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The map label for this gene is ycaK [C]

Identifier: 66043392

GI number: 66043392

Start: 131737

End: 132393

Strand: Direct

Name: ycaK [C]

Synonym: Psyr_0122

Alternate gene names: 66043392

Gene position: 131737-132393 (Clockwise)

Preceding gene: 66043390

Following gene: 66043393

Centisome position: 2.16

GC content: 51.9

Gene sequence:

>657_bases
ATGCACGTCCTCATCGTCACCGCTCATCCAGAGTCACAGTCGCTCACCCATTCCATCGCTGCGAGGGTGGCCAAAGGTAT
CGTACTAGGTGATTCTGCCTCAGTCGTAGAGGTCGCCAACCTCGCGCAAGAAGCATTCAATCCTTGCTTCACTGAGGCTG
ACCTGCAGGTACATCGCCACAAAGCCTCTCCCCCACTTGATGTTCAGCGAGAGCAAGCGCGTATAGAGCGTGCCGATACC
CTCATCCTGGTTTACCCAACTTACTGGTGGTCCATGCCTGCACTTCTCAAGGGTTGGATTGACCGAGTGTTCTCCAATGG
TTGGGCCTTTGATTTCGATCCAGAGGGCTCTCTTACAAAGAAGCTCGGAAAGTTGTCAGTACATTTGATAGGCATAGGCG
GCGCTGATCCGTTGACCTACGAACGCCACGGCTACGGCACTGCTATGAAAACGCAGATGGACCAAGGTATCTTTGGTTAT
TGTGGGGCTGAAGTGCATATTTCGAAGCTATTGCTGAATAGCGAAAACTCAGGTGCCGTTCATGCTCTGGAAATGGCCGA
ACAGTTGGGACGCATTATCAGCAGCGAAGCCTCACCTTCAACGGCAGATACTGAAAGTCTCTATTATCGAGAACATGCCG
GTCCCAACCTCAAATAG

Upstream 100 bases:

>100_bases
GACGTTGACATCTCTATATACCATTAGTAGATTGCGAGCATTACTTACCAAAAGTATATAGTCGGCAACCGCCCGCCTCA
AGGCAACGGAAGGAATCGTA

Downstream 100 bases:

>100_bases
CGCTACTTTGATGTCCGCTTCGGACCGAGAGCAATCCTTAGCCAGTGTTAGCTTTCGCCCCATTACAACCGCTCGCCGAT
GATTACCATTTGACCCCACA

Product: NAD(P)H dehydrogenase (quinone)

Products: NAD+; NADP+; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MHVLIVTAHPESQSLTHSIAARVAKGIVLGDSASVVEVANLAQEAFNPCFTEADLQVHRHKASPPLDVQREQARIERADT
LILVYPTYWWSMPALLKGWIDRVFSNGWAFDFDPEGSLTKKLGKLSVHLIGIGGADPLTYERHGYGTAMKTQMDQGIFGY
CGAEVHISKLLLNSENSGAVHALEMAEQLGRIISSEASPSTADTESLYYREHAGPNLK

Sequences:

>Translated_218_residues
MHVLIVTAHPESQSLTHSIAARVAKGIVLGDSASVVEVANLAQEAFNPCFTEADLQVHRHKASPPLDVQREQARIERADT
LILVYPTYWWSMPALLKGWIDRVFSNGWAFDFDPEGSLTKKLGKLSVHLIGIGGADPLTYERHGYGTAMKTQMDQGIFGY
CGAEVHISKLLLNSENSGAVHALEMAEQLGRIISSEASPSTADTESLYYREHAGPNLK
>Mature_218_residues
MHVLIVTAHPESQSLTHSIAARVAKGIVLGDSASVVEVANLAQEAFNPCFTEADLQVHRHKASPPLDVQREQARIERADT
LILVYPTYWWSMPALLKGWIDRVFSNGWAFDFDPEGSLTKKLGKLSVHLIGIGGADPLTYERHGYGTAMKTQMDQGIFGY
CGAEVHISKLLLNSENSGAVHALEMAEQLGRIISSEASPSTADTESLYYREHAGPNLK

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=228, Percent_Identity=29.8245614035088, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1787129, Length=175, Percent_Identity=29.7142857142857, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.2

Molecular weight: Translated: 23869; Mature: 23869

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVLIVTAHPESQSLTHSIAARVAKGIVLGDSASVVEVANLAQEAFNPCFTEADLQVHRH
CEEEEEEECCCCHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHC
KASPPLDVQREQARIERADTLILVYPTYWWSMPALLKGWIDRVFSNGWAFDFDPEGSLTK
CCCCCCCCCHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHH
KLGKLSVHLIGIGGADPLTYERHGYGTAMKTQMDQGIFGYCGAEVHISKLLLNSENSGAV
HHCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCEEECCCHHEEEHHEECCCCCCCC
HALEMAEQLGRIISSEASPSTADTESLYYREHAGPNLK
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHVLIVTAHPESQSLTHSIAARVAKGIVLGDSASVVEVANLAQEAFNPCFTEADLQVHRH
CEEEEEEECCCCHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHC
KASPPLDVQREQARIERADTLILVYPTYWWSMPALLKGWIDRVFSNGWAFDFDPEGSLTK
CCCCCCCCCHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHH
KLGKLSVHLIGIGGADPLTYERHGYGTAMKTQMDQGIFGYCGAEVHISKLLLNSENSGAV
HHCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCEEECCCHHEEEHHEECCCCCCCC
HALEMAEQLGRIISSEASPSTADTESLYYREHAGPNLK
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; NADPH; H+; acceptor

Specific reaction: NAD(P)H + H+ + acceptor = NAD(P)+ + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]