAGFSAARFRLGALYSLTVKTVPQLIMGLKIRRSELNIDLILGSNMDLLYKLKNMEVDAMLVSLDESTHD
PDCEHLALFSDDIFLAVPTDSPFAEHPEVDLSDLREATFITLTQGFATHRDGIRVFQQAGFEPKVAMQVNDIFTLLSMVS
SGVGYALLPGRIAAVYENRVRLIPLQSRYRMQQHIGIVFLKSKQRDPNLLALLAECRMYTNRLLEQTT

Specific function: Transcriptional regulator of the mau genes for malonate utilization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=249, Percent_Identity=24.4979919678715, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788887, Length=252, Percent_Identity=23.4126984126984, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI2367136, Length=292, Percent_Identity=27.3972602739726, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787879, Length=296, Percent_Identity=21.9594594594595, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34719; Mature: 34719

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIDDELTLKKLEIFLAFMRTGNLARAAEELQTSNVSVHRAIHSLESALRCPLFKHEGRN
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHCCCCC
LTPLESAYVLEERAQKLVQDVLATVELTRQAAGFSAARFRLGALYSLTVKTVPQLIMGLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCE
IRRSELNIDLILGSNMDLLYKLKNMEVDAMLVSLDESTHDPDCEHLALFSDDIFLAVPTD
EEECCCCEEEEECCCCCEEEEECCCCEEEEEEEECCCCCCCCCCEEEEECCCEEEEECCC
SPFAEHPEVDLSDLREATFITLTQGFATHRDGIRVFQQAGFEPKVAMQVNDIFTLLSMVS
CCCCCCCCCCHHHHCHHEEEEEECCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHH
SGVGYALLPGRIAAVYENRVRLIPLQSRYRMQQHIGIVFLKSKQRDPNLLALLAECRMYT
CCCCEEECCCHHEEEECCCEEEEECHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHH
NRLLEQTT
HHHHHCCC
>Mature Secondary Structure
MQIDDELTLKKLEIFLAFMRTGNLARAAEELQTSNVSVHRAIHSLESALRCPLFKHEGRN
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHCCCCC
LTPLESAYVLEERAQKLVQDVLATVELTRQAAGFSAARFRLGALYSLTVKTVPQLIMGLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCE
IRRSELNIDLILGSNMDLLYKLKNMEVDAMLVSLDESTHDPDCEHLALFSDDIFLAVPTD
EEECCCCEEEEECCCCCEEEEECCCCEEEEEEEECCCCCCCCCCEEEEECCCEEEEECCC
SPFAEHPEVDLSDLREATFITLTQGFATHRDGIRVFQQAGFEPKVAMQVNDIFTLLSMVS
CCCCCCCCCCHHHHCHHEEEEEECCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHH
SGVGYALLPGRIAAVYENRVRLIPLQSRYRMQQHIGIVFLKSKQRDPNLLALLAECRMYT
CCCCEEECCCHHEEEECCCEEEEECHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHH
NRLLEQTT
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA