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The map label for this gene is ilvH [H]

Identifier: 59712869

GI number: 59712869

Start: 2538518

End: 2539012

Strand: Reverse

Name: ilvH [H]

Synonym: VF_2262

Alternate gene names: 59712869

Gene position: 2539012-2538518 (Counterclockwise)

Preceding gene: 59712870

Following gene: 59712868

Centisome position: 87.63

GC content: 39.19

Gene sequence:

>495_bases
ATGAGACATATTATTTCACTATTATTAGAGAATGAACCGGGTTCTTTATCACGTGTTGTCGGCCTATTTTCTCAGCGTGG
ATACAACATTGAATCTTTAACGGTATCTCCAACTGAAGATCAGACATTGTCACGATTAAATATTACAACAGCCAGTGATG
CTATGGAGTTAGAGCAAATTCAAAAGCAACTCCATAAATTAATCGATGTCATCAAAGTTCAAGAAGTGACAGAGGCTGAT
TATGTTGAGCGTGAATTATTATTGGTAAAAGTAAAAGCAAGTGGTTTTGCTCGAGCGGAAGTTAAACGTACCGCTGATAT
TTTCCGAGGCCAAATTGTAGATGTAACAAGCTCGCTTTATACGATTCAATTAGCGGGTACCTCTGAAAAGTTAGATGCAT
TTATTTCAGCTGTATCAGAAGTGACTGATGTGGTGGAAGTTGCTCGAAGCGGCGTGGTTGGTATTGCGCGTGGAGACAAA
GCGTTAAAGGTATAA

Upstream 100 bases:

>100_bases
TTGTGGATATTAATGTTGATGAAACAGAGCACGTTTACCCAATGCAAATTAAAGGGGAAGCAATGGATAAAATGTGGCTA
AGTAAAACGGAGAGAACCTA

Downstream 100 bases:

>100_bases
TTGTATTTAACTAAGAGTCTTTATCCTATAAATAAAGCCCTTCTCAGAAGGGTTTTATTTTATCTTGTGTAATATAAAAT
GATTATATAGAATTTCGTAC

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: ALS-III; Acetohydroxy-acid synthase III small subunit; AHAS-III [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MRHIISLLLENEPGSLSRVVGLFSQRGYNIESLTVSPTEDQTLSRLNITTASDAMELEQIQKQLHKLIDVIKVQEVTEAD
YVERELLLVKVKASGFARAEVKRTADIFRGQIVDVTSSLYTIQLAGTSEKLDAFISAVSEVTDVVEVARSGVVGIARGDK
ALKV

Sequences:

>Translated_164_residues
MRHIISLLLENEPGSLSRVVGLFSQRGYNIESLTVSPTEDQTLSRLNITTASDAMELEQIQKQLHKLIDVIKVQEVTEAD
YVERELLLVKVKASGFARAEVKRTADIFRGQIVDVTSSLYTIQLAGTSEKLDAFISAVSEVTDVVEVARSGVVGIARGDK
ALKV
>Mature_164_residues
MRHIISLLLENEPGSLSRVVGLFSQRGYNIESLTVSPTEDQTLSRLNITTASDAMELEQIQKQLHKLIDVIKVQEVTEAD
YVERELLLVKVKASGFARAEVKRTADIFRGQIVDVTSSLYTIQLAGTSEKLDAFISAVSEVTDVVEVARSGVVGIARGDK
ALKV

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=163, Percent_Identity=65.6441717791411, Blast_Score=229, Evalue=5e-62,
Organism=Saccharomyces cerevisiae, GI6319837, Length=205, Percent_Identity=26.8292682926829, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 17987; Mature: 17987

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHIISLLLENEPGSLSRVVGLFSQRGYNIESLTVSPTEDQTLSRLNITTASDAMELEQI
CHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHEECCCCHHHHHHHHH
QKQLHKLIDVIKVQEVTEADYVERELLLVKVKASGFARAEVKRTADIFRGQIVDVTSSLY
HHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCHHEEECCCEE
TIQLAGTSEKLDAFISAVSEVTDVVEVARSGVVGIARGDKALKV
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCC
>Mature Secondary Structure
MRHIISLLLENEPGSLSRVVGLFSQRGYNIESLTVSPTEDQTLSRLNITTASDAMELEQI
CHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHEECCCCHHHHHHHHH
QKQLHKLIDVIKVQEVTEADYVERELLLVKVKASGFARAEVKRTADIFRGQIVDVTSSLY
HHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCHHEEECCCEE
TIQLAGTSEKLDAFISAVSEVTDVVEVARSGVVGIARGDKALKV
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6308579; 1630901; 9278503; 1851954; 2198273 [H]