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The map label for this gene is glpR [H]

Identifier: 62390774

GI number: 62390774

Start: 2011777

End: 2012571

Strand: Direct

Name: glpR [H]

Synonym: cg2118

Alternate gene names: 62390774

Gene position: 2011777-2012571 (Clockwise)

Preceding gene: 62390772

Following gene: 62390775

Centisome position: 61.28

GC content: 52.2

Gene sequence:

>795_bases
ATGGTCAGCCAAACGGAAAGACAGCATGCAATTGCTTCTTTACTGGCACCAACTGGTGCGGTGTCTGTAGGAGATTTAGC
CGAGCATTTCCATGTGACAACCGAAACAGTGCGACGTGATCTTCGGATCATGGAGTCACTGGGTTTGTTGCAACGAGTTC
ACGGTGGCGCCATTAGCCCAGAGCCCATGGGTACGTCTCCCCCTCGGCTGAAACCTGCCTTGGGTAAAGGAATGCCACCG
GAACCCCGTGTTTTAGAACTTGCAGAAACTGCAGTTTCCCTCATCACACCTCTAGCACGCAGCATTTTCCTGGATTCAGG
TTTAGCGTGCACGGCGATTGCCACGGTGTTGGGGGATCCTCCAGAAGATGCCAGGTGGACTGTTGTTACAAGTTCCCCCG
GCGCTGTGATTGCCTTGTCCGCGACAGATGCCACCTCCACGGTGGTGCTGCACGGGCAGGTTCACGGTAATTGTTCTTCA
ATCATTGGGTCCACGGCAGTAGACATGATTTCGCAGTTGCGCGCTGATATCGCCTTCGTGGAGGTTGATGCGATTCAATC
CGATACAAGTCTGTGCACGTTTTTCCCGGAGACGATTCCCATCAAGCAAGCCATGATCAAAAACGCGGCTTTCACAGTTG
CTGTTCTCAGCCCGAGATCTCCCCAAGATCAAGAACTTCAACTTTTGAAGCACCCTTTTTCCACCTTGGCTGATTTTGAT
GCCCTTGTTACCGATGACCACACGCTAGATTTTCCAGTTTTGCCCGACCACAACTTTCAGGTGGTAACCCCATGA

Upstream 100 bases:

>100_bases
CCACAATCGGAACCAAAACAACACTGGTCAAAAACCAGTTTCCCGCTTGAACAAAATTTCTTCCACGTCAACACCAACTC
CAACATCAGCGAGGTTAAGC

Downstream 100 bases:

>100_bases
TCATCACATTCACCCCAAACCCGAGTATTGATTCCACGCTGTCGCTCGGCGAAGAGCTCTCCCGTGGATCCGTCCAACGA
CTTGATTCCGTCACCGCTGT

Product: sugar metabolism transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MVSQTERQHAIASLLAPTGAVSVGDLAEHFHVTTETVRRDLRIMESLGLLQRVHGGAISPEPMGTSPPRLKPALGKGMPP
EPRVLELAETAVSLITPLARSIFLDSGLACTAIATVLGDPPEDARWTVVTSSPGAVIALSATDATSTVVLHGQVHGNCSS
IIGSTAVDMISQLRADIAFVEVDAIQSDTSLCTFFPETIPIKQAMIKNAAFTVAVLSPRSPQDQELQLLKHPFSTLADFD
ALVTDDHTLDFPVLPDHNFQVVTP

Sequences:

>Translated_264_residues
MVSQTERQHAIASLLAPTGAVSVGDLAEHFHVTTETVRRDLRIMESLGLLQRVHGGAISPEPMGTSPPRLKPALGKGMPP
EPRVLELAETAVSLITPLARSIFLDSGLACTAIATVLGDPPEDARWTVVTSSPGAVIALSATDATSTVVLHGQVHGNCSS
IIGSTAVDMISQLRADIAFVEVDAIQSDTSLCTFFPETIPIKQAMIKNAAFTVAVLSPRSPQDQELQLLKHPFSTLADFD
ALVTDDHTLDFPVLPDHNFQVVTP
>Mature_264_residues
MVSQTERQHAIASLLAPTGAVSVGDLAEHFHVTTETVRRDLRIMESLGLLQRVHGGAISPEPMGTSPPRLKPALGKGMPP
EPRVLELAETAVSLITPLARSIFLDSGLACTAIATVLGDPPEDARWTVVTSSPGAVIALSATDATSTVVLHGQVHGNCSS
IIGSTAVDMISQLRADIAFVEVDAIQSDTSLCTFFPETIPIKQAMIKNAAFTVAVLSPRSPQDQELQLLKHPFSTLADFD
ALVTDDHTLDFPVLPDHNFQVVTP

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=215, Percent_Identity=27.906976744186, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789059, Length=246, Percent_Identity=31.3008130081301, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787540, Length=186, Percent_Identity=31.7204301075269, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI226510968, Length=244, Percent_Identity=29.9180327868852, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87082344, Length=203, Percent_Identity=26.1083743842365, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789519, Length=214, Percent_Identity=26.6355140186916, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28039; Mature: 28039

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSQTERQHAIASLLAPTGAVSVGDLAEHFHVTTETVRRDLRIMESLGLLQRVHGGAISP
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EPMGTSPPRLKPALGKGMPPEPRVLELAETAVSLITPLARSIFLDSGLACTAIATVLGDP
CCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
PEDARWTVVTSSPGAVIALSATDATSTVVLHGQVHGNCSSIIGSTAVDMISQLRADIAFV
CCCCEEEEEECCCCEEEEEEECCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHEEEE
EVDAIQSDTSLCTFFPETIPIKQAMIKNAAFTVAVLSPRSPQDQELQLLKHPFSTLADFD
EEECCCCCCCEEEECCCCCHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
ALVTDDHTLDFPVLPDHNFQVVTP
HHCCCCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MVSQTERQHAIASLLAPTGAVSVGDLAEHFHVTTETVRRDLRIMESLGLLQRVHGGAISP
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EPMGTSPPRLKPALGKGMPPEPRVLELAETAVSLITPLARSIFLDSGLACTAIATVLGDP
CCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
PEDARWTVVTSSPGAVIALSATDATSTVVLHGQVHGNCSSIIGSTAVDMISQLRADIAFV
CCCCEEEEEECCCCEEEEEEECCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHEEEE
EVDAIQSDTSLCTFFPETIPIKQAMIKNAAFTVAVLSPRSPQDQELQLLKHPFSTLADFD
EEECCCCCCCEEEECCCCCHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
ALVTDDHTLDFPVLPDHNFQVVTP
HHCCCCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]