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The map label for this gene is tcpI [H]

Identifier: 59711699

GI number: 59711699

Start: 1205130

End: 1207136

Strand: Reverse

Name: tcpI [H]

Synonym: VF_1092

Alternate gene names: 59711699

Gene position: 1207136-1205130 (Counterclockwise)

Preceding gene: 59711704

Following gene: 59711698

Centisome position: 41.66

GC content: 34.13

Gene sequence:

>2007_bases
ATGAATTTCATAAAAAAACTCTCGTTTAAGCAAAAAATCCTTTTAATCATTACCCTTCCGATTATTGGGATGCTCTTCTT
TTCACTTGATACCCTATACAAAACCGTTTCACTACGTTCTGAACTGCAAGACATTACTTCAATGACCGATATTTCAATTG
AAGGCAGTTTAATTGTTCACGAACTTCAAAAAGAACGTGGCTCTACTGCAGGATTTGTTAGTTCAAAAGGGGTAAACTTT
AAAAGTGAAATGCTTGAGCAACGAAAAGAAACCGATTCTGTACTAAATACGTATCTACAATCATTAAAAGAAAAAGCACA
ATCGATACAAAAAACAAATATTGCCGTGTATAACGATATGCAGACAATATTTACGCAATTAAATCAATTAGACACTATTC
GTAATAATGTTGATAATTTGACAATATCAGCATCAAATGCAGCAAAATATTATACGGATATTAACCGACTGTTCTTATCT
TTAAGTAATATGATCGTTAAAACATCAACTGAGCGAACACTAACACCTCATTTGAGAAACTATTCATTATTTTTAGAGAT
CAAAGAATCAGCAGGAAAAGAACGCGCCAGCTTAAATAACATTTTATCAAGTTCTGGTCCTGTCCCTTTAACCTTATACA
AAACATTTGTAGCACTTGATTCAACTCAAAATGCCTACCTTGCTACATTCGTCGAATACGCAACCTCTGAGCAAGTTGAT
GCTTTAAATAAAATACTCTCTGATTCCATTTCACAAAAAGTATCGAACATCCGTGACATGGTAAATGCGCAATATGTTTC
TGGTAAATTTACTGTATCAGGCAGCGAATGGTATCAAGCCTCTACGAATCGAATTAATGAATTTAAACAATACGAAGATT
TACTGGTTGATGATATTGAGAAAGTAATCTCACGTCTAAATAGTGAAGTTAATACGGCTATTTATTCAAGCCTATTCATT
ATCTTGCTTATTTTATCTATTACTATCGTTTCATCAGTCATTATATCTAAACTATTAATTGGCCAAGCTGTACAGCTATC
ACAAGTAATTGAAACGGTATCTAAAGATAAAGATTTAACCATAAGGGCTAAAGTATTATCTGAAGATGAATTAGGTGTGA
GTACTAAATATTTAAATGAAATGCTCGCTGAGTTTCATTCGGTTTTACAAAAAATGGATATTGGTAGCACCCAACTGGCC
ACCAGTGCAGAAGAATCCAATGTAGTAATGGAAGTAACCGCAAATAACTCTCAGCATGAGTTGGCGCAAGTAGAAGAAAT
TTCAACGGCAATCAGTGAGCTATCGAGTACATCTAAAGAAGTAACGACCAATGCGACCCATGCTGAAGAAGAAGCTCAAT
CAGCTATTAATAATGTCGATATTGGTAAACAGCATTTAGAAAATTCGATGTCTTTAACTCGTAGTATTAATGATTCTGTT
CAACAAACAGCATCAATGATTGAAGAATTAAGAGCAAATACAGTTAACATTGGTGAAGTGACTAATGTGATCAGCTCTAT
TTCAGATCAAACTAATCTTCTTGCCCTAAATGCTGCCATTGAAGCAGCAAGAGCCGGCGAACAAGGTCGAGGCTTTGCCG
TCGTTGCTGATGAGGTACGTAACCTAGCAGCTAAAACACAACAATCTACACAACATATTCAAGAAATTATTTCAAAGCTT
CAATATCAATCAGAAAAAGCAAATAATAATATGATTGAAAATGTTACGTTAATTCAACAATCAGTTGTATTAGCTGAAGA
TGTGAAACTGTCTTTCAATGATATAGAAAACTCAGTTCAAGCCATCTCAGATATCAATACATTAGTAGCCACGGCTTCTC
AAGAACAATATTCTGTTACTGAAGATATCGCTAAAAATACAACTCGCACATTTGATTTAGTCAATGAAAATGTATCATCA
ATTCATCAAACACAACTAGTAAGCCAAGAGTTGGCAAAACTCGCTGACCAGCAGAAATCTGAAATCGCTTTATTTAAATT
AAGTTAA

Upstream 100 bases:

>100_bases
GAGAAAGCAAAACGAAATATGAAAAAAACACGTAAAGCTAACACAATGCAATTGACAAATACTAATAACCAAAAAATATT
ATTTACGAAGATTAAGCATC

Downstream 100 bases:

>100_bases
CCTATCATGCCCACTTGTTAACTCAAGTGGGCGATTCAGTTATTACCTTCCATTATAAGTTATGAAAATAATAACGTAAC
TTAACATCATCATTTCATTA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpI [H]

Number of amino acids: Translated: 668; Mature: 668

Protein sequence:

>668_residues
MNFIKKLSFKQKILLIITLPIIGMLFFSLDTLYKTVSLRSELQDITSMTDISIEGSLIVHELQKERGSTAGFVSSKGVNF
KSEMLEQRKETDSVLNTYLQSLKEKAQSIQKTNIAVYNDMQTIFTQLNQLDTIRNNVDNLTISASNAAKYYTDINRLFLS
LSNMIVKTSTERTLTPHLRNYSLFLEIKESAGKERASLNNILSSSGPVPLTLYKTFVALDSTQNAYLATFVEYATSEQVD
ALNKILSDSISQKVSNIRDMVNAQYVSGKFTVSGSEWYQASTNRINEFKQYEDLLVDDIEKVISRLNSEVNTAIYSSLFI
ILLILSITIVSSVIISKLLIGQAVQLSQVIETVSKDKDLTIRAKVLSEDELGVSTKYLNEMLAEFHSVLQKMDIGSTQLA
TSAEESNVVMEVTANNSQHELAQVEEISTAISELSSTSKEVTTNATHAEEEAQSAINNVDIGKQHLENSMSLTRSINDSV
QQTASMIEELRANTVNIGEVTNVISSISDQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAAKTQQSTQHIQEIISKL
QYQSEKANNNMIENVTLIQQSVVLAEDVKLSFNDIENSVQAISDINTLVATASQEQYSVTEDIAKNTTRTFDLVNENVSS
IHQTQLVSQELAKLADQQKSEIALFKLS

Sequences:

>Translated_668_residues
MNFIKKLSFKQKILLIITLPIIGMLFFSLDTLYKTVSLRSELQDITSMTDISIEGSLIVHELQKERGSTAGFVSSKGVNF
KSEMLEQRKETDSVLNTYLQSLKEKAQSIQKTNIAVYNDMQTIFTQLNQLDTIRNNVDNLTISASNAAKYYTDINRLFLS
LSNMIVKTSTERTLTPHLRNYSLFLEIKESAGKERASLNNILSSSGPVPLTLYKTFVALDSTQNAYLATFVEYATSEQVD
ALNKILSDSISQKVSNIRDMVNAQYVSGKFTVSGSEWYQASTNRINEFKQYEDLLVDDIEKVISRLNSEVNTAIYSSLFI
ILLILSITIVSSVIISKLLIGQAVQLSQVIETVSKDKDLTIRAKVLSEDELGVSTKYLNEMLAEFHSVLQKMDIGSTQLA
TSAEESNVVMEVTANNSQHELAQVEEISTAISELSSTSKEVTTNATHAEEEAQSAINNVDIGKQHLENSMSLTRSINDSV
QQTASMIEELRANTVNIGEVTNVISSISDQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAAKTQQSTQHIQEIISKL
QYQSEKANNNMIENVTLIQQSVVLAEDVKLSFNDIENSVQAISDINTLVATASQEQYSVTEDIAKNTTRTFDLVNENVSS
IHQTQLVSQELAKLADQQKSEIALFKLS
>Mature_668_residues
MNFIKKLSFKQKILLIITLPIIGMLFFSLDTLYKTVSLRSELQDITSMTDISIEGSLIVHELQKERGSTAGFVSSKGVNF
KSEMLEQRKETDSVLNTYLQSLKEKAQSIQKTNIAVYNDMQTIFTQLNQLDTIRNNVDNLTISASNAAKYYTDINRLFLS
LSNMIVKTSTERTLTPHLRNYSLFLEIKESAGKERASLNNILSSSGPVPLTLYKTFVALDSTQNAYLATFVEYATSEQVD
ALNKILSDSISQKVSNIRDMVNAQYVSGKFTVSGSEWYQASTNRINEFKQYEDLLVDDIEKVISRLNSEVNTAIYSSLFI
ILLILSITIVSSVIISKLLIGQAVQLSQVIETVSKDKDLTIRAKVLSEDELGVSTKYLNEMLAEFHSVLQKMDIGSTQLA
TSAEESNVVMEVTANNSQHELAQVEEISTAISELSSTSKEVTTNATHAEEEAQSAINNVDIGKQHLENSMSLTRSINDSV
QQTASMIEELRANTVNIGEVTNVISSISDQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAAKTQQSTQHIQEIISKL
QYQSEKANNNMIENVTLIQQSVVLAEDVKLSFNDIENSVQAISDINTLVATASQEQYSVTEDIAKNTTRTFDLVNENVSS
IHQTQLVSQELAKLADQQKSEIALFKLS

Specific function: May function as an environmental regulator of TCP biogenesis. Negatively regulates the synthesis of the major pilin subunit of TCP (tcpA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=356, Percent_Identity=28.9325842696629, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1787690, Length=362, Percent_Identity=27.9005524861878, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788195, Length=220, Percent_Identity=33.1818181818182, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI2367378, Length=315, Percent_Identity=29.2063492063492, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1789453, Length=205, Percent_Identity=33.1707317073171, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 73998; Mature: 73998

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50885 HAMP ; PS50906 NIT ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFIKKLSFKQKILLIITLPIIGMLFFSLDTLYKTVSLRSELQDITSMTDISIEGSLIVH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ELQKERGSTAGFVSSKGVNFKSEMLEQRKETDSVLNTYLQSLKEKAQSIQKTNIAVYNDM
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHH
QTIFTQLNQLDTIRNNVDNLTISASNAAKYYTDINRLFLSLSNMIVKTSTERTLTPHLRN
HHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YSLFLEIKESAGKERASLNNILSSSGPVPLTLYKTFVALDSTQNAYLATFVEYATSEQVD
EEEEEEEHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ALNKILSDSISQKVSNIRDMVNAQYVSGKFTVSGSEWYQASTNRINEFKQYEDLLVDDIE
HHHHHHHHHHHHHHHHHHHHHHHHEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
KVISRLNSEVNTAIYSSLFIILLILSITIVSSVIISKLLIGQAVQLSQVIETVSKDKDLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
IRAKVLSEDELGVSTKYLNEMLAEFHSVLQKMDIGSTQLATSAEESNVVMEVTANNSQHE
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEEECCCCHHH
LAQVEEISTAISELSSTSKEVTTNATHAEEEAQSAINNVDIGKQHLENSMSLTRSINDSV
HHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
QQTASMIEELRANTVNIGEVTNVISSISDQTNLLALNAAIEAARAGEQGRGFAVVADEVR
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHH
NLAAKTQQSTQHIQEIISKLQYQSEKANNNMIENVTLIQQSVVLAEDVKLSFNDIENSVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AISDINTLVATASQEQYSVTEDIAKNTTRTFDLVNENVSSIHQTQLVSQELAKLADQQKS
HHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EIALFKLS
CEEEEEEC
>Mature Secondary Structure
MNFIKKLSFKQKILLIITLPIIGMLFFSLDTLYKTVSLRSELQDITSMTDISIEGSLIVH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ELQKERGSTAGFVSSKGVNFKSEMLEQRKETDSVLNTYLQSLKEKAQSIQKTNIAVYNDM
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHH
QTIFTQLNQLDTIRNNVDNLTISASNAAKYYTDINRLFLSLSNMIVKTSTERTLTPHLRN
HHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YSLFLEIKESAGKERASLNNILSSSGPVPLTLYKTFVALDSTQNAYLATFVEYATSEQVD
EEEEEEEHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ALNKILSDSISQKVSNIRDMVNAQYVSGKFTVSGSEWYQASTNRINEFKQYEDLLVDDIE
HHHHHHHHHHHHHHHHHHHHHHHHEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
KVISRLNSEVNTAIYSSLFIILLILSITIVSSVIISKLLIGQAVQLSQVIETVSKDKDLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
IRAKVLSEDELGVSTKYLNEMLAEFHSVLQKMDIGSTQLATSAEESNVVMEVTANNSQHE
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEEECCCCHHH
LAQVEEISTAISELSSTSKEVTTNATHAEEEAQSAINNVDIGKQHLENSMSLTRSINDSV
HHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
QQTASMIEELRANTVNIGEVTNVISSISDQTNLLALNAAIEAARAGEQGRGFAVVADEVR
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHH
NLAAKTQQSTQHIQEIISKLQYQSEKANNNMIENVTLIQQSVVLAEDVKLSFNDIENSVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AISDINTLVATASQEQYSVTEDIAKNTTRTFDLVNENVSSIHQTQLVSQELAKLADQQKS
HHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EIALFKLS
CEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8005659 [H]