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The map label for this gene is yneH [H]

Identifier: 59711030

GI number: 59711030

Start: 453108

End: 454028

Strand: Direct

Name: yneH [H]

Synonym: VF_0423

Alternate gene names: 59711030

Gene position: 453108-454028 (Clockwise)

Preceding gene: 172087664

Following gene: 59711038

Centisome position: 15.64

GC content: 39.96

Gene sequence:

>921_bases
ATGAAGCCAACAAAACAAATACTCGAAGATATTTTGGATGAAGTTCGTCCTCTTATTGGTCAAGGTAAAGTTGCTGATTA
CATTCCTGCTCTTGCTTGCGTTCCTAATGATAAATTGGGTATTGCAGTATTTACCAATGATGGTGAAATGCTCACAGCAG
GCGATGCGACAGAGTGTTTTTCTATTCAATCTATTTCAAAAGCGCTCAGTTTGACGTTGGCGATGGAACTGTATCAACCA
GAAGAGTTATGGCAACGAGTTGGTAAAGAGCCTTCAGGACAAGCATTTAATTCTCTTATTCAGCTTGAAATGGAACAAGG
TGTGCCTCGCAATCCTTTCATAAATGCTGGGGCGATTGTTATTTCAGATATGCTATACAGTCGCTTTTCTGCTCCAAAGC
ACCGATTATTAGAGTTTGTGCGTAAGCTCTCAGGTAATGACCATATTATTTATGATCGCGTGGTGGCTAATTCAGAAATG
GATCATAGTGATAGAAATGCTTCTATTGCTTATTTAATGCGTTCATTTGGTAACTTCGATAATGAAGTGATGCCTGTCTT
AAAGAACTATTTTCATGCATGTGCATTGAGTATGAACTGCGTGGATTTAGCTCGTACTTTTGGTTATTTAGCCAATAAAG
GTATTCAACCTGGGATCAGTGAACCTATTGTTACTCCAATGCAATGTAAGCAAATTAATGCATTAATGGCGACTTGTGGT
TTATATGATGGTGCAGGTGAGTTTGCTTATCGTGTTGGTATGCCAGGAAAGTCAGGTGTTGGTGGTGGCATTATTGCTAT
CGTTCCTGGCGAAATGACTATTGCAGTATGGTCTCCAGAGCTTGATCCATCAGGGAATTCGCTGGCAGGTACTAAAGCAT
TAGAGCTGCTTTCAGAACGTATTGGTCGTTCGATATTTTAA

Upstream 100 bases:

>100_bases
TCCGTCGTAACGCATAGTTAGTATTGTCGTAATACAATATAATTAAAGCCAACCTGAGTGTTGGCTTTTTTGTCCTTGCT
GTCAAAAGGAAGTAGAAATA

Downstream 100 bases:

>100_bases
GGTAAGAGCAGGGTTAAGGACGGTCGCAAGCTCCCTAAAGGTTTCAGGAAAAGATTCTTTGCTCTTACTGAAACCTTTAA
GCGAAGCGATCTGAAGCCGG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MKPTKQILEDILDEVRPLIGQGKVADYIPALACVPNDKLGIAVFTNDGEMLTAGDATECFSIQSISKALSLTLAMELYQP
EELWQRVGKEPSGQAFNSLIQLEMEQGVPRNPFINAGAIVISDMLYSRFSAPKHRLLEFVRKLSGNDHIIYDRVVANSEM
DHSDRNASIAYLMRSFGNFDNEVMPVLKNYFHACALSMNCVDLARTFGYLANKGIQPGISEPIVTPMQCKQINALMATCG
LYDGAGEFAYRVGMPGKSGVGGGIIAIVPGEMTIAVWSPELDPSGNSLAGTKALELLSERIGRSIF

Sequences:

>Translated_306_residues
MKPTKQILEDILDEVRPLIGQGKVADYIPALACVPNDKLGIAVFTNDGEMLTAGDATECFSIQSISKALSLTLAMELYQP
EELWQRVGKEPSGQAFNSLIQLEMEQGVPRNPFINAGAIVISDMLYSRFSAPKHRLLEFVRKLSGNDHIIYDRVVANSEM
DHSDRNASIAYLMRSFGNFDNEVMPVLKNYFHACALSMNCVDLARTFGYLANKGIQPGISEPIVTPMQCKQINALMATCG
LYDGAGEFAYRVGMPGKSGVGGGIIAIVPGEMTIAVWSPELDPSGNSLAGTKALELLSERIGRSIF
>Mature_306_residues
MKPTKQILEDILDEVRPLIGQGKVADYIPALACVPNDKLGIAVFTNDGEMLTAGDATECFSIQSISKALSLTLAMELYQP
EELWQRVGKEPSGQAFNSLIQLEMEQGVPRNPFINAGAIVISDMLYSRFSAPKHRLLEFVRKLSGNDHIIYDRVVANSEM
DHSDRNASIAYLMRSFGNFDNEVMPVLKNYFHACALSMNCVDLARTFGYLANKGIQPGISEPIVTPMQCKQINALMATCG
LYDGAGEFAYRVGMPGKSGVGGGIIAIVPGEMTIAVWSPELDPSGNSLAGTKALELLSERIGRSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=273, Percent_Identity=36.6300366300366, Blast_Score=185, Evalue=6e-47,
Organism=Homo sapiens, GI20336214, Length=294, Percent_Identity=34.0136054421769, Blast_Score=171, Evalue=9e-43,
Organism=Escherichia coli, GI1787804, Length=300, Percent_Identity=68, Blast_Score=428, Evalue=1e-121,
Organism=Escherichia coli, GI1786693, Length=303, Percent_Identity=36.6336633663366, Blast_Score=193, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17507019, Length=297, Percent_Identity=39.0572390572391, Blast_Score=197, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI193204073, Length=294, Percent_Identity=38.0952380952381, Blast_Score=188, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI193204075, Length=296, Percent_Identity=37.8378378378378, Blast_Score=187, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17532727, Length=293, Percent_Identity=34.8122866894198, Blast_Score=177, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24653162, Length=298, Percent_Identity=34.5637583892617, Blast_Score=184, Evalue=8e-47,
Organism=Drosophila melanogaster, GI281363241, Length=298, Percent_Identity=34.5637583892617, Blast_Score=184, Evalue=9e-47,
Organism=Drosophila melanogaster, GI116008307, Length=298, Percent_Identity=34.5637583892617, Blast_Score=184, Evalue=9e-47,
Organism=Drosophila melanogaster, GI24653156, Length=298, Percent_Identity=34.5637583892617, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24653166, Length=298, Percent_Identity=34.5637583892617, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24653158, Length=298, Percent_Identity=34.5637583892617, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24653164, Length=298, Percent_Identity=34.5637583892617, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI281363239, Length=298, Percent_Identity=34.5637583892617, Blast_Score=183, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 33315; Mature: 33315

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTKQILEDILDEVRPLIGQGKVADYIPALACVPNDKLGIAVFTNDGEMLTAGDATECF
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEECCCCEEECCCCHHHH
SIQSISKALSLTLAMELYQPEELWQRVGKEPSGQAFNSLIQLEMEQGVPRNPFINAGAIV
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHH
ISDMLYSRFSAPKHRLLEFVRKLSGNDHIIYDRVVANSEMDHSDRNASIAYLMRSFGNFD
HHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCHHHHHHHHHHCCCC
NEVMPVLKNYFHACALSMNCVDLARTFGYLANKGIQPGISEPIVTPMQCKQINALMATCG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
LYDGAGEFAYRVGMPGKSGVGGGIIAIVPGEMTIAVWSPELDPSGNSLAGTKALELLSER
CCCCCCCCEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
IGRSIF
HCCCCC
>Mature Secondary Structure
MKPTKQILEDILDEVRPLIGQGKVADYIPALACVPNDKLGIAVFTNDGEMLTAGDATECF
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEECCCCEEECCCCHHHH
SIQSISKALSLTLAMELYQPEELWQRVGKEPSGQAFNSLIQLEMEQGVPRNPFINAGAIV
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHH
ISDMLYSRFSAPKHRLLEFVRKLSGNDHIIYDRVVANSEMDHSDRNASIAYLMRSFGNFD
HHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCHHHHHHHHHHCCCC
NEVMPVLKNYFHACALSMNCVDLARTFGYLANKGIQPGISEPIVTPMQCKQINALMATCG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
LYDGAGEFAYRVGMPGKSGVGGGIIAIVPGEMTIAVWSPELDPSGNSLAGTKALELLSER
CCCCCCCCEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
IGRSIF
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA