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The map label for this gene is rpoE4 [H]

Identifier: 59713949

GI number: 59713949

Start: 861710

End: 862321

Strand: Reverse

Name: rpoE4 [H]

Synonym: VF_A0766

Alternate gene names: 59713949

Gene position: 862321-861710 (Counterclockwise)

Preceding gene: 59713951

Following gene: 59713948

Centisome position: 64.82

GC content: 37.42

Gene sequence:

>612_bases
ATGCATATTCAACAGGTAGAGGTTGTCACTCGAGTGAGCATTGCAGATAGACCGAACAGTGACAAAGACAGTTCGGTTCA
AATAGATTCTTGGTTAAGAAAAGTCGGTGAGACGCAAGATAAAGTTGCATTCGCTGAGCTTTTTAAGTGGTTTGCTCCTA
AGATCAAAATGTATGGTTTAAAACGATTTAATGATCAAAGTCTAGCAATGGACTTAGTTCAAGAAACTATGACGTTAGTT
TGGCGAAAAGCCACATTATTCAACCGTAGTAAAGGCAATGCCTCAGGTTGGATTTTTACTATCATGCGTAACCATAGCTT
CGATATGTTAAGAAAAATTCAAACTAATAAAGAAGATACAATTAGTGAGGATTTGTGGCCACTATATGACAAACAAGTTG
AAACCAATTCGGTTGATTTCCTCGAGAATAAGAATCTTGAAAAAGCACTCATGCTATTACCATTACCTCAACGAATTGTT
ATTGAAGGACTATATGTGCAAGGGCTAACTCAGCAAGAGTTATCTGAACAGCTTGCAGAGCCAATAGGAACGATAAAATC
TCGATTACGCTTAGCGTTAACTAAATTGCGTCAGGAGTATGAGCATGAATAA

Upstream 100 bases:

>100_bases
TTGTGATCATTCAACTATGCTCAAAATAAGATGTTTTATATTTTATAGTGATCTTTTTTATTCTCTCTCTCGTAATAGAT
AAAAAATAGAGGGAGTCAAT

Downstream 100 bases:

>100_bases
GATCACTTACCATCCCAAAGATGAGCTTTTGAGTTCTCATGCAAATGGTGATTTACCCGAATCATTAGCGGTGGCTATTT
CATTACACTGTGAATTATGT

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-K factor [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MHIQQVEVVTRVSIADRPNSDKDSSVQIDSWLRKVGETQDKVAFAELFKWFAPKIKMYGLKRFNDQSLAMDLVQETMTLV
WRKATLFNRSKGNASGWIFTIMRNHSFDMLRKIQTNKEDTISEDLWPLYDKQVETNSVDFLENKNLEKALMLLPLPQRIV
IEGLYVQGLTQQELSEQLAEPIGTIKSRLRLALTKLRQEYEHE

Sequences:

>Translated_203_residues
MHIQQVEVVTRVSIADRPNSDKDSSVQIDSWLRKVGETQDKVAFAELFKWFAPKIKMYGLKRFNDQSLAMDLVQETMTLV
WRKATLFNRSKGNASGWIFTIMRNHSFDMLRKIQTNKEDTISEDLWPLYDKQVETNSVDFLENKNLEKALMLLPLPQRIV
IEGLYVQGLTQQELSEQLAEPIGTIKSRLRLALTKLRQEYEHE
>Mature_203_residues
MHIQQVEVVTRVSIADRPNSDKDSSVQIDSWLRKVGETQDKVAFAELFKWFAPKIKMYGLKRFNDQSLAMDLVQETMTLV
WRKATLFNRSKGNASGWIFTIMRNHSFDMLRKIQTNKEDTISEDLWPLYDKQVETNSVDFLENKNLEKALMLLPLPQRIV
IEGLYVQGLTQQELSEQLAEPIGTIKSRLRLALTKLRQEYEHE

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR007627
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 23703; Mature: 23703

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIQQVEVVTRVSIADRPNSDKDSSVQIDSWLRKVGETQDKVAFAELFKWFAPKIKMYGL
CCCHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHH
KRFNDQSLAMDLVQETMTLVWRKATLFNRSKGNASGWIFTIMRNHSFDMLRKIQTNKEDT
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHH
ISEDLWPLYDKQVETNSVDFLENKNLEKALMLLPLPQRIVIEGLYVQGLTQQELSEQLAE
HHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHH
PIGTIKSRLRLALTKLRQEYEHE
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHIQQVEVVTRVSIADRPNSDKDSSVQIDSWLRKVGETQDKVAFAELFKWFAPKIKMYGL
CCCHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHH
KRFNDQSLAMDLVQETMTLVWRKATLFNRSKGNASGWIFTIMRNHSFDMLRKIQTNKEDT
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHH
ISEDLWPLYDKQVETNSVDFLENKNLEKALMLLPLPQRIVIEGLYVQGLTQQELSEQLAE
HHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHH
PIGTIKSRLRLALTKLRQEYEHE
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]