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The map label for this gene is ptsF [H]

Identifier: 62390776

GI number: 62390776

Start: 2013557

End: 2015623

Strand: Direct

Name: ptsF [H]

Synonym: cg2120

Alternate gene names: 62390776

Gene position: 2013557-2015623 (Clockwise)

Preceding gene: 62390775

Following gene: 62390777

Centisome position: 61.34

GC content: 59.26

Gene sequence:

>2067_bases
ATGAATAGCGTAAATAATTCCTCGCTTGTCCGGCTGGATGTCGATTTCGGCGACTCCACCACGGATGTCATCAACAACCT
TGCCACTGTTATTTTCGACGCTGGCCGAGCTTCCTCCGCCGACGCCCTTGCCAAAGACGCGCTGGATCGTGAAGCAAAGT
CCGGCACCGGCGTTCCTGGTCAAGTTGCTATCCCCCACTGCCGTTCCGAAGCCGTATCTGTCCCTACCTTGGGCTTTGCT
CGCCTGAGCAAGGGTGTGGACTTCAGCGGACCTGATGGCGATGCCAACTTGGTGTTCCTCATTGCAGCACCTGCTGGCGG
CGGCAAAGAGCACCTGAAGATCCTGTCCAAGCTTGCTCGCTCCTTGGTGAAGAAGGATTTCATCAAGGCTCTGCAGGAAG
CCACCACCGAGCAGGAAATCGTCGACGTTGTCGATGCCGTGCTCAACCCAGCACCAAAAACCACCGAGCCAGCTGCAGCT
CCGGCTGCGGCGGCGGTTGCTGAGAGTGGGGCGGCGTCGACAAGCGTTACTCGTATCGTGGCAATCACCGCATGCCCAAC
CGGTATCGCACACACCTACATGGCTGCGGATTCCCTGACGCAAAACGCGGAAGGCCGCGATGATGTGGAACTCGTTGTGG
AGACTCAGGGCTCTTCCGCTGTCACCCCAGTCGATCCGAAGATCATCGAAGCTGCCGACGCCGTCATCTTCGCCACCGAC
GTGGGAGTTAAAGACCGCGAGCGTTTCGCTGGCAAGCCAGTCATTGAATCCGGCGTCAAGCGCGCGATCAATGAGCCAGC
CAAGATGATCGACGAGGCCATCGCAGCCTCCAAGAACCCAAACGCCCGCAAGGTTTCCGGTTCCGGTGTCGCGGCATCTG
CTGAAACCACCGGCGAGAAGCTCGGCTGGGGCAAGCGCATCCAGCAGGCAGTCATGACCGGCGTGTCCTACATGGTTCCA
TTCGTAGCTGCCGGCGGCCTCCTGTTGGCTCTCGGCTTCGCATTCGGTGGATACGACATGGCGAACGGCTGGCAAGCAAT
CGCCACCCAGTTCTCTCTGACCAACCTGCCAGGCAACACCGTCGATGTTGACGGCGTGGCCATGACCTTCGAGCGTTCAG
GCTTCCTGTTGTACTTCGGCGCAGTCCTGTTCGCCACCGGCCAAGCAGCCATGGGCTTCATCGTGGCAGCCCTGTCTGGC
TACACCGCATACGCACTTGCTGGACGCCCAGGCATCGCGCCGGGCTTCGTCGGTGGCGCCATCTCCGTCACCATCGGCGC
TGGCTTCATTGGTGGTCTGGTTACCGGTATCTTGGCTGGTCTCATTGCCCTGTGGATTGGCTCCTGGAAGGTGCCACGCG
TGGTGCAGTCACTGATGCCTGTGGTCATCATCCCGCTACTTACCTCAGTGGTTGTTGGTCTCGTCATGTACCTCCTGCTG
GGTCGCCCACTCGCATCCATCATGACTGGTTTGCAGGACTGGCTATCGTCAATGTCCGGAAGCTCCGCCATCTTGCTGGG
TATCATCTTGGGCCTCATGATGTGTTTCGACCTCGGCGGACCAGTAAACAAGGCAGCCTACCTCTTTGGTACCGCAGGCC
TGTCTACCGGCGACCAAGCTTCCATGGAAATCATGGCCGCGATCATGGCAGCTGGCATGGTCCCACCAATCGCGTTGTCC
ATTGCTACCCTGCTGCGCAAGAAGCTGTTCACCCCAGCAGAGCAAGAAAACGGCAAGTCTTCCTGGCTGCTTGGCCTGGC
ATTCGTCTCCGAAGGTGCCATCCCATTCGCCGCAGCTGACCCATTCCGTGTGATCCCAGCAATGATGGCTGGCGGTGCAA
CCACTGGTGCAATCTCCATGGCACTGGGCGTCGGCTCTCGGGCTCCACACGGCGGTATCTTCGTGGTCTGGGCAATCGAA
CCATGGTGGGGCTGGCTCATCGCACTTGCAGCAGGCACCATCGTGTCCACCATCGTTGTCATCGCACTGAAGCAGTTCTG
GCCAAACAAGGCCGTCGCTGCAGAAGTCGCGAAGCAAGAAGCACAACAAGCAGCTGTAAACGCATAA

Upstream 100 bases:

>100_bases
CGACTGCGGCGTCTCTTCCTGGCACTACCATTCCTCGTCCTGACCAACTCGCCACAGCTGGTGCAACGGTCACCCAAGTC
AAAGGATTGAAAGAATCAGC

Downstream 100 bases:

>100_bases
TCGGACCTTGACCCGATGTCTGGTCGGACATTGTTTTTGCTTCCGGTAACGTGGCAAAACGAACAATGTCTCACTAGACT
AAAGTGAGATCGACATTAAA

Product: sugar specific PTS system, fructose/mannitol-specific transport protein

Products: NA

Alternate protein names: EIIABC-Fru; Fructose-specific phosphotransferase enzyme IIA component; EII-Fru; PTS system fructose-specific EIIA component; Fructose-specific phosphotransferase enzyme IIB component; EIII-Fru; PTS system fructose-specific EIIB component; Fructose permease IIC component; PTS system fructose-specific EIIC component [H]

Number of amino acids: Translated: 688; Mature: 688

Protein sequence:

>688_residues
MNSVNNSSLVRLDVDFGDSTTDVINNLATVIFDAGRASSADALAKDALDREAKSGTGVPGQVAIPHCRSEAVSVPTLGFA
RLSKGVDFSGPDGDANLVFLIAAPAGGGKEHLKILSKLARSLVKKDFIKALQEATTEQEIVDVVDAVLNPAPKTTEPAAA
PAAAAVAESGAASTSVTRIVAITACPTGIAHTYMAADSLTQNAEGRDDVELVVETQGSSAVTPVDPKIIEAADAVIFATD
VGVKDRERFAGKPVIESGVKRAINEPAKMIDEAIAASKNPNARKVSGSGVAASAETTGEKLGWGKRIQQAVMTGVSYMVP
FVAAGGLLLALGFAFGGYDMANGWQAIATQFSLTNLPGNTVDVDGVAMTFERSGFLLYFGAVLFATGQAAMGFIVAALSG
YTAYALAGRPGIAPGFVGGAISVTIGAGFIGGLVTGILAGLIALWIGSWKVPRVVQSLMPVVIIPLLTSVVVGLVMYLLL
GRPLASIMTGLQDWLSSMSGSSAILLGIILGLMMCFDLGGPVNKAAYLFGTAGLSTGDQASMEIMAAIMAAGMVPPIALS
IATLLRKKLFTPAEQENGKSSWLLGLAFVSEGAIPFAAADPFRVIPAMMAGGATTGAISMALGVGSRAPHGGIFVVWAIE
PWWGWLIALAAGTIVSTIVVIALKQFWPNKAVAAEVAKQEAQQAAVNA

Sequences:

>Translated_688_residues
MNSVNNSSLVRLDVDFGDSTTDVINNLATVIFDAGRASSADALAKDALDREAKSGTGVPGQVAIPHCRSEAVSVPTLGFA
RLSKGVDFSGPDGDANLVFLIAAPAGGGKEHLKILSKLARSLVKKDFIKALQEATTEQEIVDVVDAVLNPAPKTTEPAAA
PAAAAVAESGAASTSVTRIVAITACPTGIAHTYMAADSLTQNAEGRDDVELVVETQGSSAVTPVDPKIIEAADAVIFATD
VGVKDRERFAGKPVIESGVKRAINEPAKMIDEAIAASKNPNARKVSGSGVAASAETTGEKLGWGKRIQQAVMTGVSYMVP
FVAAGGLLLALGFAFGGYDMANGWQAIATQFSLTNLPGNTVDVDGVAMTFERSGFLLYFGAVLFATGQAAMGFIVAALSG
YTAYALAGRPGIAPGFVGGAISVTIGAGFIGGLVTGILAGLIALWIGSWKVPRVVQSLMPVVIIPLLTSVVVGLVMYLLL
GRPLASIMTGLQDWLSSMSGSSAILLGIILGLMMCFDLGGPVNKAAYLFGTAGLSTGDQASMEIMAAIMAAGMVPPIALS
IATLLRKKLFTPAEQENGKSSWLLGLAFVSEGAIPFAAADPFRVIPAMMAGGATTGAISMALGVGSRAPHGGIFVVWAIE
PWWGWLIALAAGTIVSTIVVIALKQFWPNKAVAAEVAKQEAQQAAVNA
>Mature_688_residues
MNSVNNSSLVRLDVDFGDSTTDVINNLATVIFDAGRASSADALAKDALDREAKSGTGVPGQVAIPHCRSEAVSVPTLGFA
RLSKGVDFSGPDGDANLVFLIAAPAGGGKEHLKILSKLARSLVKKDFIKALQEATTEQEIVDVVDAVLNPAPKTTEPAAA
PAAAAVAESGAASTSVTRIVAITACPTGIAHTYMAADSLTQNAEGRDDVELVVETQGSSAVTPVDPKIIEAADAVIFATD
VGVKDRERFAGKPVIESGVKRAINEPAKMIDEAIAASKNPNARKVSGSGVAASAETTGEKLGWGKRIQQAVMTGVSYMVP
FVAAGGLLLALGFAFGGYDMANGWQAIATQFSLTNLPGNTVDVDGVAMTFERSGFLLYFGAVLFATGQAAMGFIVAALSG
YTAYALAGRPGIAPGFVGGAISVTIGAGFIGGLVTGILAGLIALWIGSWKVPRVVQSLMPVVIIPLLTSVVVGLVMYLLL
GRPLASIMTGLQDWLSSMSGSSAILLGIILGLMMCFDLGGPVNKAAYLFGTAGLSTGDQASMEIMAAIMAAGMVPPIALS
IATLLRKKLFTPAEQENGKSSWLLGLAFVSEGAIPFAAADPFRVIPAMMAGGATTGAISMALGVGSRAPHGGIFVVWAIE
PWWGWLIALAAGTIVSTIVVIALKQFWPNKAVAAEVAKQEAQQAAVNA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788492, Length=493, Percent_Identity=44.421906693712, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1786951, Length=689, Percent_Identity=30.7692307692308, Blast_Score=290, Evalue=2e-79,
Organism=Escherichia coli, GI87082348, Length=518, Percent_Identity=31.4671814671815, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1790386, Length=344, Percent_Identity=35.4651162790698, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1788729, Length=419, Percent_Identity=26.2529832935561, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1790387, Length=95, Percent_Identity=46.3157894736842, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI2367327, Length=133, Percent_Identity=30.8270676691729, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788726, Length=114, Percent_Identity=34.2105263157895, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 70502; Mature: 70502

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2 ; PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSVNNSSLVRLDVDFGDSTTDVINNLATVIFDAGRASSADALAKDALDREAKSGTGVPG
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCC
QVAIPHCRSEAVSVPTLGFARLSKGVDFSGPDGDANLVFLIAAPAGGGKEHLKILSKLAR
CEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
SLVKKDFIKALQEATTEQEIVDVVDAVLNPAPKTTEPAAAPAAAAVAESGAASTSVTRIV
HHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCHHEEEE
AITACPTGIAHTYMAADSLTQNAEGRDDVELVVETQGSSAVTPVDPKIIEAADAVIFATD
EEEECCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHCCEEEEEEC
VGVKDRERFAGKPVIESGVKRAINEPAKMIDEAIAASKNPNARKVSGSGVAASAETTGEK
CCCCHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEECCCCCCCCCHHCHHH
LGWGKRIQQAVMTGVSYMVPFVAAGGLLLALGFAFGGYDMANGWQAIATQFSLTNLPGNT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEECCCCCC
VDVDGVAMTFERSGFLLYFGAVLFATGQAAMGFIVAALSGYTAYALAGRPGIAPGFVGGA
EECCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCE
ISVTIGAGFIGGLVTGILAGLIALWIGSWKVPRVVQSLMPVVIIPLLTSVVVGLVMYLLL
EEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRPLASIMTGLQDWLSSMSGSSAILLGIILGLMMCFDLGGPVNKAAYLFGTAGLSTGDQA
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHEEEEEECCCCCCCHH
SMEIMAAIMAAGMVPPIALSIATLLRKKLFTPAEQENGKSSWLLGLAFVSEGAIPFAAAD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHEEHHHHHHCCCCCCCCCC
PFRVIPAMMAGGATTGAISMALGVGSRAPHGGIFVVWAIEPWWGWLIALAAGTIVSTIVV
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHH
IALKQFWPNKAVAAEVAKQEAQQAAVNA
HHHHHHCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNSVNNSSLVRLDVDFGDSTTDVINNLATVIFDAGRASSADALAKDALDREAKSGTGVPG
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCC
QVAIPHCRSEAVSVPTLGFARLSKGVDFSGPDGDANLVFLIAAPAGGGKEHLKILSKLAR
CEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
SLVKKDFIKALQEATTEQEIVDVVDAVLNPAPKTTEPAAAPAAAAVAESGAASTSVTRIV
HHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCHHEEEE
AITACPTGIAHTYMAADSLTQNAEGRDDVELVVETQGSSAVTPVDPKIIEAADAVIFATD
EEEECCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHCCEEEEEEC
VGVKDRERFAGKPVIESGVKRAINEPAKMIDEAIAASKNPNARKVSGSGVAASAETTGEK
CCCCHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEECCCCCCCCCHHCHHH
LGWGKRIQQAVMTGVSYMVPFVAAGGLLLALGFAFGGYDMANGWQAIATQFSLTNLPGNT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEECCCCCC
VDVDGVAMTFERSGFLLYFGAVLFATGQAAMGFIVAALSGYTAYALAGRPGIAPGFVGGA
EECCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCE
ISVTIGAGFIGGLVTGILAGLIALWIGSWKVPRVVQSLMPVVIIPLLTSVVVGLVMYLLL
EEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRPLASIMTGLQDWLSSMSGSSAILLGIILGLMMCFDLGGPVNKAAYLFGTAGLSTGDQA
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHEEEEEECCCCCCCHH
SMEIMAAIMAAGMVPPIALSIATLLRKKLFTPAEQENGKSSWLLGLAFVSEGAIPFAAAD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHEEHHHHHHCCCCCCCCCC
PFRVIPAMMAGGATTGAISMALGVGSRAPHGGIFVVWAIEPWWGWLIALAAGTIVSTIVV
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHH
IALKQFWPNKAVAAEVAKQEAQQAAVNA
HHHHHHCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]