Click here to switch to the map view.

The map label for this gene is arcB [H]

Identifier: 59712729

GI number: 59712729

Start: 2357687

End: 2360053

Strand: Reverse

Name: arcB [H]

Synonym: VF_2122

Alternate gene names: 59712729

Gene position: 2360053-2357687 (Counterclockwise)

Preceding gene: 59712730

Following gene: 59712728

Centisome position: 81.45

GC content: 37.14

Gene sequence:

>2367_bases
ATGAAGCAGTTAAAAATTCTCGCGCAATTTTATGTCGATCTTATGGTAAGGCTCGGCATTGTCCGTTTTAGTCTATTACT
TGCCATTGCCTTAGTTGCACTCGCCGTCATTGTTCAGGTTGGTGTGACGCTTGTTCTGAGCGGTGAAGTGAATGATCTCG
ATATTATTCGTTCTGTATTCTTTGGTTTATTGATCACGCCTTGGGCAGTGTTCTTTTTATCTGTAGTGGTTGAACATTTA
GAAGATTCTCGTCAACGATTATCTAAATTGGTGAGTAAGCTTGAAGAGATGCGTACTCGAGATCTTGATTTAAATAAAAA
GCTTAAAGGAAATGTTAAAAAGCTAAATCAAGAAATTGAAGAACGTGAAAAAGCAGAAGAAGCACGACAAGAAGCGATGG
AAGATCTCGAAAATGAAGTATTCCAACGTGAGAAAGCACAATTAGAATTAGCAGAACAAACCGCATTATTACGATCTTAC
TTAGATACCTCTCCCGATATTATTTATTACCGAAACGATCTTGGTCTATTCTCTGGTTGTAATAAAGCCATGGAGCAGCT
GACTGGCAAGTTAGAAAAAGAGCTGATTGGCCTCTCTCCTAAAGATGTATACGATGCCGAAGTTGCTGCAAAAGTTATTG
ATACGGATAGGCAAGTTTTACAAGAAAACCAAGCATTAACCTATGAACAATGGCTTGATTACCCTGATGGTCGTAAAGCG
TGTTTTGAATTGAATAAAATTCCATTTTATAGCAAAGATGGTCGTCGTTTAGGCTTGGTTGGTTTTGGACGAAATATTAC
TGAACGTAAAGAATATGAAGATGCATTACAAAAAGCGAGCCGTGATAAAACGACCTTTATTTCAACCATCAGTCATGAAT
TACGCACGCCATTAAATGGTATTGTCGGTTTAAGCCGAATGTTGTTGGACTCTCGTTTAGATGATGAACAACATAATTAC
ATGAGAACCATTAATGTCAGTGCCATTACATTAGGCAATATTTTTAACGATATTATCGATATGGATAAGTTCGATCGCCG
CAAATTAGAGCTTTTCCCTAAACCGCTAGATTTCATTAGTTTTGTCACTGAAATGGAAAACATTTCGGGGCTTATGGCTG
AACAAAAAGGGTTACGTTTTGATCTTGAGCGCTTGACCGACTTACCTCCTCATATCAGTGTAGATAGCACTCGATTAAGA
CAGGTGTTATGGAACCTTGTTGGTAATGCCACCAAATTTACCAAAGAAGGTGGGGTTGTTATGTCTGTGAGTGCGGACAT
ACATCAGGATAGCGCAGAGATCACCTTTGAGATAGAAGACACCGGAATCGGTATTCCTGAAGAAGAATTAGAAAATGTTT
TTGCTATGTATTATCAAGTTAAGCAAGGCAAGGATAATTTACATGCTGTAGGTACTGGGATTGGACTAGCGGTATCAAAA
GAGCTGATAAATTTAATGGGTGGTGATATCACGGTTACAAGTGAAGTCGATTTTGGTAGTACTTTTATAGTGACAATTAA
TGTTCCATTAGTTGATCATGTAGAAGAAGAAGAGGCAATGCCTGAGACAAAAAGCTCAAAGTCATTACGCATTTTTATGC
TTGAAGATATTGAGTTAAATGTCACAGTAGCGTGCTCTTTATTAGAAAGCTTAGGTCATACCGTTGATGTTGCAATGTGT
GGTGAAGATGCGATAAAGCAATTTGATCCAACTAAGTATGATCTAGCGCTTTTAGATATTCAATTGCCTGATATGACAGG
GTTTGATGTCGCTAAAATATTACGTGATAAGTTTGATAATTTACCACCATTAATTGCATTAACGGCTAATTTACTTAAAG
AAAAAGATGAGTATTTTAAAAATGGAATGGATGAAGCGTTAAGTAAACCACTGAGTGTTAAAGCGTTAACCGAGGTACTT
GAGCAATTTTCAATGTCAGAGAAGAAGACAGACATTCCAAGCGTACCACAAGAACAAGAAGTCTCTTCTGAGCCTACTGA
AAATGATCAGCTAATTGAATGTTTACTCGATCTAGAAATGTTAGAGTCTTATATTGAGATCGTAGGAACAAAACCTATTT
ATGCAAATATCGAAATGTTTGAAAAAAGTATGAAAGAATACATTCAAATACTTGATACAAACATGACGGCCAGAGACCAA
GATGGCATTGTGTTTGAAACGCATAAAATGAAAGGTGCAGCAGGCTCGATTGGGTTAAAACATATTCAACAAGTCGCACA
GAAAGCACAATCACCAGATTTACCTGCGTGGTGGGAAAATATTGATGATTGGGTTGAAGAAATCAAAAATGAATACGAAC
ATGATATTCAAATTTTAAAAAGCTGGTTAGAGCAGCAAGATAAGTAA

Upstream 100 bases:

>100_bases
GATTGATCAACCTTTCAAATATACTGCTCCAGTGCTGAAAAAATAACTCAAATGCATCTAACCCTGATATTATTTATGTG
AATATTATCAGGGTATGTTT

Downstream 100 bases:

>100_bases
GGAATAATATGAAGAAGGTACTATTTGCCGCAACACTAATAACAGCTTTATCTGGTTGTCAAATGACGAATCAATCAGAA
GCGGATTGGAAACAAGATAA

Product: aerobic respiration control sensor protein ArcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 788; Mature: 788

Protein sequence:

>788_residues
MKQLKILAQFYVDLMVRLGIVRFSLLLAIALVALAVIVQVGVTLVLSGEVNDLDIIRSVFFGLLITPWAVFFLSVVVEHL
EDSRQRLSKLVSKLEEMRTRDLDLNKKLKGNVKKLNQEIEEREKAEEARQEAMEDLENEVFQREKAQLELAEQTALLRSY
LDTSPDIIYYRNDLGLFSGCNKAMEQLTGKLEKELIGLSPKDVYDAEVAAKVIDTDRQVLQENQALTYEQWLDYPDGRKA
CFELNKIPFYSKDGRRLGLVGFGRNITERKEYEDALQKASRDKTTFISTISHELRTPLNGIVGLSRMLLDSRLDDEQHNY
MRTINVSAITLGNIFNDIIDMDKFDRRKLELFPKPLDFISFVTEMENISGLMAEQKGLRFDLERLTDLPPHISVDSTRLR
QVLWNLVGNATKFTKEGGVVMSVSADIHQDSAEITFEIEDTGIGIPEEELENVFAMYYQVKQGKDNLHAVGTGIGLAVSK
ELINLMGGDITVTSEVDFGSTFIVTINVPLVDHVEEEEAMPETKSSKSLRIFMLEDIELNVTVACSLLESLGHTVDVAMC
GEDAIKQFDPTKYDLALLDIQLPDMTGFDVAKILRDKFDNLPPLIALTANLLKEKDEYFKNGMDEALSKPLSVKALTEVL
EQFSMSEKKTDIPSVPQEQEVSSEPTENDQLIECLLDLEMLESYIEIVGTKPIYANIEMFEKSMKEYIQILDTNMTARDQ
DGIVFETHKMKGAAGSIGLKHIQQVAQKAQSPDLPAWWENIDDWVEEIKNEYEHDIQILKSWLEQQDK

Sequences:

>Translated_788_residues
MKQLKILAQFYVDLMVRLGIVRFSLLLAIALVALAVIVQVGVTLVLSGEVNDLDIIRSVFFGLLITPWAVFFLSVVVEHL
EDSRQRLSKLVSKLEEMRTRDLDLNKKLKGNVKKLNQEIEEREKAEEARQEAMEDLENEVFQREKAQLELAEQTALLRSY
LDTSPDIIYYRNDLGLFSGCNKAMEQLTGKLEKELIGLSPKDVYDAEVAAKVIDTDRQVLQENQALTYEQWLDYPDGRKA
CFELNKIPFYSKDGRRLGLVGFGRNITERKEYEDALQKASRDKTTFISTISHELRTPLNGIVGLSRMLLDSRLDDEQHNY
MRTINVSAITLGNIFNDIIDMDKFDRRKLELFPKPLDFISFVTEMENISGLMAEQKGLRFDLERLTDLPPHISVDSTRLR
QVLWNLVGNATKFTKEGGVVMSVSADIHQDSAEITFEIEDTGIGIPEEELENVFAMYYQVKQGKDNLHAVGTGIGLAVSK
ELINLMGGDITVTSEVDFGSTFIVTINVPLVDHVEEEEAMPETKSSKSLRIFMLEDIELNVTVACSLLESLGHTVDVAMC
GEDAIKQFDPTKYDLALLDIQLPDMTGFDVAKILRDKFDNLPPLIALTANLLKEKDEYFKNGMDEALSKPLSVKALTEVL
EQFSMSEKKTDIPSVPQEQEVSSEPTENDQLIECLLDLEMLESYIEIVGTKPIYANIEMFEKSMKEYIQILDTNMTARDQ
DGIVFETHKMKGAAGSIGLKHIQQVAQKAQSPDLPAWWENIDDWVEEIKNEYEHDIQILKSWLEQQDK
>Mature_788_residues
MKQLKILAQFYVDLMVRLGIVRFSLLLAIALVALAVIVQVGVTLVLSGEVNDLDIIRSVFFGLLITPWAVFFLSVVVEHL
EDSRQRLSKLVSKLEEMRTRDLDLNKKLKGNVKKLNQEIEEREKAEEARQEAMEDLENEVFQREKAQLELAEQTALLRSY
LDTSPDIIYYRNDLGLFSGCNKAMEQLTGKLEKELIGLSPKDVYDAEVAAKVIDTDRQVLQENQALTYEQWLDYPDGRKA
CFELNKIPFYSKDGRRLGLVGFGRNITERKEYEDALQKASRDKTTFISTISHELRTPLNGIVGLSRMLLDSRLDDEQHNY
MRTINVSAITLGNIFNDIIDMDKFDRRKLELFPKPLDFISFVTEMENISGLMAEQKGLRFDLERLTDLPPHISVDSTRLR
QVLWNLVGNATKFTKEGGVVMSVSADIHQDSAEITFEIEDTGIGIPEEELENVFAMYYQVKQGKDNLHAVGTGIGLAVSK
ELINLMGGDITVTSEVDFGSTFIVTINVPLVDHVEEEEAMPETKSSKSLRIFMLEDIELNVTVACSLLESLGHTVDVAMC
GEDAIKQFDPTKYDLALLDIQLPDMTGFDVAKILRDKFDNLPPLIALTANLLKEKDEYFKNGMDEALSKPLSVKALTEVL
EQFSMSEKKTDIPSVPQEQEVSSEPTENDQLIECLLDLEMLESYIEIVGTKPIYANIEMFEKSMKEYIQILDTNMTARDQ
DGIVFETHKMKGAAGSIGLKHIQQVAQKAQSPDLPAWWENIDDWVEEIKNEYEHDIQILKSWLEQQDK

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=794, Percent_Identity=57.9345088161209, Blast_Score=922, Evalue=0.0,
Organism=Escherichia coli, GI1788713, Length=534, Percent_Identity=29.9625468164794, Blast_Score=179, Evalue=8e-46,
Organism=Escherichia coli, GI1789149, Length=383, Percent_Identity=31.8537859007833, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI87081816, Length=540, Percent_Identity=25.7407407407407, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=35.9183673469388, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1788549, Length=347, Percent_Identity=27.0893371757925, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1788393, Length=247, Percent_Identity=26.7206477732794, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1786912, Length=257, Percent_Identity=24.5136186770428, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1786600, Length=376, Percent_Identity=21.8085106382979, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786783, Length=228, Percent_Identity=25.4385964912281, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=207, Percent_Identity=22.2222222222222, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=118, Percent_Identity=31.3559322033898, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 89468; Mature: 89468

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLKILAQFYVDLMVRLGIVRFSLLLAIALVALAVIVQVGVTLVLSGEVNDLDIIRSVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCHHHHHHHHH
FGLLITPWAVFFLSVVVEHLEDSRQRLSKLVSKLEEMRTRDLDLNKKLKGNVKKLNQEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHH
EREKAEEARQEAMEDLENEVFQREKAQLELAEQTALLRSYLDTSPDIIYYRNDLGLFSGC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHH
NKAMEQLTGKLEKELIGLSPKDVYDAEVAAKVIDTDRQVLQENQALTYEQWLDYPDGRKA
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHH
CFELNKIPFYSKDGRRLGLVGFGRNITERKEYEDALQKASRDKTTFISTISHELRTPLNG
HHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
IVGLSRMLLDSRLDDEQHNYMRTINVSAITLGNIFNDIIDMDKFDRRKLELFPKPLDFIS
HHHHHHHHHHHCCCCHHHHHEEEEEEHHHHHHHHHHHHHCCCHHCCHHHHCCCCHHHHHH
FVTEMENISGLMAEQKGLRFDLERLTDLPPHISVDSTRLRQVLWNLVGNATKFTKEGGVV
HHHHHHHHHHHHHHHCCCEEEHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHEECCCCEE
MSVSADIHQDSAEITFEIEDTGIGIPEEELENVFAMYYQVKQGKDNLHAVGTGIGLAVSK
EEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHH
ELINLMGGDITVTSEVDFGSTFIVTINVPLVDHVEEEEAMPETKSSKSLRIFMLEDIELN
HHHHHCCCCEEEEEECCCCCEEEEEEECCHHHCCCHHHCCCCCCCCCCEEEEEEECCEEC
VTVACSLLESLGHTVDVAMCGEDAIKQFDPTKYDLALLDIQLPDMTGFDVAKILRDKFDN
HHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCC
LPPLIALTANLLKEKDEYFKNGMDEALSKPLSVKALTEVLEQFSMSEKKTDIPSVPQEQE
CCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHH
VSSEPTENDQLIECLLDLEMLESYIEIVGTKPIYANIEMFEKSMKEYIQILDTNMTARDQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCC
DGIVFETHKMKGAAGSIGLKHIQQVAQKAQSPDLPAWWENIDDWVEEIKNEYEHDIQILK
CCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SWLEQQDK
HHHHHCCC
>Mature Secondary Structure
MKQLKILAQFYVDLMVRLGIVRFSLLLAIALVALAVIVQVGVTLVLSGEVNDLDIIRSVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCHHHHHHHHH
FGLLITPWAVFFLSVVVEHLEDSRQRLSKLVSKLEEMRTRDLDLNKKLKGNVKKLNQEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHH
EREKAEEARQEAMEDLENEVFQREKAQLELAEQTALLRSYLDTSPDIIYYRNDLGLFSGC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHH
NKAMEQLTGKLEKELIGLSPKDVYDAEVAAKVIDTDRQVLQENQALTYEQWLDYPDGRKA
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHH
CFELNKIPFYSKDGRRLGLVGFGRNITERKEYEDALQKASRDKTTFISTISHELRTPLNG
HHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
IVGLSRMLLDSRLDDEQHNYMRTINVSAITLGNIFNDIIDMDKFDRRKLELFPKPLDFIS
HHHHHHHHHHHCCCCHHHHHEEEEEEHHHHHHHHHHHHHCCCHHCCHHHHCCCCHHHHHH
FVTEMENISGLMAEQKGLRFDLERLTDLPPHISVDSTRLRQVLWNLVGNATKFTKEGGVV
HHHHHHHHHHHHHHHCCCEEEHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHEECCCCEE
MSVSADIHQDSAEITFEIEDTGIGIPEEELENVFAMYYQVKQGKDNLHAVGTGIGLAVSK
EEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHH
ELINLMGGDITVTSEVDFGSTFIVTINVPLVDHVEEEEAMPETKSSKSLRIFMLEDIELN
HHHHHCCCCEEEEEECCCCCEEEEEEECCHHHCCCHHHCCCCCCCCCCEEEEEEECCEEC
VTVACSLLESLGHTVDVAMCGEDAIKQFDPTKYDLALLDIQLPDMTGFDVAKILRDKFDN
HHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCC
LPPLIALTANLLKEKDEYFKNGMDEALSKPLSVKALTEVLEQFSMSEKKTDIPSVPQEQE
CCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHH
VSSEPTENDQLIECLLDLEMLESYIEIVGTKPIYANIEMFEKSMKEYIQILDTNMTARDQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCC
DGIVFETHKMKGAAGSIGLKHIQQVAQKAQSPDLPAWWENIDDWVEEIKNEYEHDIQILK
CCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SWLEQQDK
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]