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The map label for this gene is trkA [H]

Identifier: 59713153

GI number: 59713153

Start: 2866127

End: 2867503

Strand: Direct

Name: trkA [H]

Synonym: VF_2546

Alternate gene names: 59713153

Gene position: 2866127-2867503 (Clockwise)

Preceding gene: 59713152

Following gene: 59713154

Centisome position: 98.92

GC content: 43.79

Gene sequence:

>1377_bases
ATGAAAATCATCATCTTAGGTGCGGGTCAAGTGGGCGGCACATTAGCTGAGAACTTGGTGGGCGAAAACAACGATATTAC
GGTTGTTGATAAGAGCTCTGAACGACTGCGTGAGTTGCAAGATAAATACGATTTACGTGTAGTTCAAGGGTTTGCTAGTC
ACCCAGATACATTAAGAGAAGCCGGTGCACAAGATGCCGATATGTTAGTTGCCGTCACTAATTCCGACGAAACGAACATG
ATCGCCTGTCAAATTGCATTTACTGTATTTAATACACCAAACCGTATTGCTCGTATTCGTTCTCCTGAATATTTAAGAGA
AAAAGAACGCCTTTTCCAATCAGATGCGATTCCAGTTGATCATTTGATCGCTCCAGAAGAACTCGTTACTGGATACATCG
AACGCTTAATCGAATACCCAGGTGCACTTCAAGTAGCCAGCTTTGCAGAGAAGAAAGTAAGTCTTGTTGCTGTTAAAGCC
TATTACGGTGGTCCTCTCGTCGGTAATGCGTTATCCGCACTTCGTGATCACATGCCTCATATTGATACTCGTGTTGCGGC
TATTTTCCGTCAAGGCCGACCAATTCGCCCTCAGGGAACGACCGTTATCGAAGCTGACGATGAAGTATTCTTTGTTGCAG
CAAGTAACCATATCCGTGCAGTAATGAGTGAATTACAGCGTTTAGAGCGCCCATACAAACGAATTATGATTGTTGGTGGC
GGTAATATCGGAGCAGGTCTTGCGAGACGCTTAGAACAAAACTACAGCGTTAAACTGATTGAACGTAATATGAAGCGAGC
AGAAGAGTTATCTGAACTGCTTGAAGAAAGCATTGTATTTTGTGGTGATGCTGCAGACCAAGAGCTACTAAGTGAAGAAC
ACATCGATCAAGTTGATGTGTTCATCGCTGTCACTAACGAAGACGAAGCCAATATCATGTCAGCCATGCTAGCAAAACGC
ATGGGTGCTAAAAAAGTCATGGTATTGATTCAACGTGGCGCTTATGTGGATTTAGTGCAGGGTGGCGTTATTGATGTGGC
CATCTCACCACAACAAGCGACAATTTCAGCGCTATTAACGCATGTTCGTCGTGCTGATATCGTTAACGTATCCTCTCTTC
GTCGTGGTGCAGCCGAAGCGATTGAAGCCATTGCACATGGTGATGAAACCACATCAAAAGTCGTTGGTAGAGAAGTTCAA
AATATAAAACTACCACCAGGCACAACCATTGGTGCAATTGTTCGAGGTGAAGAAGTATTAATCGCACACGATAAGACCGT
GATAGAGCAGGATGATCACGTTGTTATGTTCCTAGTGGATAAGAAATACGTTCAGGATGTAGAACGCTTATTCCAACCGA
GTCCGTTCTTCTTATAA

Upstream 100 bases:

>100_bases
AAAACCAGGACGTCAAATTCTTCCAGGTGAAGAGAATATGGACGGCTTCTACTACGCTGTTCTACAAAAAGCCTAATCGG
AATACGAGCGAGCAAACGGT

Downstream 100 bases:

>100_bases
TTATGGTTAACTACAAACCGATCCTATTTGTAATAGGGCTTGTTTTATCAAAACTCGCCCTATTTATGTATATCCCGACA
CTCGTAGCACTGTTTACAGG

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKIIILGAGQVGGTLAENLVGENNDITVVDKSSERLRELQDKYDLRVVQGFASHPDTLREAGAQDADMLVAVTNSDETNM
IACQIAFTVFNTPNRIARIRSPEYLREKERLFQSDAIPVDHLIAPEELVTGYIERLIEYPGALQVASFAEKKVSLVAVKA
YYGGPLVGNALSALRDHMPHIDTRVAAIFRQGRPIRPQGTTVIEADDEVFFVAASNHIRAVMSELQRLERPYKRIMIVGG
GNIGAGLARRLEQNYSVKLIERNMKRAEELSELLEESIVFCGDAADQELLSEEHIDQVDVFIAVTNEDEANIMSAMLAKR
MGAKKVMVLIQRGAYVDLVQGGVIDVAISPQQATISALLTHVRRADIVNVSSLRRGAAEAIEAIAHGDETTSKVVGREVQ
NIKLPPGTTIGAIVRGEEVLIAHDKTVIEQDDHVVMFLVDKKYVQDVERLFQPSPFFL

Sequences:

>Translated_458_residues
MKIIILGAGQVGGTLAENLVGENNDITVVDKSSERLRELQDKYDLRVVQGFASHPDTLREAGAQDADMLVAVTNSDETNM
IACQIAFTVFNTPNRIARIRSPEYLREKERLFQSDAIPVDHLIAPEELVTGYIERLIEYPGALQVASFAEKKVSLVAVKA
YYGGPLVGNALSALRDHMPHIDTRVAAIFRQGRPIRPQGTTVIEADDEVFFVAASNHIRAVMSELQRLERPYKRIMIVGG
GNIGAGLARRLEQNYSVKLIERNMKRAEELSELLEESIVFCGDAADQELLSEEHIDQVDVFIAVTNEDEANIMSAMLAKR
MGAKKVMVLIQRGAYVDLVQGGVIDVAISPQQATISALLTHVRRADIVNVSSLRRGAAEAIEAIAHGDETTSKVVGREVQ
NIKLPPGTTIGAIVRGEEVLIAHDKTVIEQDDHVVMFLVDKKYVQDVERLFQPSPFFL
>Mature_458_residues
MKIIILGAGQVGGTLAENLVGENNDITVVDKSSERLRELQDKYDLRVVQGFASHPDTLREAGAQDADMLVAVTNSDETNM
IACQIAFTVFNTPNRIARIRSPEYLREKERLFQSDAIPVDHLIAPEELVTGYIERLIEYPGALQVASFAEKKVSLVAVKA
YYGGPLVGNALSALRDHMPHIDTRVAAIFRQGRPIRPQGTTVIEADDEVFFVAASNHIRAVMSELQRLERPYKRIMIVGG
GNIGAGLARRLEQNYSVKLIERNMKRAEELSELLEESIVFCGDAADQELLSEEHIDQVDVFIAVTNEDEANIMSAMLAKR
MGAKKVMVLIQRGAYVDLVQGGVIDVAISPQQATISALLTHVRRADIVNVSSLRRGAAEAIEAIAHGDETTSKVVGREVQ
NIKLPPGTTIGAIVRGEEVLIAHDKTVIEQDDHVVMFLVDKKYVQDVERLFQPSPFFL

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=458, Percent_Identity=79.6943231441048, Blast_Score=764, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 50516; Mature: 50516

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIILGAGQVGGTLAENLVGENNDITVVDKSSERLRELQDKYDLRVVQGFASHPDTLRE
CEEEEEECCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AGAQDADMLVAVTNSDETNMIACQIAFTVFNTPNRIARIRSPEYLREKERLFQSDAIPVD
CCCCCCCEEEEEECCCCCCEEEEEEEEEEECCCHHHHCCCCCHHHHHHHHHHHCCCCCHH
HLIAPEELVTGYIERLIEYPGALQVASFAEKKVSLVAVKAYYGGPLVGNALSALRDHMPH
HCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHCCCC
IDTRVAAIFRQGRPIRPQGTTVIEADDEVFFVAASNHIRAVMSELQRLERPYKRIMIVGG
HHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHCHHHEEEEEEC
GNIGAGLARRLEQNYSVKLIERNMKRAEELSELLEESIVFCGDAADQELLSEEHIDQVDV
CCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHCCCEEEE
FIAVTNEDEANIMSAMLAKRMGAKKVMVLIQRGAYVDLVQGGVIDVAISPQQATISALLT
EEEEECCCHHHHHHHHHHHHHCHHHHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHH
HVRRADIVNVSSLRRGAAEAIEAIAHGDETTSKVVGREVQNIKLPPGTTIGAIVRGEEVL
HHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCCCEEEEEECCEEE
IAHDKTVIEQDDHVVMFLVDKKYVQDVERLFQPSPFFL
EEECCEEEECCCCEEEEEECHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKIIILGAGQVGGTLAENLVGENNDITVVDKSSERLRELQDKYDLRVVQGFASHPDTLRE
CEEEEEECCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AGAQDADMLVAVTNSDETNMIACQIAFTVFNTPNRIARIRSPEYLREKERLFQSDAIPVD
CCCCCCCEEEEEECCCCCCEEEEEEEEEEECCCHHHHCCCCCHHHHHHHHHHHCCCCCHH
HLIAPEELVTGYIERLIEYPGALQVASFAEKKVSLVAVKAYYGGPLVGNALSALRDHMPH
HCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHCCCC
IDTRVAAIFRQGRPIRPQGTTVIEADDEVFFVAASNHIRAVMSELQRLERPYKRIMIVGG
HHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHCHHHEEEEEEC
GNIGAGLARRLEQNYSVKLIERNMKRAEELSELLEESIVFCGDAADQELLSEEHIDQVDV
CCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHCCCEEEE
FIAVTNEDEANIMSAMLAKRMGAKKVMVLIQRGAYVDLVQGGVIDVAISPQQATISALLT
EEEEECCCHHHHHHHHHHHHHCHHHHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHH
HVRRADIVNVSSLRRGAAEAIEAIAHGDETTSKVVGREVQNIKLPPGTTIGAIVRGEEVL
HHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCCCEEEEEECCEEE
IAHDKTVIEQDDHVVMFLVDKKYVQDVERLFQPSPFFL
EEECCEEEECCCCEEEEEECHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7948029; 9720051 [H]