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The map label for this gene is tcpI [H]

Identifier: 59711698

GI number: 59711698

Start: 1203230

End: 1204804

Strand: Reverse

Name: tcpI [H]

Synonym: VF_1091

Alternate gene names: 59711698

Gene position: 1204804-1203230 (Counterclockwise)

Preceding gene: 59711699

Following gene: 172087689

Centisome position: 41.58

GC content: 37.14

Gene sequence:

>1575_bases
ATGCTTCTACTTACCATTTTAGGAATACAAAAAGTAAATATTATTGATCATACTTTAACTGAAATGACTGACATTAATTC
AGTTAAACAACGCTATGCAATCAATTACCGTGGCAGTGTACATGACCGTGCAATTGCTATTAGAGATATTGCTATCGCAA
GAACCCCACAAGAAATATCACATTTAGAAAAAGAGATTAACCGATTACAAACCTTCTATCGTGATTCAGAAGCACAAATG
AAAAAAATGCGCCAAGATGGTATCGCATTTACCAGTGAAGAACTCAGCATTTTAGCTAATATCGAAAAAATTCAAAAAAC
GACATTACCGTTAATCGACCAAGTTATTCGTGATAAAAAGTCAGGTAAACTCACTACTGATGTTGTTTTAGACTCGATTA
GACCGGCGTTTATTCAATGGCTAGATGACATTAACCAGTTTATTGATTATCAAGAAACCCGAAACCAAATCCTTACACCT
GAAGCAAGAAATGTTGCTGGTGGCTTCCAACAATTAATGCTAATTCTTAGCATGTTTGCTTTAGCTACCTCATTATTTAT
TGGTTTGATTATCGAGCGTAGTTTTAGAGTTTCTTTAGGTGGTGAACCTTGGGAGCTATCTGAGATGATTAAGAAGATCT
CTGAAGGTAATCTATCCCAACGTTTTAATAACGCTTCAAGTGCGGTTGGCATCTACAATTCATTAATTATTCTTAATGAA
AAAGTCGGCGCTGCAATCAGAAATAGCAGTGATATTTCAACTCACGTTGCAACATCATCAGAACAGCTAACTGAGGTGAT
GCAAAACACAGCAAATAATGCTCAACATGAATTAGCCCAAGTTGAAGAGATTTCACACGCAATCAGTGAGCTATCGACAA
CGTCAAAAGAAGTAACATCTAATGCAGTTCACGCTGAAGAAGAAGTGAGTAAAGCGATAGACAGTGTTTCTCAAGGCAAC
CAAACCTTAGATGAATCGATTCATTTAACTCAAAAAATCAATGAATCTGTACAACTAACAGCGAGTATGATTGCTGAGCT
AAAAACCAATGCAATGGACATTGGGGAAGTAACTGCAGTTATCAGTACCATTTCAGACCAAACAAATTTATTAGCACTTA
ATGCTGCAATTGAGGCGGCTCGTGCTGGTGAATATGGTCGAGGCTTTGCCGTGGTTGCTGATGAGGTTCGTAATCTTGCA
TCAAAAACTCAAGAATCCACACAAAGTATTCAAGAAATTATCGCTCAATTGCAAGCTCAATCTGAAAAAGCAAACGACAA
CATGATAAGTAACGTGGAGCTTATTCAAGAGTCTGTGGCTTTATCAGAGAATGTAAAATCCTCTTTCAGCTACATTGAGA
ATTCGGTTCAATCTATATCGAAGATGAACACCTTAGTGGCTAGCACCTCTCAAGAGCAGTTCACACTCACAGAACGAATC
GCATTAAATACAACCAACACCTTTGATCTTGTTAATCAAAATGTAGCTGCGATTAATCAAACTCAACAAGCCGCAAAAGA
ACTATCACAACTGGCTGTTTCACAAAAAGAAGAGCTGGCATTCTTTAAAATTTAA

Upstream 100 bases:

>100_bases
ACAATTTAAACAATAAATAAGAGTATATATTTTGGACAAATTTTCAAAGCTAACTATTCGCGCTCGCTTAATAATAGGAT
TTGGTATTACTTTATTCCTA

Downstream 100 bases:

>100_bases
AAAATTGTACTTAAATAAAAAGCCCTTAGGATCTTATCTCTAAGGGCTTTAATATCTGAAACTAAATTCTGTTTTATGTT
ACTTGAGGTTTTCCTCGCCA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpI [H]

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MLLLTILGIQKVNIIDHTLTEMTDINSVKQRYAINYRGSVHDRAIAIRDIAIARTPQEISHLEKEINRLQTFYRDSEAQM
KKMRQDGIAFTSEELSILANIEKIQKTTLPLIDQVIRDKKSGKLTTDVVLDSIRPAFIQWLDDINQFIDYQETRNQILTP
EARNVAGGFQQLMLILSMFALATSLFIGLIIERSFRVSLGGEPWELSEMIKKISEGNLSQRFNNASSAVGIYNSLIILNE
KVGAAIRNSSDISTHVATSSEQLTEVMQNTANNAQHELAQVEEISHAISELSTTSKEVTSNAVHAEEEVSKAIDSVSQGN
QTLDESIHLTQKINESVQLTASMIAELKTNAMDIGEVTAVISTISDQTNLLALNAAIEAARAGEYGRGFAVVADEVRNLA
SKTQESTQSIQEIIAQLQAQSEKANDNMISNVELIQESVALSENVKSSFSYIENSVQSISKMNTLVASTSQEQFTLTERI
ALNTTNTFDLVNQNVAAINQTQQAAKELSQLAVSQKEELAFFKI

