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The map label for this gene is aapM [H]

Identifier: 59712141

GI number: 59712141

Start: 1716125

End: 1717222

Strand: Direct

Name: aapM [H]

Synonym: VF_1534

Alternate gene names: 59712141

Gene position: 1716125-1717222 (Clockwise)

Preceding gene: 59712140

Following gene: 59712142

Centisome position: 59.23

GC content: 40.89

Gene sequence:

>1098_bases
ATGAATACACATCAATTTCAGCCAGATTTACCACCACCAGCTAATACCGTTGGTGCAGTAACTTGGCTTAAAAAACATTT
ATTTAATGGCCCAATTAACTCCATTCTAACTCTTATTATCGCTTACCTTGCAATCATCGGGTTATGGAATGTGATTTCTT
GGGGCTTAATTAACGCTGATTGGATTGGCACAACCCGTGATGCCTGTTCTAGTGAAGGCGCTTGTTGGGTGATGATAAGC
GTTCGCTGGGACCAATTCATGTATGGTTTTTATCCTAGTGATGAATTGTGGCGTCCACAGCTATTTTATGGGTTATTAGC
GATTTTCGTTGCACTACTAGCTTATGAACACACACCAAAGAAATTTGCGATTTGGTTAATTTTTGTAAATATTTTTCCTA
TCTTCGCAGCCTTTCTTCTTTATGGCGGTGTTTTTGACTTACCGGTTGTAGACACTCACTTATGGGGCGGATTACTAATA
ACTCTCGTAATTGCCATTGTAGGTATTGTCGTTTCTCTTCCTATTGGTGTTGCACTGGCACTTGGTCGACGTTCAGAAAT
GCCTATCATTCGAAGTATGTGTACGGTGTATATCGAAATCTGGCGTGGTGTACCACTCATTACCGTGCTTTTCATGGCTT
CCGTTATGCTTCCGTTGTTTTTATCAGAGGGAATGGAGCTAGATAAACTCTTTAGAGCATTAATTGGTGTTGTTCTATTT
AGTGCCGCTTACATGGCAGAAGTTGTCAGAGGGGGCTTACAAGCGATTCCTAAAGGTCAATACGAGGCTGCAGACGCACT
TGGTTTAGGGTACTGGAAAAAGATGCGCTTAATCATTTTGCCGCAAGCATTGAAAATTACGATCCCTTCTATTGTTAATA
CCTTTATCGGTTTATTCAAAGACACCAGTCTGGTTCTTATTATCGGGATGTTTGATGTGCTAGGTATTGGTCAAGCCGCA
AATACCGACCCTGAATGGCTTGGGTTTTCAACAGAAAGTTATGTCTTCGTCGCTTTGGTTTTCTGGGTGTTCTGTTTCTC
TATGTCGAGATACTCCATCTACTTAGAAAATAAACTTCATACAGGTCATAAGCGATAA

Upstream 100 bases:

>100_bases
TCATCACAATGACCATGGCGGTGTACCTAACACTAAGCCTATTAACCTCATTTTTGATGAACATTTACAACAGCAAAGTT
GCATTGGTTGAGAGGTAATT

Downstream 100 bases:

>100_bases
TTAACAGAATTCAAGGAAGTAGCAATTATGGAAAATCAACAAGATTATATGATCCAACTAGAAGACATGAACAAATGGTA
TGGTCAATTTCATGTTTTAA

Product: amino-acid transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MNTHQFQPDLPPPANTVGAVTWLKKHLFNGPINSILTLIIAYLAIIGLWNVISWGLINADWIGTTRDACSSEGACWVMIS
VRWDQFMYGFYPSDELWRPQLFYGLLAIFVALLAYEHTPKKFAIWLIFVNIFPIFAAFLLYGGVFDLPVVDTHLWGGLLI
TLVIAIVGIVVSLPIGVALALGRRSEMPIIRSMCTVYIEIWRGVPLITVLFMASVMLPLFLSEGMELDKLFRALIGVVLF
SAAYMAEVVRGGLQAIPKGQYEAADALGLGYWKKMRLIILPQALKITIPSIVNTFIGLFKDTSLVLIIGMFDVLGIGQAA
NTDPEWLGFSTESYVFVALVFWVFCFSMSRYSIYLENKLHTGHKR

Sequences:

>Translated_365_residues
MNTHQFQPDLPPPANTVGAVTWLKKHLFNGPINSILTLIIAYLAIIGLWNVISWGLINADWIGTTRDACSSEGACWVMIS
VRWDQFMYGFYPSDELWRPQLFYGLLAIFVALLAYEHTPKKFAIWLIFVNIFPIFAAFLLYGGVFDLPVVDTHLWGGLLI
TLVIAIVGIVVSLPIGVALALGRRSEMPIIRSMCTVYIEIWRGVPLITVLFMASVMLPLFLSEGMELDKLFRALIGVVLF
SAAYMAEVVRGGLQAIPKGQYEAADALGLGYWKKMRLIILPQALKITIPSIVNTFIGLFKDTSLVLIIGMFDVLGIGQAA
NTDPEWLGFSTESYVFVALVFWVFCFSMSRYSIYLENKLHTGHKR
>Mature_365_residues
MNTHQFQPDLPPPANTVGAVTWLKKHLFNGPINSILTLIIAYLAIIGLWNVISWGLINADWIGTTRDACSSEGACWVMIS
VRWDQFMYGFYPSDELWRPQLFYGLLAIFVALLAYEHTPKKFAIWLIFVNIFPIFAAFLLYGGVFDLPVVDTHLWGGLLI
TLVIAIVGIVVSLPIGVALALGRRSEMPIIRSMCTVYIEIWRGVPLITVLFMASVMLPLFLSEGMELDKLFRALIGVVLF
SAAYMAEVVRGGLQAIPKGQYEAADALGLGYWKKMRLIILPQALKITIPSIVNTFIGLFKDTSLVLIIGMFDVLGIGQAA
NTDPEWLGFSTESYVFVALVFWVFCFSMSRYSIYLENKLHTGHKR

Specific function: Probably part of the binding-protein-dependent transport system ydhWXYZ for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082239, Length=364, Percent_Identity=53.5714285714286, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1788226, Length=219, Percent_Identity=37.4429223744292, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786873, Length=211, Percent_Identity=34.1232227488152, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787030, Length=162, Percent_Identity=33.9506172839506, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786874, Length=170, Percent_Identity=28.8235294117647, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788645, Length=178, Percent_Identity=32.0224719101124, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788646, Length=220, Percent_Identity=28.1818181818182, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI48994930, Length=115, Percent_Identity=31.304347826087, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787086, Length=173, Percent_Identity=30.0578034682081, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787087, Length=176, Percent_Identity=27.8409090909091, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 40841; Mature: 40841

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTHQFQPDLPPPANTVGAVTWLKKHLFNGPINSILTLIIAYLAIIGLWNVISWGLINAD
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WIGTTRDACSSEGACWVMISVRWDQFMYGFYPSDELWRPQLFYGLLAIFVALLAYEHTPK
CCCCCHHHHCCCCCEEEEEEEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCH
KFAIWLIFVNIFPIFAAFLLYGGVFDLPVVDTHLWGGLLITLVIAIVGIVVSLPIGVALA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGRRSEMPIIRSMCTVYIEIWRGVPLITVLFMASVMLPLFLSEGMELDKLFRALIGVVLF
HCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SAAYMAEVVRGGLQAIPKGQYEAADALGLGYWKKMRLIILPQALKITIPSIVNTFIGLFK
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEECHHHHEEHHHHHHHHHHHHC
DTSLVLIIGMFDVLGIGQAANTDPEWLGFSTESYVFVALVFWVFCFSMSRYSIYLENKLH
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCC
TGHKR
CCCCC
>Mature Secondary Structure
MNTHQFQPDLPPPANTVGAVTWLKKHLFNGPINSILTLIIAYLAIIGLWNVISWGLINAD
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WIGTTRDACSSEGACWVMISVRWDQFMYGFYPSDELWRPQLFYGLLAIFVALLAYEHTPK
CCCCCHHHHCCCCCEEEEEEEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCH
KFAIWLIFVNIFPIFAAFLLYGGVFDLPVVDTHLWGGLLITLVIAIVGIVVSLPIGVALA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGRRSEMPIIRSMCTVYIEIWRGVPLITVLFMASVMLPLFLSEGMELDKLFRALIGVVLF
HCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SAAYMAEVVRGGLQAIPKGQYEAADALGLGYWKKMRLIILPQALKITIPSIVNTFIGLFK
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEECHHHHEEHHHHHHHHHHHHC
DTSLVLIIGMFDVLGIGQAANTDPEWLGFSTESYVFVALVFWVFCFSMSRYSIYLENKLH
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCC
TGHKR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]