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The map label for this gene is rpiR [C]

Identifier: 59711271

GI number: 59711271

Start: 727762

End: 728640

Strand: Direct

Name: rpiR [C]

Synonym: VF_0664

Alternate gene names: 59711271

Gene position: 727762-728640 (Clockwise)

Preceding gene: 59711267

Following gene: 59711273

Centisome position: 25.12

GC content: 37.09

Gene sequence:

>879_bases
ATGTCCAACCATAATATTCAAATAAAAGCGGGCAACATCATCGATACGATAGGCAGTCTTTATAATAGTTTGACTCCATC
TTCAAAGCGTATCGCTGATTATGTTATGTCTAATGCGACTCAAGTGAGTAAACACTCGATTGCTGAACTATCACAGATTG
TAAATGCGGGTGATGCAACCATTATTCGTTTTTGTCGAACTCTTGGTTTTAAGGGCTATCAAGATTTTAAAATGGAATTG
GCGATTGAAGTTTCTAATCTTCAAGGTCGAGAAAAAGAGATTTTTGATACTGATGTTACTGCGGAAGATAATGCGGAAGT
GATAGGGCATAAGCTTCAATCAACCATTGAAAGCGTCCTTGCTGAAACCATGAATTTACTTAACTTCCAATCTTTAGAGT
CGGTAGCTGAAGCATTAAAAGATGCAAAAGCGATTTACTTTTTTGGTGTTGGTTCATCAGGTTTAACCGCTGAAAGTGCA
AAACATAAATTCATGCGAATTGGTTTAAATGTGGATGCATTTACTAATAACCATTTTATGTATATTAAATCATCGTTAAT
GCAACCTGGGGATTTCGCAGTAGGGCTTAGTCACTCTGGTAATTCAGTTGAAACGACAAAAGCATTACGCTTAGCAAAAG
AGAGTGGAGCGACGACGATTGCCATTACGCATAATCCTCGTTCGGATATTACTAAGTATTCTGATTATGTCTTAGTGAAC
GGTAATAGGCAGGGACAACTGCAAGGTGACTCTATTGGTACTAAAATATCGCAGTTGTTCGTATTGGATTTAATTTATAC
TTTATTAGTGAAGCGTGATATTAGTGGTGCAAAAGCTAATAAACTCAAGACTACAGAAGCGCTTTCTAACCAATCGTAA

Upstream 100 bases:

>100_bases
TAAATAATGCGAATAATAATTATGGAGTTACACTTCACAAAGTGGGAGTAGCATGACAAAATGAAATTCACAACGTGTTT
TATTCAAGGGTTACTTTCTG

Downstream 100 bases:

>100_bases
TTCTTTGACTGTATAAAATTATAAGGCCGTGAATATACACATATTCACGGCCTATTTTTTATTTCTGATAAACCAATTTA
CCCATTTGAATCGTTGTTGT

Product: DNA-binding transcriptional repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSNHNIQIKAGNIIDTIGSLYNSLTPSSKRIADYVMSNATQVSKHSIAELSQIVNAGDATIIRFCRTLGFKGYQDFKMEL
AIEVSNLQGREKEIFDTDVTAEDNAEVIGHKLQSTIESVLAETMNLLNFQSLESVAEALKDAKAIYFFGVGSSGLTAESA
KHKFMRIGLNVDAFTNNHFMYIKSSLMQPGDFAVGLSHSGNSVETTKALRLAKESGATTIAITHNPRSDITKYSDYVLVN
GNRQGQLQGDSIGTKISQLFVLDLIYTLLVKRDISGAKANKLKTTEALSNQS

Sequences:

>Translated_292_residues
MSNHNIQIKAGNIIDTIGSLYNSLTPSSKRIADYVMSNATQVSKHSIAELSQIVNAGDATIIRFCRTLGFKGYQDFKMEL
AIEVSNLQGREKEIFDTDVTAEDNAEVIGHKLQSTIESVLAETMNLLNFQSLESVAEALKDAKAIYFFGVGSSGLTAESA
KHKFMRIGLNVDAFTNNHFMYIKSSLMQPGDFAVGLSHSGNSVETTKALRLAKESGATTIAITHNPRSDITKYSDYVLVN
GNRQGQLQGDSIGTKISQLFVLDLIYTLLVKRDISGAKANKLKTTEALSNQS
>Mature_291_residues
SNHNIQIKAGNIIDTIGSLYNSLTPSSKRIADYVMSNATQVSKHSIAELSQIVNAGDATIIRFCRTLGFKGYQDFKMELA
IEVSNLQGREKEIFDTDVTAEDNAEVIGHKLQSTIESVLAETMNLLNFQSLESVAEALKDAKAIYFFGVGSSGLTAESAK
HKFMRIGLNVDAFTNNHFMYIKSSLMQPGDFAVGLSHSGNSVETTKALRLAKESGATTIAITHNPRSDITKYSDYVLVNG
NRQGQLQGDSIGTKISQLFVLDLIYTLLVKRDISGAKANKLKTTEALSNQS

Specific function: Regulatory Protein Involved In Rpib Gene Repression. Also Involved In Als Operon Repression. [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI87082369, Length=261, Percent_Identity=24.1379310344828, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788767, Length=255, Percent_Identity=27.0588235294118, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788159, Length=214, Percent_Identity=28.0373831775701, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI87082130, Length=268, Percent_Identity=22.7611940298507, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31839; Mature: 31708

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNHNIQIKAGNIIDTIGSLYNSLTPSSKRIADYVMSNATQVSKHSIAELSQIVNAGDAT
CCCCEEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHH
IIRFCRTLGFKGYQDFKMELAIEVSNLQGREKEIFDTDVTAEDNAEVIGHKLQSTIESVL
HHHHHHHHCCCCCCCEEEEEEEEECCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
AETMNLLNFQSLESVAEALKDAKAIYFFGVGSSGLTAESAKHKFMRIGLNVDAFTNNHFM
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHCEEEEECCCEEEEECCEEE
YIKSSLMQPGDFAVGLSHSGNSVETTKALRLAKESGATTIAITHNPRSDITKYSDYVLVN
EEEHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCEEEEE
GNRQGQLQGDSIGTKISQLFVLDLIYTLLVKRDISGAKANKLKTTEALSNQS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
SNHNIQIKAGNIIDTIGSLYNSLTPSSKRIADYVMSNATQVSKHSIAELSQIVNAGDAT
CCCEEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHH
IIRFCRTLGFKGYQDFKMELAIEVSNLQGREKEIFDTDVTAEDNAEVIGHKLQSTIESVL
HHHHHHHHCCCCCCCEEEEEEEEECCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
AETMNLLNFQSLESVAEALKDAKAIYFFGVGSSGLTAESAKHKFMRIGLNVDAFTNNHFM
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHCEEEEECCCEEEEECCEEE
YIKSSLMQPGDFAVGLSHSGNSVETTKALRLAKESGATTIAITHNPRSDITKYSDYVLVN
EEEHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCEEEEE
GNRQGQLQGDSIGTKISQLFVLDLIYTLLVKRDISGAKANKLKTTEALSNQS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]