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The map label for this gene is mrp [H]

Identifier: 59712360

GI number: 59712360

Start: 1978761

End: 1979828

Strand: Reverse

Name: mrp [H]

Synonym: VF_1753

Alternate gene names: 59712360

Gene position: 1979828-1978761 (Counterclockwise)

Preceding gene: 59712362

Following gene: 59712359

Centisome position: 68.33

GC content: 39.33

Gene sequence:

>1068_bases
ATGGCATTTCAAACGATGGTAGAGATTAAAAATTGGTTAAATACGTTTACGCATTCGCAACTTTGTGAAGGTTGGGCTGA
TATTTCAAATGTGGTATCGATTGAAGCTACAGGAAATATTAATGTTGTTTTTCCTTTTGTATCAAAGAGCCTACAAACTG
ATTTTAACCACTGGTTAGAAGGACAAAAACTTGAGTTGGCGTTGCCCGATCTCTCTGTATTCGTCTCATCTAAAACCTCG
TCTTTAAAAACAAATCAGCCAGCAGTTAAAGGCGTAAAAAATATCATTGCGGTGAGTTCAGGTAAAGGTGGAGTCGGTAA
ATCAACTACAGCTGTGAATTTAGCATTAGCTCTACACCATTTAGGTGCACGTGTTGGTATATTGGATGCAGATATATACG
GTCCTTCTGTACCTTTGATGCTAGGTGTTGAAGATAAGAAACCAGCGATTGTTGATAATAATAGAATGATGCCAATCGAG
GCTCATGGGCTATACAGTAATTCAATTGGTTACTTAGTCGAAAAAGGCGAAGCGGCAGTGTGGCGTGGCCCTATGGCATC
TAAAGCTTTATCTCAGCTTCTTAATGAAACATGGTGGCCAGATTTGGATTATCTTATTATTGATATGCCACCAGGTACTG
GTGATATTCAACTTACATTGTCTCAACAAGTGCCGACGACAGGAGCTGTAATTGTTACGACACCACAAGATCTAGCATTA
ACTGATGCGATTAAAGGTGTGAATATGTTTACGAAAGTAGATGTGCCTGTGATTGGTGTGGTCGAAAACATGAGTATTCA
TATTTGCTCTAATTGTGGACATCAAGAAGCGATTTTTGGAACTGGTGGCGCATTAACTATGGCTCAACGTTACTCGATCC
CATTATTATCTCAATTACCATTACATATCGATATACGAAGTGAAACGGATTCTGGGACGCCTAGCGTGGCTATTAATTCA
ACAAGTCCTCACAGTAAATTGTATATTAACTTGGCAGAACAAGTATCAAGTCGACTATACTGGCAAGGAGAGGTGATTCC
TGACCAAATAATGTTCAAGTCATTGTAG

Upstream 100 bases:

>100_bases
ATTTAAGAGATAAATAGTACCTGAACCAAGTTAGAAAGCATAGAGGATCAAGGGTTCAATTAGTGATAGGATGAGTAAAA
ATAACCGTGGAGCATTGAAG

Downstream 100 bases:

>100_bases
GATCACACTTAAGTGAAATTTGAGCTGGAAAGTATCACTAGTAATCCCTATAATCAGGCGGTTTTATTAAATATCCGTAT
ATCGCACACTTTTAGGTATC

Product: antiporter inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MAFQTMVEIKNWLNTFTHSQLCEGWADISNVVSIEATGNINVVFPFVSKSLQTDFNHWLEGQKLELALPDLSVFVSSKTS
SLKTNQPAVKGVKNIIAVSSGKGGVGKSTTAVNLALALHHLGARVGILDADIYGPSVPLMLGVEDKKPAIVDNNRMMPIE
AHGLYSNSIGYLVEKGEAAVWRGPMASKALSQLLNETWWPDLDYLIIDMPPGTGDIQLTLSQQVPTTGAVIVTTPQDLAL
TDAIKGVNMFTKVDVPVIGVVENMSIHICSNCGHQEAIFGTGGALTMAQRYSIPLLSQLPLHIDIRSETDSGTPSVAINS
TSPHSKLYINLAEQVSSRLYWQGEVIPDQIMFKSL

Sequences:

>Translated_355_residues
MAFQTMVEIKNWLNTFTHSQLCEGWADISNVVSIEATGNINVVFPFVSKSLQTDFNHWLEGQKLELALPDLSVFVSSKTS
SLKTNQPAVKGVKNIIAVSSGKGGVGKSTTAVNLALALHHLGARVGILDADIYGPSVPLMLGVEDKKPAIVDNNRMMPIE
AHGLYSNSIGYLVEKGEAAVWRGPMASKALSQLLNETWWPDLDYLIIDMPPGTGDIQLTLSQQVPTTGAVIVTTPQDLAL
TDAIKGVNMFTKVDVPVIGVVENMSIHICSNCGHQEAIFGTGGALTMAQRYSIPLLSQLPLHIDIRSETDSGTPSVAINS
TSPHSKLYINLAEQVSSRLYWQGEVIPDQIMFKSL
>Mature_354_residues
AFQTMVEIKNWLNTFTHSQLCEGWADISNVVSIEATGNINVVFPFVSKSLQTDFNHWLEGQKLELALPDLSVFVSSKTSS
LKTNQPAVKGVKNIIAVSSGKGGVGKSTTAVNLALALHHLGARVGILDADIYGPSVPLMLGVEDKKPAIVDNNRMMPIEA
HGLYSNSIGYLVEKGEAAVWRGPMASKALSQLLNETWWPDLDYLIIDMPPGTGDIQLTLSQQVPTTGAVIVTTPQDLALT
DAIKGVNMFTKVDVPVIGVVENMSIHICSNCGHQEAIFGTGGALTMAQRYSIPLLSQLPLHIDIRSETDSGTPSVAINST
SPHSKLYINLAEQVSSRLYWQGEVIPDQIMFKSL

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=257, Percent_Identity=49.4163424124514, Blast_Score=248, Evalue=7e-66,
Organism=Homo sapiens, GI6912540, Length=260, Percent_Identity=36.1538461538462, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI118572611, Length=263, Percent_Identity=38.0228136882129, Blast_Score=163, Evalue=3e-40,
Organism=Escherichia coli, GI87082045, Length=331, Percent_Identity=57.0996978851964, Blast_Score=376, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI25143050, Length=262, Percent_Identity=40.8396946564886, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6322188, Length=227, Percent_Identity=36.1233480176211, Blast_Score=170, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6321347, Length=255, Percent_Identity=36.078431372549, Blast_Score=140, Evalue=3e-34,
Organism=Drosophila melanogaster, GI221511043, Length=261, Percent_Identity=42.5287356321839, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24667611, Length=257, Percent_Identity=38.9105058365759, Blast_Score=171, Evalue=8e-43,
Organism=Drosophila melanogaster, GI19921440, Length=245, Percent_Identity=37.1428571428571, Blast_Score=131, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 38366; Mature: 38234

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFQTMVEIKNWLNTFTHSQLCEGWADISNVVSIEATGNINVVFPFVSKSLQTDFNHWLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEHHHHHHHHHHHHHHCC
GQKLELALPDLSVFVSSKTSSLKTNQPAVKGVKNIIAVSSGKGGVGKSTTAVNLALALHH
CCEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHH
LGARVGILDADIYGPSVPLMLGVEDKKPAIVDNNRMMPIEAHGLYSNSIGYLVEKGEAAV
HCCEEEEEECCCCCCCCCEEEEECCCCCEEECCCEEEEEEECCCCCCCCEEEEECCCEEE
WRGPMASKALSQLLNETWWPDLDYLIIDMPPGTGDIQLTLSQQVPTTGAVIVTTPQDLAL
ECCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCEEEEECCCCHHH
TDAIKGVNMFTKVDVPVIGVVENMSIHICSNCGHQEAIFGTGGALTMAQRYSIPLLSQLP
HHHHCCCCEEEEECCCEEEEEECCEEEEECCCCCCCEEEECCCCEEEHHHCCCCHHHCCC
LHIDIRSETDSGTPSVAINSTSPHSKLYINLAEQVSSRLYWQGEVIPDQIMFKSL
EEEEEECCCCCCCCEEEEECCCCCCEEEEEEHHHHHHCEEECCCCCCHHHHHCCC
>Mature Secondary Structure 
AFQTMVEIKNWLNTFTHSQLCEGWADISNVVSIEATGNINVVFPFVSKSLQTDFNHWLE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEHHHHHHHHHHHHHHCC
GQKLELALPDLSVFVSSKTSSLKTNQPAVKGVKNIIAVSSGKGGVGKSTTAVNLALALHH
CCEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHH
LGARVGILDADIYGPSVPLMLGVEDKKPAIVDNNRMMPIEAHGLYSNSIGYLVEKGEAAV
HCCEEEEEECCCCCCCCCEEEEECCCCCEEECCCEEEEEEECCCCCCCCEEEEECCCEEE
WRGPMASKALSQLLNETWWPDLDYLIIDMPPGTGDIQLTLSQQVPTTGAVIVTTPQDLAL
ECCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCEEEEECCCCHHH
TDAIKGVNMFTKVDVPVIGVVENMSIHICSNCGHQEAIFGTGGALTMAQRYSIPLLSQLP
HHHHCCCCEEEEECCCEEEEEECCEEEEECCCCCCCEEEECCCCEEEHHHCCCCHHHCCC
LHIDIRSETDSGTPSVAINSTSPHSKLYINLAEQVSSRLYWQGEVIPDQIMFKSL
EEEEEECCCCCCCCEEEEECCCCCCEEEEEEHHHHHHCEEECCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]