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The map label for this gene is nudL [H]

Identifier: 59711785

GI number: 59711785

Start: 1308003

End: 1308584

Strand: Reverse

Name: nudL [H]

Synonym: VF_1178

Alternate gene names: 59711785

Gene position: 1308584-1308003 (Counterclockwise)

Preceding gene: 59711786

Following gene: 59711784

Centisome position: 45.16

GC content: 35.22

Gene sequence:

>582_bases
ATGGACACACATTTACTTTCTCATTTGTTACTTCATAAACCGATAAATTACAGTTCAAGTTTACTCTCCCACCCTTTATT
GAAAAATGGCCATTTTAAATCAGCAGCCGTTCTTGTTCCTATTGTAAAAAGAGAAACGGGTTATCACTTAATTTTAACCC
AACGAGCGCCACATTTACGTCATCACCCAAGTCAAATTAGCTTCCCAGGAGGTAAGGTTGAACCCGATGATTTGTCTCTT
ATTCATACAGCTATTCGTGAAACGAATGAAGAGATTGGCATTAATCCTGCACACATTAAACCATTAGTAAAACTTAACAC
AATACCAACAATATCAGGTTATAAAGTAACCCCTATCGTTGCATTAATTGATGAAAATTATACCACCGCAATCGATTACG
GTGAGGTTAGTAGCACATTTGAAGCACCGATAAATCATCTTATTAACCCAAAAAACACCTACAATCATCACGTTTTTAAC
AAAAAACACACATACAATCTGATTTTTATTCCTTTTGATAAAAAACTCATTTGGGGTGTAACTGCCGAAATAATTCACGC
AATGAATTACATAACGGCTTAG

Upstream 100 bases:

>100_bases
GGTGGTATCGTCGCTGATAGTCAAGTTGAACTAGAATATGAAGAGACATTGCATAAGTTAAGCAAAATCTTACCTATTTT
ATAACGATAAGGATCGGTTT

Downstream 100 bases:

>100_bases
AAAATTTATCATTAACGATAAGTTTTTCTAATATTACAGTTACAACTACTGTGATCATTATCAATTATTTTTGGATCTTC
GTTCATCTTTTTTCATTTCT

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MDTHLLSHLLLHKPINYSSSLLSHPLLKNGHFKSAAVLVPIVKRETGYHLILTQRAPHLRHHPSQISFPGGKVEPDDLSL
IHTAIRETNEEIGINPAHIKPLVKLNTIPTISGYKVTPIVALIDENYTTAIDYGEVSSTFEAPINHLINPKNTYNHHVFN
KKHTYNLIFIPFDKKLIWGVTAEIIHAMNYITA

Sequences:

>Translated_193_residues
MDTHLLSHLLLHKPINYSSSLLSHPLLKNGHFKSAAVLVPIVKRETGYHLILTQRAPHLRHHPSQISFPGGKVEPDDLSL
IHTAIRETNEEIGINPAHIKPLVKLNTIPTISGYKVTPIVALIDENYTTAIDYGEVSSTFEAPINHLINPKNTYNHHVFN
KKHTYNLIFIPFDKKLIWGVTAEIIHAMNYITA
>Mature_193_residues
MDTHLLSHLLLHKPINYSSSLLSHPLLKNGHFKSAAVLVPIVKRETGYHLILTQRAPHLRHHPSQISFPGGKVEPDDLSL
IHTAIRETNEEIGINPAHIKPLVKLNTIPTISGYKVTPIVALIDENYTTAIDYGEVSSTFEAPINHLINPKNTYNHHVFN
KKHTYNLIFIPFDKKLIWGVTAEIIHAMNYITA

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=130, Percent_Identity=33.0769230769231, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI1788115, Length=157, Percent_Identity=34.3949044585987, Blast_Score=90, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17536993, Length=133, Percent_Identity=32.3308270676692, Blast_Score=73, Evalue=9e-14,
Organism=Drosophila melanogaster, GI18859683, Length=159, Percent_Identity=30.188679245283, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 21749; Mature: 21749

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTHLLSHLLLHKPINYSSSLLSHPLLKNGHFKSAAVLVPIVKRETGYHLILTQRAPHLR
CCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCEEEEEEEEECCCCCEEEEECCCCCHH
HHPSQISFPGGKVEPDDLSLIHTAIRETNEEIGINPAHIKPLVKLNTIPTISGYKVTPIV
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCHHHCCEEEEECCCCCCCCCEECEEE
ALIDENYTTAIDYGEVSSTFEAPINHLINPKNTYNHHVFNKKHTYNLIFIPFDKKLIWGV
EEEECCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEHHH
TAEIIHAMNYITA
HHHHHHHHHHHCC
>Mature Secondary Structure
MDTHLLSHLLLHKPINYSSSLLSHPLLKNGHFKSAAVLVPIVKRETGYHLILTQRAPHLR
CCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCEEEEEEEEECCCCCEEEEECCCCCHH
HHPSQISFPGGKVEPDDLSLIHTAIRETNEEIGINPAHIKPLVKLNTIPTISGYKVTPIV
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCHHHCCEEEEECCCCCCCCCEECEEE
ALIDENYTTAIDYGEVSSTFEAPINHLINPKNTYNHHVFNKKHTYNLIFIPFDKKLIWGV
EEEECCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEHHH
TAEIIHAMNYITA
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA