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The map label for this gene is mcp4 [H]

Identifier: 59711434

GI number: 59711434

Start: 908444

End: 910099

Strand: Direct

Name: mcp4 [H]

Synonym: VF_0827

Alternate gene names: 59711434

Gene position: 908444-910099 (Clockwise)

Preceding gene: 59711433

Following gene: 59711437

Centisome position: 31.35

GC content: 35.81

Gene sequence:

>1656_bases
ATGAATAGCATGATGATTAATGGTTATTTTTATTTGAGACCTTTTATGCAATTTAATACAAAATCTAAGTATTTTATTAT
CTATGTAATTTTTTCGGCTGCAATGTTTGGTTCCATTATTATGGGGGCATACAACGTACGATTCACTTTAGAAACCAATA
ACGTAACACGTTTAGAAAACTTGCTAACCAATGCGAAAAACACCATTGCTACATTAGAAGAAAAGGCGGCAACAGGTGAG
TTGTCAGAAATTGAAGCTAAGCGTCTTGCAAGTGAGTTGATGCAAAGTTATGCCTATTCCGATAATGAATATATTTGGAT
GACCGATGAAAAGTTAAACTTTTTAGCAGCGCCATTAGATCCTCAAATTATAGGTAAGCATTTCTCAGATATTGTTAGCA
AAGAAGCTGAAACTCATATTATTAATAACTTAACCGTAGCTGGGCAAGTGATTACTTATTCATGGTTCACGACTCGTGAA
AATGTCACAACAGAAGTGAAGTCCATTGCAGTAAAAACCAAACTGTGGAATTGGTATTTAGGTAGTGGTGTTCAAGAGAA
GAAAGTAAACGATACGTTTAAAGCATTCTTATTCGAAGGGTTAACTATTGGTGTTATTGTTAATCTTTTCATTGGATTAG
TGATGTTTTTTGCGGTTAGAAAATACAACAAAACCTTAGGGAATGAGCCCGATGTCATTCTTAATGTTATTGACCGTATT
TCTCGAGGCGATCTAAGTCACTTACCTGAAAAATCGATTGAAAATGTTGGTATCTATAGCCGCATTCTTGATATGGCATC
AAATATCAAAGAGTTAGTTAATGATATAACGGTATTAACAAAAGAGTTAAGTGATTCGTCTCATCATCTATCTGCTTCTT
CTCAAACAATGAATGTTAATGTGAAAACACAAACAGAACAGTTAGAACAAGCTGCTGTTGCCACAGATCAAATTGTTGTT
AGTGTTAATGAAGTAACGAAAAGCGCTGTCCAAGCGACAGATTCAGCGTTAACCGTAAATAGTACATCAGCAGATTGTAT
TAGCACTATCGGTGATATGAACAATGATATGCAACAACTGGCTGGAAATATTAAAGGTGTAGCTGAAGTTATCGGTAATC
TACAAGTCGAAACCGAAAACATTGGCAGTATTTTAGATGTAATTAGAGGTATTGCCGATCAAACAAACTTACTGGCATTA
AATGCTGCGATTGAAGCTGCACGTGCCGGTGAAAGTGGCCGTGGTTTTGCTGTTGTCGCTGATGAAGTTCGTTTACTTGC
GAGTCGAACTCAAGACAGTACTGCTCAAATATCAGAAATGATTGCAGGCTTACAAGATGAAGCTGTTAAATCAGTTAACT
TAATGCAAAGTAACTCAGACGAAGCGCACACAATTGCTGAAAAGACAGTGGTAGCTCAAAATACAGTGAACTCTATCTTT
GAATCGGTTTCAGTAATACAAACCATGAACAGCCAAATATCAGCGTCAACAGAAGAGCAATTAGTTGCAACAACGAACGT
AAATCAGTTAATCACTGATATTAATATGTTTGCAAAAGATAATTTAACGGATGTGGAGTCAACAGCACAACAAGCTGAAA
AACTTGGTTCCATGGCAGATGATTTAACAAGCATTGTAAATCGATTTAAATTATAA

Upstream 100 bases:

>100_bases
TTACATTTAGAGTGGTGAAAAAGAGTACAGGATTCGGATAACTATTTGATAAGATTCGGCGCTTTTTCTTTCTACGACTT
TTATTTATATTACTCAAAGA

Downstream 100 bases:

>100_bases
AAATAAAAAGAGCAAGACGAAATCGTCTTGCTCTTTTTGTATGGTTTCAATCAGGAGACATCGTTGGTCAAATCTTTATG
TAAACCGGTATATTTTAACC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MNSMMINGYFYLRPFMQFNTKSKYFIIYVIFSAAMFGSIIMGAYNVRFTLETNNVTRLENLLTNAKNTIATLEEKAATGE
LSEIEAKRLASELMQSYAYSDNEYIWMTDEKLNFLAAPLDPQIIGKHFSDIVSKEAETHIINNLTVAGQVITYSWFTTRE
NVTTEVKSIAVKTKLWNWYLGSGVQEKKVNDTFKAFLFEGLTIGVIVNLFIGLVMFFAVRKYNKTLGNEPDVILNVIDRI
SRGDLSHLPEKSIENVGIYSRILDMASNIKELVNDITVLTKELSDSSHHLSASSQTMNVNVKTQTEQLEQAAVATDQIVV
SVNEVTKSAVQATDSALTVNSTSADCISTIGDMNNDMQQLAGNIKGVAEVIGNLQVETENIGSILDVIRGIADQTNLLAL
NAAIEAARAGESGRGFAVVADEVRLLASRTQDSTAQISEMIAGLQDEAVKSVNLMQSNSDEAHTIAEKTVVAQNTVNSIF
ESVSVIQTMNSQISASTEEQLVATTNVNQLITDINMFAKDNLTDVESTAQQAEKLGSMADDLTSIVNRFKL

Sequences:

>Translated_551_residues
MNSMMINGYFYLRPFMQFNTKSKYFIIYVIFSAAMFGSIIMGAYNVRFTLETNNVTRLENLLTNAKNTIATLEEKAATGE
LSEIEAKRLASELMQSYAYSDNEYIWMTDEKLNFLAAPLDPQIIGKHFSDIVSKEAETHIINNLTVAGQVITYSWFTTRE
NVTTEVKSIAVKTKLWNWYLGSGVQEKKVNDTFKAFLFEGLTIGVIVNLFIGLVMFFAVRKYNKTLGNEPDVILNVIDRI
SRGDLSHLPEKSIENVGIYSRILDMASNIKELVNDITVLTKELSDSSHHLSASSQTMNVNVKTQTEQLEQAAVATDQIVV
SVNEVTKSAVQATDSALTVNSTSADCISTIGDMNNDMQQLAGNIKGVAEVIGNLQVETENIGSILDVIRGIADQTNLLAL
NAAIEAARAGESGRGFAVVADEVRLLASRTQDSTAQISEMIAGLQDEAVKSVNLMQSNSDEAHTIAEKTVVAQNTVNSIF
ESVSVIQTMNSQISASTEEQLVATTNVNQLITDINMFAKDNLTDVESTAQQAEKLGSMADDLTSIVNRFKL
>Mature_551_residues
MNSMMINGYFYLRPFMQFNTKSKYFIIYVIFSAAMFGSIIMGAYNVRFTLETNNVTRLENLLTNAKNTIATLEEKAATGE
LSEIEAKRLASELMQSYAYSDNEYIWMTDEKLNFLAAPLDPQIIGKHFSDIVSKEAETHIINNLTVAGQVITYSWFTTRE
NVTTEVKSIAVKTKLWNWYLGSGVQEKKVNDTFKAFLFEGLTIGVIVNLFIGLVMFFAVRKYNKTLGNEPDVILNVIDRI
SRGDLSHLPEKSIENVGIYSRILDMASNIKELVNDITVLTKELSDSSHHLSASSQTMNVNVKTQTEQLEQAAVATDQIVV
SVNEVTKSAVQATDSALTVNSTSADCISTIGDMNNDMQQLAGNIKGVAEVIGNLQVETENIGSILDVIRGIADQTNLLAL
NAAIEAARAGESGRGFAVVADEVRLLASRTQDSTAQISEMIAGLQDEAVKSVNLMQSNSDEAHTIAEKTVVAQNTVNSIF
ESVSVIQTMNSQISASTEEQLVATTNVNQLITDINMFAKDNLTDVESTAQQAEKLGSMADDLTSIVNRFKL

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=317, Percent_Identity=32.1766561514196, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1788194, Length=377, Percent_Identity=28.6472148541114, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1789453, Length=296, Percent_Identity=28.3783783783784, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1788195, Length=304, Percent_Identity=29.9342105263158, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI2367378, Length=329, Percent_Identity=27.9635258358663, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 60530; Mature: 60530

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSMMINGYFYLRPFMQFNTKSKYFIIYVIFSAAMFGSIIMGAYNVRFTLETNNVTRLEN
CCCEEEECEEEEEHHHHCCCCCCEEEEHHHHHHHHHHHHHHEEEEEEEEEECCCHHHHHH
LLTNAKNTIATLEEKAATGELSEIEAKRLASELMQSYAYSDNEYIWMTDEKLNFLAAPLD
HHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCC
PQIIGKHFSDIVSKEAETHIINNLTVAGQVITYSWFTTRENVTTEVKSIAVKTKLWNWYL
HHHHHHHHHHHHHHHHHHHHHHCEEEECEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
GSGVQEKKVNDTFKAFLFEGLTIGVIVNLFIGLVMFFAVRKYNKTLGNEPDVILNVIDRI
CCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SRGDLSHLPEKSIENVGIYSRILDMASNIKELVNDITVLTKELSDSSHHLSASSQTMNVN
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEE
VKTQTEQLEQAAVATDQIVVSVNEVTKSAVQATDSALTVNSTSADCISTIGDMNNDMQQL
EEEHHHHHHHHHHHHHHHEEEHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCHHHHHH
AGNIKGVAEVIGNLQVETENIGSILDVIRGIADQTNLLALNAAIEAARAGESGRGFAVVA
HHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCEEEEH
DEVRLLASRTQDSTAQISEMIAGLQDEAVKSVNLMQSNSDEAHTIAEKTVVAQNTVNSIF
HHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ESVSVIQTMNSQISASTEEQLVATTNVNQLITDINMFAKDNLTDVESTAQQAEKLGSMAD
HHHHHHHHHHHHHCCCCHHHEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DLTSIVNRFKL
HHHHHHHHHCC
>Mature Secondary Structure
MNSMMINGYFYLRPFMQFNTKSKYFIIYVIFSAAMFGSIIMGAYNVRFTLETNNVTRLEN
CCCEEEECEEEEEHHHHCCCCCCEEEEHHHHHHHHHHHHHHEEEEEEEEEECCCHHHHHH
LLTNAKNTIATLEEKAATGELSEIEAKRLASELMQSYAYSDNEYIWMTDEKLNFLAAPLD
HHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCC
PQIIGKHFSDIVSKEAETHIINNLTVAGQVITYSWFTTRENVTTEVKSIAVKTKLWNWYL
HHHHHHHHHHHHHHHHHHHHHHCEEEECEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
GSGVQEKKVNDTFKAFLFEGLTIGVIVNLFIGLVMFFAVRKYNKTLGNEPDVILNVIDRI
CCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SRGDLSHLPEKSIENVGIYSRILDMASNIKELVNDITVLTKELSDSSHHLSASSQTMNVN
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEE
VKTQTEQLEQAAVATDQIVVSVNEVTKSAVQATDSALTVNSTSADCISTIGDMNNDMQQL
EEEHHHHHHHHHHHHHHHEEEHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCHHHHHH
AGNIKGVAEVIGNLQVETENIGSILDVIRGIADQTNLLALNAAIEAARAGESGRGFAVVA
HHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCEEEEH
DEVRLLASRTQDSTAQISEMIAGLQDEAVKSVNLMQSNSDEAHTIAEKTVVAQNTVNSIF
HHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ESVSVIQTMNSQISASTEEQLVATTNVNQLITDINMFAKDNLTDVESTAQQAEKLGSMAD
HHHHHHHHHHHHHCCCCHHHEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DLTSIVNRFKL
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]