Sequences:

>Translated_524_residues
MLLLTILGIQKVNIIDHTLTEMTDINSVKQRYAINYRGSVHDRAIAIRDIAIARTPQEISHLEKEINRLQTFYRDSEAQM
KKMRQDGIAFTSEELSILANIEKIQKTTLPLIDQVIRDKKSGKLTTDVVLDSIRPAFIQWLDDINQFIDYQETRNQILTP
EARNVAGGFQQLMLILSMFALATSLFIGLIIERSFRVSLGGEPWELSEMIKKISEGNLSQRFNNASSAVGIYNSLIILNE
KVGAAIRNSSDISTHVATSSEQLTEVMQNTANNAQHELAQVEEISHAISELSTTSKEVTSNAVHAEEEVSKAIDSVSQGN
QTLDESIHLTQKINESVQLTASMIAELKTNAMDIGEVTAVISTISDQTNLLALNAAIEAARAGEYGRGFAVVADEVRNLA
SKTQESTQSIQEIIAQLQAQSEKANDNMISNVELIQESVALSENVKSSFSYIENSVQSISKMNTLVASTSQEQFTLTERI
ALNTTNTFDLVNQNVAAINQTQQAAKELSQLAVSQKEELAFFKI
>Mature_524_residues
MLLLTILGIQKVNIIDHTLTEMTDINSVKQRYAINYRGSVHDRAIAIRDIAIARTPQEISHLEKEINRLQTFYRDSEAQM
KKMRQDGIAFTSEELSILANIEKIQKTTLPLIDQVIRDKKSGKLTTDVVLDSIRPAFIQWLDDINQFIDYQETRNQILTP
EARNVAGGFQQLMLILSMFALATSLFIGLIIERSFRVSLGGEPWELSEMIKKISEGNLSQRFNNASSAVGIYNSLIILNE
KVGAAIRNSSDISTHVATSSEQLTEVMQNTANNAQHELAQVEEISHAISELSTTSKEVTSNAVHAEEEVSKAIDSVSQGN
QTLDESIHLTQKINESVQLTASMIAELKTNAMDIGEVTAVISTISDQTNLLALNAAIEAARAGEYGRGFAVVADEVRNLA
SKTQESTQSIQEIIAQLQAQSEKANDNMISNVELIQESVALSENVKSSFSYIENSVQSISKMNTLVASTSQEQFTLTERI
ALNTTNTFDLVNQNVAAINQTQQAAKELSQLAVSQKEELAFFKI

Specific function: May function as an environmental regulator of TCP biogenesis. Negatively regulates the synthesis of the major pilin subunit of TCP (tcpA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=400, Percent_Identity=25.25, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788195, Length=297, Percent_Identity=27.9461279461279, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1788194, Length=250, Percent_Identity=28.8, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI2367378, Length=230, Percent_Identity=29.1304347826087, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1789453, Length=172, Percent_Identity=33.7209302325581, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 57927; Mature: 57927

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLTILGIQKVNIIDHTLTEMTDINSVKQRYAINYRGSVHDRAIAIRDIAIARTPQEIS
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHH
HLEKEINRLQTFYRDSEAQMKKMRQDGIAFTSEELSILANIEKIQKTTLPLIDQVIRDKK
HHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SGKLTTDVVLDSIRPAFIQWLDDINQFIDYQETRNQILTPEARNVAGGFQQLMLILSMFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LATSLFIGLIIERSFRVSLGGEPWELSEMIKKISEGNLSQRFNNASSAVGIYNSLIILNE
HHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHEEEEC
KVGAAIRNSSDISTHVATSSEQLTEVMQNTANNAQHELAQVEEISHAISELSTTSKEVTS
HHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAVHAEEEVSKAIDSVSQGNQTLDESIHLTQKINESVQLTASMIAELKTNAMDIGEVTAV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ISTISDQTNLLALNAAIEAARAGEYGRGFAVVADEVRNLASKTQESTQSIQEIIAQLQAQ
HHHHCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEKANDNMISNVELIQESVALSENVKSSFSYIENSVQSISKMNTLVASTSQEQFTLTERI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ALNTTNTFDLVNQNVAAINQTQQAAKELSQLAVSQKEELAFFKI
EECCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHEECC
>Mature Secondary Structure
MLLLTILGIQKVNIIDHTLTEMTDINSVKQRYAINYRGSVHDRAIAIRDIAIARTPQEIS
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHH
HLEKEINRLQTFYRDSEAQMKKMRQDGIAFTSEELSILANIEKIQKTTLPLIDQVIRDKK
HHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SGKLTTDVVLDSIRPAFIQWLDDINQFIDYQETRNQILTPEARNVAGGFQQLMLILSMFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LATSLFIGLIIERSFRVSLGGEPWELSEMIKKISEGNLSQRFNNASSAVGIYNSLIILNE
HHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHEEEEC
KVGAAIRNSSDISTHVATSSEQLTEVMQNTANNAQHELAQVEEISHAISELSTTSKEVTS
HHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAVHAEEEVSKAIDSVSQGNQTLDESIHLTQKINESVQLTASMIAELKTNAMDIGEVTAV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ISTISDQTNLLALNAAIEAARAGEYGRGFAVVADEVRNLASKTQESTQSIQEIIAQLQAQ
HHHHCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEKANDNMISNVELIQESVALSENVKSSFSYIENSVQSISKMNTLVASTSQEQFTLTERI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ALNTTNTFDLVNQNVAAINQTQQAAKELSQLAVSQKEELAFFKI
EECCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8005659 [H]