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The map label for this gene is qor [H]

Identifier: 59711585

GI number: 59711585

Start: 1073830

End: 1074810

Strand: Reverse

Name: qor [H]

Synonym: VF_0978

Alternate gene names: 59711585

Gene position: 1074810-1073830 (Counterclockwise)

Preceding gene: 59711586

Following gene: 59711573

Centisome position: 37.09

GC content: 36.09

Gene sequence:

>981_bases
ATGAGAGCCATCATTCAACAATTTGGACCTGCATTAGAGTCTGTTCAACTCGAACATTACTCCCCTTCAGAACCACTAAT
TAATGAACTTCAAGTAGAAATGAAGCTCAGTACGATTAATCCCTCAGATCTAATAACAATTTCAGGAGCCTATCGCTCTC
GAATAACATTACCATTTGTACCTGGATTTGAAGGTATAGGAAAGGTAACAAAATGCTCAGATTCAACATCTATATTTTCA
ATTGGTGACAGAGTGCTGCCTATTGGCACTGCTGGCGCATGGCAAAAATACCGAAACACAAAAGAGGAGTGGTGCTTTAC
CATTCCAGAAAATTTGAGCGATGAGCAAGCAGCAACGTCATATATAAATCCGATGACTGCATGGTTAATGCTAACTGAAG
CTCTCAATATTCATTCTGATATGTCTATTATTGTTAATGCTGCCAACTCGGCAATCGGATTAATGCTTATTCGAATGTTA
AATCACTTAGGCATTACACCGATTGCTTTAGTTCGCCGAGACAACACTATAGAAGAATTTGAAAACTGCAGAGTTCACAC
CATCATCAATACATCAAATAATGCTGATTACCAACAGCTACTCGATATAACAAAAAATAATAAAATCGATGCTGTATTAG
ACTTCATTGGTGGAGATGATGCCCTTTTATACACCCACATCATAAAAGAACACGGTCAGTTTATTAATTATGGTTTATTG
TCTAAGCAACCAATTCCTGCTGATTTCTGGATTCAACGCCCTGATATTCAATTTTCATATTTTCATCTTAGGCAGTGGAT
ACATTCAGCTGAAAAGCCGCTGATTCAACACAAATTGAATGAAGTAATGAATCTTGTTCATCAAGGAATTGCAGATACAA
CAATTGATCGTTATTTCTCTTTAAAAGAAATTCATCATGCGATTCAATATATTGAAAAAACCAGAACGGTTAATAAAGGA
AAGGTTCTTATCACTTTTTAA

Upstream 100 bases:

>100_bases
TAAGTATGTTGTGCTTTTTTAATAGATATCACTGGTAAGCTTGGTATTACACGCTCATTATGCTACACATAAAACATTAT
TTACCAATATCTTAAATTCA

Downstream 100 bases:

>100_bases
TAAGAACCTTTAAACAATTGACTACTTAATCATTTTTTCCATTGATAGGTGTGGAATATCGGCTTCAATAAACTCTTCGC
CATAAGGTCGGAAACCTAGT

Product: quinone oxidoreductase, NADPH-dependent

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MRAIIQQFGPALESVQLEHYSPSEPLINELQVEMKLSTINPSDLITISGAYRSRITLPFVPGFEGIGKVTKCSDSTSIFS
IGDRVLPIGTAGAWQKYRNTKEEWCFTIPENLSDEQAATSYINPMTAWLMLTEALNIHSDMSIIVNAANSAIGLMLIRML
NHLGITPIALVRRDNTIEEFENCRVHTIINTSNNADYQQLLDITKNNKIDAVLDFIGGDDALLYTHIIKEHGQFINYGLL
SKQPIPADFWIQRPDIQFSYFHLRQWIHSAEKPLIQHKLNEVMNLVHQGIADTTIDRYFSLKEIHHAIQYIEKTRTVNKG
KVLITF

Sequences:

>Translated_326_residues
MRAIIQQFGPALESVQLEHYSPSEPLINELQVEMKLSTINPSDLITISGAYRSRITLPFVPGFEGIGKVTKCSDSTSIFS
IGDRVLPIGTAGAWQKYRNTKEEWCFTIPENLSDEQAATSYINPMTAWLMLTEALNIHSDMSIIVNAANSAIGLMLIRML
NHLGITPIALVRRDNTIEEFENCRVHTIINTSNNADYQQLLDITKNNKIDAVLDFIGGDDALLYTHIIKEHGQFINYGLL
SKQPIPADFWIQRPDIQFSYFHLRQWIHSAEKPLIQHKLNEVMNLVHQGIADTTIDRYFSLKEIHHAIQYIEKTRTVNKG
KVLITF
>Mature_326_residues
MRAIIQQFGPALESVQLEHYSPSEPLINELQVEMKLSTINPSDLITISGAYRSRITLPFVPGFEGIGKVTKCSDSTSIFS
IGDRVLPIGTAGAWQKYRNTKEEWCFTIPENLSDEQAATSYINPMTAWLMLTEALNIHSDMSIIVNAANSAIGLMLIRML
NHLGITPIALVRRDNTIEEFENCRVHTIINTSNNADYQQLLDITKNNKIDAVLDFIGGDDALLYTHIIKEHGQFINYGLL
SKQPIPADFWIQRPDIQFSYFHLRQWIHSAEKPLIQHKLNEVMNLVHQGIADTTIDRYFSLKEIHHAIQYIEKTRTVNKG
KVLITF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI24308257, Length=339, Percent_Identity=25.0737463126844, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI67078404, Length=289, Percent_Identity=24.5674740484429, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI18379349, Length=316, Percent_Identity=24.0506329113924, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI67078406, Length=283, Percent_Identity=24.7349823321555, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI1790485, Length=331, Percent_Identity=25.9818731117825, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17536829, Length=315, Percent_Identity=28.2539682539683, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17556000, Length=252, Percent_Identity=32.5396825396825, Blast_Score=111, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6319520, Length=268, Percent_Identity=24.6268656716418, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319500, Length=298, Percent_Identity=21.4765100671141, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI45550423, Length=289, Percent_Identity=26.643598615917, Blast_Score=109, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 37036; Mature: 37036

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIIQQFGPALESVQLEHYSPSEPLINELQVEMKLSTINPSDLITISGAYRSRITLPFV
CCHHHHHHCCHHHHEEECCCCCCCHHHHHHEEEEEEEECCCCCEEEEECCCCCEEEEECC
PGFEGIGKVTKCSDSTSIFSIGDRVLPIGTAGAWQKYRNTKEEWCFTIPENLSDEQAATS
CCCCCCCCCEECCCCCCEEECCCEEEECCCCHHHHHHCCCCHHEEEECCCCCCHHHHHHH
YINPMTAWLMLTEALNIHSDMSIIVNAANSAIGLMLIRMLNHLGITPIALVRRDNTIEEF
HHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHH
ENCRVHTIINTSNNADYQQLLDITKNNKIDAVLDFIGGDDALLYTHIIKEHGQFINYGLL
HCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCCCEEECCCC
SKQPIPADFWIQRPDIQFSYFHLRQWIHSAEKPLIQHKLNEVMNLVHQGIADTTIDRYFS
CCCCCCHHHEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LKEIHHAIQYIEKTRTVNKGKVLITF
HHHHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MRAIIQQFGPALESVQLEHYSPSEPLINELQVEMKLSTINPSDLITISGAYRSRITLPFV
CCHHHHHHCCHHHHEEECCCCCCCHHHHHHEEEEEEEECCCCCEEEEECCCCCEEEEECC
PGFEGIGKVTKCSDSTSIFSIGDRVLPIGTAGAWQKYRNTKEEWCFTIPENLSDEQAATS
CCCCCCCCCEECCCCCCEEECCCEEEECCCCHHHHHHCCCCHHEEEECCCCCCHHHHHHH
YINPMTAWLMLTEALNIHSDMSIIVNAANSAIGLMLIRMLNHLGITPIALVRRDNTIEEF
HHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHH
ENCRVHTIINTSNNADYQQLLDITKNNKIDAVLDFIGGDDALLYTHIIKEHGQFINYGLL
HCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCCCEEECCCC
SKQPIPADFWIQRPDIQFSYFHLRQWIHSAEKPLIQHKLNEVMNLVHQGIADTTIDRYFS
CCCCCCHHHEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LKEIHHAIQYIEKTRTVNKGKVLITF
HHHHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]