| Definition | Vibrio fischeri ES114 chromosome chromosome II, complete sequence. |
|---|---|
| Accession | NC_006841 |
| Length | 1,330,333 |
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The map label for this gene is kduD [H]
Identifier: 59714180
GI number: 59714180
Start: 1121725
End: 1122480
Strand: Reverse
Name: kduD [H]
Synonym: VF_A0997
Alternate gene names: 59714180
Gene position: 1122480-1121725 (Counterclockwise)
Preceding gene: 59714181
Following gene: 59714179
Centisome position: 84.38
GC content: 42.2
Gene sequence:
>756_bases ATGAAACTTTTTGATTTAACTGGCAAAGTTGCCATTGTTACAGGGTGTAATACGGGTCTTGGTCAAGGCATGGCACTTGG TTTAGCGAAAGCGGGTGCAGATATTGTTGGTGTTGGCCATCAAGCCGCTCCCGAAACTGAAGAGCAAGTGAAAGCATTAG GTCGTAAGTTTCATTACATTACTGCAAACCTAATGAAGCAAGAAGGATTAGAAGAACTGGTTGCTGAAGCGGTTGAAGTA ATGGGGCACGTTGATATCTTAATTAATAATGCAGGTATTATTCGTCGTGAAGATTTACTCAAATTCTCAGAGCAAGATTG GGATGACGTAATTAATATTAACCAAAAGACGTTATTCTTCCTTTCTCAGAAAGTCGCTAAGCAATTTGTTAAGCAAGGAA ATGGCGGCAAAATCATCAATATTGCTTCTATGTTGTCATATCAAGGAGGGATCCGCGTTCCTTCTTATACCGCAAGTAAA TCAGCGGTTATGGGGTTAACCCGTGCCCTAGCGACTGAGCTTGCAGAACATAATATCAATGTTAATGCGATTGCTCCGGG TTACATGGCAACGGATAATACGGCAGCATTACGCGCAGATGAAGATCGAAATGCCGCTATTTTAGAGCGTATTCCTGCAA ATCGTTGGGGATTACCTTCTGATCTTGAAGGACCTGCAATCTTCCTAGCATCACCTGCAAGTGACTATATTAATGGTTAT ACGATTGCGGTTGATGGTGGCTGGTTAGCTCGTTAA
Upstream 100 bases:
>100_bases GGACCATGTAGCAATGACTGATATTAAGTAGTCATTTTAATTTTATTGTTATGTTGCTGATGTCTATCGGCAGCATATAT CAAGAATAGTAGGAAAGAAT
Downstream 100 bases:
>100_bases TCTAAAGAACAGAAGGAACAGCAAAATGACATTAGGAACAAAGCAAGACGTATTACAAGCGATGAAGCGAGTTTATCGCT ACCAAGCTGAAAACCAAACA
Product: 2-deoxy-D-gluconate 3-dehydrogenase
Products: NA
Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]
Number of amino acids: Translated: 251; Mature: 251
Protein sequence:
>251_residues MKLFDLTGKVAIVTGCNTGLGQGMALGLAKAGADIVGVGHQAAPETEEQVKALGRKFHYITANLMKQEGLEELVAEAVEV MGHVDILINNAGIIRREDLLKFSEQDWDDVININQKTLFFLSQKVAKQFVKQGNGGKIINIASMLSYQGGIRVPSYTASK SAVMGLTRALATELAEHNINVNAIAPGYMATDNTAALRADEDRNAAILERIPANRWGLPSDLEGPAIFLASPASDYINGY TIAVDGGWLAR
Sequences:
>Translated_251_residues MKLFDLTGKVAIVTGCNTGLGQGMALGLAKAGADIVGVGHQAAPETEEQVKALGRKFHYITANLMKQEGLEELVAEAVEV MGHVDILINNAGIIRREDLLKFSEQDWDDVININQKTLFFLSQKVAKQFVKQGNGGKIINIASMLSYQGGIRVPSYTASK SAVMGLTRALATELAEHNINVNAIAPGYMATDNTAALRADEDRNAAILERIPANRWGLPSDLEGPAIFLASPASDYINGY TIAVDGGWLAR >Mature_251_residues MKLFDLTGKVAIVTGCNTGLGQGMALGLAKAGADIVGVGHQAAPETEEQVKALGRKFHYITANLMKQEGLEELVAEAVEV MGHVDILINNAGIIRREDLLKFSEQDWDDVININQKTLFFLSQKVAKQFVKQGNGGKIINIASMLSYQGGIRVPSYTASK SAVMGLTRALATELAEHNINVNAIAPGYMATDNTAALRADEDRNAAILERIPANRWGLPSDLEGPAIFLASPASDYINGY TIAVDGGWLAR
Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=33.2, Blast_Score=128, Evalue=5e-30, Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=32.9411764705882, Blast_Score=122, Evalue=4e-28, Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=33.8775510204082, Blast_Score=119, Evalue=3e-27, Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=32.4110671936759, Blast_Score=112, Evalue=5e-25, Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=29.2490118577075, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=27.7777777777778, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=33.1632653061224, Blast_Score=97, Evalue=9e-21, Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=29.5081967213115, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI66933014, Length=249, Percent_Identity=28.9156626506024, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=32.4742268041237, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI4503301, Length=205, Percent_Identity=29.2682926829268, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=32.7868852459016, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=27.9527559055118, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=32.0388349514563, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI59889578, Length=198, Percent_Identity=29.7979797979798, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=31.1203319502075, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI20149619, Length=218, Percent_Identity=27.5229357798165, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=28.1853281853282, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI209862901, Length=197, Percent_Identity=28.4263959390863, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI19923983, Length=197, Percent_Identity=28.4263959390863, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI142976729, Length=195, Percent_Identity=26.1538461538462, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=30.4597701149425, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI210032110, Length=210, Percent_Identity=22.8571428571429, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI225579078, Length=209, Percent_Identity=28.2296650717703, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI302344755, Length=109, Percent_Identity=33.0275229357798, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=70.9163346613546, Blast_Score=372, Evalue=1e-104, Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=46.4285714285714, Blast_Score=226, Evalue=1e-60, Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=43.2, Blast_Score=190, Evalue=8e-50, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=34.9593495934959, Blast_Score=145, Evalue=2e-36, Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=34.2741935483871, Blast_Score=133, Evalue=1e-32, Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=34.8360655737705, Blast_Score=117, Evalue=5e-28, Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=32.9411764705882, Blast_Score=117, Evalue=6e-28, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=28.7449392712551, Blast_Score=101, Evalue=4e-23, Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=30.6772908366534, Blast_Score=95, Evalue=5e-21, Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=26.171875, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=28.1124497991968, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=8e-15, Organism=Escherichia coli, GI1787820, Length=237, Percent_Identity=26.1603375527426, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1787526, Length=208, Percent_Identity=27.4038461538462, Blast_Score=69, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=33.0612244897959, Blast_Score=129, Evalue=2e-30, Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=32.3770491803279, Blast_Score=124, Evalue=3e-29, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=31.6, Blast_Score=123, Evalue=7e-29, Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=33.7301587301587, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=30.2788844621514, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=31.1284046692607, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=30.7692307692308, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=30.8, Blast_Score=103, Evalue=9e-23, Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=29.8850574712644, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=29.277566539924, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=30.8550185873606, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=31.9838056680162, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=28.3524904214559, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=29.7709923664122, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=29.4573643410853, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=28.1853281853282, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17568967, Length=194, Percent_Identity=34.5360824742268, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=30.7692307692308, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=30.2681992337165, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=28.1954887218045, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17564282, Length=189, Percent_Identity=29.6296296296296, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=29.1187739463602, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17565030, Length=262, Percent_Identity=31.2977099236641, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=29.6577946768061, Blast_Score=88, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=28.3018867924528, Blast_Score=87, Evalue=5e-18, Organism=Caenorhabditis elegans, GI193203115, Length=191, Percent_Identity=29.3193717277487, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI193203117, Length=193, Percent_Identity=28.4974093264249, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=27.3764258555133, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17561272, Length=180, Percent_Identity=32.2222222222222, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=30.8300395256917, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17536651, Length=257, Percent_Identity=26.4591439688716, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=26.5873015873016, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=27.0833333333333, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI71982365, Length=220, Percent_Identity=28.1818181818182, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17508651, Length=256, Percent_Identity=26.953125, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI86565303, Length=266, Percent_Identity=27.4436090225564, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17555612, Length=220, Percent_Identity=29.5454545454545, Blast_Score=67, Evalue=6e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=34.0314136125654, Blast_Score=90, Evalue=3e-19, Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=28.6274509803922, Blast_Score=80, Evalue=3e-16, Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=27.6923076923077, Blast_Score=62, Evalue=7e-11, Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=33.596837944664, Blast_Score=130, Evalue=6e-31, Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=30.9236947791165, Blast_Score=120, Evalue=9e-28, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=32.1285140562249, Blast_Score=109, Evalue=1e-24, Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=30.327868852459, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=31.7269076305221, Blast_Score=103, Evalue=7e-23, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=27.8225806451613, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=28.8537549407115, Blast_Score=97, Evalue=9e-21, Organism=Drosophila melanogaster, GI18859837, Length=255, Percent_Identity=32.156862745098, Blast_Score=94, Evalue=6e-20, Organism=Drosophila melanogaster, GI17737361, Length=251, Percent_Identity=30.2788844621514, Blast_Score=87, Evalue=9e-18, Organism=Drosophila melanogaster, GI24640492, Length=218, Percent_Identity=30.7339449541284, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=30.2564102564103, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI24649181, Length=198, Percent_Identity=30.3030303030303, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24644337, Length=251, Percent_Identity=28.2868525896414, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI21357673, Length=192, Percent_Identity=28.6458333333333, Blast_Score=77, Evalue=9e-15, Organism=Drosophila melanogaster, GI161076933, Length=206, Percent_Identity=31.0679611650485, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24584748, Length=206, Percent_Identity=31.0679611650485, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24584744, Length=202, Percent_Identity=29.7029702970297, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI28574402, Length=202, Percent_Identity=29.7029702970297, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI17647419, Length=231, Percent_Identity=20.7792207792208, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24586328, Length=202, Percent_Identity=28.7128712871287, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24581726, Length=214, Percent_Identity=26.6355140186916, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011286 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.127 [H]
Molecular weight: Translated: 26911; Mature: 26911
Theoretical pI: Translated: 5.35; Mature: 5.35
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKLFDLTGKVAIVTGCNTGLGQGMALGLAKAGADIVGVGHQAAPETEEQVKALGRKFHYI CEEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHH TANLMKQEGLEELVAEAVEVMGHVDILINNAGIIRREDLLKFSEQDWDDVININQKTLFF HHHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCEEHHHHHHHCCCCHHHHHCCCCHHHHH LSQKVAKQFVKQGNGGKIINIASMLSYQGGIRVPSYTASKSAVMGLTRALATELAEHNIN HHHHHHHHHHHCCCCCCEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC VNAIAPGYMATDNTAALRADEDRNAAILERIPANRWGLPSDLEGPAIFLASPASDYINGY EEEECCCEEECCCCEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEECCCHHHHCCE TIAVDGGWLAR EEEECCCEECC >Mature Secondary Structure MKLFDLTGKVAIVTGCNTGLGQGMALGLAKAGADIVGVGHQAAPETEEQVKALGRKFHYI CEEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHH TANLMKQEGLEELVAEAVEVMGHVDILINNAGIIRREDLLKFSEQDWDDVININQKTLFF HHHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCEEHHHHHHHCCCCHHHHHCCCCHHHHH LSQKVAKQFVKQGNGGKIINIASMLSYQGGIRVPSYTASKSAVMGLTRALATELAEHNIN HHHHHHHHHHHCCCCCCEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC VNAIAPGYMATDNTAALRADEDRNAAILERIPANRWGLPSDLEGPAIFLASPASDYINGY EEEECCCEEECCCCEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEECCCHHHHCCE TIAVDGGWLAR EEEECCCEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9278503; 2836407; 1766386 [H]