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The map label for this gene is gspA [H]

Identifier: 59712850

GI number: 59712850

Start: 2518844

End: 2520400

Strand: Reverse

Name: gspA [H]

Synonym: VF_2243

Alternate gene names: 59712850

Gene position: 2520400-2518844 (Counterclockwise)

Preceding gene: 59712852

Following gene: 59712849

Centisome position: 86.98

GC content: 39.11

Gene sequence:

>1557_bases
ATGTACCAAGATTTTTTTGGCTTTGATGAGTTGCCATTTTCAATGACCCCGAATGCACGATTTCTTTATCTAAGTGAGCG
TCATAAAGAAGCATTGAATTACCTATTATCTGGTTTAGGGCAAGGTGGTGGTTTTGCATTATTAACTGGGGAAGTAGGGA
CAGGTAAAACAACGGTTTCAAGAGCGTTATTTTCTCAGTTAGATGAAAAGGTGAATTTAGCTTTAATTTTAAACCCTATG
TTTAGTGCTCAAGAACTATTAGAAGCGATTTGCGATGAATTTGAAATTGCGTATTCTTCTCTTGCTTCATTAAAGCAGCT
AACCGATAACATTGTTCACTACTTAAAAAGTGAAAACGAAAAAGGCTACCAGACCATTGTTGCTATCGACGAAGCTCAGC
ATCTTGGCCCTGATGTTCTTGAGCAGCTGCGCTTATTAACAAACTTTGAAACCGATAGCGATAAGCTATTAAAAGTCTTA
TTAATTGGTCAGCCTGAACTGCAGCAAAAATTGCAGCAAACGAATTTACGACAATTAGCGCAGCGAATTACTGCGAGATA
CCACTTATTACCATTAACGCCACAAGAGATTGAACATTATATTGTCCACCGTTTAGGCGTAGCTGGTGGAGATACTTCGT
TATTTTCTTCATCATTAATTAAAAAAATTGCTCAGTACTCAAATGGGGTACCTCGTTTAGTTAACTTATTATGTGATAAA
GCATTGTGGGTGAGCTATCAAAATGGCAATCAAAAAATAGATCAAGCGGCGCTTAAAAAAGCAAGTGAGTTGGTTCTTGA
CTGGCAGGTTGTTTCTACTACTGAACATTCATCTATAAATATTCAAGCGCGTCGCTTTATTCCGTTAGCCGCTATCGGTG
TATCGGCTTTGTTGTGCTTTGGCATTTATTCTATGCTGCCTAGTTATTTAGATAAGCATTTTCCAATACAAGAACCAGTT
GTTGAAGCGCCTTTAGTGGGGTTTCATGATCAATCTGATGCATTTAAACAGTTACTTTCCGTATGGGGCTACTCTGTCAA
TTCATTCCAAGCTAACTGTACCAATGCAAAACGTGCGCAATTATATTGTTTAGATGACAACGGAACGTTAAATGATTTGC
TTGCTGTGAATCGTCCTGCGGTTGTTTGGTTACAAGAATATTCTGGCGAAGGTCTGCTAGCTATTGTATATCGTGTGAGC
TCTAAAGGTATTGAGTTGTTGCTTCCTTCTAAGCGTGTGGAAGTATCACACCAATGGTTTAGTCGCCACTGGAATGGGGC
ATACGTGCAATTATGGCAAAAGCCAATAATTACAGAGCGTGCGATGCGAAAAGGAGACGAAGGTGAAGCTATTTTTGCAT
TAAATCACCTACTTTCAACCGCGCTAGAGCAGCCTATGATTGAGTCAGATTTCTTCGATGAAAAAACGGAACAACAAGTG
AAGCAGTTTCAGGAAATTTTTGGTTTGAAAGAGGACGGCATTGCTGGTTCTAGTACTTTGATGTGGTTGGATAGTGTTAC
CAATGCAAATGCTCCGTTATTACAAGGAGAAGATTAA

Upstream 100 bases:

>100_bases
TCTTTACTTTCTTACATCCAATGATACCGTGCAAATAGAGTTTTTCGACTTTTTATTCCCATGCTTTTTTTGTTGAGCTG
ATTAGGATAGATTTAACCTT

Downstream 100 bases:

>100_bases
TATGTTGTCGAAATCGATATCTCCCGTACTCATTGGTGTGATTATTATTCTACCTCCGTTATCGCTTAGTGCTTATATAG
TTTGGCCTTATTATCAAGCT

Product: general secretion pathway protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MYQDFFGFDELPFSMTPNARFLYLSERHKEALNYLLSGLGQGGGFALLTGEVGTGKTTVSRALFSQLDEKVNLALILNPM
FSAQELLEAICDEFEIAYSSLASLKQLTDNIVHYLKSENEKGYQTIVAIDEAQHLGPDVLEQLRLLTNFETDSDKLLKVL
LIGQPELQQKLQQTNLRQLAQRITARYHLLPLTPQEIEHYIVHRLGVAGGDTSLFSSSLIKKIAQYSNGVPRLVNLLCDK
ALWVSYQNGNQKIDQAALKKASELVLDWQVVSTTEHSSINIQARRFIPLAAIGVSALLCFGIYSMLPSYLDKHFPIQEPV
VEAPLVGFHDQSDAFKQLLSVWGYSVNSFQANCTNAKRAQLYCLDDNGTLNDLLAVNRPAVVWLQEYSGEGLLAIVYRVS
SKGIELLLPSKRVEVSHQWFSRHWNGAYVQLWQKPIITERAMRKGDEGEAIFALNHLLSTALEQPMIESDFFDEKTEQQV
KQFQEIFGLKEDGIAGSSTLMWLDSVTNANAPLLQGED

Sequences:

>Translated_518_residues
MYQDFFGFDELPFSMTPNARFLYLSERHKEALNYLLSGLGQGGGFALLTGEVGTGKTTVSRALFSQLDEKVNLALILNPM
FSAQELLEAICDEFEIAYSSLASLKQLTDNIVHYLKSENEKGYQTIVAIDEAQHLGPDVLEQLRLLTNFETDSDKLLKVL
LIGQPELQQKLQQTNLRQLAQRITARYHLLPLTPQEIEHYIVHRLGVAGGDTSLFSSSLIKKIAQYSNGVPRLVNLLCDK
ALWVSYQNGNQKIDQAALKKASELVLDWQVVSTTEHSSINIQARRFIPLAAIGVSALLCFGIYSMLPSYLDKHFPIQEPV
VEAPLVGFHDQSDAFKQLLSVWGYSVNSFQANCTNAKRAQLYCLDDNGTLNDLLAVNRPAVVWLQEYSGEGLLAIVYRVS
SKGIELLLPSKRVEVSHQWFSRHWNGAYVQLWQKPIITERAMRKGDEGEAIFALNHLLSTALEQPMIESDFFDEKTEQQV
KQFQEIFGLKEDGIAGSSTLMWLDSVTNANAPLLQGED
>Mature_518_residues
MYQDFFGFDELPFSMTPNARFLYLSERHKEALNYLLSGLGQGGGFALLTGEVGTGKTTVSRALFSQLDEKVNLALILNPM
FSAQELLEAICDEFEIAYSSLASLKQLTDNIVHYLKSENEKGYQTIVAIDEAQHLGPDVLEQLRLLTNFETDSDKLLKVL
LIGQPELQQKLQQTNLRQLAQRITARYHLLPLTPQEIEHYIVHRLGVAGGDTSLFSSSLIKKIAQYSNGVPRLVNLLCDK
ALWVSYQNGNQKIDQAALKKASELVLDWQVVSTTEHSSINIQARRFIPLAAIGVSALLCFGIYSMLPSYLDKHFPIQEPV
VEAPLVGFHDQSDAFKQLLSVWGYSVNSFQANCTNAKRAQLYCLDDNGTLNDLLAVNRPAVVWLQEYSGEGLLAIVYRVS
SKGIELLLPSKRVEVSHQWFSRHWNGAYVQLWQKPIITERAMRKGDEGEAIFALNHLLSTALEQPMIESDFFDEKTEQQV
KQFQEIFGLKEDGIAGSSTLMWLDSVTNANAPLLQGED

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG3267

COG function: function code U; Type II secretory pathway, component ExeA (predicted ATPase)

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exeA family [H]

Homologues:

Organism=Escherichia coli, GI1789720, Length=499, Percent_Identity=23.2464929859719, Blast_Score=95, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00004 AAA; PF01471 PG_binding_1 [H]

EC number: NA

Molecular weight: Translated: 58106; Mature: 58106

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQDFFGFDELPFSMTPNARFLYLSERHKEALNYLLSGLGQGGGFALLTGEVGTGKTTVS
CCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
RALFSQLDEKVNLALILNPMFSAQELLEAICDEFEIAYSSLASLKQLTDNIVHYLKSENE
HHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KGYQTIVAIDEAQHLGPDVLEQLRLLTNFETDSDKLLKVLLIGQPELQQKLQQTNLRQLA
CCCEEEEEECCHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QRITARYHLLPLTPQEIEHYIVHRLGVAGGDTSLFSSSLIKKIAQYSNGVPRLVNLLCDK
HHHHHHEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCH
ALWVSYQNGNQKIDQAALKKASELVLDWQVVSTTEHSSINIQARRFIPLAAIGVSALLCF
HHEEEECCCCHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEHHHCCHHHHHHHHHHHHH
GIYSMLPSYLDKHFPIQEPVVEAPLVGFHDQSDAFKQLLSVWGYSVNSFQANCTNAKRAQ
HHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
LYCLDDNGTLNDLLAVNRPAVVWLQEYSGEGLLAIVYRVSSKGIELLLPSKRVEVSHQWF
EEEECCCCCHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHH
SRHWNGAYVQLWQKPIITERAMRKGDEGEAIFALNHLLSTALEQPMIESDFFDEKTEQQV
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
KQFQEIFGLKEDGIAGSSTLMWLDSVTNANAPLLQGED
HHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MYQDFFGFDELPFSMTPNARFLYLSERHKEALNYLLSGLGQGGGFALLTGEVGTGKTTVS
CCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
RALFSQLDEKVNLALILNPMFSAQELLEAICDEFEIAYSSLASLKQLTDNIVHYLKSENE
HHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KGYQTIVAIDEAQHLGPDVLEQLRLLTNFETDSDKLLKVLLIGQPELQQKLQQTNLRQLA
CCCEEEEEECCHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QRITARYHLLPLTPQEIEHYIVHRLGVAGGDTSLFSSSLIKKIAQYSNGVPRLVNLLCDK
HHHHHHEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCH
ALWVSYQNGNQKIDQAALKKASELVLDWQVVSTTEHSSINIQARRFIPLAAIGVSALLCF
HHEEEECCCCHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEHHHCCHHHHHHHHHHHHH
GIYSMLPSYLDKHFPIQEPVVEAPLVGFHDQSDAFKQLLSVWGYSVNSFQANCTNAKRAQ
HHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
LYCLDDNGTLNDLLAVNRPAVVWLQEYSGEGLLAIVYRVSSKGIELLLPSKRVEVSHQWF
EEEECCCCCHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHH
SRHWNGAYVQLWQKPIITERAMRKGDEGEAIFALNHLLSTALEQPMIESDFFDEKTEQQV
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
KQFQEIFGLKEDGIAGSSTLMWLDSVTNANAPLLQGED
HHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961440 [H]