Click here to switch to the map view.

The map label for this gene is pabB [H]

Identifier: 59711786

GI number: 59711786

Start: 1308601

End: 1309971

Strand: Reverse

Name: pabB [H]

Synonym: VF_1179

Alternate gene names: 59711786

Gene position: 1309971-1308601 (Counterclockwise)

Preceding gene: 59711793

Following gene: 59711785

Centisome position: 45.21

GC content: 39.24

Gene sequence:

>1371_bases
ATGAACAATCAATTAGATGCAAAACTAAGTATCACTCAACTTGATTATCAATCTAACTCTGTGATTGATTTCTTTTCTGC
TATTGCAAATCAACCTTGGGCGATGTTGCTTAACTCATCAGCACAAAAGCACATTGATAATCGATATGACATTTTGGTTG
CCGATCCTATCGCTACATTACAAACACACGGCGATATCACCACGATTAATGTAATAGGAAAACAACCTGTAACCAGTGAA
GCATGTCCTTTTCAGTTACTTGCGCATTATCAAGAACGCCTAACCCCTTTTTGCAAACCAATACAAGCATTACCTTTCAT
TGGTGGTGCGTTAGGCTATTTCAGCTATGACTTAGGGCGTCGTGTCGAAACGATTCCAAATACGGCACAACATGACATTT
TATGTGCAGATATGGCTGTAGGAATTTATAACTGGGCACTGGTGGCAGATAATAAAACATCAACGTTGTATTTGATACAA
CCCGAAGGTGGTGATCGATTGCATTGGCTTCAACAATTTATTGCTATAAAAGAAGTAGATACACCATTTAGCTTAACCTC
AGACTGGAAATCGAATATGACCGAGTCTGAATACGCTAAAAAGTTCAATACAATTCAGCACTACCTAGAATCAGGGGATT
GTTACCAAATAAACTTAGCACAACGATTTAAAGCACAATATCAGGGCTCTGAATGGGAAGCGTATCAAAAACTAGCCACA
CAAAACGGGGCTCCATTCTCTGCTTATATAAAAACTCCAGAAGTAACGATTCTTTCTGTTTCTCCAGAGCGTTTTTTACA
AGTAAAAGAGCGAAAAATTGAAACAAAACCAATTAAAGGAACCCGACCTCGTTCAAATTATCCTGAGATTGATAAACAAG
AAGCAGAAACGTTGCGTAATAGCCCAAAAGACCGCTCTGAAAACCTGATGATTGTTGATTTGCTGAGAAATGATATAGGC
CGTGTTGCTACACCGGGCTCTGTAAAAGTACCGAAACTGTTTGATATAGAGTCTTTCCCAGCTGTGCATCACTTAGTAAG
TACCATTACAGGTGAACTCAATACAGAATACTCTGCAACAGACTTACTTAAAGCATCTTTCCCTGGTGGTTCTATCACAG
GAGCGCCTAAAATCAGAGCAATGGAGATCATTGAAGAACTCGAACCACATCGCCGTAACTTATATTGTGGCAGTATTGGC
TACATTAGCCGCTGTGGAACAATGGACACCAGTATAACCATACGCACATTAATTGCTTATGAAGGAAGCTTATATGCATC
TGCAGGCGGTGGTATCGTCGCTGATAGTCAAGTTGAACTAGAATATGAAGAGACATTGCATAAGTTAAGCAAAATCTTAC
CTATTTTATAA

Upstream 100 bases:

>100_bases
AATCGCCATCTATTATTTTCTTTTAGAACTCGCATTATGATACTCTTGCTCTCCATCCAAGGCTATCGTTGCTCATCACA
TTCTGGTTATAAAACTCAAA

Downstream 100 bases:

>100_bases
CGATAAGGATCGGTTTATGGACACACATTTACTTTCTCATTTGTTACTTCATAAACCGATAAATTACAGTTCAAGTTTAC
TCTCCCACCCTTTATTGAAA

Product: aminodeoxychorismate synthase, subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MNNQLDAKLSITQLDYQSNSVIDFFSAIANQPWAMLLNSSAQKHIDNRYDILVADPIATLQTHGDITTINVIGKQPVTSE
ACPFQLLAHYQERLTPFCKPIQALPFIGGALGYFSYDLGRRVETIPNTAQHDILCADMAVGIYNWALVADNKTSTLYLIQ
PEGGDRLHWLQQFIAIKEVDTPFSLTSDWKSNMTESEYAKKFNTIQHYLESGDCYQINLAQRFKAQYQGSEWEAYQKLAT
QNGAPFSAYIKTPEVTILSVSPERFLQVKERKIETKPIKGTRPRSNYPEIDKQEAETLRNSPKDRSENLMIVDLLRNDIG
RVATPGSVKVPKLFDIESFPAVHHLVSTITGELNTEYSATDLLKASFPGGSITGAPKIRAMEIIEELEPHRRNLYCGSIG
YISRCGTMDTSITIRTLIAYEGSLYASAGGGIVADSQVELEYEETLHKLSKILPIL

Sequences:

>Translated_456_residues
MNNQLDAKLSITQLDYQSNSVIDFFSAIANQPWAMLLNSSAQKHIDNRYDILVADPIATLQTHGDITTINVIGKQPVTSE
ACPFQLLAHYQERLTPFCKPIQALPFIGGALGYFSYDLGRRVETIPNTAQHDILCADMAVGIYNWALVADNKTSTLYLIQ
PEGGDRLHWLQQFIAIKEVDTPFSLTSDWKSNMTESEYAKKFNTIQHYLESGDCYQINLAQRFKAQYQGSEWEAYQKLAT
QNGAPFSAYIKTPEVTILSVSPERFLQVKERKIETKPIKGTRPRSNYPEIDKQEAETLRNSPKDRSENLMIVDLLRNDIG
RVATPGSVKVPKLFDIESFPAVHHLVSTITGELNTEYSATDLLKASFPGGSITGAPKIRAMEIIEELEPHRRNLYCGSIG
YISRCGTMDTSITIRTLIAYEGSLYASAGGGIVADSQVELEYEETLHKLSKILPIL
>Mature_456_residues
MNNQLDAKLSITQLDYQSNSVIDFFSAIANQPWAMLLNSSAQKHIDNRYDILVADPIATLQTHGDITTINVIGKQPVTSE
ACPFQLLAHYQERLTPFCKPIQALPFIGGALGYFSYDLGRRVETIPNTAQHDILCADMAVGIYNWALVADNKTSTLYLIQ
PEGGDRLHWLQQFIAIKEVDTPFSLTSDWKSNMTESEYAKKFNTIQHYLESGDCYQINLAQRFKAQYQGSEWEAYQKLAT
QNGAPFSAYIKTPEVTILSVSPERFLQVKERKIETKPIKGTRPRSNYPEIDKQEAETLRNSPKDRSENLMIVDLLRNDIG
RVATPGSVKVPKLFDIESFPAVHHLVSTITGELNTEYSATDLLKASFPGGSITGAPKIRAMEIIEELEPHRRNLYCGSIG
YISRCGTMDTSITIRTLIAYEGSLYASAGGGIVADSQVELEYEETLHKLSKILPIL

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=450, Percent_Identity=54, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1787518, Length=498, Percent_Identity=27.3092369477912, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1786809, Length=222, Percent_Identity=26.1261261261261, Blast_Score=82, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6320935, Length=441, Percent_Identity=31.7460317460317, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6324361, Length=400, Percent_Identity=29.5, Blast_Score=159, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 51024; Mature: 51024

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNQLDAKLSITQLDYQSNSVIDFFSAIANQPWAMLLNSSAQKHIDNRYDILVADPIATL
CCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEHHCCCHHHHCCCCCEEEEECCHHHH
QTHGDITTINVIGKQPVTSEACPFQLLAHYQERLTPFCKPIQALPFIGGALGYFSYDLGR
HCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RVETIPNTAQHDILCADMAVGIYNWALVADNKTSTLYLIQPEGGDRLHWLQQFIAIKEVD
HHHHCCCCCCCCEEHHHHHHHHEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCC
TPFSLTSDWKSNMTESEYAKKFNTIQHYLESGDCYQINLAQRFKAQYQGSEWEAYQKLAT
CCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHH
QNGAPFSAYIKTPEVTILSVSPERFLQVKERKIETKPIKGTRPRSNYPEIDKQEAETLRN
CCCCCEEEEEECCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHC
SPKDRSENLMIVDLLRNDIGRVATPGSVKVPKLFDIESFPAVHHLVSTITGELNTEYSAT
CCCCCCCCEEEEEHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCHH
DLLKASFPGGSITGAPKIRAMEIIEELEPHRRNLYCGSIGYISRCGTMDTSITIRTLIAY
HHHEECCCCCCCCCCCCHHHHHHHHHHCCHHCCEEECCCHHHHHCCCCCCCEEEEEEEEE
EGSLYASAGGGIVADSQVELEYEETLHKLSKILPIL
CCCEEEECCCCEEECCEEEEHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNNQLDAKLSITQLDYQSNSVIDFFSAIANQPWAMLLNSSAQKHIDNRYDILVADPIATL
CCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEHHCCCHHHHCCCCCEEEEECCHHHH
QTHGDITTINVIGKQPVTSEACPFQLLAHYQERLTPFCKPIQALPFIGGALGYFSYDLGR
HCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RVETIPNTAQHDILCADMAVGIYNWALVADNKTSTLYLIQPEGGDRLHWLQQFIAIKEVD
HHHHCCCCCCCCEEHHHHHHHHEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCC
TPFSLTSDWKSNMTESEYAKKFNTIQHYLESGDCYQINLAQRFKAQYQGSEWEAYQKLAT
CCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHH
QNGAPFSAYIKTPEVTILSVSPERFLQVKERKIETKPIKGTRPRSNYPEIDKQEAETLRN
CCCCCEEEEEECCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHC
SPKDRSENLMIVDLLRNDIGRVATPGSVKVPKLFDIESFPAVHHLVSTITGELNTEYSAT
CCCCCCCCEEEEEHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCHH
DLLKASFPGGSITGAPKIRAMEIIEELEPHRRNLYCGSIGYISRCGTMDTSITIRTLIAY
HHHEECCCCCCCCCCCCHHHHHHHHHHCCHHCCEEECCCHHHHHCCCCCCCEEEEEEEEE
EGSLYASAGGGIVADSQVELEYEETLHKLSKILPIL
CCCEEEECCCCEEECCEEEEHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]