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The map label for this gene is murA [H]

Identifier: 59711008

GI number: 59711008

Start: 430383

End: 431651

Strand: Direct

Name: murA [H]

Synonym: VF_0401

Alternate gene names: 59711008

Gene position: 430383-431651 (Clockwise)

Preceding gene: 59711007

Following gene: 59711009

Centisome position: 14.85

GC content: 42.47

Gene sequence:

>1269_bases
ATGTATAAGTTTCGAATTCAAGGAAGTGATAAACCACTTTCTGGCGAAGTTACAATTTCTGGTGCAAAAAATGCTGCACT
ACCAATTCTATTTGCTTCGTTACTTGCAGAAGAACCTGTTGAAGTAGCAAACGTACCGAAACTTCGTGATGTTGACACCA
CGATGGAACTGTTAAAGCGTTTAGGTGCTGAAGTATCTCGTAACGGTTCTGTTCATATTGATGCAAGTGGCGTAAATGAC
TTCTGCGCACCTTATGATTTAGTGAAAACAATGCGTGCATCAATTTGGGCATTAGGTCCATTGGTTGCTCGTTTTGGTAA
AGGTCAGGTTTCATTACCTGGTGGTTGTGCTATCGGTGCTCGTCCTGTTGATCTTCATATTCACGGATTAGAGCAACTAG
GTGCAACAATCAAACTTGAAGAAGGTTATGTAAAAGCGGAAGTTGATGGTCGCCTTAAAGGTGCTCATATCGTAATGGAC
AAAGTAAGTGTTGGTGCAACAATTACTGTTATGTGTGCAGCAACATTGGCTGAAGGCACGACGGTATTAGAAAACGCAGC
ACGTGAACCTGAAATTGTTGATACTGCTAACTTCCTTAATGCTATCGGCGCTAAAGTGTCTGGTATGGGTACCGATACTA
TTACTATCGAAGGTGTTGAACGCCTAGGTGGTGGTTATCACGAAGTGGTTGCTGACCGTATTGAGACCGGTACGTTCCTT
GTTGCTGCTGCAGTATCTGGCGGTAAGATTGTTTGTAAGAATACTAAAGCACATCTACTTGAAGCGGTACTTGCTAAGCT
TGAAGAAGCGGGTGCAGACGTTCAGACTGGTGATGATTGGATTAGCTTAGATATGACTGGCCGTGAGTTAAAGGCGGTAA
ATATCCGTACTGCACCACACCCAGCATTCCCTACAGATATGCAAGCTCAATTCACACTTTTAAATATGATGGCTAAAGGT
TCAGGTATCATTACTGAAACGATTTTCGAAAACCGTTTCATGCACATTCCTGAACTGCAACGTATGGGTGCTCACGCTGA
AATCGAAGGTAATACTGCTATTTGTGGTGACACTGATGGTTTAAGTGGTGCTCAGGTTATGGCGACAGATTTACGTGCAT
CAGCAAGCCTTGTGATCGCAGGTTGTATAGCAAAAGGTGAAACAATTGTTGATCGAATTTATCATATCGCCCGTGGATAT
GATAAGATTGAAGATAAGTTAACCGCTTTAGGTGCAAATATTGAGCGAGTTCATAGCGACGACTTATAA

Upstream 100 bases:

>100_bases
TCTCAACGAATACAATTCATGCTCTATCAATAAAAGCGTTTACTCCTGAAGAGTGGGCACGTGATAAAAAATTAAATAGC
TTATTCTAAGAGGCCCTTTG

Downstream 100 bases:

>100_bases
GTGTTGCGATATATACGCTTAATGTAAACGTATTAAAGTGGAAGCCGGGTATATTACTACCCGGTTTTTTATTGGTTGGA
AATAAAGCTAATTTGTTTAT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MYKFRIQGSDKPLSGEVTISGAKNAALPILFASLLAEEPVEVANVPKLRDVDTTMELLKRLGAEVSRNGSVHIDASGVND
FCAPYDLVKTMRASIWALGPLVARFGKGQVSLPGGCAIGARPVDLHIHGLEQLGATIKLEEGYVKAEVDGRLKGAHIVMD
KVSVGATITVMCAATLAEGTTVLENAAREPEIVDTANFLNAIGAKVSGMGTDTITIEGVERLGGGYHEVVADRIETGTFL
VAAAVSGGKIVCKNTKAHLLEAVLAKLEEAGADVQTGDDWISLDMTGRELKAVNIRTAPHPAFPTDMQAQFTLLNMMAKG
SGIITETIFENRFMHIPELQRMGAHAEIEGNTAICGDTDGLSGAQVMATDLRASASLVIAGCIAKGETIVDRIYHIARGY
DKIEDKLTALGANIERVHSDDL

Sequences:

>Translated_422_residues
MYKFRIQGSDKPLSGEVTISGAKNAALPILFASLLAEEPVEVANVPKLRDVDTTMELLKRLGAEVSRNGSVHIDASGVND
FCAPYDLVKTMRASIWALGPLVARFGKGQVSLPGGCAIGARPVDLHIHGLEQLGATIKLEEGYVKAEVDGRLKGAHIVMD
KVSVGATITVMCAATLAEGTTVLENAAREPEIVDTANFLNAIGAKVSGMGTDTITIEGVERLGGGYHEVVADRIETGTFL
VAAAVSGGKIVCKNTKAHLLEAVLAKLEEAGADVQTGDDWISLDMTGRELKAVNIRTAPHPAFPTDMQAQFTLLNMMAKG
SGIITETIFENRFMHIPELQRMGAHAEIEGNTAICGDTDGLSGAQVMATDLRASASLVIAGCIAKGETIVDRIYHIARGY
DKIEDKLTALGANIERVHSDDL
>Mature_422_residues
MYKFRIQGSDKPLSGEVTISGAKNAALPILFASLLAEEPVEVANVPKLRDVDTTMELLKRLGAEVSRNGSVHIDASGVND
FCAPYDLVKTMRASIWALGPLVARFGKGQVSLPGGCAIGARPVDLHIHGLEQLGATIKLEEGYVKAEVDGRLKGAHIVMD
KVSVGATITVMCAATLAEGTTVLENAAREPEIVDTANFLNAIGAKVSGMGTDTITIEGVERLGGGYHEVVADRIETGTFL
VAAAVSGGKIVCKNTKAHLLEAVLAKLEEAGADVQTGDDWISLDMTGRELKAVNIRTAPHPAFPTDMQAQFTLLNMMAKG
SGIITETIFENRFMHIPELQRMGAHAEIEGNTAICGDTDGLSGAQVMATDLRASASLVIAGCIAKGETIVDRIYHIARGY
DKIEDKLTALGANIERVHSDDL

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=79.5238095238095, Blast_Score=692, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44683; Mature: 44683

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKFRIQGSDKPLSGEVTISGAKNAALPILFASLLAEEPVEVANVPKLRDVDTTMELLKR
CEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHH
LGAEVSRNGSVHIDASGVNDFCAPYDLVKTMRASIWALGPLVARFGKGQVSLPGGCAIGA
HCCHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCC
RPVDLHIHGLEQLGATIKLEEGYVKAEVDGRLKGAHIVMDKVSVGATITVMCAATLAEGT
EEEEEEEECHHHCCCEEEEECCEEEEEECCCCCCEEEEEEECCCCCEEEEEEHHHHHCCH
TVLENAAREPEIVDTANFLNAIGAKVSGMGTDTITIEGVERLGGGYHEVVADRIETGTFL
HHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHCCCHHHHHHHHHCCCEEE
VAAAVSGGKIVCKNTKAHLLEAVLAKLEEAGADVQTGDDWISLDMTGRELKAVNIRTAPH
EEEECCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEEEECCCC
PAFPTDMQAQFTLLNMMAKGSGIITETIFENRFMHIPELQRMGAHAEIEGNTAICGDTDG
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHCCCCEEECCCEEEECCCCC
LSGAQVMATDLRASASLVIAGCIAKGETIVDRIYHIARGYDKIEDKLTALGANIERVHSD
CCCCCEEHHHHHCCCEEEEEEHHHCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHCCC
DL
CC
>Mature Secondary Structure
MYKFRIQGSDKPLSGEVTISGAKNAALPILFASLLAEEPVEVANVPKLRDVDTTMELLKR
CEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHH
LGAEVSRNGSVHIDASGVNDFCAPYDLVKTMRASIWALGPLVARFGKGQVSLPGGCAIGA
HCCHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCC
RPVDLHIHGLEQLGATIKLEEGYVKAEVDGRLKGAHIVMDKVSVGATITVMCAATLAEGT
EEEEEEEECHHHCCCEEEEECCEEEEEECCCCCCEEEEEEECCCCCEEEEEEHHHHHCCH
TVLENAAREPEIVDTANFLNAIGAKVSGMGTDTITIEGVERLGGGYHEVVADRIETGTFL
HHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHCCCHHHHHHHHHCCCEEE
VAAAVSGGKIVCKNTKAHLLEAVLAKLEEAGADVQTGDDWISLDMTGRELKAVNIRTAPH
EEEECCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEEEECCCC
PAFPTDMQAQFTLLNMMAKGSGIITETIFENRFMHIPELQRMGAHAEIEGNTAICGDTDG
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHCCCCEEECCCEEEECCCCC
LSGAQVMATDLRASASLVIAGCIAKGETIVDRIYHIARGYDKIEDKLTALGANIERVHSD
CCCCCEEHHHHHCCCEEEEEEHHHCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHCCC
DL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA