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The map label for this gene is purC [H]

Identifier: 59712105

GI number: 59712105

Start: 1656608

End: 1657711

Strand: Direct

Name: purC [H]

Synonym: VF_1498

Alternate gene names: 59712105

Gene position: 1656608-1657711 (Clockwise)

Preceding gene: 59712100

Following gene: 59712108

Centisome position: 57.17

GC content: 37.14

Gene sequence:

>1104_bases
ATGAGTCTTTCCGATCAAGTGCTTGCAGTTAATGACGATTTACCGATTCGTACTGATAAACCAGTGCATAGTGGTAAAGT
ACGTTCAGTGTATTGGTTAACTGAAGAAGACAGTCGCCGTCTTATTAAAGAAAAGGGATACAATGTTGCACCTGATGCTC
CCCTAGCTATTATGGTGATTAGTGACCGTATTTCTGCATTCGACTGTATCTGGCACGGTGAAGGCGATTTAAAAGGTATT
CCTGGTAAAGGGGCTGCACTAAATGCGATTTCTAACCACTGGTTCCAATTATTTAAAGATAATGGATTAGCAGATAGCCA
TATCCTTGATATTCCACACCCATTTGTATGGATTGTTCAAAAAGCAAAACCAGTAATGATTGAAGCTATTTGCCGTCAAT
ATATTACAGGCTCTATGTGGCGTGCATACACTCAAGGTGAACGCGAATTCTGTGGTATTACTCTACCTGAACGTCTTGAA
AAAGATGAGCAATTGGCTGAACTACTTTTAACACCATCAACAAAAGGCATTTTAAAAGGTATTGATGGGGTTCCTGAAGT
GGATGATGTAAATATCACTCGCAAGAATATCGAGGACAACTACGATAAATTTAATTTCTCTTGTATTGAAGATATCGCTA
CTTACGAGAAATTATTGAAAGAAGGTTTTGCCGTTATTGCTAAAGCATTAAATAAAATAGACCAAATTTTTGTCGATACT
AAATTTGAATTTGGCTATGTAGAAGATGCGCAAGGTAATGAAAAACTGATTTATATGGATGAAGTCGGTACGCCTGATTC
TTCTCGTATTTGGGATACTAAGGCATATCGTTCAGGTCATATTATCGAGAACTCGAAAGAAGGTTTCCGTCAGTTTCTAT
TAAATCACTTCCCTGAACCGGATATTTTATTAAATAAAAACCGCATGGAAGAGCGCTTTGCTTTAGCTGAAGAAAATGCC
CTTCCTTTGGAAGCGATGATGGACCTATCTAAAACCTATTTAGATATCGCAGCAAAAATTACTGGTGCACCAATTACATT
GAGTGATAATCCAAAAGCAGAAATCATCAAAGTATTAAAAGAAGAATATCAATTAGTCGATTAG

Upstream 100 bases:

>100_bases
ACAGAAAAAATAGCAATCGTTTGCTTTTCTTGTGGTAGTCCCAAATAGTTCTGGTATGATGCTCTCAGTTTTTAAACTTT
CTTTATATAGGAATTCTACA

Downstream 100 bases:

>100_bases
TCGATTAGTCGATTAGTCGATTAGTATTTATTTTACTGATGACCAAATAAAAATGGCGACCGCATTGGCCGCCATTTTTT
ATCTCTTCATATAATGAAAA

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSLSDQVLAVNDDLPIRTDKPVHSGKVRSVYWLTEEDSRRLIKEKGYNVAPDAPLAIMVISDRISAFDCIWHGEGDLKGI
PGKGAALNAISNHWFQLFKDNGLADSHILDIPHPFVWIVQKAKPVMIEAICRQYITGSMWRAYTQGEREFCGITLPERLE
KDEQLAELLLTPSTKGILKGIDGVPEVDDVNITRKNIEDNYDKFNFSCIEDIATYEKLLKEGFAVIAKALNKIDQIFVDT
KFEFGYVEDAQGNEKLIYMDEVGTPDSSRIWDTKAYRSGHIIENSKEGFRQFLLNHFPEPDILLNKNRMEERFALAEENA
LPLEAMMDLSKTYLDIAAKITGAPITLSDNPKAEIIKVLKEEYQLVD

Sequences:

>Translated_367_residues
MSLSDQVLAVNDDLPIRTDKPVHSGKVRSVYWLTEEDSRRLIKEKGYNVAPDAPLAIMVISDRISAFDCIWHGEGDLKGI
PGKGAALNAISNHWFQLFKDNGLADSHILDIPHPFVWIVQKAKPVMIEAICRQYITGSMWRAYTQGEREFCGITLPERLE
KDEQLAELLLTPSTKGILKGIDGVPEVDDVNITRKNIEDNYDKFNFSCIEDIATYEKLLKEGFAVIAKALNKIDQIFVDT
KFEFGYVEDAQGNEKLIYMDEVGTPDSSRIWDTKAYRSGHIIENSKEGFRQFLLNHFPEPDILLNKNRMEERFALAEENA
LPLEAMMDLSKTYLDIAAKITGAPITLSDNPKAEIIKVLKEEYQLVD
>Mature_366_residues
SLSDQVLAVNDDLPIRTDKPVHSGKVRSVYWLTEEDSRRLIKEKGYNVAPDAPLAIMVISDRISAFDCIWHGEGDLKGIP
GKGAALNAISNHWFQLFKDNGLADSHILDIPHPFVWIVQKAKPVMIEAICRQYITGSMWRAYTQGEREFCGITLPERLEK
DEQLAELLLTPSTKGILKGIDGVPEVDDVNITRKNIEDNYDKFNFSCIEDIATYEKLLKEGFAVIAKALNKIDQIFVDTK
FEFGYVEDAQGNEKLIYMDEVGTPDSSRIWDTKAYRSGHIIENSKEGFRQFLLNHFPEPDILLNKNRMEERFALAEENAL
PLEAMMDLSKTYLDIAAKITGAPITLSDNPKAEIIKVLKEEYQLVD

Specific function: Unknown

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR014106
- InterPro:   IPR001636 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 41599; Mature: 41468

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSDQVLAVNDDLPIRTDKPVHSGKVRSVYWLTEEDSRRLIKEKGYNVAPDAPLAIMVI
CCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCEEEEEE
SDRISAFDCIWHGEGDLKGIPGKGAALNAISNHWFQLFKDNGLADSHILDIPHPFVWIVQ
ECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEE
KAKPVMIEAICRQYITGSMWRAYTQGEREFCGITLPERLEKDEQLAELLLTPSTKGILKG
CCCHHHHHHHHHHHHCCHHHHHHHCCCCCEECCCCHHHHCHHHHHHHHHHCCCCHHHHHC
IDGVPEVDDVNITRKNIEDNYDKFNFSCIEDIATYEKLLKEGFAVIAKALNKIDQIFVDT
CCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KFEFGYVEDAQGNEKLIYMDEVGTPDSSRIWDTKAYRSGHIIENSKEGFRQFLLNHFPEP
CEECCEEECCCCCCEEEEEECCCCCCCCCEECCHHHCCCCCCCCCHHHHHHHHHHHCCCC
DILLNKNRMEERFALAEENALPLEAMMDLSKTYLDIAAKITGAPITLSDNPKAEIIKVLK
CEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHH
EEYQLVD
HHHHCCC
>Mature Secondary Structure 
SLSDQVLAVNDDLPIRTDKPVHSGKVRSVYWLTEEDSRRLIKEKGYNVAPDAPLAIMVI
CCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCEEEEEE
SDRISAFDCIWHGEGDLKGIPGKGAALNAISNHWFQLFKDNGLADSHILDIPHPFVWIVQ
ECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEE
KAKPVMIEAICRQYITGSMWRAYTQGEREFCGITLPERLEKDEQLAELLLTPSTKGILKG
CCCHHHHHHHHHHHHCCHHHHHHHCCCCCEECCCCHHHHCHHHHHHHHHHCCCCHHHHHC
IDGVPEVDDVNITRKNIEDNYDKFNFSCIEDIATYEKLLKEGFAVIAKALNKIDQIFVDT
CCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KFEFGYVEDAQGNEKLIYMDEVGTPDSSRIWDTKAYRSGHIIENSKEGFRQFLLNHFPEP
CEECCEEECCCCCCEEEEEECCCCCCCCCEECCHHHCCCCCCCCCHHHHHHHHHHHCCCC
DILLNKNRMEERFALAEENALPLEAMMDLSKTYLDIAAKITGAPITLSDNPKAEIIKVLK
CEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHH
EEYQLVD
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA