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The map label for this gene is bacA

Identifier: 59712852

GI number: 59712852

Start: 2522023

End: 2522826

Strand: Reverse

Name: bacA

Synonym: VF_2245

Alternate gene names: 59712852

Gene position: 2522826-2522023 (Counterclockwise)

Preceding gene: 59712853

Following gene: 59712850

Centisome position: 87.07

GC content: 38.06

Gene sequence:

>804_bases
ATGACGTACTTTGAAGCTTTCTTTCTTGCTCTTCTGCAAGGATTCACAGAGTTTTTACCTATCTCAAGTTCAGCTCATTT
AATTTTACCCTCTGCAATTTTAGGCTGGTCAGATCAAGGTTTAGCTTTTGATGTCGCCGTTCACGTTGGAACATTAGCCG
CGGTGGTTATCTACTTTAGAAAAGAAGTGGTGACATTATTAACAGCTTGGGTCGGTTCTATTGTAAAAAAAGAGCATAAC
AAGGAATCAAATTTGGCTTGGTTAATCGTGTTAGCTACGATTCCAGCGGCTTTATTTGGCTTACTATTTAAAGATTTTAT
TGAAATATATTTACGTAGTGCATGGGTTATTGCTGCAACAACGATTGTTTTTGGTTTATTGCTTTGGTGGGTAGATAAAA
ATGCAACGTTAGCAAAAGATGAGTACCAAATGACGTGGAAAAAAGCGTTATTTTTAGGTATCGCTCAGGCAATGGCGATG
ATCCCAGGTACTTCTCGTTCAGGAATCACAATTACCGCAGCGCTGTATCTTGGATTTACTCGTGAGGCAGCGGCACGTTT
TTCTTTCCTAATGTCCATTCCAATTATTACACTTGCTGGATCTTATCTTGGTCTTAAATTAGCGATGAGTGATATTTCAA
TTCACTTAGGCTTATTAAGTACTGGTGTGATTGTCTCTTTTATTAGTGCCTATATCTGTATTCATTTCTTTTTGAAGCTG
ATTTCAAGTATGGGGATGATGCCGTTTGTTATCTACCGTATCTTATTAGGTTCAAGCCTATTGGTATGGTTAGCTTTGCA
CTAG

Upstream 100 bases:

>100_bases
ACCTGGTACAAAAACAACCATTAGTGAGATATGGAATCATTTCACTCACAATCAATCACTCAAACCCGCGTTAATTAACT
TAAGGTCTTAATGGAATATC

Downstream 100 bases:

>100_bases
AGACTAGAGACTAGAGACTAGAGACTAGAGACGATAGAGCAAGTATTGCTAGAGTGACAATGTTCTAGGCTTTAGGATAT
TATGCTTGCAGGTTTTGGGT

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MTYFEAFFLALLQGFTEFLPISSSAHLILPSAILGWSDQGLAFDVAVHVGTLAAVVIYFRKEVVTLLTAWVGSIVKKEHN
KESNLAWLIVLATIPAALFGLLFKDFIEIYLRSAWVIAATTIVFGLLLWWVDKNATLAKDEYQMTWKKALFLGIAQAMAM
IPGTSRSGITITAALYLGFTREAAARFSFLMSIPIITLAGSYLGLKLAMSDISIHLGLLSTGVIVSFISAYICIHFFLKL
ISSMGMMPFVIYRILLGSSLLVWLALH

Sequences:

>Translated_267_residues
MTYFEAFFLALLQGFTEFLPISSSAHLILPSAILGWSDQGLAFDVAVHVGTLAAVVIYFRKEVVTLLTAWVGSIVKKEHN
KESNLAWLIVLATIPAALFGLLFKDFIEIYLRSAWVIAATTIVFGLLLWWVDKNATLAKDEYQMTWKKALFLGIAQAMAM
IPGTSRSGITITAALYLGFTREAAARFSFLMSIPIITLAGSYLGLKLAMSDISIHLGLLSTGVIVSFISAYICIHFFLKL
ISSMGMMPFVIYRILLGSSLLVWLALH
>Mature_266_residues
TYFEAFFLALLQGFTEFLPISSSAHLILPSAILGWSDQGLAFDVAVHVGTLAAVVIYFRKEVVTLLTAWVGSIVKKEHNK
ESNLAWLIVLATIPAALFGLLFKDFIEIYLRSAWVIAATTIVFGLLLWWVDKNATLAKDEYQMTWKKALFLGIAQAMAMI
PGTSRSGITITAALYLGFTREAAARFSFLMSIPIITLAGSYLGLKLAMSDISIHLGLLSTGVIVSFISAYICIHFFLKLI
SSMGMMPFVIYRILLGSSLLVWLALH

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=263, Percent_Identity=33.4600760456274, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_VIBF1 (Q5E2K6)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_205628.1
- STRING:   Q5E2K6
- GeneID:   3279448
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_2245
- NMPDR:   fig|312309.3.peg.2244
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   HSMYWFV
- PhylomeDB:   Q5E2K6
- ProtClustDB:   PRK00281
- BioCyc:   VFIS312309:VF2245-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29425; Mature: 29293

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12d2932c)-; HASH(0x131eddb8)-; HASH(0x131ead38)-; HASH(0x131eab4c)-; HASH(0x131ee064)-; HASH(0x131ca760)-; HASH(0x131ca778)-; HASH(0x1317e17c)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYFEAFFLALLQGFTEFLPISSSAHLILPSAILGWSDQGLAFDVAVHVGTLAAVVIYFR
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHH
KEVVTLLTAWVGSIVKKEHNKESNLAWLIVLATIPAALFGLLFKDFIEIYLRSAWVIAAT
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIVFGLLLWWVDKNATLAKDEYQMTWKKALFLGIAQAMAMIPGTSRSGITITAALYLGFT
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHH
REAAARFSFLMSIPIITLAGSYLGLKLAMSDISIHLGLLSTGVIVSFISAYICIHFFLKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISSMGMMPFVIYRILLGSSLLVWLALH
HHHCCHHHHHHHHHHHCCHHHHHEECH
>Mature Secondary Structure 
TYFEAFFLALLQGFTEFLPISSSAHLILPSAILGWSDQGLAFDVAVHVGTLAAVVIYFR
CHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHH
KEVVTLLTAWVGSIVKKEHNKESNLAWLIVLATIPAALFGLLFKDFIEIYLRSAWVIAAT
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIVFGLLLWWVDKNATLAKDEYQMTWKKALFLGIAQAMAMIPGTSRSGITITAALYLGFT
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHH
REAAARFSFLMSIPIITLAGSYLGLKLAMSDISIHLGLLSTGVIVSFISAYICIHFFLKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISSMGMMPFVIYRILLGSSLLVWLALH
HHHCCHHHHHHHHHHHCCHHHHHEECH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA