Click here to switch to the map view.

The map label for this gene is yfeT [H]

Identifier: 59711720

GI number: 59711720

Start: 1225705

End: 1226556

Strand: Reverse

Name: yfeT [H]

Synonym: VF_1113

Alternate gene names: 59711720

Gene position: 1226556-1225705 (Counterclockwise)

Preceding gene: 59711728

Following gene: 59711719

Centisome position: 42.33

GC content: 38.85

Gene sequence:

>852_bases
ATGAATATTTTAGAAAAGATACAGAACCAAAGAAGCAATTTATCCTCAAACGGGATTAAAATTTTGGACTTTATTCTTGA
TGATCCAGCTTCAATCAGCTCCTATTCGAGCCAAGCTCTTGCCGCTAAAGTAGGCGTATCGCAATCAAGTATTGTGAAAC
TTACTCAACGGCTCGGGTTTAAAGGATTTACAGCATTCAAGTTAGCGATTATTGAAGATCTTGGTCGAAAACAAGCGATC
CTCGAACCTGAGCGTCCTATCCATAACAAGATCAATAGTGACGACTCCTCCCTGACCATTGCTCAGAAGTTAGTACAAGA
AAAAACTCACGCACTGATAGCTACAACAAACGCGATTAACTTCTCTGAATTTGAACTCGTCACAACTCTGCTTAACCAAG
CGCAACGTATTCAAATTGTAGGGATTGGTGGCTCCGCATTAACAGCGAAAGATCTGGCCTTCAAATTACTGAAAATTGGA
ATGACAGCACTGACCGAGCAAGATAGTCATGTTCAAATTGCAACGGCAAATACCTTAACCAAACAAGATGTTCAAATCGT
TATCTCATATTCTGGTAGTCGAAAAGAAATCCTAATGGCTGCACAAACAGCAATGGATAAAGGAGCAACGGTGATTGCGT
TAACAAGTACAAAGAAAAGCCCTCTACGTAAGTTGGCTAACTTTTGTATTGATACTATTGCAGATGAAAGACAATTTCGT
AGTTCATCCATTTCATCAAGAACCGCTCAGAATGTCATCACGGATTTACTCTTCATGACGTTGTTACAAATAAAAAGTGA
TAAAGCTAAGCTGTTGATTGATGAAATCTCATCTACTATGAATAGGATCTAA

Upstream 100 bases:

>100_bases
ATGGCACAACTCATTCATATACAACAAGTTACAGAAAGATAAAAACAAAAGAATAATATAAGCAAATTTGGAATAATTAA
TTCAATAAAAATGAGATGGA

Downstream 100 bases:

>100_bases
TATAACTAACAGTCAATATAAGCTGTTATACCACTTATAACCTTTTTTCATGACATTTATTGCTAGACTTTATAAATGTA
TTCAAACGATACAAACATTA

Product: DNA-binding transcriptional regulator

Products: NA

Alternate protein names: MurPQ operon repressor [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MNILEKIQNQRSNLSSNGIKILDFILDDPASISSYSSQALAAKVGVSQSSIVKLTQRLGFKGFTAFKLAIIEDLGRKQAI
LEPERPIHNKINSDDSSLTIAQKLVQEKTHALIATTNAINFSEFELVTTLLNQAQRIQIVGIGGSALTAKDLAFKLLKIG
MTALTEQDSHVQIATANTLTKQDVQIVISYSGSRKEILMAAQTAMDKGATVIALTSTKKSPLRKLANFCIDTIADERQFR
SSSISSRTAQNVITDLLFMTLLQIKSDKAKLLIDEISSTMNRI

Sequences:

>Translated_283_residues
MNILEKIQNQRSNLSSNGIKILDFILDDPASISSYSSQALAAKVGVSQSSIVKLTQRLGFKGFTAFKLAIIEDLGRKQAI
LEPERPIHNKINSDDSSLTIAQKLVQEKTHALIATTNAINFSEFELVTTLLNQAQRIQIVGIGGSALTAKDLAFKLLKIG
MTALTEQDSHVQIATANTLTKQDVQIVISYSGSRKEILMAAQTAMDKGATVIALTSTKKSPLRKLANFCIDTIADERQFR
SSSISSRTAQNVITDLLFMTLLQIKSDKAKLLIDEISSTMNRI
>Mature_283_residues
MNILEKIQNQRSNLSSNGIKILDFILDDPASISSYSSQALAAKVGVSQSSIVKLTQRLGFKGFTAFKLAIIEDLGRKQAI
LEPERPIHNKINSDDSSLTIAQKLVQEKTHALIATTNAINFSEFELVTTLLNQAQRIQIVGIGGSALTAKDLAFKLLKIG
MTALTEQDSHVQIATANTLTKQDVQIVISYSGSRKEILMAAQTAMDKGATVIALTSTKKSPLRKLANFCIDTIADERQFR
SSSISSRTAQNVITDLLFMTLLQIKSDKAKLLIDEISSTMNRI

Specific function: Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of murQ, is the specific inducer tha

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788767, Length=268, Percent_Identity=46.2686567164179, Blast_Score=228, Evalue=2e-61,
Organism=Escherichia coli, GI87082130, Length=263, Percent_Identity=39.9239543726236, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI87082369, Length=263, Percent_Identity=24.3346007604563, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788159, Length=257, Percent_Identity=28.4046692607004, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022821
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30926; Mature: 30926

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILEKIQNQRSNLSSNGIKILDFILDDPASISSYSSQALAAKVGVSQSSIVKLTQRLGF
CCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
KGFTAFKLAIIEDLGRKQAILEPERPIHNKINSDDSSLTIAQKLVQEKTHALIATTNAIN
CCHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHEEEEEECCCC
FSEFELVTTLLNQAQRIQIVGIGGSALTAKDLAFKLLKIGMTALTEQDSHVQIATANTLT
HHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
KQDVQIVISYSGSRKEILMAAQTAMDKGATVIALTSTKKSPLRKLANFCIDTIADERQFR
CCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
SSSISSRTAQNVITDLLFMTLLQIKSDKAKLLIDEISSTMNRI
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNILEKIQNQRSNLSSNGIKILDFILDDPASISSYSSQALAAKVGVSQSSIVKLTQRLGF
CCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
KGFTAFKLAIIEDLGRKQAILEPERPIHNKINSDDSSLTIAQKLVQEKTHALIATTNAIN
CCHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHEEEEEECCCC
FSEFELVTTLLNQAQRIQIVGIGGSALTAKDLAFKLLKIGMTALTEQDSHVQIATANTLT
HHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
KQDVQIVISYSGSRKEILMAAQTAMDKGATVIALTSTKKSPLRKLANFCIDTIADERQFR
CCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
SSSISSRTAQNVITDLLFMTLLQIKSDKAKLLIDEISSTMNRI
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA