Click here to switch to the map view.

The map label for this gene is csiR [H]

Identifier: 59712866

GI number: 59712866

Start: 2535525

End: 2536187

Strand: Direct

Name: csiR [H]

Synonym: VF_2259

Alternate gene names: 59712866

Gene position: 2535525-2536187 (Clockwise)

Preceding gene: 59712865

Following gene: 59712875

Centisome position: 87.51

GC content: 34.84

Gene sequence:

>663_bases
ATGTCTAGCTTAACTCTCACTGATAAAGTTTCAAAAATGATCCACCAAGATATTCTCTCTGGAAAATTAAAACCTGGTCA
GAAACTGGTCGTTGCTGAATTAAAAGAACGCTATAACGTAGGAGCATCCCCTATTCGTGAAGCTCTGGTTCAATTATCTT
GGAATAAATACGTCAAACTTGAACCTCAAAAAGGATGTTGGGTTGCGTCTATTTCCCTTAGTGAGCTTAAAGAATTATTT
GAAAGTTTACGTACTATAGGCCAAGTTTTATTAGCAAAGGCCATCACTAACGGTAATGAGAATTGGGAATTAAACGTACT
AACTAGTTTCCATAAATTAAACAAAATTAATCTACAAGATGCGAAAATAGAAGAGTTAAGAGAATGGGAAAATAGATACA
CTGATTTCCATAATTCACTTCTAGAAGGGGCTCAATCCCCTATTATGTATCAGTTCTATCAAGATATATCCCATCAAATC
ACACGCTACCGCCATTTAAATAATAACCCTCAAGTGATCAGTGAAACCTATGCTCAATATTTAGAAGAGCATGAAATTAT
GATGAAGCTCACTTTGTCACGTGATTCAGAACAAGCCATCAAATATTTAAATAATCATTACTCGAAAGCCAGTGATCTTA
TATCAACCTACTTTTCGGCTTAA

Upstream 100 bases:

>100_bases
GAGGGCTTTCGCCCTCTTTTTTTATGAAATTTTCTTGCCCAAAACAAACAATACGCTATACTATCAACCAATATTAACCG
CACGCCAAATTGTATATAAG

Downstream 100 bases:

>100_bases
GAGATAAAAAAACCAGGCAAATGCCTGGTTTTTTTTATTGAAAATTCACCACCCAAAAAACTCTTTATTATGGGTACTGA
TTAACAATACCATTAATAAA

Product: DNA-binding transcriptional regulator

Products: NA

Alternate protein names: Carbon starvation induced regulator [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MSSLTLTDKVSKMIHQDILSGKLKPGQKLVVAELKERYNVGASPIREALVQLSWNKYVKLEPQKGCWVASISLSELKELF
ESLRTIGQVLLAKAITNGNENWELNVLTSFHKLNKINLQDAKIEELREWENRYTDFHNSLLEGAQSPIMYQFYQDISHQI
TRYRHLNNNPQVISETYAQYLEEHEIMMKLTLSRDSEQAIKYLNNHYSKASDLISTYFSA

Sequences:

>Translated_220_residues
MSSLTLTDKVSKMIHQDILSGKLKPGQKLVVAELKERYNVGASPIREALVQLSWNKYVKLEPQKGCWVASISLSELKELF
ESLRTIGQVLLAKAITNGNENWELNVLTSFHKLNKINLQDAKIEELREWENRYTDFHNSLLEGAQSPIMYQFYQDISHQI
TRYRHLNNNPQVISETYAQYLEEHEIMMKLTLSRDSEQAIKYLNNHYSKASDLISTYFSA
>Mature_219_residues
SSLTLTDKVSKMIHQDILSGKLKPGQKLVVAELKERYNVGASPIREALVQLSWNKYVKLEPQKGCWVASISLSELKELFE
SLRTIGQVLLAKAITNGNENWELNVLTSFHKLNKINLQDAKIEELREWENRYTDFHNSLLEGAQSPIMYQFYQDISHQIT
RYRHLNNNPQVISETYAQYLEEHEIMMKLTLSRDSEQAIKYLNNHYSKASDLISTYFSA

Specific function: Modulates expression of csiD and lhgO in a temporal manner during entry into stationary phase or during the first few hours of carbon starvation [H]

COG id: COG1802

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082149, Length=191, Percent_Identity=32.4607329842932, Blast_Score=109, Evalue=1e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25512; Mature: 25381

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLTLTDKVSKMIHQDILSGKLKPGQKLVVAELKERYNVGASPIREALVQLSWNKYVKL
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEE
EPQKGCWVASISLSELKELFESLRTIGQVLLAKAITNGNENWELNVLTSFHKLNKINLQD
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCH
AKIEELREWENRYTDFHNSLLEGAQSPIMYQFYQDISHQITRYRHLNNNPQVISETYAQY
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LEEHEIMMKLTLSRDSEQAIKYLNNHYSKASDLISTYFSA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSLTLTDKVSKMIHQDILSGKLKPGQKLVVAELKERYNVGASPIREALVQLSWNKYVKL
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEE
EPQKGCWVASISLSELKELFESLRTIGQVLLAKAITNGNENWELNVLTSFHKLNKINLQD
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCH
AKIEELREWENRYTDFHNSLLEGAQSPIMYQFYQDISHQITRYRHLNNNPQVISETYAQY
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LEEHEIMMKLTLSRDSEQAIKYLNNHYSKASDLISTYFSA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8297211; 7984428 [H]