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The map label for this gene is trkH2 [H]

Identifier: 59713154

GI number: 59713154

Start: 2867506

End: 2868951

Strand: Direct

Name: trkH2 [H]

Synonym: VF_2547

Alternate gene names: 59713154

Gene position: 2867506-2868951 (Clockwise)

Preceding gene: 59713153

Following gene: 172087784

Centisome position: 98.96

GC content: 41.42

Gene sequence:

>1446_bases
ATGGTTAACTACAAACCGATCCTATTTGTAATAGGGCTTGTTTTATCAAAACTCGCCCTATTTATGTATATCCCGACACT
CGTAGCACTGTTTACAGGTACTGGTGGTTTTATCGAATTTGGACAAGCGGTTGCCATTACTCACATAGTGGCATTTGCTT
GTTTAACTTTGGGCCGCAGCAAACAGTTTAAAATGAACGTGCGGGATATGTTTTTAATAACAACACTTGTGTGGACCATT
GCAAGTGCTTTCGCTGCACTTCCTTTTGTGTTTATTAACCACATCAGCTTTACCGACGCTTACTTTGAAACCATGTCAGG
CATCACAACGACTGGTTCAACGGTGCTCAGTGGGTTAGATGATATGGCACCAAGTATTTTATTATGGCGTTCAACGTTAC
AGTGGCTAGGTGGTGTAGGTTTTATTGTAATGGCAGTAGCCATCTTACCTATGCTCAATGTCGGTGGTATGCGACTGTTC
CAAACGGAATCTTCTGATTGGTCAGATAAAAGCGCCCCGAGAACCAAATATGTCGCCAAATACATTGTGAATGTGTATTT
AAGCTTAACCTTACTGTGTTTCTTAAGCTATTTAGTGACAGGGATGACACCATTTGAAGCCATAAACCACGCATTTACTA
CGCTATCCACAGGAGGATACTCCACCTCTGATAGTTCAATGAATCGTTTTTCAAATAGCACGCACTGGGTAGCATCATTC
TTTATGTTTGCAGGTGGTTTGCCTTTCTTACTCTTTATTCAAGTACTTAAAAAGCGCGATCCCAAAGTTCTCTTTAAAGA
TGCTCAGGTCGTTGGGTTTCTAAAATTAGTATTAATCACCAGCTTATTAGTTGCGATTTGGTTAGTGATTCATAATGACT
ATGCCATTATGGATGCGTTACGAGTCTCTGTGTTTAATATTGTTTCTGTTGTGACTACAACGGGTTTTGGTTTGGATGAC
TTTACATCGTGGGGAGCATTCCCTGCCATCATCTTTGCTTTTGTTATGCTAACAGGTGCATGTTCAGGTTCGACAGCGGG
TGGTATAAAAATCTTCCGCTTCCAGATTGCATCAACCATGTTGAATAAACAGATGATGAAACTGATCCACCCATCAGGGA
TCTTTGTTCAACGTTATAATGGCCGTCCAGTAACCGATGACATTGCACGTTCGGTTGTTGCTCTTGTCTTTACCTTCCTA
TTAACCATCATCATTATCTCTGCGTTATTAGGTAGCTTAGGACTTGATCCCGTAACGAGTATCACCAGTGCCGTTACTGC
TGTTGCTAACGTAGGTCCAGGTATGGGGCATATTGTTGGCCCAACAGGTAACTTTGCAACACTACCAGATACGGCAAAAT
GGATACTCAGTATTGGAATGTTGATGGGGCGATTAGAAATTTTAACCGTATTGGTTTTATTCTTCCCAGCCTTTTGGAAG
GGTTAA

Upstream 100 bases:

>100_bases
TGATAGAGCAGGATGATCACGTTGTTATGTTCCTAGTGGATAAGAAATACGTTCAGGATGTAGAACGCTTATTCCAACCG
AGTCCGTTCTTCTTATAATT

Downstream 100 bases:

>100_bases
CACAGTAACAATGAAAAATGACCTAGTATTTCTACTAGGCCATTTTTATTTATAAACAGGTATTAAACCGGCTTTACGTA
ATAATAAATCGACAAGAATT

Product: Trk system potassium uptake protein TrkH

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MVNYKPILFVIGLVLSKLALFMYIPTLVALFTGTGGFIEFGQAVAITHIVAFACLTLGRSKQFKMNVRDMFLITTLVWTI
ASAFAALPFVFINHISFTDAYFETMSGITTTGSTVLSGLDDMAPSILLWRSTLQWLGGVGFIVMAVAILPMLNVGGMRLF
QTESSDWSDKSAPRTKYVAKYIVNVYLSLTLLCFLSYLVTGMTPFEAINHAFTTLSTGGYSTSDSSMNRFSNSTHWVASF
FMFAGGLPFLLFIQVLKKRDPKVLFKDAQVVGFLKLVLITSLLVAIWLVIHNDYAIMDALRVSVFNIVSVVTTTGFGLDD
FTSWGAFPAIIFAFVMLTGACSGSTAGGIKIFRFQIASTMLNKQMMKLIHPSGIFVQRYNGRPVTDDIARSVVALVFTFL
LTIIIISALLGSLGLDPVTSITSAVTAVANVGPGMGHIVGPTGNFATLPDTAKWILSIGMLMGRLEILTVLVLFFPAFWK
G

Sequences:

>Translated_481_residues
MVNYKPILFVIGLVLSKLALFMYIPTLVALFTGTGGFIEFGQAVAITHIVAFACLTLGRSKQFKMNVRDMFLITTLVWTI
ASAFAALPFVFINHISFTDAYFETMSGITTTGSTVLSGLDDMAPSILLWRSTLQWLGGVGFIVMAVAILPMLNVGGMRLF
QTESSDWSDKSAPRTKYVAKYIVNVYLSLTLLCFLSYLVTGMTPFEAINHAFTTLSTGGYSTSDSSMNRFSNSTHWVASF
FMFAGGLPFLLFIQVLKKRDPKVLFKDAQVVGFLKLVLITSLLVAIWLVIHNDYAIMDALRVSVFNIVSVVTTTGFGLDD
FTSWGAFPAIIFAFVMLTGACSGSTAGGIKIFRFQIASTMLNKQMMKLIHPSGIFVQRYNGRPVTDDIARSVVALVFTFL
LTIIIISALLGSLGLDPVTSITSAVTAVANVGPGMGHIVGPTGNFATLPDTAKWILSIGMLMGRLEILTVLVLFFPAFWK
G
>Mature_481_residues
MVNYKPILFVIGLVLSKLALFMYIPTLVALFTGTGGFIEFGQAVAITHIVAFACLTLGRSKQFKMNVRDMFLITTLVWTI
ASAFAALPFVFINHISFTDAYFETMSGITTTGSTVLSGLDDMAPSILLWRSTLQWLGGVGFIVMAVAILPMLNVGGMRLF
QTESSDWSDKSAPRTKYVAKYIVNVYLSLTLLCFLSYLVTGMTPFEAINHAFTTLSTGGYSTSDSSMNRFSNSTHWVASF
FMFAGGLPFLLFIQVLKKRDPKVLFKDAQVVGFLKLVLITSLLVAIWLVIHNDYAIMDALRVSVFNIVSVVTTTGFGLDD
FTSWGAFPAIIFAFVMLTGACSGSTAGGIKIFRFQIASTMLNKQMMKLIHPSGIFVQRYNGRPVTDDIARSVVALVFTFL
LTIIIISALLGSLGLDPVTSITSAVTAVANVGPGMGHIVGPTGNFATLPDTAKWILSIGMLMGRLEILTVLVLFFPAFWK
G

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=489, Percent_Identity=34.1513292433538, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI1787626, Length=432, Percent_Identity=33.1018518518519, Blast_Score=217, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52372; Mature: 52372

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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C
>Mature Secondary Structure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C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]