Click here to switch to the map view.

The map label for this gene is litR [H]

Identifier: 59712784

GI number: 59712784

Start: 2446537

End: 2447142

Strand: Direct

Name: litR [H]

Synonym: VF_2177

Alternate gene names: 59712784

Gene position: 2446537-2447142 (Clockwise)

Preceding gene: 59712781

Following gene: 59712791

Centisome position: 84.44

GC content: 35.31

Gene sequence:

>606_bases
ATGGATACAATCCAAAAAAGGCCTAGAACAAGGCTATCTCCAGAAAAGCGCAAAGAACAATTACTTGATATCGCAATTGA
AGTGTTTTCACAACGTGGCATTGGTCGCGGTGGTCATGCTGATATTGCAGAAATCGCTCAGGTCTCTGTCGCTACCGTGT
TTAATTACTTCCCAACAAGAGAAGATCTTGTTGATGATGTATTAAATAAAGTCGAAAACGAATTTCACCAATTCATCAAT
AACTCAATTTCTCTTGATCTTGATGTTCGTTCTAACCTTAATACTCTTCTTCTGAATATCATTGACAGTGTTCAAACTGG
TAATAAGTGGATCAAAGTATGGTTTGAATGGAGTACCTCTACTCGTGATGAAGTATGGCCTCTTTTCTTAAGTACTCACT
CAAATACAAATCAAGTTATCAAAACTATGTTTGAAGAAGGTATTGAACGTAACGAAGTATGTAACGATCATACCCCTGAA
AACCTAACAAAAATGCTTCATGGTATTTGTTACTCTGTTTTCATTCAGGCTAACCGTAATAGTTCATCTGAAGAAATGGA
AGAAACGGCAAATTGTTTCTTAAATATGTTGTGTATTTATAAATAA

Upstream 100 bases:

>100_bases
TAACTGTTGAATATATAAGCAGCCTTATGTAAAGTTATTGAGAATAATAATAATAAAACCCTATATAAAATAATAATTTG
TTGGCAAGGATATAAATATA

Downstream 100 bases:

>100_bases
TTTCAGGATTCATGAAATGATAATAATAAAAAACCGCTGATTTCTCAGCGGTTTTTTATATCTTAACAAATGCGTTGTTA
ATCAGAATTATTTTTTCTTT

Product: quorum sensing transcriptional regulator LitR (HapR)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MDTIQKRPRTRLSPEKRKEQLLDIAIEVFSQRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNKVENEFHQFIN
NSISLDLDVRSNLNTLLLNIIDSVQTGNKWIKVWFEWSTSTRDEVWPLFLSTHSNTNQVIKTMFEEGIERNEVCNDHTPE
NLTKMLHGICYSVFIQANRNSSSEEMEETANCFLNMLCIYK

Sequences:

>Translated_201_residues
MDTIQKRPRTRLSPEKRKEQLLDIAIEVFSQRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNKVENEFHQFIN
NSISLDLDVRSNLNTLLLNIIDSVQTGNKWIKVWFEWSTSTRDEVWPLFLSTHSNTNQVIKTMFEEGIERNEVCNDHTPE
NLTKMLHGICYSVFIQANRNSSSEEMEETANCFLNMLCIYK
>Mature_201_residues
MDTIQKRPRTRLSPEKRKEQLLDIAIEVFSQRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNKVENEFHQFIN
NSISLDLDVRSNLNTLLLNIIDSVQTGNKWIKVWFEWSTSTRDEVWPLFLSTHSNTNQVIKTMFEEGIERNEVCNDHTPE
NLTKMLHGICYSVFIQANRNSSSEEMEETANCFLNMLCIYK

Specific function: Regulatory protein of bacterial bioluminescence. It probably binds the autoinducer molecule and potentiates the transcription of the bioluminescence operon [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 23246; Mature: 23246

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTIQKRPRTRLSPEKRKEQLLDIAIEVFSQRGIGRGGHADIAEIAQVSVATVFNYFPTR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCH
EDLVDDVLNKVENEFHQFINNSISLDLDVRSNLNTLLLNIIDSVQTGNKWIKVWFEWSTS
HHHHHHHHHHHHHHHHHHHCCCCEEEEECHHCHHHHHHHHHHHHHCCCEEEEEEEEECCC
TRDEVWPLFLSTHSNTNQVIKTMFEEGIERNEVCNDHTPENLTKMLHGICYSVFIQANRN
CCCHHHHHHEECCCCHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
SSSEEMEETANCFLNMLCIYK
CCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDTIQKRPRTRLSPEKRKEQLLDIAIEVFSQRGIGRGGHADIAEIAQVSVATVFNYFPTR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCH
EDLVDDVLNKVENEFHQFINNSISLDLDVRSNLNTLLLNIIDSVQTGNKWIKVWFEWSTS
HHHHHHHHHHHHHHHHHHHCCCCEEEEECHHCHHHHHHHHHHHHHCCCEEEEEEEEECCC
TRDEVWPLFLSTHSNTNQVIKTMFEEGIERNEVCNDHTPENLTKMLHGICYSVFIQANRN
CCCHHHHHHEECCCCHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
SSSEEMEETANCFLNMLCIYK
CCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2160932; 8344950 [H]