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The map label for this gene is ubiH [H]

Identifier: 66043591

GI number: 66043591

Start: 338837

End: 340024

Strand: Direct

Name: ubiH [H]

Synonym: Psyr_0322

Alternate gene names: 66043591

Gene position: 338837-340024 (Clockwise)

Preceding gene: 66043590

Following gene: 66043592

Centisome position: 5.56

GC content: 65.24

Gene sequence:

>1188_bases
ATGAGCCGCTTCAATATCGCCATCGTCGGCGGCGGATTGGTCGGTGCGAGCCTTGCGCTGTCGCTGCAGGCCGGTGCCAA
GGCGCGCGGCTGGAAAATCGTGCTCATCGAGCCCTTCGCGCCGGGTGAAGCCTGGCAGCCCAGCTACGATGCGCGTTCTT
CGGCACTGTCGTTCGGCTCGCGACGCATCTATGAACGGCTTGGCCTCTGGCAGCAGATTTCCCGACGCGCCGAGCCGATC
CTGCAAATCCAGGTGTCGGACCGGGGTCGCTTCGGCGCCACTCGCCTGTCGGCGATCGAAGAGGGCGTTCCGGCGCTTGG
CTATGTAGTCGAAAACGCCTGGCTCGGTCAGGCTCTGTGGGCCGGGCTGGACCGTGATGTGGTCAGTTGGCGTGTGCCGG
CCGAGGTCAAACACATGCAGCCATTGGCCGATGGTTATCGCCTGAGCCTCAGTGACGACAGCGAACTGGACTGCGACCTG
GCCGTGCTGGCCGACGGTGGCCGTTCCAGTCTGCGCGAACAGTTGGGTATCGGGGTGCGGCAACGGCCTTACGACCAGCA
TGCGCTGATTGCCAATATCACGCCGAGCGAAGCTCACTGCGGGCAGGCGTTTGAACGTTTTACCGAAGACGGGCCGATGG
CGCTGCTGCCATTGCCGGATAACCGCTGTGCGTTGGTCTGGACACGTCCGGGCAACGATACCCAGCGTCTGGCCGAGCTG
GACGACCGCAGTTTTCTGGAAGAGCTGCAGGGCGTGTTTGGCTATCGCCTGGGCACGCTGCGTCAGGTAGGTGCCCGGCA
TGTCTACCCCTTGGCACTGATCGAAGCCGAAGAGCAGGTGCGCTCGCATCTGGTGATCCTGGGCAACGCGGCGCACAGTC
TGCATCCGGTCGCCGGGCAGGGGTTCAATCTGTCCTTGCGCGACGCCGATGCACTGGCCGAGACGCTGCTGGACAGCGAC
GCGCCGCCCGGTGCGCTGCCGACGCTGCAGCTCTACCGTGAGCGCCAGCGCCAGGATCAGCAATTGACCGTGGGCTTTTC
CGACAAGGTGACGCGCCTGTTCGGCAGCTCCCGGTCGGCGGTTGCCACCGGGCGTAACGTCGGGTTGCTCGGCCTGGACC
TGCTGCCTGCCGCCAAGCGCTGGTTTGCCCGCCAGGCCATGGGGTTGGGGACTCGATCCGATGTGTGA

Upstream 100 bases:

>100_bases
TGGTTGTGACCAGGCAGGGGTGTGAAATTCTGTCCGGCGGCGTGCCCAAGACCGTCGCCGAGATCGAGGCGCTGATGGCG
GCTGCACAGGAACAGGTCGT

Downstream 100 bases:

>100_bases
ATCACCCACTTTAAACACAGGGCTTCGGCCGCAAGCGAGAACGGTTTGACCATGGAAACGCGCGCAGATGTGCTGATTGT
CGGAGCCGGAATGGTCGGCA

Product: 2-octaprenyl-6-methoxyphenyl hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MSRFNIAIVGGGLVGASLALSLQAGAKARGWKIVLIEPFAPGEAWQPSYDARSSALSFGSRRIYERLGLWQQISRRAEPI
LQIQVSDRGRFGATRLSAIEEGVPALGYVVENAWLGQALWAGLDRDVVSWRVPAEVKHMQPLADGYRLSLSDDSELDCDL
AVLADGGRSSLREQLGIGVRQRPYDQHALIANITPSEAHCGQAFERFTEDGPMALLPLPDNRCALVWTRPGNDTQRLAEL
DDRSFLEELQGVFGYRLGTLRQVGARHVYPLALIEAEEQVRSHLVILGNAAHSLHPVAGQGFNLSLRDADALAETLLDSD
APPGALPTLQLYRERQRQDQQLTVGFSDKVTRLFGSSRSAVATGRNVGLLGLDLLPAAKRWFARQAMGLGTRSDV

Sequences:

>Translated_395_residues
MSRFNIAIVGGGLVGASLALSLQAGAKARGWKIVLIEPFAPGEAWQPSYDARSSALSFGSRRIYERLGLWQQISRRAEPI
LQIQVSDRGRFGATRLSAIEEGVPALGYVVENAWLGQALWAGLDRDVVSWRVPAEVKHMQPLADGYRLSLSDDSELDCDL
AVLADGGRSSLREQLGIGVRQRPYDQHALIANITPSEAHCGQAFERFTEDGPMALLPLPDNRCALVWTRPGNDTQRLAEL
DDRSFLEELQGVFGYRLGTLRQVGARHVYPLALIEAEEQVRSHLVILGNAAHSLHPVAGQGFNLSLRDADALAETLLDSD
APPGALPTLQLYRERQRQDQQLTVGFSDKVTRLFGSSRSAVATGRNVGLLGLDLLPAAKRWFARQAMGLGTRSDV
>Mature_394_residues
SRFNIAIVGGGLVGASLALSLQAGAKARGWKIVLIEPFAPGEAWQPSYDARSSALSFGSRRIYERLGLWQQISRRAEPIL
QIQVSDRGRFGATRLSAIEEGVPALGYVVENAWLGQALWAGLDRDVVSWRVPAEVKHMQPLADGYRLSLSDDSELDCDLA
VLADGGRSSLREQLGIGVRQRPYDQHALIANITPSEAHCGQAFERFTEDGPMALLPLPDNRCALVWTRPGNDTQRLAELD
DRSFLEELQGVFGYRLGTLRQVGARHVYPLALIEAEEQVRSHLVILGNAAHSLHPVAGQGFNLSLRDADALAETLLDSDA
PPGALPTLQLYRERQRQDQQLTVGFSDKVTRLFGSSRSAVATGRNVGLLGLDLLPAAKRWFARQAMGLGTRSDV

Specific function: Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=406, Percent_Identity=29.064039408867, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI32967307, Length=319, Percent_Identity=30.0940438871473, Blast_Score=112, Evalue=5e-25,
Organism=Escherichia coli, GI1789274, Length=389, Percent_Identity=37.7892030848329, Blast_Score=261, Evalue=5e-71,
Organism=Escherichia coli, GI1789273, Length=397, Percent_Identity=32.7455919395466, Blast_Score=175, Evalue=6e-45,
Organism=Escherichia coli, GI1786883, Length=390, Percent_Identity=31.7948717948718, Blast_Score=162, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI25146631, Length=436, Percent_Identity=26.8348623853211, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI19920760, Length=447, Percent_Identity=26.1744966442953, Blast_Score=122, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971
- InterPro:   IPR011295 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 43163; Mature: 43032

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFNIAIVGGGLVGASLALSLQAGAKARGWKIVLIEPFAPGEAWQPSYDARSSALSFGS
CCCEEEEEEECCHHHHHHEEEECCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
RRIYERLGLWQQISRRAEPILQIQVSDRGRFGATRLSAIEEGVPALGYVVENAWLGQALW
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AGLDRDVVSWRVPAEVKHMQPLADGYRLSLSDDSELDCDLAVLADGGRSSLREQLGIGVR
CCCCCCHHEEECCHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHCCCCC
QRPYDQHALIANITPSEAHCGQAFERFTEDGPMALLPLPDNRCALVWTRPGNDTQRLAEL
CCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHC
DDRSFLEELQGVFGYRLGTLRQVGARHVYPLALIEAEEQVRSHLVILGNAAHSLHPVAGQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHCEEEEEECCCCCCCCCCCC
GFNLSLRDADALAETLLDSDAPPGALPTLQLYRERQRQDQQLTVGFSDKVTRLFGSSRSA
CCEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCC
VATGRNVGLLGLDLLPAAKRWFARQAMGLGTRSDV
EECCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SRFNIAIVGGGLVGASLALSLQAGAKARGWKIVLIEPFAPGEAWQPSYDARSSALSFGS
CCEEEEEEECCHHHHHHEEEECCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
RRIYERLGLWQQISRRAEPILQIQVSDRGRFGATRLSAIEEGVPALGYVVENAWLGQALW
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AGLDRDVVSWRVPAEVKHMQPLADGYRLSLSDDSELDCDLAVLADGGRSSLREQLGIGVR
CCCCCCHHEEECCHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHCCCCC
QRPYDQHALIANITPSEAHCGQAFERFTEDGPMALLPLPDNRCALVWTRPGNDTQRLAEL
CCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHC
DDRSFLEELQGVFGYRLGTLRQVGARHVYPLALIEAEEQVRSHLVILGNAAHSLHPVAGQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHCEEEEEECCCCCCCCCCCC
GFNLSLRDADALAETLLDSDAPPGALPTLQLYRERQRQDQQLTVGFSDKVTRLFGSSRSA
CCEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCC
VATGRNVGLLGLDLLPAAKRWFARQAMGLGTRSDV
EECCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]