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The map label for this gene is nanE [H]

Identifier: 59711273

GI number: 59711273

Start: 730087

End: 730824

Strand: Direct

Name: nanE [H]

Synonym: VF_0666

Alternate gene names: 59711273

Gene position: 730087-730824 (Clockwise)

Preceding gene: 59711271

Following gene: 59711274

Centisome position: 25.2

GC content: 40.79

Gene sequence:

>738_bases
ATGTTGCTATTAAGTTTGGAGTTCAGCTTTATGGGAAGCAATATCGACAAGACATTAAATGCATTATCTCAAGGCTTCGT
TTCATCATGTCAGCCAGTTGATGATGGCCCAATGGATAAACCTGAAATTGTTGCTGCTATGGCAATGGCAAGTGTTGAAG
GTGGCGCAATTGGTTTACGAATTGAAGGCATTGATAATTTAAAAGCAGTAAGACCACATGTATCGGTTCCAATTATTGGC
ATTATTAAGCGTGATCTTGATGACTCTGAGGTTCGGATTACACCTTATATCGAGGACGTAATTGCATTAAAAGAAGCTGG
GGCAGATATCATTGCAATTGATGCGACTCACCGACCTCGACCTGTACCCGTCGAAGAATTAGTAAAGAAAATTCAAAGCT
TAGGTTGTTTAGTCATGGCGGACTCTTCGACTTATGAAGAGGGAATGTTTTGTCATGGACTCGGTGTTGAAATTATAGGT
ACCACATTATCTGGATACACCACACCAGTCACTCCAAAAGAACCGGATTTCCCGTTCATTCAACAATTAGCAAATCAAGG
GTGTTTTGTTATGGCTGAAGGGCGTTTTAATTCACCACAATTGGCTAGAGAAGCAATAGAAGCGGGAGCATCTTGCGTCA
CTGTTGGTTCAGCGATTACACGTATTGAGCATATTTGTGGTTGGTTTAAATCTGAAGTTGAACTAGGTAAGAAAAACATG
GTTAAGGACATCGCATGA

Upstream 100 bases:

>100_bases
CCAATTTTATTGGTTCTATTTTTAAAGAGATCTAGATCTCCATTTTTATATCTTTAGATTGAAGTATTACTCCGTTGGTG
TAGTTTGGAGTAATACTATT

Downstream 100 bases:

>100_bases
AGCCTTGCTTAACGGTTGATATTGGTGGAACTAAAATTGCAGCGGCAATCATTGAATCTGGAAAAGTGCTACGCCGTCAG
CAAATTGCGACACCATCGTC

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MLLLSLEFSFMGSNIDKTLNALSQGFVSSCQPVDDGPMDKPEIVAAMAMASVEGGAIGLRIEGIDNLKAVRPHVSVPIIG
IIKRDLDDSEVRITPYIEDVIALKEAGADIIAIDATHRPRPVPVEELVKKIQSLGCLVMADSSTYEEGMFCHGLGVEIIG
TTLSGYTTPVTPKEPDFPFIQQLANQGCFVMAEGRFNSPQLAREAIEAGASCVTVGSAITRIEHICGWFKSEVELGKKNM
VKDIA

Sequences:

>Translated_245_residues
MLLLSLEFSFMGSNIDKTLNALSQGFVSSCQPVDDGPMDKPEIVAAMAMASVEGGAIGLRIEGIDNLKAVRPHVSVPIIG
IIKRDLDDSEVRITPYIEDVIALKEAGADIIAIDATHRPRPVPVEELVKKIQSLGCLVMADSSTYEEGMFCHGLGVEIIG
TTLSGYTTPVTPKEPDFPFIQQLANQGCFVMAEGRFNSPQLAREAIEAGASCVTVGSAITRIEHICGWFKSEVELGKKNM
VKDIA
>Mature_245_residues
MLLLSLEFSFMGSNIDKTLNALSQGFVSSCQPVDDGPMDKPEIVAAMAMASVEGGAIGLRIEGIDNLKAVRPHVSVPIIG
IIKRDLDDSEVRITPYIEDVIALKEAGADIIAIDATHRPRPVPVEELVKKIQSLGCLVMADSSTYEEGMFCHGLGVEIIG
TTLSGYTTPVTPKEPDFPFIQQLANQGCFVMAEGRFNSPQLAREAIEAGASCVTVGSAITRIEHICGWFKSEVELGKKNM
VKDIA

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential) [H]

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family [H]

Homologues:

Organism=Escherichia coli, GI1789617, Length=214, Percent_Identity=61.6822429906542, Blast_Score=263, Evalue=7e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060 [H]

Pfam domain/function: PF04131 NanE [H]

EC number: =5.1.3.9 [H]

Molecular weight: Translated: 26335; Mature: 26335

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLSLEFSFMGSNIDKTLNALSQGFVSSCQPVDDGPMDKPEIVAAMAMASVEGGAIGLR
CEEEEEEHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEE
IEGIDNLKAVRPHVSVPIIGIIKRDLDDSEVRITPYIEDVIALKEAGADIIAIDATHRPR
ECCCCCCHHCCCCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCCC
PVPVEELVKKIQSLGCLVMADSSTYEEGMFCHGLGVEIIGTTLSGYTTPVTPKEPDFPFI
CCCHHHHHHHHHHCCEEEEECCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCHHH
QQLANQGCFVMAEGRFNSPQLAREAIEAGASCVTVGSAITRIEHICGWFKSEVELGKKNM
HHHHCCCCEEEECCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCHHHH
VKDIA
HHHCC
>Mature Secondary Structure
MLLLSLEFSFMGSNIDKTLNALSQGFVSSCQPVDDGPMDKPEIVAAMAMASVEGGAIGLR
CEEEEEEHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEE
IEGIDNLKAVRPHVSVPIIGIIKRDLDDSEVRITPYIEDVIALKEAGADIIAIDATHRPR
ECCCCCCHHCCCCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCCC
PVPVEELVKKIQSLGCLVMADSSTYEEGMFCHGLGVEIIGTTLSGYTTPVTPKEPDFPFI
CCCHHHHHHHHHHCCEEEEECCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCHHH
QQLANQGCFVMAEGRFNSPQLAREAIEAGASCVTVGSAITRIEHICGWFKSEVELGKKNM
HHHHCCCCEEEECCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCHHHH
VKDIA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA