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The map label for this gene is cobD [H]

Identifier: 59712736

GI number: 59712736

Start: 2375127

End: 2376080

Strand: Direct

Name: cobD [H]

Synonym: VF_2129

Alternate gene names: 59712736

Gene position: 2375127-2376080 (Clockwise)

Preceding gene: 59712735

Following gene: 59712737

Centisome position: 81.97

GC content: 35.53

Gene sequence:

>954_bases
ATGCTAGATAAATTAACTCTCTTTATTTCTGATTACTCTTTACTGGTATTATGGGGGGCTTTAATTTTTCACCTCATCAT
TCCTATTTCCCCCCAGTTTCATCCAATGTCTTTTTGGCACAAATTTGCTTTAATCCTAGCTGAAAAGGTAAATACATCTC
GTCCTTATCAACAACGTTTATTATCAGGTTCCCTTGCATGGGCATTAATGATTATTCCTGTAATCATTGTATATATTGCA
GCAGTGCCTCTTATTTGGAACATCCCTCTTTTTAATCTTGGGTTACTATTGTTATCGCTAGAATGGCGTGGTGTCGAAAA
ACTGTGTAAAGATACGATTCATGCCATAAATAAAGAAGATAAAAGCAGAGCAAAAGAAACTCTCAAGCATTGGGTAAATA
GAGACGTAGAACCATTATCATTACTAGGTTTAGGTAAAGCATCTAGTGAAACAATCATTTTGGCTTATGCGAGAACCGTT
ATTGGGGTCTTATTTTGGTATGGTATTGCTGGTGGAATTGGAGCTTTTGTTTATCGATTATCATTAGAGTTAGCAAGAGC
GTGGTCTCCATCTAGAGATTCATTTCGACCTTTTGGCATCCCTGCTCTACGTATTCAATATATTTTAGATTTTCTCCCAC
TTAAGCTTTTCACCCTCCTTTGTTTTATAGGCAAAAACATCCGTCATTCTTTTCAACAGTTACAATTACAAAAAAAGAAC
TGGGCCAATAAAAATAATGCAGGGCTACTTATTATTATTGGAAAAAAGTTTGAGCTTTCTTTAGGTGGACCTGTTATTTA
TCAAGGAAAGAAAATCAACCGAGCAAAACTAGGTGGAAAAATAGCCCCATCAGCGATTCATTTAGCACAAATTCACCGTT
TTTTAAGCTGGAGAATAGCGATTTGGCTCATTCTTCAAAGCTCAATAATGGTCATATTAAAACAAGGTTTATAA

Upstream 100 bases:

>100_bases
AATGGTATTAAACATGGTTACTTTATTAAAGTAATCTTATTTAATTGAGTCAGTTTCTCTGACTCAATTTTATCTTCTTT
TATATATAAAGAATCACCTC

Downstream 100 bases:

>100_bases
CTTTCTTTCAACAACATCATGCAGTAAGTCATAGAGGACAAGATGTTAATCTATACAATTGATATGTTTGGTACTGCCAT
TTTCGCCATTTCAGGAGTGT

Product: adenosylcobinamide-phosphate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MLDKLTLFISDYSLLVLWGALIFHLIIPISPQFHPMSFWHKFALILAEKVNTSRPYQQRLLSGSLAWALMIIPVIIVYIA
AVPLIWNIPLFNLGLLLLSLEWRGVEKLCKDTIHAINKEDKSRAKETLKHWVNRDVEPLSLLGLGKASSETIILAYARTV
IGVLFWYGIAGGIGAFVYRLSLELARAWSPSRDSFRPFGIPALRIQYILDFLPLKLFTLLCFIGKNIRHSFQQLQLQKKN
WANKNNAGLLIIIGKKFELSLGGPVIYQGKKINRAKLGGKIAPSAIHLAQIHRFLSWRIAIWLILQSSIMVILKQGL

Sequences:

>Translated_317_residues
MLDKLTLFISDYSLLVLWGALIFHLIIPISPQFHPMSFWHKFALILAEKVNTSRPYQQRLLSGSLAWALMIIPVIIVYIA
AVPLIWNIPLFNLGLLLLSLEWRGVEKLCKDTIHAINKEDKSRAKETLKHWVNRDVEPLSLLGLGKASSETIILAYARTV
IGVLFWYGIAGGIGAFVYRLSLELARAWSPSRDSFRPFGIPALRIQYILDFLPLKLFTLLCFIGKNIRHSFQQLQLQKKN
WANKNNAGLLIIIGKKFELSLGGPVIYQGKKINRAKLGGKIAPSAIHLAQIHRFLSWRIAIWLILQSSIMVILKQGL
>Mature_317_residues
MLDKLTLFISDYSLLVLWGALIFHLIIPISPQFHPMSFWHKFALILAEKVNTSRPYQQRLLSGSLAWALMIIPVIIVYIA
AVPLIWNIPLFNLGLLLLSLEWRGVEKLCKDTIHAINKEDKSRAKETLKHWVNRDVEPLSLLGLGKASSETIILAYARTV
IGVLFWYGIAGGIGAFVYRLSLELARAWSPSRDSFRPFGIPALRIQYILDFLPLKLFTLLCFIGKNIRHSFQQLQLQKKN
WANKNNAGLLIIIGKKFELSLGGPVIYQGKKINRAKLGGKIAPSAIHLAQIHRFLSWRIAIWLILQSSIMVILKQGL

Specific function: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group [H]

COG id: COG1270

COG function: function code H; Cobalamin biosynthesis protein CobD/CbiB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobD/CbiB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004485 [H]

Pfam domain/function: PF03186 CobD_Cbib [H]

EC number: NA

Molecular weight: Translated: 35952; Mature: 35952

Theoretical pI: Translated: 10.80; Mature: 10.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKLTLFISDYSLLVLWGALIFHLIIPISPQFHPMSFWHKFALILAEKVNTSRPYQQRL
CCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
LSGSLAWALMIIPVIIVYIAAVPLIWNIPLFNLGLLLLSLEWRGVEKLCKDTIHAINKED
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHH
KSRAKETLKHWVNRDVEPLSLLGLGKASSETIILAYARTVIGVLFWYGIAGGIGAFVYRL
HHHHHHHHHHHHCCCCCCHHHEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLELARAWSPSRDSFRPFGIPALRIQYILDFLPLKLFTLLCFIGKNIRHSFQQLQLQKKN
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WANKNNAGLLIIIGKKFELSLGGPVIYQGKKINRAKLGGKIAPSAIHLAQIHRFLSWRIA
CCCCCCCEEEEEECCEEEEECCCCEEECCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHH
IWLILQSSIMVILKQGL
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDKLTLFISDYSLLVLWGALIFHLIIPISPQFHPMSFWHKFALILAEKVNTSRPYQQRL
CCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
LSGSLAWALMIIPVIIVYIAAVPLIWNIPLFNLGLLLLSLEWRGVEKLCKDTIHAINKED
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHH
KSRAKETLKHWVNRDVEPLSLLGLGKASSETIILAYARTVIGVLFWYGIAGGIGAFVYRL
HHHHHHHHHHHHCCCCCCHHHEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLELARAWSPSRDSFRPFGIPALRIQYILDFLPLKLFTLLCFIGKNIRHSFQQLQLQKKN
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WANKNNAGLLIIIGKKFELSLGGPVIYQGKKINRAKLGGKIAPSAIHLAQIHRFLSWRIA
CCCCCCCEEEEEECCEEEEECCCCEEECCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHH
IWLILQSSIMVILKQGL
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]