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The map label for this gene is aapQ [H]

Identifier: 59712140

GI number: 59712140

Start: 1714956

End: 1716122

Strand: Direct

Name: aapQ [H]

Synonym: VF_1533

Alternate gene names: 59712140

Gene position: 1714956-1716122 (Clockwise)

Preceding gene: 59712139

Following gene: 59712141

Centisome position: 59.19

GC content: 38.73

Gene sequence:

>1167_bases
ATGTCATCTAAAAATAAAAACATCTTATATAATCCAACATTTCGTGCGATTTTATTTCAAGTGATAGCAGTTGCTGCACT
TGTCTTTTTTTTCTACACCATAGTTAACAATGCATTATCCAATTTAGAATCTCGTGGTATCGCAACTGGCCTTGGCTTTT
TAGATCAAGAAGCCGGCTTTGGTATCGGCCTTTCTTTAGTGGAGTACGATGAAACATACAGTTATGGTCGCACGTTTGTT
GTCGGATTATTAAACACCGCTCTTGTGTCTGTCCTTGGTATCTTATTTGCTACCGTTTTGGGCTTTACTATTGGTATCGC
ACGACTCTCAAGTAATTGGCTAGTTAGTCGATGTGCCGCAGTTTATATTGAGACTTTCCGAAATATCCCTCTTTTATTAC
AAATTTTCTTTTGGTATTTCGCCGTCTTACAAGCGCTTCCCTCTCCTAGACAAAGTTTGAGTTTAGGTGAAAGTGTCTTT
TTAAACGTTCGTGGTTTATTTTTTCCAAGCCCTATTTTCGAAGAAGGTTCGAACTTAATTGGTATCGCTTTTATTGCCGC
GATTGTATTTATTTTATTTTTATCTAAATGGGCAAAAAACAAACAGCGCATTACAGGGCAGCAAACACCCGTATTACGTT
ACTCTCTTCTTGCTCTGTTTGGTTTACCCACTTTAGCTTATTTTATTTCTGGAATGCCAATATCTATTGAATATCCAGAA
TTAAAAGGATTCAACTTTCGTGGTGGTATTAGCATCATTCCTGAATTAGCGGCATTGGTCGTTGCTCTTAGTGTATATAC
CGCCTCTTTTATTGCTGAGATAGTTCGTTCGGGTATCAATGCCGTGAGCCATGGTCAAACAGAAGCAGCGATGGCACTTG
GTTTACCAAGAAAACGAACCCTTAAATTGGTCGTTATTCCGCAAGCGATGCGAATCATCATTCCCCCTCTCACTAGCCAA
TATTTAAATTTAACTAAAAACTCATCCTTAGCAATGGCAATTGGTTACCCTGACTTAGTTTCGGTGTTTGCAGGAACAAC
ACTAAACCAAACAGGTCAAGCTATTGAGATCATCACAATGACCATGGCGGTGTACCTAACACTAAGCCTATTAACCTCAT
TTTTGATGAACATTTACAACAGCAAAGTTGCATTGGTTGAGAGGTAA

Upstream 100 bases:

>100_bases
CATTCGTTAATCAACTCATAGTCTAATTATAAATATAAAAACACAATTTATGGGGTGAATCTTCACCCCTTTTAATAAAT
GGATTTAAGGTTGTAGTTGT

Downstream 100 bases:

>100_bases
TTATGAATACACATCAATTTCAGCCAGATTTACCACCACCAGCTAATACCGTTGGTGCAGTAACTTGGCTTAAAAAACAT
TTATTTAATGGCCCAATTAA

Product: amino-acid transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSSKNKNILYNPTFRAILFQVIAVAALVFFFYTIVNNALSNLESRGIATGLGFLDQEAGFGIGLSLVEYDETYSYGRTFV
VGLLNTALVSVLGILFATVLGFTIGIARLSSNWLVSRCAAVYIETFRNIPLLLQIFFWYFAVLQALPSPRQSLSLGESVF
LNVRGLFFPSPIFEEGSNLIGIAFIAAIVFILFLSKWAKNKQRITGQQTPVLRYSLLALFGLPTLAYFISGMPISIEYPE
LKGFNFRGGISIIPELAALVVALSVYTASFIAEIVRSGINAVSHGQTEAAMALGLPRKRTLKLVVIPQAMRIIIPPLTSQ
YLNLTKNSSLAMAIGYPDLVSVFAGTTLNQTGQAIEIITMTMAVYLTLSLLTSFLMNIYNSKVALVER

Sequences:

>Translated_388_residues
MSSKNKNILYNPTFRAILFQVIAVAALVFFFYTIVNNALSNLESRGIATGLGFLDQEAGFGIGLSLVEYDETYSYGRTFV
VGLLNTALVSVLGILFATVLGFTIGIARLSSNWLVSRCAAVYIETFRNIPLLLQIFFWYFAVLQALPSPRQSLSLGESVF
LNVRGLFFPSPIFEEGSNLIGIAFIAAIVFILFLSKWAKNKQRITGQQTPVLRYSLLALFGLPTLAYFISGMPISIEYPE
LKGFNFRGGISIIPELAALVVALSVYTASFIAEIVRSGINAVSHGQTEAAMALGLPRKRTLKLVVIPQAMRIIIPPLTSQ
YLNLTKNSSLAMAIGYPDLVSVFAGTTLNQTGQAIEIITMTMAVYLTLSLLTSFLMNIYNSKVALVER
>Mature_387_residues
SSKNKNILYNPTFRAILFQVIAVAALVFFFYTIVNNALSNLESRGIATGLGFLDQEAGFGIGLSLVEYDETYSYGRTFVV
GLLNTALVSVLGILFATVLGFTIGIARLSSNWLVSRCAAVYIETFRNIPLLLQIFFWYFAVLQALPSPRQSLSLGESVFL
NVRGLFFPSPIFEEGSNLIGIAFIAAIVFILFLSKWAKNKQRITGQQTPVLRYSLLALFGLPTLAYFISGMPISIEYPEL
KGFNFRGGISIIPELAALVVALSVYTASFIAEIVRSGINAVSHGQTEAAMALGLPRKRTLKLVVIPQAMRIIIPPLTSQY
LNLTKNSSLAMAIGYPDLVSVFAGTTLNQTGQAIEIITMTMAVYLTLSLLTSFLMNIYNSKVALVER

Specific function: Probably part of the binding-protein-dependent transport system ydhWXYZ for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4597

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994930, Length=382, Percent_Identity=57.5916230366492, Blast_Score=415, Evalue=1e-117,
Organism=Escherichia coli, GI1786874, Length=148, Percent_Identity=32.4324324324324, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786873, Length=130, Percent_Identity=33.0769230769231, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788226, Length=143, Percent_Identity=32.1678321678322, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787030, Length=138, Percent_Identity=30.4347826086957, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082239, Length=97, Percent_Identity=36.0824742268041, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 42484; Mature: 42353

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKNKNILYNPTFRAILFQVIAVAALVFFFYTIVNNALSNLESRGIATGLGFLDQEAGF
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCCCCC
GIGLSLVEYDETYSYGRTFVVGLLNTALVSVLGILFATVLGFTIGIARLSSNWLVSRCAA
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VYIETFRNIPLLLQIFFWYFAVLQALPSPRQSLSLGESVFLNVRGLFFPSPIFEEGSNLI
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHEEEEHHCCCCCCHHHCCCCEE
GIAFIAAIVFILFLSKWAKNKQRITGQQTPVLRYSLLALFGLPTLAYFISGMPISIEYPE
HHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
LKGFNFRGGISIIPELAALVVALSVYTASFIAEIVRSGINAVSHGQTEAAMALGLPRKRT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHCCCCCCC
LKLVVIPQAMRIIIPPLTSQYLNLTKNSSLAMAIGYPDLVSVFAGTTLNQTGQAIEIITM
EEEEEECCHHHHHCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCCCCHHHHHHH
TMAVYLTLSLLTSFLMNIYNSKVALVER
HHHHHHHHHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure 
SSKNKNILYNPTFRAILFQVIAVAALVFFFYTIVNNALSNLESRGIATGLGFLDQEAGF
CCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCCCCC
GIGLSLVEYDETYSYGRTFVVGLLNTALVSVLGILFATVLGFTIGIARLSSNWLVSRCAA
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VYIETFRNIPLLLQIFFWYFAVLQALPSPRQSLSLGESVFLNVRGLFFPSPIFEEGSNLI
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHEEEEHHCCCCCCHHHCCCCEE
GIAFIAAIVFILFLSKWAKNKQRITGQQTPVLRYSLLALFGLPTLAYFISGMPISIEYPE
HHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
LKGFNFRGGISIIPELAALVVALSVYTASFIAEIVRSGINAVSHGQTEAAMALGLPRKRT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHCCCCCCC
LKLVVIPQAMRIIIPPLTSQYLNLTKNSSLAMAIGYPDLVSVFAGTTLNQTGQAIEIITM
EEEEEECCHHHHHCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCCCCHHHHHHH
TMAVYLTLSLLTSFLMNIYNSKVALVER
HHHHHHHHHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]