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The map label for this gene is luxP [H]

Identifier: 59711314

GI number: 59711314

Start: 773743

End: 774861

Strand: Direct

Name: luxP [H]

Synonym: VF_0707

Alternate gene names: 59711314

Gene position: 773743-774861 (Clockwise)

Preceding gene: 59711313

Following gene: 59711315

Centisome position: 26.7

GC content: 35.12

Gene sequence:

>1119_bases
ATGCGCAACGGTAGATTATTATTAAGCTTCCTATTTATATCGCTTATTTCATTTTTTTGTACCTCTAAACTGGTTTTAGC
TGATCCTGTTTTAGTTGGATATTGGGGCTATAATGAATATCTTGATCTATATCCTGAAGAAAAAGCACTAACTAATACGT
TAAAAGAAACGGTTAGAGGGGAGCCTGTCCCTCTAGCTATCAAGCAAACAAAACCAATTAAAATATCTTTTGTTTATCCT
GGTGAGCAATCATCTGATTATTGGCAACGAAATATTGTTGCTCTTGAATCACGTCTGAAAGCGTTAAATATTCAATATGA
ACTAACGCCTGTTTCAACACGTCTAAATGTTGATTTTAAAGAACAAAGTCGTTCTCTGCATAAAGCGATAGAGCAAAAAT
CGGATTATTTAATTTTTACTCTTAACACGACTCGTCATCGTAAATTTATTGAACATGTATTGCAGAATCCAGAAACGAAG
ATTATTTTGCAAAACATCACTACTCCAGTAAAAGCATGGCATGGTAGCCAACCATTACTTTATGTGGGATTTGACCATGT
TATTGGCACTAAATTATTAGCAAACTATTTTCAGCACCGTTTTCCTGAACACGCTAATTATGGAATGCTATATTATTCAT
ATGGCTATTTGAGTACTGCAAGAGGTGATGTTTTTGTTCAATCTATGGATAGTGATAAATACACACTGACTTCTTCTTTT
TATACCGAAGCGACTGAAGAGAGCGCTTATGCTGCAACACAAGATATATTAAAAGATAATCCTGATATTGATTTTATCTA
TTCTTCATCTACAGATATTGCTTTAGGTGCTATTGATGCAATTAATGATAATAAGAATACTAAGACCGTAATTAATGGTT
GGGGCGGTGGTTCATTAGAGTTAAAAGCCATAGAAAATGGGGAGCTCGATGTTACTGTTATGCGTATGACTGATGACACA
GGTATAGCAATGGCAGAAGCAATTAAACTAGATTTAGAGAACAAACCTGTGGCTACTGTTTATTCTGGCGAGTTTGAACT
GGTTACATCTGATACGAGTGAAGAAACACTTAATACGCTAAAACAGCGTGCGTTTCGTTATTCTGGTGTAGAACACTAG

Upstream 100 bases:

>100_bases
AAGTTCATGGCGGCTTTGGCATCATGCTTGATGATATTGTTGCTGGATTTATGGCTCTAATTAGCCTTTGGTTAGTTGGA
AAGTATTCTGGTTGGTTGTA

Downstream 100 bases:

>100_bases
TAATGAATAAAGGTAAAGCCTCGTTAGCGGATCTTATTTTTCGATCAATTTTTATTATATTTTCTATTTTAACAGTAGGT
ATAACCATACATACCTACCA

Product: periplasmic AI-2 binding protein LuxP

Products: ADP; phosphate; ribose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MRNGRLLLSFLFISLISFFCTSKLVLADPVLVGYWGYNEYLDLYPEEKALTNTLKETVRGEPVPLAIKQTKPIKISFVYP
GEQSSDYWQRNIVALESRLKALNIQYELTPVSTRLNVDFKEQSRSLHKAIEQKSDYLIFTLNTTRHRKFIEHVLQNPETK
IILQNITTPVKAWHGSQPLLYVGFDHVIGTKLLANYFQHRFPEHANYGMLYYSYGYLSTARGDVFVQSMDSDKYTLTSSF
YTEATEESAYAATQDILKDNPDIDFIYSSSTDIALGAIDAINDNKNTKTVINGWGGGSLELKAIENGELDVTVMRMTDDT
GIAMAEAIKLDLENKPVATVYSGEFELVTSDTSEETLNTLKQRAFRYSGVEH

Sequences:

>Translated_372_residues
MRNGRLLLSFLFISLISFFCTSKLVLADPVLVGYWGYNEYLDLYPEEKALTNTLKETVRGEPVPLAIKQTKPIKISFVYP
GEQSSDYWQRNIVALESRLKALNIQYELTPVSTRLNVDFKEQSRSLHKAIEQKSDYLIFTLNTTRHRKFIEHVLQNPETK
IILQNITTPVKAWHGSQPLLYVGFDHVIGTKLLANYFQHRFPEHANYGMLYYSYGYLSTARGDVFVQSMDSDKYTLTSSF
YTEATEESAYAATQDILKDNPDIDFIYSSSTDIALGAIDAINDNKNTKTVINGWGGGSLELKAIENGELDVTVMRMTDDT
GIAMAEAIKLDLENKPVATVYSGEFELVTSDTSEETLNTLKQRAFRYSGVEH
>Mature_372_residues
MRNGRLLLSFLFISLISFFCTSKLVLADPVLVGYWGYNEYLDLYPEEKALTNTLKETVRGEPVPLAIKQTKPIKISFVYP
GEQSSDYWQRNIVALESRLKALNIQYELTPVSTRLNVDFKEQSRSLHKAIEQKSDYLIFTLNTTRHRKFIEHVLQNPETK
IILQNITTPVKAWHGSQPLLYVGFDHVIGTKLLANYFQHRFPEHANYGMLYYSYGYLSTARGDVFVQSMDSDKYTLTSSF
YTEATEESAYAATQDILKDNPDIDFIYSSSTDIALGAIDAINDNKNTKTVINGWGGGSLELKAIENGELDVTVMRMTDDT
GIAMAEAIKLDLENKPVATVYSGEFELVTSDTSEETLNTLKQRAFRYSGVEH

Specific function: Binds to the signaling molecule autoinducer 2 (AI-2), a furanosyl borate diester, (3a-methyl-5,6-dihydrofuro- [2,3d][1,3,2]dioxaborole-2,2,6,6a-tetraol). This complex then interacts with the luxQ sensor protein [H]

COG id: COG1879

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: 3940 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5900 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 1520 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 42180; Mature: 42180

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNGRLLLSFLFISLISFFCTSKLVLADPVLVGYWGYNEYLDLYPEEKALTNTLKETVRG
CCCCHHHHHHHHHHHHHHHHCCCEEEECCEEEEECCCCCCEECCCCHHHHHHHHHHHHCC
EPVPLAIKQTKPIKISFVYPGEQSSDYWQRNIVALESRLKALNIQYELTPVSTRLNVDFK
CCCEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEEEEEEEEEEEEEECCHH
EQSRSLHKAIEQKSDYLIFTLNTTRHRKFIEHVLQNPETKIILQNITTPVKAWHGSQPLL
HHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHCCCCCEE
YVGFDHVIGTKLLANYFQHRFPEHANYGMLYYSYGYLSTARGDVFVQSMDSDKYTLTSSF
EEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECEEEECCCCEEEEECCCCCEEEEEHH
YTEATEESAYAATQDILKDNPDIDFIYSSSTDIALGAIDAINDNKNTKTVINGWGGGSLE
HHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEECCCCCCCEEEEEECCCCEEE
LKAIENGELDVTVMRMTDDTGIAMAEAIKLDLENKPVATVYSGEFELVTSDTSEETLNTL
EEEECCCCEEEEEEEEECCCCHHEEEEEEEECCCCCEEEEECCEEEEEECCCCHHHHHHH
KQRAFRYSGVEH
HHHHHHHCCCCC
>Mature Secondary Structure
MRNGRLLLSFLFISLISFFCTSKLVLADPVLVGYWGYNEYLDLYPEEKALTNTLKETVRG
CCCCHHHHHHHHHHHHHHHHCCCEEEECCEEEEECCCCCCEECCCCHHHHHHHHHHHHCC
EPVPLAIKQTKPIKISFVYPGEQSSDYWQRNIVALESRLKALNIQYELTPVSTRLNVDFK
CCCEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEEEEEEEEEEEEEECCHH
EQSRSLHKAIEQKSDYLIFTLNTTRHRKFIEHVLQNPETKIILQNITTPVKAWHGSQPLL
HHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHCCCCCEE
YVGFDHVIGTKLLANYFQHRFPEHANYGMLYYSYGYLSTARGDVFVQSMDSDKYTLTSSF
EEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECEEEECCCCEEEEECCCCCEEEEEHH
YTEATEESAYAATQDILKDNPDIDFIYSSSTDIALGAIDAINDNKNTKTVINGWGGGSLE
HHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEECCCCCCCEEEEEECCCCEEE
LKAIENGELDVTVMRMTDDTGIAMAEAIKLDLENKPVATVYSGEFELVTSDTSEETLNTL
EEEECCCCEEEEEEEEECCCCHHEEEEEEEECCCCCEEEEECCEEEEEECCCCHHHHHHH
KQRAFRYSGVEH
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ribose [Periplasm]; H2O [C]

Specific reaction: ATP + ribose [Periplasm] + H2O = ADP + phosphate + ribose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7984107; 11823863 [H]