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The map label for this gene is potC [H]

Identifier: 59711924

GI number: 59711924

Start: 1465373

End: 1466143

Strand: Direct

Name: potC [H]

Synonym: VF_1317

Alternate gene names: 59711924

Gene position: 1465373-1466143 (Clockwise)

Preceding gene: 59711923

Following gene: 59711925

Centisome position: 50.57

GC content: 36.84

Gene sequence:

>771_bases
ATGGGACGCACAATTAGATTTAGTTTTATGAGTTTGGTATATCTTTTCTTATACCTACCAATCATCGTTCTGATTGCGAA
CTCATTCAACGCAAGTAAATTTGGTATGAAATGGGGCGGCTTCACTACAAAATGGTATGAAGCGCTAGTAAACAATGACA
GCTTAATGCAAGCAGCTTGGCACTCTATTACTATCGCAGTAATTTCAGGTACCGCTGCAACCATTATTGGTAGTTTAACT
GCAGTTGCCCTTTTCCGTTATCAGTTTAAAGGCAAAAAGTTTGTTAATGGTCTACTGTTTGTTGTGATGATGTCTCCTGA
TATCGTGATGGCAATTTCATTACTGGCTATTTTCCTTGTAATCGGTTTTGAGCTTGGCTTTTTAACACTATTAATCGCTC
ACATCACTTTCTGTTTACCATTCGTGGTAGTAACAGTTTATAGCCGCTTAAAAGGCTTTGATGTGAAAATGTTAGAAGCT
GCACGTGATTTAGGTGCAAGTGAATGGGTAATTCTTAAACAAATTATCCTTCCTCTAGCAAAACCAGCTGTGGCTGCTGG
CTGGTTATTAAGTTTTACCCTTTCATTGGATGATGTAATCATCAGTTCATTTGTAACGGGTCCAACTTACGAAATTTTAC
CATTGAAGATTTACTCAATGGTTAAAGTAGGTATTTCACCTGAAGTGAATGCCTTAGCAACAGTAATGTTGTTTGTTTCT
CTGATTTTAGTTGTACTTTCACAGCTATTAGCAAGAGAAAAAATTAAGTAA

Upstream 100 bases:

>100_bases
GTGCAGCGACCAGTATCGCCCTCACCTTGGCGATGGCATTAATGCTTTATGCTTACTACCGTGCAGGCAAGTTATTAAAC
AAAAAGGCGGATCTAGACTA

Downstream 100 bases:

>100_bases
TAGTTCTATTGTTTTAAATTAATTGTTTCATGCAAACCATCGTTTCATGTAAACAATAAATCTGGAAGACATGCCTTTTG
TTCGACATGTCTTCTTTTTT

Product: spermidine/putrescine ABC transporter membrane protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MGRTIRFSFMSLVYLFLYLPIIVLIANSFNASKFGMKWGGFTTKWYEALVNNDSLMQAAWHSITIAVISGTAATIIGSLT
AVALFRYQFKGKKFVNGLLFVVMMSPDIVMAISLLAIFLVIGFELGFLTLLIAHITFCLPFVVVTVYSRLKGFDVKMLEA
ARDLGASEWVILKQIILPLAKPAVAAGWLLSFTLSLDDVIISSFVTGPTYEILPLKIYSMVKVGISPEVNALATVMLFVS
LILVVLSQLLAREKIK

Sequences:

>Translated_256_residues
MGRTIRFSFMSLVYLFLYLPIIVLIANSFNASKFGMKWGGFTTKWYEALVNNDSLMQAAWHSITIAVISGTAATIIGSLT
AVALFRYQFKGKKFVNGLLFVVMMSPDIVMAISLLAIFLVIGFELGFLTLLIAHITFCLPFVVVTVYSRLKGFDVKMLEA
ARDLGASEWVILKQIILPLAKPAVAAGWLLSFTLSLDDVIISSFVTGPTYEILPLKIYSMVKVGISPEVNALATVMLFVS
LILVVLSQLLAREKIK
>Mature_255_residues
GRTIRFSFMSLVYLFLYLPIIVLIANSFNASKFGMKWGGFTTKWYEALVNNDSLMQAAWHSITIAVISGTAATIIGSLTA
VALFRYQFKGKKFVNGLLFVVMMSPDIVMAISLLAIFLVIGFELGFLTLLIAHITFCLPFVVVTVYSRLKGFDVKMLEAA
RDLGASEWVILKQIILPLAKPAVAAGWLLSFTLSLDDVIISSFVTGPTYEILPLKIYSMVKVGISPEVNALATVMLFVSL
ILVVLSQLLAREKIK

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=256, Percent_Identity=72.65625, Blast_Score=376, Evalue=1e-106,
Organism=Escherichia coli, GI1787081, Length=242, Percent_Identity=42.5619834710744, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI1787714, Length=242, Percent_Identity=30.5785123966942, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1788764, Length=206, Percent_Identity=27.6699029126214, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28232; Mature: 28100

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRTIRFSFMSLVYLFLYLPIIVLIANSFNASKFGMKWGGFTTKWYEALVNNDSLMQAAW
CCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHH
HSITIAVISGTAATIIGSLTAVALFRYQFKGKKFVNGLLFVVMMSPDIVMAISLLAIFLV
HHEEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IGFELGFLTLLIAHITFCLPFVVVTVYSRLKGFDVKMLEAARDLGASEWVILKQIILPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHC
KPAVAAGWLLSFTLSLDDVIISSFVTGPTYEILPLKIYSMVKVGISPEVNALATVMLFVS
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LILVVLSQLLAREKIK
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GRTIRFSFMSLVYLFLYLPIIVLIANSFNASKFGMKWGGFTTKWYEALVNNDSLMQAAW
CCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHH
HSITIAVISGTAATIIGSLTAVALFRYQFKGKKFVNGLLFVVMMSPDIVMAISLLAIFLV
HHEEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IGFELGFLTLLIAHITFCLPFVVVTVYSRLKGFDVKMLEAARDLGASEWVILKQIILPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHC
KPAVAAGWLLSFTLSLDDVIISSFVTGPTYEILPLKIYSMVKVGISPEVNALATVMLFVS
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LILVVLSQLLAREKIK
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]