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The map label for this gene is ctaB

Identifier: 62390455

GI number: 62390455

Start: 1664094

End: 1665065

Strand: Reverse

Name: ctaB

Synonym: cg1773

Alternate gene names: 62390455

Gene position: 1665065-1664094 (Counterclockwise)

Preceding gene: 62390461

Following gene: 62390448

Centisome position: 50.72

GC content: 55.66

Gene sequence:

>972_bases
ATGAGTGATTTGAAAATGCAACGTTCTGGAGGAGAACCCTTGGACACGATCAAGGCCTATATTGCGCTAACGAAGCCCAG
GGTTATTGAACTCCTCCTTGTCGCCACAATCCCCACAATGCTTCAGGCTGAACGCGGTGAGAACAACATTGTGCTCATCT
TGCTGACTGTGTTCGGTGGCTGGATGGGTGCGGCCGCCGCCAACACCTTCAACATGGTGGCAGACTCCGATATTGATCAG
CGCATGGGACGCACTAGGGCTCGCCCTTTGGTGCGCCACACCGTGAGTAATCGCGACGCCTCCATTTTTGCGTGGGTCCT
GACAGTGGCCAGCTTCTTGTGGCTGTGGCTGCTGTGCGATTCGATGCTCGCCGGCATCTTCGTGTTGATCACGATTTTCT
TCTACATTTTTGTCTACACCAAGTGGCTGAAGCGCCGCACGCACATGAATATCGTGTGGGGCGGAGCCGCAGGTTGTATG
CCAGTGCTCGTCGGCTGGGCAGTGATCGTTGATCAGTTTGAGCCAGGCGTTCCACAGCAGTGGTGGCAGGCAATTGTCCT
GTTCATGGTGATTTTCTTCTGGACCCCACCTCACACCTGGGCTCTGGCCATGAAGTACCGCGAAGACTACAAGGCGGCTG
GCGTCCCAATGCTTCCTGTCGTGCGCACCCCAGTCCAGGTCACCGCACAAATCGTGTGGTACTCCGTGGCAACTGTGCTG
ACCACCTTCTTGCTCATCCCAGCAACTGGTTGGATCTACGCAGCGATCGCCGTCATTTCCGGCGTCACCTTCTTGTTCAT
GGCCATCAAGCTGCACCTCGGCATCAAAAACGGTGGCAAGGTCAAGCCTCTGAAGCTGTTTATTTTGTCCAACAACTACT
TGGCAGTCCTCTTCGTGGCATTGTCCGTCGACGCGGTCCTCGGCCTTGAGACCATCGGCGAGATGCTCGGCTGGACCACC
ACCTTCTTCTAA

Upstream 100 bases:

>100_bases
AGTAAACACTCTGACGCTTCTGTCAGAGTCTGGGCCTTCAACGCAAGGTGCACACTCACCGCAGGGATATTTAAATAATA
AGGACTCACAACTTAAATAT

Downstream 100 bases:

>100_bases
AAGCTTGCTTTTCGACGAAAAGATCCTGGCTAACCTCACCGCGAGGCTAACCAGGATCTTTTTATGCGTGTTTAGTCCTT
CGGGATTTCCAAGACCAAAG

Product: protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase; Heme O synthase

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSDLKMQRSGGEPLDTIKAYIALTKPRVIELLLVATIPTMLQAERGENNIVLILLTVFGGWMGAAAANTFNMVADSDIDQ
RMGRTRARPLVRHTVSNRDASIFAWVLTVASFLWLWLLCDSMLAGIFVLITIFFYIFVYTKWLKRRTHMNIVWGGAAGCM
PVLVGWAVIVDQFEPGVPQQWWQAIVLFMVIFFWTPPHTWALAMKYREDYKAAGVPMLPVVRTPVQVTAQIVWYSVATVL
TTFLLIPATGWIYAAIAVISGVTFLFMAIKLHLGIKNGGKVKPLKLFILSNNYLAVLFVALSVDAVLGLETIGEMLGWTT
TFF

Sequences:

>Translated_323_residues
MSDLKMQRSGGEPLDTIKAYIALTKPRVIELLLVATIPTMLQAERGENNIVLILLTVFGGWMGAAAANTFNMVADSDIDQ
RMGRTRARPLVRHTVSNRDASIFAWVLTVASFLWLWLLCDSMLAGIFVLITIFFYIFVYTKWLKRRTHMNIVWGGAAGCM
PVLVGWAVIVDQFEPGVPQQWWQAIVLFMVIFFWTPPHTWALAMKYREDYKAAGVPMLPVVRTPVQVTAQIVWYSVATVL
TTFLLIPATGWIYAAIAVISGVTFLFMAIKLHLGIKNGGKVKPLKLFILSNNYLAVLFVALSVDAVLGLETIGEMLGWTT
TFF
>Mature_322_residues
SDLKMQRSGGEPLDTIKAYIALTKPRVIELLLVATIPTMLQAERGENNIVLILLTVFGGWMGAAAANTFNMVADSDIDQR
MGRTRARPLVRHTVSNRDASIFAWVLTVASFLWLWLLCDSMLAGIFVLITIFFYIFVYTKWLKRRTHMNIVWGGAAGCMP
VLVGWAVIVDQFEPGVPQQWWQAIVLFMVIFFWTPPHTWALAMKYREDYKAAGVPMLPVVRTPVQVTAQIVWYSVATVLT
TFLLIPATGWIYAAIAVISGVTFLFMAIKLHLGIKNGGKVKPLKLFILSNNYLAVLFVALSVDAVLGLETIGEMLGWTTT
FF

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily

Homologues:

Organism=Homo sapiens, GI17921982, Length=169, Percent_Identity=33.1360946745562, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1786631, Length=292, Percent_Identity=29.7945205479452, Blast_Score=114, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI71998235, Length=198, Percent_Identity=32.3232323232323, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6325085, Length=284, Percent_Identity=28.5211267605634, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19921064, Length=289, Percent_Identity=26.643598615917, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COXX_CORGB (A4QEE9)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138517.1
- STRING:   A4QEE9
- GeneID:   4991675
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1623
- eggNOG:   COG0109
- HOGENOM:   HBG656003
- OMA:   SYYQLTK
- ProtClustDB:   PRK04375
- HAMAP:   MF_00154
- InterPro:   IPR006369
- InterPro:   IPR000537
- PANTHER:   PTHR11048:SF3
- TIGRFAMs:   TIGR01473

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 36126; Mature: 35994

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12cf73cc)-; HASH(0x13b97780)-; HASH(0x13cf1f10)-; HASH(0x140ace84)-; HASH(0x140ad1cc)-; HASH(0x13b72afc)-; HASH(0x10c3117c)-; HASH(0x13eb0898)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
SDLKMQRSGGEPLDTIKAYIALTKPRVIELLLVATIPTMLQAERGENNIVLILLTVFGG
CCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCC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HHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA