Click here to switch to the map view.

The map label for this gene is znuA [H]

Identifier: 59711437

GI number: 59711437

Start: 911835

End: 912728

Strand: Direct

Name: znuA [H]

Synonym: VF_0830

Alternate gene names: 59711437

Gene position: 911835-912728 (Clockwise)

Preceding gene: 59711434

Following gene: 59711438

Centisome position: 31.47

GC content: 35.91

Gene sequence:

>894_bases
ATGACGAAAAGAATTCAATTCATATTGCTGTGTATATGTACCTTTTGGGGAGTAAATGCACAAGCAATGAGCGTATTATC
TTCAGTAAAGCCGATTAATCTTATTGTACAGGAATTAACAGCAGGTGTAGCGACATCGTCATATTTAGTTCCAAGTGGCG
CGTCACCTCATGATTACGCATTACGTCCATCAGATATGAAAAAAATCCAGAAAGCCGATACCATTGTTTGGTATGGAAAT
GATCTTGAACCTTTCCTTAGTAAAGTTTTAGAAAATAAAAAGAACATCATTACAGTAAGCCAATTTCCTTCTGTTGAATT
TTATCATTTTGACAAGCACGATGAAGATGAACATGCTCATGAAGGGCATCATCACCACAATACAGACCCTCATTTTTGGT
TAGGTCCAAAAGAAACTTTAGGCGTCGCAAAAGAGATAACCAAGCAACTGATTAAAATTGATCCATTGAATAAAGATCAA
TATCAGTCTAACCTTGCACAGTTTGAAAAAAAGTTAACACAGGTAGTGAAAACGATTTCAACTCAATTAGCCCCAGTGAA
AAGTAAAGGTTACTTTGTTTTTCATGATGCATATGGCTATTTTGAGCGTTATTTTGATATGAATAACTTAGGGCACTTTA
CGGTGAGTCCGGATAGAAAACCGGGTGCAAAAACATTGATAAAAATAAAAAAATCACTGGTTTCTCAGCAAGCAGTATGT
GTTTTTTCTGAACCTCAATTTGAGCCAGCTATCGTAACAACGATAACTCGCGGTACTGATGTTCATAAAGGTGAATTAGA
TCCTTTAGCCATACAGCAAGATGAAGTTCCGGGTGCTTATTTTAATTTCTTATTAACCATCAGTAACGAGCTAGAAAGTT
GTCTAAATCAATGA

Upstream 100 bases:

>100_bases
TAAAGTGGTCATTTTTAAATAAGAGTCGTTTGCAATTAGTAAGTGTTATAATGTAACATTTTAAAAATCCAATCGCTATC
ACATTTTTTAAGAGACAAAA

Downstream 100 bases:

>100_bases
AGTATAAAGAAGTATTAGCAGCTCGAATTAATTCACTATCGAAAAGGCATAAGCTTGTTTTAATGTCTTTGTCTCTTTTT
ACGGTAGTTGTTTTTATTTG

Product: zinc ABC transporter periplasmic substrate-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTKRIQFILLCICTFWGVNAQAMSVLSSVKPINLIVQELTAGVATSSYLVPSGASPHDYALRPSDMKKIQKADTIVWYGN
DLEPFLSKVLENKKNIITVSQFPSVEFYHFDKHDEDEHAHEGHHHHNTDPHFWLGPKETLGVAKEITKQLIKIDPLNKDQ
YQSNLAQFEKKLTQVVKTISTQLAPVKSKGYFVFHDAYGYFERYFDMNNLGHFTVSPDRKPGAKTLIKIKKSLVSQQAVC
VFSEPQFEPAIVTTITRGTDVHKGELDPLAIQQDEVPGAYFNFLLTISNELESCLNQ

Sequences:

>Translated_297_residues
MTKRIQFILLCICTFWGVNAQAMSVLSSVKPINLIVQELTAGVATSSYLVPSGASPHDYALRPSDMKKIQKADTIVWYGN
DLEPFLSKVLENKKNIITVSQFPSVEFYHFDKHDEDEHAHEGHHHHNTDPHFWLGPKETLGVAKEITKQLIKIDPLNKDQ
YQSNLAQFEKKLTQVVKTISTQLAPVKSKGYFVFHDAYGYFERYFDMNNLGHFTVSPDRKPGAKTLIKIKKSLVSQQAVC
VFSEPQFEPAIVTTITRGTDVHKGELDPLAIQQDEVPGAYFNFLLTISNELESCLNQ
>Mature_296_residues
TKRIQFILLCICTFWGVNAQAMSVLSSVKPINLIVQELTAGVATSSYLVPSGASPHDYALRPSDMKKIQKADTIVWYGND
LEPFLSKVLENKKNIITVSQFPSVEFYHFDKHDEDEHAHEGHHHHNTDPHFWLGPKETLGVAKEITKQLIKIDPLNKDQY
QSNLAQFEKKLTQVVKTISTQLAPVKSKGYFVFHDAYGYFERYFDMNNLGHFTVSPDRKPGAKTLIKIKKSLVSQQAVCV
FSEPQFEPAIVTTITRGTDVHKGELDPLAIQQDEVPGAYFNFLLTISNELESCLNQ

Specific function: Involved in the high-affinity zinc uptake transport system [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=297, Percent_Identity=40.0673400673401, Blast_Score=233, Evalue=9e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 33611; Mature: 33479

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRIQFILLCICTFWGVNAQAMSVLSSVKPINLIVQELTAGVATSSYLVPSGASPHDYA
CCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCEECCCCCCCCCCC
LRPSDMKKIQKADTIVWYGNDLEPFLSKVLENKKNIITVSQFPSVEFYHFDKHDEDEHAH
CCCHHHHHHHHHCEEEEECCCHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCHHHH
EGHHHHNTDPHFWLGPKETLGVAKEITKQLIKIDPLNKDQYQSNLAQFEKKLTQVVKTIS
CCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TQLAPVKSKGYFVFHDAYGYFERYFDMNNLGHFTVSPDRKPGAKTLIKIKKSLVSQQAVC
HHHCCCCCCCEEEEECHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCEE
VFSEPQFEPAIVTTITRGTDVHKGELDPLAIQQDEVPGAYFNFLLTISNELESCLNQ
EECCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKRIQFILLCICTFWGVNAQAMSVLSSVKPINLIVQELTAGVATSSYLVPSGASPHDYA
CCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCEECCCCCCCCCCC
LRPSDMKKIQKADTIVWYGNDLEPFLSKVLENKKNIITVSQFPSVEFYHFDKHDEDEHAH
CCCHHHHHHHHHCEEEEECCCHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCHHHH
EGHHHHNTDPHFWLGPKETLGVAKEITKQLIKIDPLNKDQYQSNLAQFEKKLTQVVKTIS
CCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TQLAPVKSKGYFVFHDAYGYFERYFDMNNLGHFTVSPDRKPGAKTLIKIKKSLVSQQAVC
HHHCCCCCCCEEEEECHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCEE
VFSEPQFEPAIVTTITRGTDVHKGELDPLAIQQDEVPGAYFNFLLTISNELESCLNQ
EECCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]