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The map label for this gene is htpG [H]

Identifier: 59711399

GI number: 59711399

Start: 865643

End: 867538

Strand: Direct

Name: htpG [H]

Synonym: VF_0792

Alternate gene names: 59711399

Gene position: 865643-867538 (Clockwise)

Preceding gene: 59711396

Following gene: 59711400

Centisome position: 29.88

GC content: 37.82

Gene sequence:

>1896_bases
ATGAGTGAGCAAACTGCTAATAAAGAAACACGTGGATTTCAATCAGAAGTAAAACAGTTACTTCATTTAATGATTCACTC
TTTATATTCAAATAAAGAGATCTTTTTGCGTGAACTAATCTCAAATGCTTCTGATGCATCAGATAAGTTACGTTTTAAAG
CGCTATCAAATGGCGACTTATATGAAGGTAATGCCGATCTTGGTGTTAAATTATCTTTTAACGAGGCTGCAAATACATTA
ACCATTTCAGATAATGGTATTGGTATGAGTCGTGAGGATGTGATTGAACATTTAGGTACGATTGCAAAATCGGGAACGGC
TGATTTTTTCTCTAAATTATCTGAAGATCAGAGTAAAGACTCTCAACTTATCGGTCAATTTGGTGTAGGTTTTTACTCTG
CATTTATTGTTGCTGATGCGGTTACGGTTCGTACGCGTGCTGCAGGTTCTGAAAAAGATCAAGGTGTTCAATGGCACTCA
GAGGGTGAAGGTGATTACACCATTGAAGACATTACAAAAGAAAGTCGCGGTACAGATATCATTCTTCATATGCGTGAAGA
AGGTAAAGAATTTCTAAATGAGTGGCGTTTAAAAGAAGTGATTGGTAAATACTCTGATCACATCGGTATCCCTGTCTCTA
TCTGGACTGTTGAAAAAGACGAAGAAGGAAAAGATAAAGAAGGTAAATGGGAACAAGTAAATAAAGCTCAAGCACTTTGG
ACTCGTAGTAAATCAGATATTGAAGATGCTGAATACCAAGAGTTCTATAAGCATGTTTCTCATGATTTTGCTGATCCATT
AACTTGGAGTCACAACAAAGTAGAAGGTAAAAATGACTACACGAGCCTTCTATATATTCCGGCAAAAGCACCATTTGATA
TGATGAACCGTGATCATAAAAGTGGTCTAAAACTATATGTTCAACGTGTCTTCATTATGGACGATGCTGAGCAATTTATG
CCAACGTATCTACGTTTTGTTAAGGGGTTAATTGACTCAAATGATTTACCTTTAAACGTATCGCGTGAGATTCTTCAAGA
TAATAAAGTAACTCAATCATTACGTAGTGCATGTACAAAACGTGTACTGGGTATGCTTGAGAAAATGGCGAAAAAAGACG
ATGAAAAGTACCTTACTTTCTGGAAACAATTTGGCCAAGTTTTAAAAGAAGGCTTAGCTGAAGACTTGGCTAATAAAGAA
AAAATTGCTGGGTTATTACGCTTTGCAACGACAGAAAAAGACAGTTCAGAGCAAGCTCTAGGTCTTGCTGGCTATGTTGA
GCGTATGAAAGAAGAACAAGATAAGATCTTCTATCTAACAGCTGACAGCTATGCTGCTGCGAAAAACAGTCCACACCTAG
AGCAATTTAAAGCAAAAGGTATTGAAGTTGTTCTGATGTATGACCGTATCGATGAGTGGCTAATGAGCTACTTAACCGAA
TTTGACGGTAAGCAATTCCAATCAATCACAAAAGCGGGCTTAGATTTAAGCAAGTTTGAAGATGAAGCGGAAAAAGAAAA
ACATAAAGAGACTGAAGAAGAGTTTAAGTCAGTTGTTGAGCGTACAAAGTCATATTTAGGCGATCGAGTTAAAGAAGTTC
GTACTACGTTCAAATTAGCAACGACACCAGCGGTTGTTGTTACTGATGACTTTGAAATGGGTACTCAAATGGCAAAACTG
TTGGAAGCTGCAGGTCAAGCTGCGCCAGAAGTGAAGTACATTTTTGAAATTAATCCAGACCATGCTTTAGTAAAACAAAT
GGCAGATGAAGCTGACGAAGAAGCATTTGGCCGTTGGGTTGAGATGTTACTTGGTCAAGCGATGCTTGCTGAACGAGGCT
CTTTAGAAGATCCGTCGCAGTTCTTAAGTGCAATGAATCAACTGCTAGCAAAATAA

Upstream 100 bases:

>100_bases
TGCCTGTTTTACATATCTTTACCTTGAATTGCTGTTTTATGACCCTATTTCAATATGTAAGTGTAAATAATGTTACCTCT
TAATATATTGGAGTTTTTAG

Downstream 100 bases:

>100_bases
CGATTATTTGTGCTAAATAAAATGAGACCTTAGTAAAGATAACACTAAGGTCTCATTGTCTTTAATGACGAAAATACACA
CAATTTAAGAGTCAGTTTTT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 631; Mature: 630

Protein sequence:

>631_residues
MSEQTANKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDASDKLRFKALSNGDLYEGNADLGVKLSFNEAANTL
TISDNGIGMSREDVIEHLGTIAKSGTADFFSKLSEDQSKDSQLIGQFGVGFYSAFIVADAVTVRTRAAGSEKDQGVQWHS
EGEGDYTIEDITKESRGTDIILHMREEGKEFLNEWRLKEVIGKYSDHIGIPVSIWTVEKDEEGKDKEGKWEQVNKAQALW
TRSKSDIEDAEYQEFYKHVSHDFADPLTWSHNKVEGKNDYTSLLYIPAKAPFDMMNRDHKSGLKLYVQRVFIMDDAEQFM
PTYLRFVKGLIDSNDLPLNVSREILQDNKVTQSLRSACTKRVLGMLEKMAKKDDEKYLTFWKQFGQVLKEGLAEDLANKE
KIAGLLRFATTEKDSSEQALGLAGYVERMKEEQDKIFYLTADSYAAAKNSPHLEQFKAKGIEVVLMYDRIDEWLMSYLTE
FDGKQFQSITKAGLDLSKFEDEAEKEKHKETEEEFKSVVERTKSYLGDRVKEVRTTFKLATTPAVVVTDDFEMGTQMAKL
LEAAGQAAPEVKYIFEINPDHALVKQMADEADEEAFGRWVEMLLGQAMLAERGSLEDPSQFLSAMNQLLAK

Sequences:

>Translated_631_residues
MSEQTANKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDASDKLRFKALSNGDLYEGNADLGVKLSFNEAANTL
TISDNGIGMSREDVIEHLGTIAKSGTADFFSKLSEDQSKDSQLIGQFGVGFYSAFIVADAVTVRTRAAGSEKDQGVQWHS
EGEGDYTIEDITKESRGTDIILHMREEGKEFLNEWRLKEVIGKYSDHIGIPVSIWTVEKDEEGKDKEGKWEQVNKAQALW
TRSKSDIEDAEYQEFYKHVSHDFADPLTWSHNKVEGKNDYTSLLYIPAKAPFDMMNRDHKSGLKLYVQRVFIMDDAEQFM
PTYLRFVKGLIDSNDLPLNVSREILQDNKVTQSLRSACTKRVLGMLEKMAKKDDEKYLTFWKQFGQVLKEGLAEDLANKE
KIAGLLRFATTEKDSSEQALGLAGYVERMKEEQDKIFYLTADSYAAAKNSPHLEQFKAKGIEVVLMYDRIDEWLMSYLTE
FDGKQFQSITKAGLDLSKFEDEAEKEKHKETEEEFKSVVERTKSYLGDRVKEVRTTFKLATTPAVVVTDDFEMGTQMAKL
LEAAGQAAPEVKYIFEINPDHALVKQMADEADEEAFGRWVEMLLGQAMLAERGSLEDPSQFLSAMNQLLAK
>Mature_630_residues
SEQTANKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDASDKLRFKALSNGDLYEGNADLGVKLSFNEAANTLT
ISDNGIGMSREDVIEHLGTIAKSGTADFFSKLSEDQSKDSQLIGQFGVGFYSAFIVADAVTVRTRAAGSEKDQGVQWHSE
GEGDYTIEDITKESRGTDIILHMREEGKEFLNEWRLKEVIGKYSDHIGIPVSIWTVEKDEEGKDKEGKWEQVNKAQALWT
RSKSDIEDAEYQEFYKHVSHDFADPLTWSHNKVEGKNDYTSLLYIPAKAPFDMMNRDHKSGLKLYVQRVFIMDDAEQFMP
TYLRFVKGLIDSNDLPLNVSREILQDNKVTQSLRSACTKRVLGMLEKMAKKDDEKYLTFWKQFGQVLKEGLAEDLANKEK
IAGLLRFATTEKDSSEQALGLAGYVERMKEEQDKIFYLTADSYAAAKNSPHLEQFKAKGIEVVLMYDRIDEWLMSYLTEF
DGKQFQSITKAGLDLSKFEDEAEKEKHKETEEEFKSVVERTKSYLGDRVKEVRTTFKLATTPAVVVTDDFEMGTQMAKLL
EAAGQAAPEVKYIFEINPDHALVKQMADEADEEAFGRWVEMLLGQAMLAERGSLEDPSQFLSAMNQLLAK

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI4507677, Length=630, Percent_Identity=36.984126984127, Blast_Score=409, Evalue=1e-114,
Organism=Homo sapiens, GI20149594, Length=671, Percent_Identity=37.25782414307, Blast_Score=407, Evalue=1e-113,
Organism=Homo sapiens, GI155722983, Length=637, Percent_Identity=36.2637362637363, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI154146191, Length=399, Percent_Identity=37.0927318295739, Blast_Score=257, Evalue=2e-68,
Organism=Homo sapiens, GI153792590, Length=399, Percent_Identity=37.0927318295739, Blast_Score=255, Evalue=1e-67,
Organism=Escherichia coli, GI1786679, Length=625, Percent_Identity=69.12, Blast_Score=887, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=676, Percent_Identity=37.2781065088757, Blast_Score=438, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17542208, Length=681, Percent_Identity=35.9765051395007, Blast_Score=401, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI115535205, Length=644, Percent_Identity=34.3167701863354, Blast_Score=330, Evalue=9e-91,
Organism=Caenorhabditis elegans, GI115535167, Length=426, Percent_Identity=37.5586854460094, Blast_Score=276, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6323840, Length=677, Percent_Identity=36.6322008862629, Blast_Score=421, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6325016, Length=209, Percent_Identity=44.9760765550239, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI17647529, Length=682, Percent_Identity=37.683284457478, Blast_Score=453, Evalue=1e-127,
Organism=Drosophila melanogaster, GI21357739, Length=681, Percent_Identity=37.5917767988253, Blast_Score=418, Evalue=1e-117,
Organism=Drosophila melanogaster, GI24586016, Length=640, Percent_Identity=33.90625, Blast_Score=361, Evalue=1e-100,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71628; Mature: 71497

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQTANKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDASDKLRFKALSNGDL
CCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHEEEEECCCCE
YEGNADLGVKLSFNEAANTLTISDNGIGMSREDVIEHLGTIAKSGTADFFSKLSEDQSKD
ECCCCCCEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHH
SQLIGQFGVGFYSAFIVADAVTVRTRAAGSEKDQGVQWHSEGEGDYTIEDITKESRGTDI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHCCCCCEE
ILHMREEGKEFLNEWRLKEVIGKYSDHIGIPVSIWTVEKDEEGKDKEGKWEQVNKAQALW
EEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHH
TRSKSDIEDAEYQEFYKHVSHDFADPLTWSHNKVEGKNDYTSLLYIPAKAPFDMMNRDHK
HCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHCCCHH
SGLKLYVQRVFIMDDAEQFMPTYLRFVKGLIDSNDLPLNVSREILQDNKVTQSLRSACTK
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RVLGMLEKMAKKDDEKYLTFWKQFGQVLKEGLAEDLANKEKIAGLLRFATTEKDSSEQAL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
GLAGYVERMKEEQDKIFYLTADSYAAAKNSPHLEQFKAKGIEVVLMYDRIDEWLMSYLTE
HHHHHHHHHHHCCCCEEEEECCCHHHCCCCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHH
FDGKQFQSITKAGLDLSKFEDEAEKEKHKETEEEFKSVVERTKSYLGDRVKEVRTTFKLA
HCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TTPAVVVTDDFEMGTQMAKLLEAAGQAAPEVKYIFEINPDHALVKQMADEADEEAFGRWV
CCCEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHH
EMLLGQAMLAERGSLEDPSQFLSAMNQLLAK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEQTANKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDASDKLRFKALSNGDL
CCCCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHEEEEECCCCE
YEGNADLGVKLSFNEAANTLTISDNGIGMSREDVIEHLGTIAKSGTADFFSKLSEDQSKD
ECCCCCCEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHH
SQLIGQFGVGFYSAFIVADAVTVRTRAAGSEKDQGVQWHSEGEGDYTIEDITKESRGTDI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHCCCCCEE
ILHMREEGKEFLNEWRLKEVIGKYSDHIGIPVSIWTVEKDEEGKDKEGKWEQVNKAQALW
EEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHH
TRSKSDIEDAEYQEFYKHVSHDFADPLTWSHNKVEGKNDYTSLLYIPAKAPFDMMNRDHK
HCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHCCCHH
SGLKLYVQRVFIMDDAEQFMPTYLRFVKGLIDSNDLPLNVSREILQDNKVTQSLRSACTK
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RVLGMLEKMAKKDDEKYLTFWKQFGQVLKEGLAEDLANKEKIAGLLRFATTEKDSSEQAL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
GLAGYVERMKEEQDKIFYLTADSYAAAKNSPHLEQFKAKGIEVVLMYDRIDEWLMSYLTE
HHHHHHHHHHHCCCCEEEEECCCHHHCCCCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHH
FDGKQFQSITKAGLDLSKFEDEAEKEKHKETEEEFKSVVERTKSYLGDRVKEVRTTFKLA
HCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TTPAVVVTDDFEMGTQMAKLLEAAGQAAPEVKYIFEINPDHALVKQMADEADEEAFGRWV
CCCEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHH
EMLLGQAMLAERGSLEDPSQFLSAMNQLLAK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA