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The map label for this gene is rpe [H]

Identifier: 59712895

GI number: 59712895

Start: 2570493

End: 2571170

Strand: Reverse

Name: rpe [H]

Synonym: VF_2288

Alternate gene names: 59712895

Gene position: 2571170-2570493 (Counterclockwise)

Preceding gene: 59712896

Following gene: 59712894

Centisome position: 88.74

GC content: 40.12

Gene sequence:

>678_bases
ATGAAAGATTTTTTGATCGCACCATCTATTCTCTCTGCTGATTTCGCTCGTCTAGGCGAAGACGTTGAAAAAGTACTAGC
GTCAGGTGCTGATGTGGTTCACTTCGATGTAATGGATAACCACTATGTTCCAAATCTAACTTTTGGTGCTCCAATCTGTA
AAGCATTACGTGATTACGGCATCACAGCTCCTATTGATGTTCATTTAATGGTTAAGCCTGTTGATAGTATTGTTCCTGAG
TTTGCAAAAGCGGGTGCAACAATGATCACTTTCCATGTAGAAGCTTCAGAGCATATTGATCGTACACTTCAATTAATCAA
AGAGCATGGTTGTCAGGCTGGTGTAGTTTTAAACCCGGCAACACCATTATCATGCCTTGAATACATCATGGACAAAGTGG
ATATGATCTTACTAATGTCTGTAAACCCAGGCTTTGGCGGTCAATCTTTCATTCCAAATACACTTGATAAGCTACGTGCA
GTACGCAAAATGATTGACGAGTCAGGTCGTGATATTCGTCTTGAAATTGATGGTGGCGTAAAAGTGGATAACATCCGTGA
AATCGCAGAAGCGGGTGCAGATATGTTTGTTGCAGGTTCAGCTATCTTTAATCAACCAAACTACAAAGAAGTGATTGATG
AAATGCGTGCTGAATTAGCAAAAGTAAAAGGTAACTAA

Upstream 100 bases:

>100_bases
GACAGCCCCCAAAATATCAGGTAGAATTGCGCCGTCGATTTAATCGATTGCGCTATATCAATTTAGCGGTATCTAAATAA
TTACTAACCTGAGGCTCAAC

Downstream 100 bases:

>100_bases
GATTCATGTTTGAAGATATCAAACTGATCGCTTTTGATTTAGATGGGACGCTACTTGATAGCGTTCCTGATTTAGCTCGA
GCGGTGGATCTTGCAATGCA

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKDFLIAPSILSADFARLGEDVEKVLASGADVVHFDVMDNHYVPNLTFGAPICKALRDYGITAPIDVHLMVKPVDSIVPE
FAKAGATMITFHVEASEHIDRTLQLIKEHGCQAGVVLNPATPLSCLEYIMDKVDMILLMSVNPGFGGQSFIPNTLDKLRA
VRKMIDESGRDIRLEIDGGVKVDNIREIAEAGADMFVAGSAIFNQPNYKEVIDEMRAELAKVKGN

Sequences:

>Translated_225_residues
MKDFLIAPSILSADFARLGEDVEKVLASGADVVHFDVMDNHYVPNLTFGAPICKALRDYGITAPIDVHLMVKPVDSIVPE
FAKAGATMITFHVEASEHIDRTLQLIKEHGCQAGVVLNPATPLSCLEYIMDKVDMILLMSVNPGFGGQSFIPNTLDKLRA
VRKMIDESGRDIRLEIDGGVKVDNIREIAEAGADMFVAGSAIFNQPNYKEVIDEMRAELAKVKGN
>Mature_225_residues
MKDFLIAPSILSADFARLGEDVEKVLASGADVVHFDVMDNHYVPNLTFGAPICKALRDYGITAPIDVHLMVKPVDSIVPE
FAKAGATMITFHVEASEHIDRTLQLIKEHGCQAGVVLNPATPLSCLEYIMDKVDMILLMSVNPGFGGQSFIPNTLDKLRA
VRKMIDESGRDIRLEIDGGVKVDNIREIAEAGADMFVAGSAIFNQPNYKEVIDEMRAELAKVKGN

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=212, Percent_Identity=40.5660377358491, Blast_Score=167, Evalue=9e-42,
Organism=Homo sapiens, GI219879828, Length=212, Percent_Identity=39.622641509434, Blast_Score=157, Evalue=8e-39,
Organism=Homo sapiens, GI24307923, Length=168, Percent_Identity=33.9285714285714, Blast_Score=99, Evalue=4e-21,
Organism=Escherichia coli, GI1789788, Length=222, Percent_Identity=81.0810810810811, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI1790523, Length=211, Percent_Identity=36.9668246445498, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1790754, Length=211, Percent_Identity=26.5402843601896, Blast_Score=90, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17552948, Length=216, Percent_Identity=37.962962962963, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6322341, Length=229, Percent_Identity=37.9912663755458, Blast_Score=162, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24586301, Length=211, Percent_Identity=39.8104265402844, Blast_Score=167, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24585; Mature: 24585

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDFLIAPSILSADFARLGEDVEKVLASGADVVHFDVMDNHYVPNLTFGAPICKALRDYG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCC
ITAPIDVHLMVKPVDSIVPEFAKAGATMITFHVEASEHIDRTLQLIKEHGCQAGVVLNPA
CCCCEEEEEEECCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCEEECCC
TPLSCLEYIMDKVDMILLMSVNPGFGGQSFIPNTLDKLRAVRKMIDESGRDIRLEIDGGV
CHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCE
KVDNIREIAEAGADMFVAGSAIFNQPNYKEVIDEMRAELAKVKGN
EHHHHHHHHHCCCCEEEECHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKDFLIAPSILSADFARLGEDVEKVLASGADVVHFDVMDNHYVPNLTFGAPICKALRDYG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCC
ITAPIDVHLMVKPVDSIVPEFAKAGATMITFHVEASEHIDRTLQLIKEHGCQAGVVLNPA
CCCCEEEEEEECCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCEEECCC
TPLSCLEYIMDKVDMILLMSVNPGFGGQSFIPNTLDKLRAVRKMIDESGRDIRLEIDGGV
CHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCE
KVDNIREIAEAGADMFVAGSAIFNQPNYKEVIDEMRAELAKVKGN
EHHHHHHHHHCCCCEEEECHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]