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The map label for this gene is pfkB [H]

Identifier: 62390775

GI number: 62390775

Start: 2012568

End: 2013560

Strand: Direct

Name: pfkB [H]

Synonym: cg2119

Alternate gene names: 62390775

Gene position: 2012568-2013560 (Clockwise)

Preceding gene: 62390774

Following gene: 62390776

Centisome position: 61.31

GC content: 58.21

Gene sequence:

>993_bases
ATGATCATCACATTCACCCCAAACCCGAGTATTGATTCCACGCTGTCGCTCGGCGAAGAGCTCTCCCGTGGATCCGTCCA
ACGACTTGATTCCGTCACCGCTGTCGCAGGTGGTAAAGGCATCAATGTCGCCCACGCTGTCTTGCTTGCGGGCTTTGAAA
CCTTGGCTGTGTTCCCAGCCGGCAAGCTCGACCCCTTCGTCCCACTGGTCCGCGACATCGGCTTGCCCGTGGAAACTGTT
GTGATCAACAAGAACGTCCGCACCAACACCACAGTCACCGAACCGGACGGCACCACCACCAAGCTCAACGGCCCCGGCGC
GCCGCTCAGCGAGCAGAAGCTCCGTAGCTTGGAAAAGGTGCTTATCGACGCGCTCCGCCCCGAAGTCACCTGGGTTGTCC
TGGCGGGCTCGCTGCCACCAGGGGCACCAGTTGACTGGTACGCGCGTCTCACCGCGTTGATCCATTCAGCACGCCCTGAC
GTTCGCGTGGCTGTCGATACCTCAGACAAGCCACTGATGGCGTTGGGCGAGAGCTTGGATACACCTGGCGCTGCTCCGAA
CCTGATTAAGCCAAATGGTCTGGAACTGGGCCAGCTGGCTAACACTGATGGTGAAGAGCTGGAGGCGCGTGCTGCGCAAG
GCGATTACGACGCCATCATCGCAGCTGCGGACGTACTGGTTAACCGTGGCATCGAACAGGTGCTTGTCACCTTGGGTGCC
GCAGGAGCGGTGTTGGTCAACGCAGAAGGTGCGTGGACTGCTACTTCTCCAAAGATTGATGTTGTATCCACCGTTGGAGC
TGGAGACTGTGCTCTTGCAGGTTTTGTTATGGCACGTTCCCAGAAGAAAACACTGGAGGAATCTCTGCTGAATGCCGTGT
CTTACGGCTCGACTGCGGCGTCTCTTCCTGGCACTACCATTCCTCGTCCTGACCAACTCGCCACAGCTGGTGCAACGGTC
ACCCAAGTCAAAGGATTGAAAGAATCAGCATGA

Upstream 100 bases:

>100_bases
ACCCTTTTTCCACCTTGGCTGATTTTGATGCCCTTGTTACCGATGACCACACGCTAGATTTTCCAGTTTTGCCCGACCAC
AACTTTCAGGTGGTAACCCC

Downstream 100 bases:

>100_bases
ATAGCGTAAATAATTCCTCGCTTGTCCGGCTGGATGTCGATTTCGGCGACTCCACCACGGATGTCATCAACAACCTTGCC
ACTGTTATTTTCGACGCTGG

Product: 1-phosphofructokinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MIITFTPNPSIDSTLSLGEELSRGSVQRLDSVTAVAGGKGINVAHAVLLAGFETLAVFPAGKLDPFVPLVRDIGLPVETV
VINKNVRTNTTVTEPDGTTTKLNGPGAPLSEQKLRSLEKVLIDALRPEVTWVVLAGSLPPGAPVDWYARLTALIHSARPD
VRVAVDTSDKPLMALGESLDTPGAAPNLIKPNGLELGQLANTDGEELEARAAQGDYDAIIAAADVLVNRGIEQVLVTLGA
AGAVLVNAEGAWTATSPKIDVVSTVGAGDCALAGFVMARSQKKTLEESLLNAVSYGSTAASLPGTTIPRPDQLATAGATV
TQVKGLKESA

Sequences:

>Translated_330_residues
MIITFTPNPSIDSTLSLGEELSRGSVQRLDSVTAVAGGKGINVAHAVLLAGFETLAVFPAGKLDPFVPLVRDIGLPVETV
VINKNVRTNTTVTEPDGTTTKLNGPGAPLSEQKLRSLEKVLIDALRPEVTWVVLAGSLPPGAPVDWYARLTALIHSARPD
VRVAVDTSDKPLMALGESLDTPGAAPNLIKPNGLELGQLANTDGEELEARAAQGDYDAIIAAADVLVNRGIEQVLVTLGA
AGAVLVNAEGAWTATSPKIDVVSTVGAGDCALAGFVMARSQKKTLEESLLNAVSYGSTAASLPGTTIPRPDQLATAGATV
TQVKGLKESA
>Mature_330_residues
MIITFTPNPSIDSTLSLGEELSRGSVQRLDSVTAVAGGKGINVAHAVLLAGFETLAVFPAGKLDPFVPLVRDIGLPVETV
VINKNVRTNTTVTEPDGTTTKLNGPGAPLSEQKLRSLEKVLIDALRPEVTWVVLAGSLPPGAPVDWYARLTALIHSARPD
VRVAVDTSDKPLMALGESLDTPGAAPNLIKPNGLELGQLANTDGEELEARAAQGDYDAIIAAADVLVNRGIEQVLVTLGA
AGAVLVNAEGAWTATSPKIDVVSTVGAGDCALAGFVMARSQKKTLEESLLNAVSYGSTAASLPGTTIPRPDQLATAGATV
TQVKGLKESA

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=327, Percent_Identity=31.8042813455657, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788017, Length=317, Percent_Identity=32.807570977918, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 34006; Mature: 34006

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIITFTPNPSIDSTLSLGEELSRGSVQRLDSVTAVAGGKGINVAHAVLLAGFETLAVFPA
CEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCC
GKLDPFVPLVRDIGLPVETVVINKNVRTNTTVTEPDGTTTKLNGPGAPLSEQKLRSLEKV
CCCCHHHHHHHHCCCCEEEEEEECCCCCCCEEECCCCCEEEECCCCCCCCHHHHHHHHHH
LIDALRPEVTWVVLAGSLPPGAPVDWYARLTALIHSARPDVRVAVDTSDKPLMALGESLD
HHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCCCC
TPGAAPNLIKPNGLELGQLANTDGEELEARAAQGDYDAIIAAADVLVNRGIEQVLVTLGA
CCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHCC
AGAVLVNAEGAWTATSPKIDVVSTVGAGDCALAGFVMARSQKKTLEESLLNAVSYGSTAA
CCEEEEECCCCEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SLPGTTIPRPDQLATAGATVTQVKGLKESA
CCCCCCCCCCCHHHHCCCHHHHHCCCCCCC
>Mature Secondary Structure
MIITFTPNPSIDSTLSLGEELSRGSVQRLDSVTAVAGGKGINVAHAVLLAGFETLAVFPA
CEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCC
GKLDPFVPLVRDIGLPVETVVINKNVRTNTTVTEPDGTTTKLNGPGAPLSEQKLRSLEKV
CCCCHHHHHHHHCCCCEEEEEEECCCCCCCEEECCCCCEEEECCCCCCCCHHHHHHHHHH
LIDALRPEVTWVVLAGSLPPGAPVDWYARLTALIHSARPDVRVAVDTSDKPLMALGESLD
HHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCCCC
TPGAAPNLIKPNGLELGQLANTDGEELEARAAQGDYDAIIAAADVLVNRGIEQVLVTLGA
CCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHCC
AGAVLVNAEGAWTATSPKIDVVSTVGAGDCALAGFVMARSQKKTLEESLLNAVSYGSTAA
CCEEEEECCCCEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SLPGTTIPRPDQLATAGATVTQVKGLKESA
CCCCCCCCCCCHHHHCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]