Click here to switch to the map view.

The map label for this gene is yuaR [C]

Identifier: 59712332

GI number: 59712332

Start: 1945318

End: 1946850

Strand: Direct

Name: yuaR [C]

Synonym: VF_1725

Alternate gene names: 59712332

Gene position: 1945318-1946850 (Clockwise)

Preceding gene: 59712331

Following gene: 59712333

Centisome position: 67.14

GC content: 36.2

Gene sequence:

>1533_bases
ATGGCTAGGTTCAAACATCTTTTGGGTTTACTAATAATTTTTAGTCCTTTTTCAAGCTTAGCTGCGGCTACCACTGCTGA
CGAGCAATTATCTTTTGAGTCAACATCTAATGAAGAGAAACCATCAAGAAACGGTATTTATTCTCTTAAAGTTCCCAAAA
ACCACAAAAATCCTGACGGAGAAAAAGTTGATATTTACTATTTTTTTCATAAAGCCACTTCGGAAAGTGATCGCATAGGT
CTTCTGTTTTTTAACTTCGGCGGCCCAGGAGCGGATGCAATAGGAGAGGCAAAATATACGATACAAGATCTCCCTGTGTC
GATAACCAAATCTTTCGATCTGATTTTTTTAGATCCTAGAGGTACAGGTAAAAGTGCGTTCGCAGATAAAATCCGTAAAT
ACGCGAATGAAGTCCGTAAATGTAAAGAAAAGCAAACTTGCGATACCGATGCATTTATCAAAGACATTGCCCTTCCTTAT
GATGCATTTATAAAAGACATTGCCCCTTATATGGGAACGAATGCTGTGGCTGATGATATGGACGCCCTACGCGAGCATCT
CGGTGAAGATAAAATTAGTTACCTCGGTTACTCATACGGAACGAGATTAGGTTCGATTTATGCAGAACGTTATCCTGATC
GGATTCGTGCAGCTGTCCTTGACTCTGCAATGTCACCTATTTTTGAAAATGAAAGGGGACTAAGCATTGATCTGGCAAAA
AACCATGAAAAAATTGCAGAATATCGATTAAATTATAGATTTGAGCGTTTAGAGAAACTAAGAAATATCGTTAGCATTGT
ACGAAATGAATCTAATTATCAGACAAATGATGGTTATAGCTTTGATAAAGAAAAAATATATACACTTTTGTATTTTTTAG
TTGAAAAAGACAATGAAGATTCCATCGATTGGTTTAAGTCGAAGAAGTATGCCGCTATAACTAAGTTACTTGATACAGAT
GAGGGGAAAGATTTTCACGATATATACATTCAAGAGCAAAAAAAACAACAAGAGCAACAAGAGCAATCTACTATGGGCTT
CGTGTATCCTATAGTTTCTTGTACGGATGAAATTACTCCTTTAACAAATGAAGAAATAAGCAATGAGGATAAATACTGGC
AATCATCAATGATATATGGTGGATTTTTATTTGAACTTTTCCAGACCTGTTTAAATTGGAAAGCAGAACGGTCACCGATT
GCTAGTGCTGATGACATTAATAGAAATATTAGTTCCAATATTTTGATAATTGGAGGACGCTATGACCCAAACACAGCTTA
TAACTGGGCAGAAGATATGCATAAAACCATAAAGTCCTCCACTCTTATTACAGTAGATGGATATAACTCAGTACAACATG
GCTTTAGTTTTAGTGGTACCAAATGTGTCGATAAAATAACGACTGAATACCTGTTTAATCCTTCGAAAAAAATTAGCGAT
ACAACCTGTAAAAGATCTCCCCCAAATAATCTGATGTCTTCTCCCAAAAACTGGCGGGAACGTATTGAATATGAGCCTCT
AAGTAAACCATAA

Upstream 100 bases:

>100_bases
TTACAAAATCAGCCAATCATTCACCTGTAAAATCTATCAGTTCCTTCATGTTGATTTATAAATATAAACTGCCCATACAA
CTGACAAATATGGGGCGTCT

Downstream 100 bases:

>100_bases
TCGTAGACATGATAAAAACTGTCAATAAACTGCTTCATGTTGTTCTTACTTATTGACAGTTTTCACTTTATTTGAGTCGA
CCTATAACTTAAAAACAACT

Product: secretory tripeptidyl aminopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MARFKHLLGLLIIFSPFSSLAAATTADEQLSFESTSNEEKPSRNGIYSLKVPKNHKNPDGEKVDIYYFFHKATSESDRIG
LLFFNFGGPGADAIGEAKYTIQDLPVSITKSFDLIFLDPRGTGKSAFADKIRKYANEVRKCKEKQTCDTDAFIKDIALPY
DAFIKDIAPYMGTNAVADDMDALREHLGEDKISYLGYSYGTRLGSIYAERYPDRIRAAVLDSAMSPIFENERGLSIDLAK
NHEKIAEYRLNYRFERLEKLRNIVSIVRNESNYQTNDGYSFDKEKIYTLLYFLVEKDNEDSIDWFKSKKYAAITKLLDTD
EGKDFHDIYIQEQKKQQEQQEQSTMGFVYPIVSCTDEITPLTNEEISNEDKYWQSSMIYGGFLFELFQTCLNWKAERSPI
ASADDINRNISSNILIIGGRYDPNTAYNWAEDMHKTIKSSTLITVDGYNSVQHGFSFSGTKCVDKITTEYLFNPSKKISD
TTCKRSPPNNLMSSPKNWRERIEYEPLSKP

Sequences:

>Translated_510_residues
MARFKHLLGLLIIFSPFSSLAAATTADEQLSFESTSNEEKPSRNGIYSLKVPKNHKNPDGEKVDIYYFFHKATSESDRIG
LLFFNFGGPGADAIGEAKYTIQDLPVSITKSFDLIFLDPRGTGKSAFADKIRKYANEVRKCKEKQTCDTDAFIKDIALPY
DAFIKDIAPYMGTNAVADDMDALREHLGEDKISYLGYSYGTRLGSIYAERYPDRIRAAVLDSAMSPIFENERGLSIDLAK
NHEKIAEYRLNYRFERLEKLRNIVSIVRNESNYQTNDGYSFDKEKIYTLLYFLVEKDNEDSIDWFKSKKYAAITKLLDTD
EGKDFHDIYIQEQKKQQEQQEQSTMGFVYPIVSCTDEITPLTNEEISNEDKYWQSSMIYGGFLFELFQTCLNWKAERSPI
ASADDINRNISSNILIIGGRYDPNTAYNWAEDMHKTIKSSTLITVDGYNSVQHGFSFSGTKCVDKITTEYLFNPSKKISD
TTCKRSPPNNLMSSPKNWRERIEYEPLSKP
>Mature_509_residues
ARFKHLLGLLIIFSPFSSLAAATTADEQLSFESTSNEEKPSRNGIYSLKVPKNHKNPDGEKVDIYYFFHKATSESDRIGL
LFFNFGGPGADAIGEAKYTIQDLPVSITKSFDLIFLDPRGTGKSAFADKIRKYANEVRKCKEKQTCDTDAFIKDIALPYD
AFIKDIAPYMGTNAVADDMDALREHLGEDKISYLGYSYGTRLGSIYAERYPDRIRAAVLDSAMSPIFENERGLSIDLAKN
HEKIAEYRLNYRFERLEKLRNIVSIVRNESNYQTNDGYSFDKEKIYTLLYFLVEKDNEDSIDWFKSKKYAAITKLLDTDE
GKDFHDIYIQEQKKQQEQQEQSTMGFVYPIVSCTDEITPLTNEEISNEDKYWQSSMIYGGFLFELFQTCLNWKAERSPIA
SADDINRNISSNILIIGGRYDPNTAYNWAEDMHKTIKSSTLITVDGYNSVQHGFSFSGTKCVDKITTEYLFNPSKKISDT
TCKRSPPNNLMSSPKNWRERIEYEPLSKP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 58376; Mature: 58245

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARFKHLLGLLIIFSPFSSLAAATTADEQLSFESTSNEEKPSRNGIYSLKVPKNHKNPDG
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
EKVDIYYFFHKATSESDRIGLLFFNFGGPGADAIGEAKYTIQDLPVSITKSFDLIFLDPR
CEEEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCEEHHHCCEEEECCEEEEEECCC
GTGKSAFADKIRKYANEVRKCKEKQTCDTDAFIKDIALPYDAFIKDIAPYMGTNAVADDM
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHH
DALREHLGEDKISYLGYSYGTRLGSIYAERYPDRIRAAVLDSAMSPIFENERGLSIDLAK
HHHHHHHCCCHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEECC
NHEKIAEYRLNYRFERLEKLRNIVSIVRNESNYQTNDGYSFDKEKIYTLLYFLVEKDNED
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
SIDWFKSKKYAAITKLLDTDEGKDFHDIYIQEQKKQQEQQEQSTMGFVYPIVSCTDEITP
CHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
LTNEEISNEDKYWQSSMIYGGFLFELFQTCLNWKAERSPIASADDINRNISSNILIIGGR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCEEEEECC
YDPNTAYNWAEDMHKTIKSSTLITVDGYNSVQHGFSFSGTKCVDKITTEYLFNPSKKISD
CCCCCCHHHHHHHHHHHHCCEEEEECCCCHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCC
TTCKRSPPNNLMSSPKNWRERIEYEPLSKP
CCCCCCCCHHHHCCCHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ARFKHLLGLLIIFSPFSSLAAATTADEQLSFESTSNEEKPSRNGIYSLKVPKNHKNPDG
CHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
EKVDIYYFFHKATSESDRIGLLFFNFGGPGADAIGEAKYTIQDLPVSITKSFDLIFLDPR
CEEEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCEEHHHCCEEEECCEEEEEECCC
GTGKSAFADKIRKYANEVRKCKEKQTCDTDAFIKDIALPYDAFIKDIAPYMGTNAVADDM
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHH
DALREHLGEDKISYLGYSYGTRLGSIYAERYPDRIRAAVLDSAMSPIFENERGLSIDLAK
HHHHHHHCCCHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEECC
NHEKIAEYRLNYRFERLEKLRNIVSIVRNESNYQTNDGYSFDKEKIYTLLYFLVEKDNED
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
SIDWFKSKKYAAITKLLDTDEGKDFHDIYIQEQKKQQEQQEQSTMGFVYPIVSCTDEITP
CHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
LTNEEISNEDKYWQSSMIYGGFLFELFQTCLNWKAERSPIASADDINRNISSNILIIGGR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCEEEEECC
YDPNTAYNWAEDMHKTIKSSTLITVDGYNSVQHGFSFSGTKCVDKITTEYLFNPSKKISD
CCCCCCHHHHHHHHHHHHCCEEEEECCCCHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCC
TTCKRSPPNNLMSSPKNWRERIEYEPLSKP
CCCCCCCCHHHHCCCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]