Click here to switch to the map view.

The map label for this gene is dcuC [H]

Identifier: 59712331

GI number: 59712331

Start: 1943749

End: 1945119

Strand: Direct

Name: dcuC [H]

Synonym: VF_1724

Alternate gene names: 59712331

Gene position: 1943749-1945119 (Clockwise)

Preceding gene: 59712329

Following gene: 59712332

Centisome position: 67.08

GC content: 42.16

Gene sequence:

>1371_bases
ATGTTGGAGTTATTAATTGGTTTAGTAATCACCATATTTGTTGGTTACTTTATCGTAAAAGGATATAAAGCTGCAGGCGT
GTTACTGACAGCAGGTTTAGCACTGCTAATTATTGCAGGTCTTTTAGGTCATTCAGTTCTTCCTGCAAAAGTAACGGCTA
CAGGTAGCCTACTAACAGATGCGCTTGAGTATGTAAAATACATGCTTCAGTACCGTGGCGGCGGCTTAGGTATGCAAATC
ATGCTACTTTGTGGTTTTGCCTCTTACATGACTCACATCGGTGCAAACAATGTGGTTGTTAAGCAATTTTCAAAACCACT
GGCATTCATTAAATCACCTTACATTCTATTAGTTGCCGCTTATATCGTAGCATGTCTAATGTCTCTTGCTGTAAGTTCAG
CTACGGGCCTTGGGGTTCTATTAATGGCAACCCTATTCCCGATGATGACGGCAATGGGTATCTCACGCCCTGCAGCAGTT
GCAGTGTGTGCATCACCAGCAGCAATCATCCTTTCACCTACATCAGGTGACGTCATTGTTGCAGCAGAAAAATCAGGTTT
ACCTCTTCATGTTTTCGCAGTTGAAACCGTACTTCCTGTATCAATTTGTGCAATCATCGTTATGGCAGCAGCCGCGTTCT
TCTGGAATAAATACCTTGATAAGAAAGAAAACACACCAATGGAGAAAGTCGATATTTCTGCAATGGAAGTGAACGCACCA
TCTTACTATGCGATTCTTCCCTTCTTACCTATCGTAGGTGTTTTCCTGTTTAACGGCGAGACAATCCCAGGTCTATCTTT
AGATATTTACACTATCGTTGTTGGTTCTATCTTTATTGGTGCGTTAGTTAACTTTACGACCAATAAACTGAACGGTAAAA
AAACATTAGAAGATTTAGAATCTTGTTATGAAGGTATGGCTGATGCATTTAAAGGCGTAGTTATGCTATTGGTTGCTGCG
GGTGTATTTGCTCAAGGTCTAATGTCTGTTGGCGCAATTGATAACCTACTTCACTTAGCTGATAAAGCAGGTGCGGGTGG
TATGGCTCTAATGCTTCTACTAACCGGTTTAACCGTTGCTGCTGCTATCGCAACAGGTTCTGGTAATGCGCCTTTCTACG
CATTCGTAGAGCTTGCTCCTCAGCTTGCTGGTAAAATGGGTCTTAGCCCTGCATTCCTTATCATTCCAATGCTTCAAGCA
TCTAACCTTGGTCGTACTATTTCACCAGTATCTGGCGTTATCGTTGCGACATCTGGTATGGCAAAAATCAGCCCATTTGA
AGTGGTAAAACGTACATCTGTTCCGGTTATCTGTGGCTTAATCACAGTAATCATCGGTACTATGGTTCTTGTTCCAATGT
ACGCGCAGTAA

Upstream 100 bases:

>100_bases
ACAGATAAAACTTAGGTAAATTTGTGTGATGAAATGTGTAAGAAGATATTTATTAATTACACATTTTTTGAATATTTGAA
ACTTTATAGAGGGAAATTCC

Downstream 100 bases:

>100_bases
TTTTCAAATTTTACGTTTCTTATTAAACGCCAGTTGCTTAATACAACTGGCGTTTTTGTTCCATAGTTACTTAACTTACT
TTCATTTATTCGGCGTTATT

Product: C4-dicarboxylate transporter DcuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MLELLIGLVITIFVGYFIVKGYKAAGVLLTAGLALLIIAGLLGHSVLPAKVTATGSLLTDALEYVKYMLQYRGGGLGMQI
MLLCGFASYMTHIGANNVVVKQFSKPLAFIKSPYILLVAAYIVACLMSLAVSSATGLGVLLMATLFPMMTAMGISRPAAV
AVCASPAAIILSPTSGDVIVAAEKSGLPLHVFAVETVLPVSICAIIVMAAAAFFWNKYLDKKENTPMEKVDISAMEVNAP
SYYAILPFLPIVGVFLFNGETIPGLSLDIYTIVVGSIFIGALVNFTTNKLNGKKTLEDLESCYEGMADAFKGVVMLLVAA
GVFAQGLMSVGAIDNLLHLADKAGAGGMALMLLLTGLTVAAAIATGSGNAPFYAFVELAPQLAGKMGLSPAFLIIPMLQA
SNLGRTISPVSGVIVATSGMAKISPFEVVKRTSVPVICGLITVIIGTMVLVPMYAQ

Sequences:

>Translated_456_residues
MLELLIGLVITIFVGYFIVKGYKAAGVLLTAGLALLIIAGLLGHSVLPAKVTATGSLLTDALEYVKYMLQYRGGGLGMQI
MLLCGFASYMTHIGANNVVVKQFSKPLAFIKSPYILLVAAYIVACLMSLAVSSATGLGVLLMATLFPMMTAMGISRPAAV
AVCASPAAIILSPTSGDVIVAAEKSGLPLHVFAVETVLPVSICAIIVMAAAAFFWNKYLDKKENTPMEKVDISAMEVNAP
SYYAILPFLPIVGVFLFNGETIPGLSLDIYTIVVGSIFIGALVNFTTNKLNGKKTLEDLESCYEGMADAFKGVVMLLVAA
GVFAQGLMSVGAIDNLLHLADKAGAGGMALMLLLTGLTVAAAIATGSGNAPFYAFVELAPQLAGKMGLSPAFLIIPMLQA
SNLGRTISPVSGVIVATSGMAKISPFEVVKRTSVPVICGLITVIIGTMVLVPMYAQ
>Mature_456_residues
MLELLIGLVITIFVGYFIVKGYKAAGVLLTAGLALLIIAGLLGHSVLPAKVTATGSLLTDALEYVKYMLQYRGGGLGMQI
MLLCGFASYMTHIGANNVVVKQFSKPLAFIKSPYILLVAAYIVACLMSLAVSSATGLGVLLMATLFPMMTAMGISRPAAV
AVCASPAAIILSPTSGDVIVAAEKSGLPLHVFAVETVLPVSICAIIVMAAAAFFWNKYLDKKENTPMEKVDISAMEVNAP
SYYAILPFLPIVGVFLFNGETIPGLSLDIYTIVVGSIFIGALVNFTTNKLNGKKTLEDLESCYEGMADAFKGVVMLLVAA
GVFAQGLMSVGAIDNLLHLADKAGAGGMALMLLLTGLTVAAAIATGSGNAPFYAFVELAPQLAGKMGLSPAFLIIPMLQA
SNLGRTISPVSGVIVATSGMAKISPFEVVKRTSVPVICGLITVIIGTMVLVPMYAQ

Specific function: Responsible for the transport of C4-dicarboxylates during anaerobic growth [H]

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1786839, Length=436, Percent_Identity=61.2385321100917, Blast_Score=430, Evalue=1e-122,
Organism=Escherichia coli, GI1789622, Length=454, Percent_Identity=35.9030837004405, Blast_Score=286, Evalue=3e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 47448; Mature: 47448

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELLIGLVITIFVGYFIVKGYKAAGVLLTAGLALLIIAGLLGHSVLPAKVTATGSLLTD
CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
ALEYVKYMLQYRGGGLGMQIMLLCGFASYMTHIGANNVVVKQFSKPLAFIKSPYILLVAA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHH
YIVACLMSLAVSSATGLGVLLMATLFPMMTAMGISRPAAVAVCASPAAIILSPTSGDVIV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCEEEEECCCCCEEE
AAEKSGLPLHVFAVETVLPVSICAIIVMAAAAFFWNKYLDKKENTPMEKVDISAMEVNAP
EECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEECCC
SYYAILPFLPIVGVFLFNGETIPGLSLDIYTIVVGSIFIGALVNFTTNKLNGKKTLEDLE
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SCYEGMADAFKGVVMLLVAAGVFAQGLMSVGAIDNLLHLADKAGAGGMALMLLLTGLTVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AAIATGSGNAPFYAFVELAPQLAGKMGLSPAFLIIPMLQASNLGRTISPVSGVIVATSGM
HHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCC
AKISPFEVVKRTSVPVICGLITVIIGTMVLVPMYAQ
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLELLIGLVITIFVGYFIVKGYKAAGVLLTAGLALLIIAGLLGHSVLPAKVTATGSLLTD
CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
ALEYVKYMLQYRGGGLGMQIMLLCGFASYMTHIGANNVVVKQFSKPLAFIKSPYILLVAA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHH
YIVACLMSLAVSSATGLGVLLMATLFPMMTAMGISRPAAVAVCASPAAIILSPTSGDVIV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCEEEEECCCCCEEE
AAEKSGLPLHVFAVETVLPVSICAIIVMAAAAFFWNKYLDKKENTPMEKVDISAMEVNAP
EECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEECCC
SYYAILPFLPIVGVFLFNGETIPGLSLDIYTIVVGSIFIGALVNFTTNKLNGKKTLEDLE
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SCYEGMADAFKGVVMLLVAAGVFAQGLMSVGAIDNLLHLADKAGAGGMALMLLLTGLTVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AAIATGSGNAPFYAFVELAPQLAGKMGLSPAFLIIPMLQASNLGRTISPVSGVIVATSGM
HHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCC
AKISPFEVVKRTSVPVICGLITVIIGTMVLVPMYAQ
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]