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The map label for this gene is recG [H]

Identifier: 59713067

GI number: 59713067

Start: 2757590

End: 2759671

Strand: Direct

Name: recG [H]

Synonym: VF_2460

Alternate gene names: 59713067

Gene position: 2757590-2759671 (Clockwise)

Preceding gene: 59713066

Following gene: 59713083

Centisome position: 95.17

GC content: 41.79

Gene sequence:

>2082_bases
ATGACCAATACCATGCTTTCTGCCATTCCATTAACCTCTCTTGCTGGTGTGGGAGCAAAAGTCGCAGAAAAGCTCGAAAA
AATAGGATTGGTCTCCATTCAAGATTTACTTTTCCACCTTCCATTACGCTATGAAGATCGAACACGTGTATATCCAATGG
CACGTGTTCACTCTGGTTTGTTTGCCGCAGTGCAAGGCAAAGTCATGTCTTGCGATATGCAATTTGGCAAAAGAAAAATG
TTACTGGTAAAAATCAGTGATGGAAACGGCACTATTACCCTACGCTTTTTTAATTTTAATGCGGGCATGAAAAACAGCTT
TAGCGAAGGCAAACTCGTTCATGCTTATGGCGAAATTAAACGTGGAGGCAGTGGTTTAGAAATTGTTCATCCTGAATATC
AATTTCATGTGCCATCCCAACCACTTGAAATTGAAGCAAGCTTAACGCCTGTCTACCCAACAACGGACGGATTACGTCAA
AATACATTACGAAGTTTAACTGACCAAGCCTTAGAGCTATTAGATAAAGCAGCAGTTACTGAGCTTTTACCACAAGGTTT
ATACAATAACCAAATCACCCTTAATCAAGCGCTTCATATTATTCATCGTCCAGATCCATCGATAAATCTTGATGCATTTG
ATGAAGGCAAACACCCTGCTCAACAACGCTTAATTATGGAAGAGCTATTGGCTCAAAATTTATCTATGTTGTCTGTTCGT
AGTAAAGGACAACAAGAAGATGCATTACCCTTAGCAACACTGACTAATTTAAAGCAAAAACTATTAGCACAACTTCCTTT
TACTCCCACGAACGCTCAACAACGTGTTGTCGCTGAAATCGAACAAGATTTAGCAAAACCTCACCCAATGATGCGCTTAG
TACAAGGTGATGTAGGTTCAGGTAAAACCTTAGTTGCAGCATTAGCAGCGGTACAGGCTATCGAACACGGTTATCAAGTC
GCTTTAATGGCTCCGACGGAATTACTAGCAGAACAACACGCCGCTAACTTTGCACATTGGTTTGAATCGATGGGAATTAC
TGTTGGTTGGCTTGCAGGAAAACTAACAGGTAAAGCGAAAGAAAAAGAATTAGAGCGCATAGCCAGTGGCGAAGCGAAAA
TGATAGTGGGCACTCACGCACTGTTTCAACAAAATGTAGAGTTCCATCATCTTGCTCTGGTTATTATTGATGAACAACAT
CGTTTTGGTGTTGATCAACGCTTAGAGCTGCGTGAAAAAGGCCAAAAAAATGGAGCCTATCCACATCAATTAATCATGAC
TGCTACACCTATACCAAGAACGTTAGCCATGACGGCTTATGCTGACTTAGAAACCTCTGTTATTGATGAGCTTCCTCCGG
GTAGAACACCGATTCAAACGATAGCCGTTCCAGATACTCGTCGTGATGAGATAGTAAACAAAGTTCGTAGTGCGTGTATG
AACGACGGTAGACAAGCCTACTGGGTTTGTACTCTTATTGATGATTCAGAAGTATTAGAAGCCCAAGCCGCTTCCGACAC
CGCAGAAGCGTTACGCCTACAACTACCCGAACTAAACATTGGTTTAGTGCACGGTAGAATGAAGCCAAAAGAAAAACAGC
AAATCATGCAAGAGTTTAAAGAAGGAAATCTGCATTTGTTAGTGGCTACTACGGTTATCGAAGTGGGGGTAGATGTGCCT
AACTCAAGTTTAATGATCATTGAGAACCCTGAGCGCTTAGGGTTAGCACAACTGCACCAATTACGTGGGCGTGTGGGTCG
AGGTTCTGTTGCAAGTCACTGTGTACTCTTATATCACTCGCCATTATCAAAGACCGCACAAAAACGCTTAAGTGTTTTAC
GAGAGAGTAATGATGGCTTTGTGATTGCCCAACGTGATTTAGAAATTCGAGGGCCAGGTGAATTACTTGGAACCAAGCAA
ACAGGTTTAGCTGACTTTAAAATTGCTGATTTAGTTCGAGACCAACACCTAATACCAGAAGTACAACGCATTGCTCGTCA
CCTACATGATAACTATCCAAAAAATGCGAAAGCCATTATTTTACGTTGGTTAGGGGAACGAGACATTTACTCGAATGCGT
AA

Upstream 100 bases:

>100_bases
TGCTCTAAATCCAGGAGATAAAGGTATAATGACTTATCAAGGGCGTAAATTTCATCACTTTGCCTTAAAGCGAGATTAAA
GAAATACTAGGGAACCACTT

Downstream 100 bases:

>100_bases
ATAATTTCCTCCTCATAAATAGCAGATACAAAAAAGGTGAGTAACTACTCACCTTTTCTTTATTGCGATTAAACTAGCAA
TTAGTAGTAAGAGTGCTCAC

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MTNTMLSAIPLTSLAGVGAKVAEKLEKIGLVSIQDLLFHLPLRYEDRTRVYPMARVHSGLFAAVQGKVMSCDMQFGKRKM
LLVKISDGNGTITLRFFNFNAGMKNSFSEGKLVHAYGEIKRGGSGLEIVHPEYQFHVPSQPLEIEASLTPVYPTTDGLRQ
NTLRSLTDQALELLDKAAVTELLPQGLYNNQITLNQALHIIHRPDPSINLDAFDEGKHPAQQRLIMEELLAQNLSMLSVR
SKGQQEDALPLATLTNLKQKLLAQLPFTPTNAQQRVVAEIEQDLAKPHPMMRLVQGDVGSGKTLVAALAAVQAIEHGYQV
ALMAPTELLAEQHAANFAHWFESMGITVGWLAGKLTGKAKEKELERIASGEAKMIVGTHALFQQNVEFHHLALVIIDEQH
RFGVDQRLELREKGQKNGAYPHQLIMTATPIPRTLAMTAYADLETSVIDELPPGRTPIQTIAVPDTRRDEIVNKVRSACM
NDGRQAYWVCTLIDDSEVLEAQAASDTAEALRLQLPELNIGLVHGRMKPKEKQQIMQEFKEGNLHLLVATTVIEVGVDVP
NSSLMIIENPERLGLAQLHQLRGRVGRGSVASHCVLLYHSPLSKTAQKRLSVLRESNDGFVIAQRDLEIRGPGELLGTKQ
TGLADFKIADLVRDQHLIPEVQRIARHLHDNYPKNAKAIILRWLGERDIYSNA

Sequences:

>Translated_693_residues
MTNTMLSAIPLTSLAGVGAKVAEKLEKIGLVSIQDLLFHLPLRYEDRTRVYPMARVHSGLFAAVQGKVMSCDMQFGKRKM
LLVKISDGNGTITLRFFNFNAGMKNSFSEGKLVHAYGEIKRGGSGLEIVHPEYQFHVPSQPLEIEASLTPVYPTTDGLRQ
NTLRSLTDQALELLDKAAVTELLPQGLYNNQITLNQALHIIHRPDPSINLDAFDEGKHPAQQRLIMEELLAQNLSMLSVR
SKGQQEDALPLATLTNLKQKLLAQLPFTPTNAQQRVVAEIEQDLAKPHPMMRLVQGDVGSGKTLVAALAAVQAIEHGYQV
ALMAPTELLAEQHAANFAHWFESMGITVGWLAGKLTGKAKEKELERIASGEAKMIVGTHALFQQNVEFHHLALVIIDEQH
RFGVDQRLELREKGQKNGAYPHQLIMTATPIPRTLAMTAYADLETSVIDELPPGRTPIQTIAVPDTRRDEIVNKVRSACM
NDGRQAYWVCTLIDDSEVLEAQAASDTAEALRLQLPELNIGLVHGRMKPKEKQQIMQEFKEGNLHLLVATTVIEVGVDVP
NSSLMIIENPERLGLAQLHQLRGRVGRGSVASHCVLLYHSPLSKTAQKRLSVLRESNDGFVIAQRDLEIRGPGELLGTKQ
TGLADFKIADLVRDQHLIPEVQRIARHLHDNYPKNAKAIILRWLGERDIYSNA
>Mature_692_residues
TNTMLSAIPLTSLAGVGAKVAEKLEKIGLVSIQDLLFHLPLRYEDRTRVYPMARVHSGLFAAVQGKVMSCDMQFGKRKML
LVKISDGNGTITLRFFNFNAGMKNSFSEGKLVHAYGEIKRGGSGLEIVHPEYQFHVPSQPLEIEASLTPVYPTTDGLRQN
TLRSLTDQALELLDKAAVTELLPQGLYNNQITLNQALHIIHRPDPSINLDAFDEGKHPAQQRLIMEELLAQNLSMLSVRS
KGQQEDALPLATLTNLKQKLLAQLPFTPTNAQQRVVAEIEQDLAKPHPMMRLVQGDVGSGKTLVAALAAVQAIEHGYQVA
LMAPTELLAEQHAANFAHWFESMGITVGWLAGKLTGKAKEKELERIASGEAKMIVGTHALFQQNVEFHHLALVIIDEQHR
FGVDQRLELREKGQKNGAYPHQLIMTATPIPRTLAMTAYADLETSVIDELPPGRTPIQTIAVPDTRRDEIVNKVRSACMN
DGRQAYWVCTLIDDSEVLEAQAASDTAEALRLQLPELNIGLVHGRMKPKEKQQIMQEFKEGNLHLLVATTVIEVGVDVPN
SSLMIIENPERLGLAQLHQLRGRVGRGSVASHCVLLYHSPLSKTAQKRLSVLRESNDGFVIAQRDLEIRGPGELLGTKQT
GLADFKIADLVRDQHLIPEVQRIARHLHDNYPKNAKAIILRWLGERDIYSNA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=693, Percent_Identity=67.2438672438672, Blast_Score=953, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=389, Percent_Identity=37.7892030848329, Blast_Score=238, Evalue=8e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76839; Mature: 76708

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTMLSAIPLTSLAGVGAKVAEKLEKIGLVSIQDLLFHLPLRYEDRTRVYPMARVHSGL
CCCCHHHHCCHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHCCH
FAAVQGKVMSCDMQFGKRKMLLVKISDGNGTITLRFFNFNAGMKNSFSEGKLVHAYGEIK
HHHHCCCEEEEECCCCCCEEEEEEEECCCCEEEEEEEEECCCCCCCCCCCCEEEEEHHHH
RGGSGLEIVHPEYQFHVPSQPLEIEASLTPVYPTTDGLRQNTLRSLTDQALELLDKAAVT
CCCCCCEEECCCEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ELLPQGLYNNQITLNQALHIIHRPDPSINLDAFDEGKHPAQQRLIMEELLAQNLSMLSVR
HHHHCCCCCCEEEHHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHH
SKGQQEDALPLATLTNLKQKLLAQLPFTPTNAQQRVVAEIEQDLAKPHPMMRLVQGDVGS
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCC
GKTLVAALAAVQAIEHGYQVALMAPTELLAEQHAANFAHWFESMGITVGWLAGKLTGKAK
CHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCCCHH
EKELERIASGEAKMIVGTHALFQQNVEFHHLALVIIDEQHRFGVDQRLELREKGQKNGAY
HHHHHHHHCCCCEEEEEEHHHHHCCCCEEEEEEEEEECHHHCCCCHHHHHHHCCCCCCCC
PHQLIMTATPIPRTLAMTAYADLETSVIDELPPGRTPIQTIAVPDTRRDEIVNKVRSACM
CCEEEEECCCCCHHHHHHHHHCCHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHH
NDGRQAYWVCTLIDDSEVLEAQAASDTAEALRLQLPELNIGLVHGRMKPKEKQQIMQEFK
CCCCEEEEEEEEECCHHHHHHHHCCHHHHHHHEECCCCCEEEEECCCCCHHHHHHHHHHH
EGNLHLLVATTVIEVGVDVPNSSLMIIENPERLGLAQLHQLRGRVGRGSVASHCVLLYHS
CCCEEEEEEEEEHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCHHHEEEEEEEC
PLSKTAQKRLSVLRESNDGFVIAQRDLEIRGPGELLGTKQTGLADFKIADLVRDQHLIPE
CHHHHHHHHHHHHHCCCCCEEEEECCEEECCCHHHCCCCCCCCCCHHHHHHHHHHHCCHH
VQRIARHLHDNYPKNAKAIILRWLGERDIYSNA
HHHHHHHHHCCCCCCHHEEEEEECCCCCCCCCC
>Mature Secondary Structure 
TNTMLSAIPLTSLAGVGAKVAEKLEKIGLVSIQDLLFHLPLRYEDRTRVYPMARVHSGL
CCCHHHHCCHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHCCH
FAAVQGKVMSCDMQFGKRKMLLVKISDGNGTITLRFFNFNAGMKNSFSEGKLVHAYGEIK
HHHHCCCEEEEECCCCCCEEEEEEEECCCCEEEEEEEEECCCCCCCCCCCCEEEEEHHHH
RGGSGLEIVHPEYQFHVPSQPLEIEASLTPVYPTTDGLRQNTLRSLTDQALELLDKAAVT
CCCCCCEEECCCEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ELLPQGLYNNQITLNQALHIIHRPDPSINLDAFDEGKHPAQQRLIMEELLAQNLSMLSVR
HHHHCCCCCCEEEHHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHH
SKGQQEDALPLATLTNLKQKLLAQLPFTPTNAQQRVVAEIEQDLAKPHPMMRLVQGDVGS
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCC
GKTLVAALAAVQAIEHGYQVALMAPTELLAEQHAANFAHWFESMGITVGWLAGKLTGKAK
CHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCCCHH
EKELERIASGEAKMIVGTHALFQQNVEFHHLALVIIDEQHRFGVDQRLELREKGQKNGAY
HHHHHHHHCCCCEEEEEEHHHHHCCCCEEEEEEEEEECHHHCCCCHHHHHHHCCCCCCCC
PHQLIMTATPIPRTLAMTAYADLETSVIDELPPGRTPIQTIAVPDTRRDEIVNKVRSACM
CCEEEEECCCCCHHHHHHHHHCCHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHH
NDGRQAYWVCTLIDDSEVLEAQAASDTAEALRLQLPELNIGLVHGRMKPKEKQQIMQEFK
CCCCEEEEEEEEECCHHHHHHHHCCHHHHHHHEECCCCCEEEEECCCCCHHHHHHHHHHH
EGNLHLLVATTVIEVGVDVPNSSLMIIENPERLGLAQLHQLRGRVGRGSVASHCVLLYHS
CCCEEEEEEEEEHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCHHHEEEEEEEC
PLSKTAQKRLSVLRESNDGFVIAQRDLEIRGPGELLGTKQTGLADFKIADLVRDQHLIPE
CHHHHHHHHHHHHHCCCCCEEEEECCEEECCCHHHCCCCCCCCCCHHHHHHHHHHHCCHH
VQRIARHLHDNYPKNAKAIILRWLGERDIYSNA
HHHHHHHHHCCCCCCHHEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]