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The map label for this gene is argA [H]

Identifier: 66043524

GI number: 66043524

Start: 267685

End: 268983

Strand: Direct

Name: argA [H]

Synonym: Psyr_0254

Alternate gene names: 66043524

Gene position: 267685-268983 (Clockwise)

Preceding gene: 66043523

Following gene: 66043528

Centisome position: 4.39

GC content: 64.05

Gene sequence:

>1299_bases
ATGCCCGAATACGTCAACTGGCTTCGCCACGCGTCTCCGTACATCAATGCTCACCGCGATTGCACCTTCGTCGTCATGCT
GCCCGGCGACGGCGTTGCGCACCCCAATTTCGGCAATATCGTCCACGATCTGGTGCTGCTGCACAGCCTGGGCGTGCGTC
TGGTGCTGGTTCACGGTTCCCGTCCGCAGATCGAGAGCCGCCTGGCCCAGCGCGGGATTACGCCGCGTTACCACCGTGAC
CTGCGGATCACTGACACCGAAACGCTGGAGTGCGTGATCGATGCCGTGGGTCAGCTGCGCATCTCGATCGAGGCGCGTCT
GTCGATGGACATGGCCGCCTCGCCCATGCAGGGCTCGCGCTTGCGAGTGACCAGCGGCAATGTCGTCACCGCACGGCCTA
TCGGCGTGCTTGAGGGGGTCGATTATCAGCACACCGGCGAAGTGCGCCGCGTCGACCGCAAGGGTATCAATCGCCTGCTG
GACGAGCGCCATATCGTGCTGCTGTCGCCACTGGGTTATTCGCCGACCGGCGAGATTTTCAACCTGGCCTGTGAAGACGT
CGCCACCCGCGCGGCCATCGATCTGGCTGCTGACAAACTGCTGCTGTTCGGCGCCGAAACCGGCTTGCTGGACGAGCAGG
GCCGGTTGGTGCGCGAACTGCGTCCGCAACAGGTGCCCGCGCACCTGCAGCGTCTGGGTGCCAACTATCAGGCGGAATTG
CTGGACGCTGCGGCCGAGGCCTGCCGTGGCGGTGTGGCGCGCAGCCATATCGTCAGTTATGCCGAGAACGGCGCGCTGCT
CACCGAGCTGTTTACCCGTGACGGCGGCGGCACGCTGGTCGCGCAGGAGCAGTTCGAGCTGGTGCGTGAAGCGGCCATCG
AGGATGTCGGCGGTTTGATGGACCTGATCACGCCGCTGGAAGAGCAGGGCATTCTGGTGCGTCGTTCCCGCGAGGTGCTG
GAGCGCGAGATCACCCAGTTCAGCGTTGTCGAGCGCGAAGGGCTGATCATCGCCTGCGCTGCGCTGTATCCGATTGCCGA
TTCGGAGTCGGGCGAGCTGGCGTGTCTGGCGGTCAACCCGGAATACCGGCACGGTGGCCGTGGCGATGAACTGCTGGAGC
GCATTGAAAACCGCGCCCGGGCTTTGGGTATCAAGACCCTGTTCGTCCTCACCACCCGCACCGCACACTGGTTCCGCGAG
CGCGGTTTCGAACCCAGCAGCGTCGACCGCCTGCCAAGCGCTCGCGCCTCGCTGTACAACTACCAGCGTAATTCGAAGAT
CTTCGAAAAGGCGATATAA

Upstream 100 bases:

>100_bases
AGGAGACTGCGCGTGCTGCCAAGCCTGTTCCGACGATAACCACCACACCGTTGTGCGTGCTTCTTTTCTTCGTCCATTTT
TTCTACAGGCTCTTGTTGTC

Downstream 100 bases:

>100_bases
GCCTGGGGGCGGACTATATTTTGTGGGAGTGAGCTTGCTCACGAAGAGGCTGGAACAAGCCTCCAGAAAGGGGCGTTTGA
ACCGTCCCTTTCGTGAGCAA

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MPEYVNWLRHASPYINAHRDCTFVVMLPGDGVAHPNFGNIVHDLVLLHSLGVRLVLVHGSRPQIESRLAQRGITPRYHRD
LRITDTETLECVIDAVGQLRISIEARLSMDMAASPMQGSRLRVTSGNVVTARPIGVLEGVDYQHTGEVRRVDRKGINRLL
DERHIVLLSPLGYSPTGEIFNLACEDVATRAAIDLAADKLLLFGAETGLLDEQGRLVRELRPQQVPAHLQRLGANYQAEL
LDAAAEACRGGVARSHIVSYAENGALLTELFTRDGGGTLVAQEQFELVREAAIEDVGGLMDLITPLEEQGILVRRSREVL
EREITQFSVVEREGLIIACAALYPIADSESGELACLAVNPEYRHGGRGDELLERIENRARALGIKTLFVLTTRTAHWFRE
RGFEPSSVDRLPSARASLYNYQRNSKIFEKAI

Sequences:

>Translated_432_residues
MPEYVNWLRHASPYINAHRDCTFVVMLPGDGVAHPNFGNIVHDLVLLHSLGVRLVLVHGSRPQIESRLAQRGITPRYHRD
LRITDTETLECVIDAVGQLRISIEARLSMDMAASPMQGSRLRVTSGNVVTARPIGVLEGVDYQHTGEVRRVDRKGINRLL
DERHIVLLSPLGYSPTGEIFNLACEDVATRAAIDLAADKLLLFGAETGLLDEQGRLVRELRPQQVPAHLQRLGANYQAEL
LDAAAEACRGGVARSHIVSYAENGALLTELFTRDGGGTLVAQEQFELVREAAIEDVGGLMDLITPLEEQGILVRRSREVL
EREITQFSVVEREGLIIACAALYPIADSESGELACLAVNPEYRHGGRGDELLERIENRARALGIKTLFVLTTRTAHWFRE
RGFEPSSVDRLPSARASLYNYQRNSKIFEKAI
>Mature_431_residues
PEYVNWLRHASPYINAHRDCTFVVMLPGDGVAHPNFGNIVHDLVLLHSLGVRLVLVHGSRPQIESRLAQRGITPRYHRDL
RITDTETLECVIDAVGQLRISIEARLSMDMAASPMQGSRLRVTSGNVVTARPIGVLEGVDYQHTGEVRRVDRKGINRLLD
ERHIVLLSPLGYSPTGEIFNLACEDVATRAAIDLAADKLLLFGAETGLLDEQGRLVRELRPQQVPAHLQRLGANYQAELL
DAAAEACRGGVARSHIVSYAENGALLTELFTRDGGGTLVAQEQFELVREAAIEDVGGLMDLITPLEEQGILVRRSREVLE
REITQFSVVEREGLIIACAALYPIADSESGELACLAVNPEYRHGGRGDELLERIENRARALGIKTLFVLTTRTAHWFRER
GFEPSSVDRLPSARASLYNYQRNSKIFEKAI

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=431, Percent_Identity=50.1160092807425, Blast_Score=450, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6320913, Length=290, Percent_Identity=23.448275862069, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 47916; Mature: 47785

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEYVNWLRHASPYINAHRDCTFVVMLPGDGVAHPNFGNIVHDLVLLHSLGVRLVLVHGS
CCHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECC
RPQIESRLAQRGITPRYHRDLRITDTETLECVIDAVGQLRISIEARLSMDMAASPMQGSR
CCHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCE
LRVTSGNVVTARPIGVLEGVDYQHTGEVRRVDRKGINRLLDERHIVLLSPLGYSPTGEIF
EEEECCCEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHH
NLACEDVATRAAIDLAADKLLLFGAETGLLDEQGRLVRELRPQQVPAHLQRLGANYQAEL
HHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCHHHHH
LDAAAEACRGGVARSHIVSYAENGALLTELFTRDGGGTLVAQEQFELVREAAIEDVGGLM
HHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHH
DLITPLEEQGILVRRSREVLEREITQFSVVEREGLIIACAALYPIADSESGELACLAVNP
HHHCCHHHCCEEHHHHHHHHHHHHHHHHHEECCCEEEEEEECCCCCCCCCCCEEEEEECC
EYRHGGRGDELLERIENRARALGIKTLFVLTTRTAHWFRERGFEPSSVDRLPSARASLYN
CCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHCCCCCCHHHHCCHHHHHHHH
YQRNSKIFEKAI
HHHCCHHHHHCC
>Mature Secondary Structure 
PEYVNWLRHASPYINAHRDCTFVVMLPGDGVAHPNFGNIVHDLVLLHSLGVRLVLVHGS
CHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECC
RPQIESRLAQRGITPRYHRDLRITDTETLECVIDAVGQLRISIEARLSMDMAASPMQGSR
CCHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCE
LRVTSGNVVTARPIGVLEGVDYQHTGEVRRVDRKGINRLLDERHIVLLSPLGYSPTGEIF
EEEECCCEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHH
NLACEDVATRAAIDLAADKLLLFGAETGLLDEQGRLVRELRPQQVPAHLQRLGANYQAEL
HHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCHHHHH
LDAAAEACRGGVARSHIVSYAENGALLTELFTRDGGGTLVAQEQFELVREAAIEDVGGLM
HHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHH
DLITPLEEQGILVRRSREVLEREITQFSVVEREGLIIACAALYPIADSESGELACLAVNP
HHHCCHHHCCEEHHHHHHHHHHHHHHHHHEECCCEEEEEEECCCCCCCCCCCEEEEEECC
EYRHGGRGDELLERIENRARALGIKTLFVLTTRTAHWFRERGFEPSSVDRLPSARASLYN
CCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHCCCCCCHHHHCCHHHHHHHH
YQRNSKIFEKAI
HHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA