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The map label for this gene is udk [H]

Identifier: 59712359

GI number: 59712359

Start: 1978009

End: 1978656

Strand: Reverse

Name: udk [H]

Synonym: VF_1752

Alternate gene names: 59712359

Gene position: 1978656-1978009 (Counterclockwise)

Preceding gene: 59712360

Following gene: 59712358

Centisome position: 68.29

GC content: 38.12

Gene sequence:

>648_bases
ATGTCAGAGAACAGTAATCATCACTGTATTATCGTAGGTATTGCAGGCGCATCAGCTTCAGGTAAAAGCTTGATTGCTTC
AACAATTTATAATGAACTACGAGCAAAAGTTGGCGATCATCAGATTGGTGTAATAACTGAAGACAGTTACTACAAGGACC
AAAGCCACCTGACCATGGAAGAAAGAGTCAAAACAAATTACGATCACCCAAATGCATTGGATCATGAATTGCTTTGTGAA
CATTTAGAGCAACTTATGCGTGGTGAAGCGGTTAATATTCCAACTTACAGTTATACAGAGCATACTCGTACTTCTGAAGT
TGATGTAATGACTCCAAAGAAAGTAATTATTCTTGAAGGTATTTTATTACTAACAGATCCACGTTTACGTAATTTAATGC
ATGCAAGTGTATTTATGGATACTCCTTTAGATATCTGCCTATTACGTCGTGCTCGACGTGATGTAGAAGAGCGTGGCCGT
ACAATGGAATCTGTTTTTGAGCAATACCAAAAAACAGTACGTCCAATGTTCATGCAATTTATTGACCCATCAAAACAGCA
CGCTGACATTATCGTTCCACGTGGTGGTAAAAACCGCATTGCGATTGATGTACTAAAAGCACATATCTCACGCTTATTAA
AAGCGTAA

Upstream 100 bases:

>100_bases
ACACTTAAGTGAAATTTGAGCTGGAAAGTATCACTAGTAATCCCTATAATCAGGCGGTTTTATTAAATATCCGTATATCG
CACACTTTTAGGTATCTTTT

Downstream 100 bases:

>100_bases
GAAATTTATCTTTAAAAGGGCCGACAATTATGTCGGCCTTTTTTTTGTCTCATATCGTATAATTTCGCTATACTCCAATA
TATAACTATCGATAAGCTCA

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MSENSNHHCIIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDSYYKDQSHLTMEERVKTNYDHPNALDHELLCE
HLEQLMRGEAVNIPTYSYTEHTRTSEVDVMTPKKVIILEGILLLTDPRLRNLMHASVFMDTPLDICLLRRARRDVEERGR
TMESVFEQYQKTVRPMFMQFIDPSKQHADIIVPRGGKNRIAIDVLKAHISRLLKA

Sequences:

>Translated_215_residues
MSENSNHHCIIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDSYYKDQSHLTMEERVKTNYDHPNALDHELLCE
HLEQLMRGEAVNIPTYSYTEHTRTSEVDVMTPKKVIILEGILLLTDPRLRNLMHASVFMDTPLDICLLRRARRDVEERGR
TMESVFEQYQKTVRPMFMQFIDPSKQHADIIVPRGGKNRIAIDVLKAHISRLLKA
>Mature_214_residues
SENSNHHCIIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDSYYKDQSHLTMEERVKTNYDHPNALDHELLCEH
LEQLMRGEAVNIPTYSYTEHTRTSEVDVMTPKKVIILEGILLLTDPRLRNLMHASVFMDTPLDICLLRRARRDVEERGRT
MESVFEQYQKTVRPMFMQFIDPSKQHADIIVPRGGKNRIAIDVLKAHISRLLKA

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI18699734, Length=214, Percent_Identity=35.981308411215, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI301129207, Length=200, Percent_Identity=39, Blast_Score=157, Evalue=6e-39,
Organism=Homo sapiens, GI57863312, Length=206, Percent_Identity=37.8640776699029, Blast_Score=157, Evalue=6e-39,
Organism=Homo sapiens, GI13899253, Length=216, Percent_Identity=35.1851851851852, Blast_Score=151, Evalue=5e-37,
Organism=Homo sapiens, GI209863022, Length=153, Percent_Identity=32.0261437908497, Blast_Score=97, Evalue=8e-21,
Organism=Escherichia coli, GI87082034, Length=211, Percent_Identity=71.563981042654, Blast_Score=328, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI17539894, Length=207, Percent_Identity=40.0966183574879, Blast_Score=157, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17539892, Length=210, Percent_Identity=40, Blast_Score=157, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI71981181, Length=214, Percent_Identity=33.1775700934579, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324339, Length=177, Percent_Identity=32.7683615819209, Blast_Score=114, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24649624, Length=217, Percent_Identity=38.7096774193548, Blast_Score=165, Evalue=2e-41,
Organism=Drosophila melanogaster, GI221458995, Length=214, Percent_Identity=38.785046728972, Blast_Score=164, Evalue=4e-41,
Organism=Drosophila melanogaster, GI28573516, Length=202, Percent_Identity=38.6138613861386, Blast_Score=154, Evalue=3e-38,
Organism=Drosophila melanogaster, GI28573514, Length=202, Percent_Identity=38.6138613861386, Blast_Score=154, Evalue=3e-38,
Organism=Drosophila melanogaster, GI28573512, Length=202, Percent_Identity=38.6138613861386, Blast_Score=154, Evalue=3e-38,
Organism=Drosophila melanogaster, GI45550449, Length=202, Percent_Identity=38.6138613861386, Blast_Score=154, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 24522; Mature: 24390

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENSNHHCIIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDSYYKDQSHLTME
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHH
ERVKTNYDHPNALDHELLCEHLEQLMRGEAVNIPTYSYTEHTRTSEVDVMTPKKVIILEG
HHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEHHC
ILLLTDPRLRNLMHASVFMDTPLDICLLRRARRDVEERGRTMESVFEQYQKTVRPMFMQF
HHEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IDPSKQHADIIVPRGGKNRIAIDVLKAHISRLLKA
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SENSNHHCIIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDSYYKDQSHLTME
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHH
ERVKTNYDHPNALDHELLCEHLEQLMRGEAVNIPTYSYTEHTRTSEVDVMTPKKVIILEG
HHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEHHC
ILLLTDPRLRNLMHASVFMDTPLDICLLRRARRDVEERGRTMESVFEQYQKTVRPMFMQF
HHEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IDPSKQHADIIVPRGGKNRIAIDVLKAHISRLLKA
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA