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The map label for this gene is atoS [H]

Identifier: 59712007

GI number: 59712007

Start: 1548509

End: 1550551

Strand: Reverse

Name: atoS [H]

Synonym: VF_1400

Alternate gene names: 59712007

Gene position: 1550551-1548509 (Counterclockwise)

Preceding gene: 59712008

Following gene: 59712006

Centisome position: 53.51

GC content: 37.54

Gene sequence:

>2043_bases
ATGACGCTATCTCCGACGGTTTGGAAAAAACGCATTAAAACCATGGTGCGTTATCGCTTACTTTGGTTGAACTCGGTTCC
ATTATTCTTAACCTTACTCGCTCTCGTGATCATTACTGCATTTTGGTCTACACATTATACTTGGCAAAATGCACTGAATG
ATGTTGGTAGTAAATTATCTGTTGCCAATAACAGTATTGATTTTTTACAGCGAGAGCAAAGCGCAGAATTGAGAGGCTTT
GTAGAATCGTATTATTTTCAAAAAAAGTTTGAAAATAAAGCACCTGATTTTGAGTTGTGGGTTTCGCAACAAGCGGGGAA
ATACAACTCTGATTTTATTGCGTTACATCCAATCTCTTATATGAATGAGCTACCTTCTTCTTTAGTCAATGATATGAAGA
TTGGTATGTCACGAACCTTCTTTCAAGTCATGTCTGAAAAAGAGTTAGCGGATATTAATCCTAAACTGAAACAACAGGTT
TGGGTGACTAACAAAGAAGATGGAAGTATAGAAAAGCGTGGTTTGATTAGCCGAACGTTAATACCAATTTTTGATAATAA
AGGGACGTTAACTTGGATTGTCGATAGTGGAATTATATTAAATAACAGCACATTACTTGTCGATAGAATCCGTGATTTGA
TCTATCCATCAGGCGATTTACCATCCAATAATATAGGGACAGTAACGTTATTTTTAGATGGACTTCGTATTAGTACCAAC
GTTCCACTGCATACTGATTTTGCAAATAAAGAGCTAAACCAAGGCCGTGCTATTGGAACCAAAGTATCTCCAGAAGTGAA
AGCACAAGTTATTGGTGCTGGAGAGCGATGGGTAAATAGAGCTTATGTTTACAATGATTGGTACATTTCAGCATATCAAC
CGATTAAAGATATGAATGGAGATGTGATTGGAATGCTTTATACCGGCTATTTAGAGTGGCCGCTATTAAAACAGTATTTA
CAAAACTTGCTTGAAGCAGGGATCACCATTCTTATTACGTTATTATTGTCGACCTTTTTTGTGCATCGAGGAGCTCGAGA
TCTATTTCAACCGATCGAAAAAATTCACTTTGTAGTAAAGTCTGTCCAATTAGGTAAAGATGTTCGAATTGGGGACTTAG
GATTAGATAATAGTCATGAACTGGCCAGCTTAGCGCAGCAGTTTGACAATATGCTTGATCAACTTCAGTTACGAAATTTA
GAGATCCAAAGGGCATCTAAAGAGTTAGAGTCAAAAGTTGAATCAAGAACGGCAAGTTTGCATGAAAAGACAGTGGAATT
AGAGCAATACATAAAATTGCTAAAACAAGCTCAAGATAAGCTGGTAATGAGTGAAAAATTGGCATCACTTGGTGAGTTGA
CTGCTGGTATTGCTCATGAAATTAATAATCCTACAGCTGTTATTCTAGGTAATGCAGAATTAATTAAATATGAATTAGGT
GAAGAGGCCCACGTAATAGCTGAAGAGCTAGAAACCATTATGGAGCAAATAGACCGAATCCGTAATATCACTCGTAGTTT
ATTGCAGTACAGTCGACAAGGTGGGATTCAAGATGAGGTGACATGGCAATACATTAATCCAATCATTGAAGAAAGCGTTA
CCTTAGTTCGTACAGGGGCTCACAAACGAGATATTGAGGTTGAGTTTGATTTTGAGCAGCCACCAAGAGTGGAAGTGAAT
CGCCATCATTTATTGCAAGTATTAGTCAATCTGCAAATGAATGGCATCCATGCGATGAACAGTAAAGGTAAACTTATCAT
TCGTAGTCGAACTTGGTGTCATGAAGGGGTTGAGTTTGGTGCGATTATAGAAGTAGAAGATTTTGGATGTGGTATTGCTG
GCGAACAATTGAATCGAATTTTTGACCCGTTCTATACAACAAAGCGTGATGGAACAGGGCTTGGTTTATCTGTTTCTCAA
AGTTTATTAAGTCAAACTGGTGGTGAAATTAAAGTGAGATCACAACTTGGAAAGGGAACCGTCTTTACGATCTATTTGCC
AACAAAGACAGAAGAACAGCAATATCATAATTTGGTAGGTTGA

Upstream 100 bases:

>100_bases
TGGATCTTCATGATGGTAATAAATCTGCAGCTGCAAGGCAGTTGGGGGTTGCTCGTAAAACTTTAGAGCGTAAGTTTAAA
GAGTGGAGCGAAGAAAACGC

Downstream 100 bases:

>100_bases
GTAGCAAGCTAATTAGTGTTACACGACTCACAAAATACGGAACAACTTCAAAATTTGTACTTTTTCTGACCATTGTGTTC
ACAAAAACTGTTGAAATTAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 679

Protein sequence:

>680_residues
MTLSPTVWKKRIKTMVRYRLLWLNSVPLFLTLLALVIITAFWSTHYTWQNALNDVGSKLSVANNSIDFLQREQSAELRGF
VESYYFQKKFENKAPDFELWVSQQAGKYNSDFIALHPISYMNELPSSLVNDMKIGMSRTFFQVMSEKELADINPKLKQQV
WVTNKEDGSIEKRGLISRTLIPIFDNKGTLTWIVDSGIILNNSTLLVDRIRDLIYPSGDLPSNNIGTVTLFLDGLRISTN
VPLHTDFANKELNQGRAIGTKVSPEVKAQVIGAGERWVNRAYVYNDWYISAYQPIKDMNGDVIGMLYTGYLEWPLLKQYL
QNLLEAGITILITLLLSTFFVHRGARDLFQPIEKIHFVVKSVQLGKDVRIGDLGLDNSHELASLAQQFDNMLDQLQLRNL
EIQRASKELESKVESRTASLHEKTVELEQYIKLLKQAQDKLVMSEKLASLGELTAGIAHEINNPTAVILGNAELIKYELG
EEAHVIAEELETIMEQIDRIRNITRSLLQYSRQGGIQDEVTWQYINPIIEESVTLVRTGAHKRDIEVEFDFEQPPRVEVN
RHHLLQVLVNLQMNGIHAMNSKGKLIIRSRTWCHEGVEFGAIIEVEDFGCGIAGEQLNRIFDPFYTTKRDGTGLGLSVSQ
SLLSQTGGEIKVRSQLGKGTVFTIYLPTKTEEQQYHNLVG

Sequences:

>Translated_680_residues
MTLSPTVWKKRIKTMVRYRLLWLNSVPLFLTLLALVIITAFWSTHYTWQNALNDVGSKLSVANNSIDFLQREQSAELRGF
VESYYFQKKFENKAPDFELWVSQQAGKYNSDFIALHPISYMNELPSSLVNDMKIGMSRTFFQVMSEKELADINPKLKQQV
WVTNKEDGSIEKRGLISRTLIPIFDNKGTLTWIVDSGIILNNSTLLVDRIRDLIYPSGDLPSNNIGTVTLFLDGLRISTN
VPLHTDFANKELNQGRAIGTKVSPEVKAQVIGAGERWVNRAYVYNDWYISAYQPIKDMNGDVIGMLYTGYLEWPLLKQYL
QNLLEAGITILITLLLSTFFVHRGARDLFQPIEKIHFVVKSVQLGKDVRIGDLGLDNSHELASLAQQFDNMLDQLQLRNL
EIQRASKELESKVESRTASLHEKTVELEQYIKLLKQAQDKLVMSEKLASLGELTAGIAHEINNPTAVILGNAELIKYELG
EEAHVIAEELETIMEQIDRIRNITRSLLQYSRQGGIQDEVTWQYINPIIEESVTLVRTGAHKRDIEVEFDFEQPPRVEVN
RHHLLQVLVNLQMNGIHAMNSKGKLIIRSRTWCHEGVEFGAIIEVEDFGCGIAGEQLNRIFDPFYTTKRDGTGLGLSVSQ
SLLSQTGGEIKVRSQLGKGTVFTIYLPTKTEEQQYHNLVG
>Mature_679_residues
TLSPTVWKKRIKTMVRYRLLWLNSVPLFLTLLALVIITAFWSTHYTWQNALNDVGSKLSVANNSIDFLQREQSAELRGFV
ESYYFQKKFENKAPDFELWVSQQAGKYNSDFIALHPISYMNELPSSLVNDMKIGMSRTFFQVMSEKELADINPKLKQQVW
VTNKEDGSIEKRGLISRTLIPIFDNKGTLTWIVDSGIILNNSTLLVDRIRDLIYPSGDLPSNNIGTVTLFLDGLRISTNV
PLHTDFANKELNQGRAIGTKVSPEVKAQVIGAGERWVNRAYVYNDWYISAYQPIKDMNGDVIGMLYTGYLEWPLLKQYLQ
NLLEAGITILITLLLSTFFVHRGARDLFQPIEKIHFVVKSVQLGKDVRIGDLGLDNSHELASLAQQFDNMLDQLQLRNLE
IQRASKELESKVESRTASLHEKTVELEQYIKLLKQAQDKLVMSEKLASLGELTAGIAHEINNPTAVILGNAELIKYELGE
EAHVIAEELETIMEQIDRIRNITRSLLQYSRQGGIQDEVTWQYINPIIEESVTLVRTGAHKRDIEVEFDFEQPPRVEVNR
HHLLQVLVNLQMNGIHAMNSKGKLIIRSRTWCHEGVEFGAIIEVEDFGCGIAGEQLNRIFDPFYTTKRDGTGLGLSVSQS
LLSQTGGEIKVRSQLGKGTVFTIYLPTKTEEQQYHNLVG

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=244, Percent_Identity=37.7049180327869, Blast_Score=156, Evalue=4e-39,
Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=36.7768595041322, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1790300, Length=240, Percent_Identity=31.6666666666667, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI87081816, Length=276, Percent_Identity=30.0724637681159, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1789149, Length=460, Percent_Identity=22.1739130434783, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786600, Length=245, Percent_Identity=24.4897959183673, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=128, Percent_Identity=35.9375, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786912, Length=269, Percent_Identity=22.6765799256506, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77262; Mature: 77130

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50109 HIS_KIN ; PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSPTVWKKRIKTMVRYRLLWLNSVPLFLTLLALVIITAFWSTHYTWQNALNDVGSKLS
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEE
VANNSIDFLQREQSAELRGFVESYYFQKKFENKAPDFELWVSQQAGKYNSDFIALHPISY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEECCHHH
MNELPSSLVNDMKIGMSRTFFQVMSEKELADINPKLKQQVWVTNKEDGSIEKRGLISRTL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHEEEEECCCCCCCHHHCCHHHCE
IPIFDNKGTLTWIVDSGIILNNSTLLVDRIRDLIYPSGDLPSNNIGTVTLFLDGLRISTN
EEEECCCCCEEEEEECCEEECCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECEEEECC
VPLHTDFANKELNQGRAIGTKVSPEVKAQVIGAGERWVNRAYVYNDWYISAYQPIKDMNG
CCEECCCCCCHHHCCCCCCCCCCCCHHEEEECCCHHHHCCEEEEECEEEEEECCHHHCCC
DVIGMLYTGYLEWPLLKQYLQNLLEAGITILITLLLSTFFVHRGARDLFQPIEKIHFVVK
CEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SVQLGKDVRIGDLGLDNSHELASLAQQFDNMLDQLQLRNLEIQRASKELESKVESRTASL
HHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
HEKTVELEQYIKLLKQAQDKLVMSEKLASLGELTAGIAHEINNPTAVILGNAELIKYELG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECC
EEAHVIAEELETIMEQIDRIRNITRSLLQYSRQGGIQDEVTWQYINPIIEESVTLVRTGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHEECCC
HKRDIEVEFDFEQPPRVEVNRHHLLQVLVNLQMNGIHAMNSKGKLIIRSRTWCHEGVEFG
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCEEEEECCHHHCCCCCC
AIIEVEDFGCGIAGEQLNRIFDPFYTTKRDGTGLGLSVSQSLLSQTGGEIKVRSQLGKGT
EEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCC
VFTIYLPTKTEEQQYHNLVG
EEEEEECCCCCHHHHHCCCC
>Mature Secondary Structure 
TLSPTVWKKRIKTMVRYRLLWLNSVPLFLTLLALVIITAFWSTHYTWQNALNDVGSKLS
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEE
VANNSIDFLQREQSAELRGFVESYYFQKKFENKAPDFELWVSQQAGKYNSDFIALHPISY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEECCHHH
MNELPSSLVNDMKIGMSRTFFQVMSEKELADINPKLKQQVWVTNKEDGSIEKRGLISRTL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHEEEEECCCCCCCHHHCCHHHCE
IPIFDNKGTLTWIVDSGIILNNSTLLVDRIRDLIYPSGDLPSNNIGTVTLFLDGLRISTN
EEEECCCCCEEEEEECCEEECCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECEEEECC
VPLHTDFANKELNQGRAIGTKVSPEVKAQVIGAGERWVNRAYVYNDWYISAYQPIKDMNG
CCEECCCCCCHHHCCCCCCCCCCCCHHEEEECCCHHHHCCEEEEECEEEEEECCHHHCCC
DVIGMLYTGYLEWPLLKQYLQNLLEAGITILITLLLSTFFVHRGARDLFQPIEKIHFVVK
CEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SVQLGKDVRIGDLGLDNSHELASLAQQFDNMLDQLQLRNLEIQRASKELESKVESRTASL
HHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
HEKTVELEQYIKLLKQAQDKLVMSEKLASLGELTAGIAHEINNPTAVILGNAELIKYELG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECC
EEAHVIAEELETIMEQIDRIRNITRSLLQYSRQGGIQDEVTWQYINPIIEESVTLVRTGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHEECCC
HKRDIEVEFDFEQPPRVEVNRHHLLQVLVNLQMNGIHAMNSKGKLIIRSRTWCHEGVEFG
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCEEEEECCHHHCCCCCC
AIIEVEDFGCGIAGEQLNRIFDPFYTTKRDGTGLGLSVSQSLLSQTGGEIKVRSQLGKGT
EEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCC
VFTIYLPTKTEEQQYHNLVG
EEEEEECCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]