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The map label for this gene is argE [H]

Identifier: 66043523

GI number: 66043523

Start: 266353

End: 267540

Strand: Direct

Name: argE [H]

Synonym: Psyr_0253

Alternate gene names: 66043523

Gene position: 266353-267540 (Clockwise)

Preceding gene: 66043521

Following gene: 66043524

Centisome position: 4.37

GC content: 63.89

Gene sequence:

>1188_bases
ATGATGGGCCGTGTTCCGTCTCGATTACAGGAAGCGTCCATGCCGTTGCCGTCCATGAAAGACCAGTTCGCCGCGCTGAT
CGCCGTACCCTCGGTGAGCTGCACTCAGCCTTCCCTGGACCAGAGCAACCGCCCCGTCATCGATCTGCTGGCCGGATGGC
TCGGCGATCTGGGGTTTGCCTGCGACATCCAGCAAGTTTCCCCCGGCAAGTTCAATCTGCTGGCGACCTACGGTACAGGC
CCGGGCGGCCTGGTACTGGCGGGGCACAGCGATACCGTGCCGTTCGACGAGGCACTGTGGAAAACCGACCCCTTGAAGCT
GACCGAGGTGGATGGCCGCTGGGTCGGGCTGGGCAGTTGTGACATGAAGGGCTTCTTTGCGCTGGTCATCGAAGCGGTGC
GTGGCCTTCTTGACCAGCCGTTCAAGCAGCCGCTGCTGATCCTCGCCACCTGCGACGAGGAAAGCTCGATGGCCGGTGCC
CGCGCGCTGGCCGACGCCGGACGCCCGCTGGGTCGTGCGGCAGTGATTGGCGAGCCGACCGGGCTCAAGCCGATCCGCCT
GCATAAGGGCGTGATGATGGAGCGCATCGATATTCTCGGGCGCAGCGGTCATTCCTCCGACCCGAGCCTCGGGCACAGCG
CACTCGAAGCCATGCACGACGCCATCAGCGAACTCAAGGGCCTGCGCACGCAGTGGCAGGCGAAGTACCGCAACCCGCAA
TTCACGGTGCCGCAGCCGACGCTGAACCTGGGCTGTATTCATGGCGGCGACAACCCGAACCGGATTTGTGGCCAGTGCTC
GCTGGAGTTCGACCTGCGTCCGCTGCCGGGCATGGACCCGGAGATGCTGCGCTCGGCGATTCGGCAGAAGCTGCAGCCGC
TGGCCGAGCTGCACCAGGTACAGATCGACTACGCACCGCTGTTCCCCGAATGTGCGCCGTTCGAGCAGATCGCTGACGCT
GAACTTGTGCGTGTCGCTGAACGTCTGACCGGTCATACCGCTGCCGCAGTAGCATTCGGCACCGAAGCGCCTTATCTTCA
GCGCCTCGGCTGCGAGACACTGGTGCTCGGCCCGGGCGACATCGCCTGTGCGCATCAGCCGGGGGAATACCTCGAAATGT
CACGTCTTGACCCTACAGTGCGTCTGTTACGTCAACTGATCGAACATTACTGCCTGACGCCCCAGTGA

Upstream 100 bases:

>100_bases
ACGGATAAACGGGAGCGCAGCCCATGATTGAACGGCTGCTGAGGCCGTCAGTGTACAGGACATGGCCCGAAACGGTTTAT
TCCTGGGTTGCTATGGCCCT

Downstream 100 bases:

>100_bases
GTCAGGCATACCCCGTGTTTGTTAATCAAAGCATCTTGAGTAAAAGGAGACTGCGCGTGCTGCCAAGCCTGTTCCGACGA
TAACCACCACACCGTTGTGC

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MMGRVPSRLQEASMPLPSMKDQFAALIAVPSVSCTQPSLDQSNRPVIDLLAGWLGDLGFACDIQQVSPGKFNLLATYGTG
PGGLVLAGHSDTVPFDEALWKTDPLKLTEVDGRWVGLGSCDMKGFFALVIEAVRGLLDQPFKQPLLILATCDEESSMAGA
RALADAGRPLGRAAVIGEPTGLKPIRLHKGVMMERIDILGRSGHSSDPSLGHSALEAMHDAISELKGLRTQWQAKYRNPQ
FTVPQPTLNLGCIHGGDNPNRICGQCSLEFDLRPLPGMDPEMLRSAIRQKLQPLAELHQVQIDYAPLFPECAPFEQIADA
ELVRVAERLTGHTAAAVAFGTEAPYLQRLGCETLVLGPGDIACAHQPGEYLEMSRLDPTVRLLRQLIEHYCLTPQ

Sequences:

>Translated_395_residues
MMGRVPSRLQEASMPLPSMKDQFAALIAVPSVSCTQPSLDQSNRPVIDLLAGWLGDLGFACDIQQVSPGKFNLLATYGTG
PGGLVLAGHSDTVPFDEALWKTDPLKLTEVDGRWVGLGSCDMKGFFALVIEAVRGLLDQPFKQPLLILATCDEESSMAGA
RALADAGRPLGRAAVIGEPTGLKPIRLHKGVMMERIDILGRSGHSSDPSLGHSALEAMHDAISELKGLRTQWQAKYRNPQ
FTVPQPTLNLGCIHGGDNPNRICGQCSLEFDLRPLPGMDPEMLRSAIRQKLQPLAELHQVQIDYAPLFPECAPFEQIADA
ELVRVAERLTGHTAAAVAFGTEAPYLQRLGCETLVLGPGDIACAHQPGEYLEMSRLDPTVRLLRQLIEHYCLTPQ
>Mature_395_residues
MMGRVPSRLQEASMPLPSMKDQFAALIAVPSVSCTQPSLDQSNRPVIDLLAGWLGDLGFACDIQQVSPGKFNLLATYGTG
PGGLVLAGHSDTVPFDEALWKTDPLKLTEVDGRWVGLGSCDMKGFFALVIEAVRGLLDQPFKQPLLILATCDEESSMAGA
RALADAGRPLGRAAVIGEPTGLKPIRLHKGVMMERIDILGRSGHSSDPSLGHSALEAMHDAISELKGLRTQWQAKYRNPQ
FTVPQPTLNLGCIHGGDNPNRICGQCSLEFDLRPLPGMDPEMLRSAIRQKLQPLAELHQVQIDYAPLFPECAPFEQIADA
ELVRVAERLTGHTAAAVAFGTEAPYLQRLGCETLVLGPGDIACAHQPGEYLEMSRLDPTVRLLRQLIEHYCLTPQ

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=378, Percent_Identity=49.7354497354497, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1788816, Length=389, Percent_Identity=24.9357326478149, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42825; Mature: 42825

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGRVPSRLQEASMPLPSMKDQFAALIAVPSVSCTQPSLDQSNRPVIDLLAGWLGDLGFA
CCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCE
CDIQQVSPGKFNLLATYGTGPGGLVLAGHSDTVPFDEALWKTDPLKLTEVDGRWVGLGSC
EECCCCCCCCEEEEEEECCCCCCEEEECCCCCCCHHHHHCCCCCEEEEECCCCEEECCCC
DMKGFFALVIEAVRGLLDQPFKQPLLILATCDEESSMAGARALADAGRPLGRAAVIGEPT
CHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEECCCC
GLKPIRLHKGVMMERIDILGRSGHSSDPSLGHSALEAMHDAISELKGLRTQWQAKYRNPQ
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FTVPQPTLNLGCIHGGDNPNRICGQCSLEFDLRPLPGMDPEMLRSAIRQKLQPLAELHQV
EECCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHE
QIDYAPLFPECAPFEQIADAELVRVAERLTGHTAAAVAFGTEAPYLQRLGCETLVLGPGD
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEEEECCCCHHHHHCCCCEEEECCCC
IACAHQPGEYLEMSRLDPTVRLLRQLIEHYCLTPQ
EEECCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMGRVPSRLQEASMPLPSMKDQFAALIAVPSVSCTQPSLDQSNRPVIDLLAGWLGDLGFA
CCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCE
CDIQQVSPGKFNLLATYGTGPGGLVLAGHSDTVPFDEALWKTDPLKLTEVDGRWVGLGSC
EECCCCCCCCEEEEEEECCCCCCEEEECCCCCCCHHHHHCCCCCEEEEECCCCEEECCCC
DMKGFFALVIEAVRGLLDQPFKQPLLILATCDEESSMAGARALADAGRPLGRAAVIGEPT
CHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEECCCC
GLKPIRLHKGVMMERIDILGRSGHSSDPSLGHSALEAMHDAISELKGLRTQWQAKYRNPQ
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FTVPQPTLNLGCIHGGDNPNRICGQCSLEFDLRPLPGMDPEMLRSAIRQKLQPLAELHQV
EECCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHE
QIDYAPLFPECAPFEQIADAELVRVAERLTGHTAAAVAFGTEAPYLQRLGCETLVLGPGD
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEEEECCCCHHHHHCCCCEEEECCCC
IACAHQPGEYLEMSRLDPTVRLLRQLIEHYCLTPQ
EEECCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10692366 [H]